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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Rugen AM 5mg/5mg Capsule is used to treat hypertension (high blood pressure). It contains Amlodipine and Ramipril, which relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, thereby lowering blood pressure. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Mefro Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Rugen AM 5mg/5mg Capsule

Rugen AM 5mg/5mg Capsule is used to treat hypertension (high blood pressure). Hypertension is a medical condition, in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls. This condition makes the heart work harder to pump blood into the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Rugen AM 5mg/5mg Capsule contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure. It also decreases the body’s production of certain substances that raise blood pressure.

Your doctor will advise you how often you take Rugen AM 5mg/5mg Capsule based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Most of these side effects of Rugen AM 5mg/5mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Do not stop taking Rugen AM 5mg/5mg Capsule without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels, and kidney function is advised while taking Rugen AM 5mg/5mg Capsule. Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking any other medicines or have any allergic reactions to Rugen AM 5mg/5mg Capsule. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Rugen AM 5mg/5mg Capsule. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Rugen AM 5mg/5mg Capsule can be prescribed accordingly.

Uses of Rugen AM 5mg/5mg Capsule

Treatment of Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it. Try to take it at a fixed time every day. Do not double the dose if missed.

Medicinal Benefits

Rugen AM 5mg/5mg Capsule consists of Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle so that it receives more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure.

How Rugen AM 5mg/5mg Capsule Works

Rugen AM 5mg/5mg Capsule contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor). Amlodipine is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It also improves blood supply to the heart muscle to receive more oxygen, thus preventing chest pain. Ramipril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body and thereby lowering blood pressure. It also decreases the body’s production of certain substances that raise blood pressure.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Rugen AM 5mg/5mg Capsule

Do not take more than the prescribed dose of Rugen AM 5mg/5mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Rugen AM 5mg/5mg Capsule if you are allergic to Rugen AM 5mg/5mg Capsule or any of its components. Please inform your doctor if you are using any prescription and non-prescription medications you are taking, including vitamins, before starting Rugen AM 5mg/5mg Capsule. Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). Please consult your doctor if you plan to conceive, are pregnant, or are a breastfeeding mother before using Rugen AM 5mg/5mg Capsule. Rugen AM 5mg/5mg Capsule can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking aliskiren together with Rugen AM 5mg/5mg Capsule may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Rugen AM 5mg/5mg Capsule with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
AmlodipineDantrolene
Critical
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Using Rugen AM 5mg/5mg Capsule together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Rugen AM 5mg/5mg Capsule with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking Rugen AM 5mg/5mg Capsule together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Rugen AM 5mg/5mg Capsule together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
RamiprilPotassium citrate
Severe
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking Potassium citrate with Rugen AM 5mg/5mg Capsule may increase potassium levels in the blood. High potassium levels can lead to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Rugen AM 5mg/5mg Capsule, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Coadministration of Rugen AM 5mg/5mg Capsule with ketoconazole may increase the blood level of Rugen AM 5mg/5mg Capsule.

How to manage the interaction:
Although taking Rugen AM 5mg/5mg Capsule with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
RamiprilPotassium acetate
Severe
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking Rugen AM 5mg/5mg Capsule with potassium acetate may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm

How to manage the interaction:
Although there is a interaction between Rugen AM 5mg/5mg Capsule and Potassium acetate, but it can be taken if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking Rugen AM 5mg/5mg Capsule with Candesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Rugen AM 5mg/5mg Capsule together with Candesartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Coadministration of Rugen AM 5mg/5mg Capsule together with losartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Losartan with Rugen AM 5mg/5mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Taking Azilsartan medoxomil with Rugen AM 5mg/5mg Capsule may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Rugen AM 5mg/5mg Capsule together with Azilsartan medoxomil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, confusion, tingling in the hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
RamiprilEprosartan
Severe
How does the drug interact with Rugen AM 5mg/5mg Capsule:
Coadministration of Rugen AM 5mg/5mg Capsule together with eprosartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Rugen AM 5mg/5mg Capsule together with Eprosartan can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+RAMIPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+RAMIPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Rugen AM 5mg/5mg Capsule with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Rugen AM 5mg/5mg Capsule.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, use only one serving for women and two servings for men.

  • Quit smoking to lower the risk of heart diseases.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.

  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.

  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Rugen AM 5mg/5mg Capsule Substitute

Substitutes safety advice
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Alcohol

Caution

Alcohol may lower your blood pressure. It would help if you avoided or limit consuming alcohol.

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Pregnancy

Caution

It is advised to seek medical advice before using Rugen AM 5mg/5mg Capsule if you plan to conceive or a pregnant before using Rugen AM 5mg/5mg Capsule.

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Breast Feeding

Caution

There are limited studies on how Rugen AM 5mg/5mg Capsule affects breastfed infants. Please consult your doctor before using Rugen AM 5mg/5mg Capsule if you are a lactating mother.

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Driving

Caution

Rugen AM 5mg/5mg Capsule may cause side effects due to lowering of the blood pressure such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Rugen AM 5mg/5mg Capsule. Rugen AM 5mg/5mg Capsule is to be administered with caution in patients with severe hepatic impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Rugen AM 5mg/5mg Capsule. Rugen AM 5mg/5mg Capsule is primarily eliminated by the kidney and can be accumulated in patients with renal impairment.

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Children

Unsafe

Rugen AM 5mg/5mg Capsule is not recommended for use in children as the efficacy and safety has not been established.

Have a query?

FAQs

Rugen AM 5mg/5mg Capsule is used to treat hypertension (high blood pressure), a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessel's walls.

Rugen AM 5mg/5mg Capsule consists of Amlodipine and Ramipril. Amlodipine relaxes blood vessels, so that blood passes through them easily thereby lowering the blood pressure. Ramipril relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body thereby lowering the raised blood pressure.

Rugen AM 5mg/5mg Capsule is recommended to use in dose and duration as advised by the doctor. Do not stop taking Rugen AM 5mg/5mg Capsule on your own as it may lead to a sudden rise in blood pressure increases the risk of heart attack and stroke.

Rugen AM 5mg/5mg Capsule can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.

Amlodipine in Rugen AM 5mg/5mg Capsule can cause ankle swelling upon long term use. Please try to keep your feet at the elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.

Rugen AM 5mg/5mg Capsule may increase blood potassium levels in people with diabetes, poor kidney function and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Rugen AM 5mg/5mg Capsule if you have diabetes.

Even though your blood pressure becomes normal after using Rugen AM 5mg/5mg Capsule, it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Excessive alcohol consumption can lower blood pressure further and increase the risk of side effects. It's best to limit or avoid alcohol while taking this medication.

Common side effects of Rugen AM 5mg/5mg Capsule may include blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache and swelling of the ankles or feet. Most of these side effects of Rugen AM 5mg/5mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, please contact your doctor.

Rugen AM 5mg/5mg Capsule is generally not recommended for pregnant women. If you're pregnant or planning to become pregnant, discuss this with your doctor.

Your doctor will determine the appropriate dosage and frequency based on your needs. It's essential to follow the prescribed instructions.

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

No, stopping Amlodipine Ramipril suddenly can cause a sudden increase in blood pressure. Your doctor will gradually reduce your dosage to help prevent this.

Your doctor will schedule regular follow-up appointments to monitor your blood pressure and check for side effects. It's essential to attend these appointments.

Rugen AM 5mg/5mg Capsule contains Amlodipine (calcium channel blocker) and Ramipril (angiotensin-converting enzyme inhibitor).

If you are allergic to Rugen AM 5mg/5mg Capsule, seek medical attention immediately. Symptoms may include hives, swelling of the face or throat, and difficulty breathing.

If you experience side effects from Rugen AM 5mg/5mg Capsule, talk to your doctor. They may be able to adjust your dose or switch you to a different medication.

Country of origin

India

Manufacturer/Marketer address

F-67-68 Phase- Vii, Industrial Area,Mohali -160055 Punjab, (India)
Other Info - RUGE321

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