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  1. Home
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  3. S Lactone 50 Tablet 10's

Prescription drug
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S Lactone 50 Tablet 10's, Pack of 10
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

S Lactone 50 Tablet 10's is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. It contains Spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, this medication may cause common side effects, including low blood pressure, dehydration, drowsiness, dizziness, high potassium levels, low sodium levels, elevated creatinine levels, headaches, breast enlargement in males, and absence of menstrual periods in females. Before taking this medication, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Composition :

SPIRONOLACTONE-50MG

Manufacturer/Marketer :

Steris Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About S Lactone 50 Tablet 10's

S Lactone 50 Tablet 10's is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). Oedema is associated with pulmonary hypertension (high blood pressure in the lungs) or heart failure (irregular heart pumping).

S Lactone 50 Tablet 10's contains spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease.

In some cases, S Lactone 50 Tablet 10's may cause common side effects such as hypotension, dehydration, drowsiness, dizziness, hyperkalaemia, hyponatraemia, elevated creatinine levels, headache, vomiting, nausea, diarrhoea, fatigue, and weakness. Most of these side effects of S Lactone 50 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you are allergic to any of its ingredients. Do not stop taking S Lactone 50 Tablet 10's of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Let your doctor know if you have any kidney, liver, or heart disease. S Lactone 50 Tablet 10's is not recommended during pregnancy unless strongly suggested by your doctor.

Uses of S Lactone 50 Tablet 10's

S Lactone 50 Tablet 10's is primarily used in the treatment of oedema and hypertension. It is effective in managing the following conditions:

  • Oedema (Fluid Retention): S Lactone 50 Tablet 10's is used to treat oedema associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It helps remove excess fluid in the body by increasing the urine output from the kidneys.
  • Hypertension (High Blood Pressure): S Lactone 50 Tablet 10's helps lower high blood pressure by blocking aldosterone, thereby reducing water and sodium retention.
  • Heart failure: S Lactone 50 Tablet 10's is prescribed to improve survival and reduce hospitalisation in patients with severe heart failure, particularly those with NYHA Class III-IV symptoms who are not responding adequately to standard treatments.
  • Hypokalaemia (Low Blood Potassium Levels): S Lactone 50 Tablet 10's is effective in treating or preventing low potassium levels, especially in patients taking digitalis or when other therapies are ineffective.
  • Primary Hyperaldosteronism (Conn's Syndrome): S Lactone 50 Tablet 10's is used in both the treatment and diagnosis of this condition, helping to manage associated hypertension and hypokalaemia.
  • Ascites (Abdominal Fluid Buildup): In patients with cirrhosis (liver disease), S Lactone 50 Tablet 10's is used in combination with water pills/loop diuretics (such as furosemide) to manage ascites by enhancing fluid removal.

Have a query?

Directions for Use

  • S Lactone 50 Tablet 10's can be taken with or without food. However, taking it with food may help reduce side effects like nausea (feeling sick).
  • It is usually taken once daily in the morning; however, your doctor may adjust the dose of this medication based on your medical condition.
  • Swallow the medication as a whole with water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease.
  • It helps reduce/ lower your blood pressure.
  • Reduces the risk of cardiovascular problems like stroke and heart attacks.
  • Reduces oedema and prevents heart tissue damage in heart failure patients.
  • Also, helps reduce hospital stay and increase survival rates in symptomatic heart failure patients.
  • It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure.

How S Lactone 50 Tablet 10's Works

S Lactone 50 Tablet 10's contains spironolactone (a short-acting diuretic), which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of S Lactone 50 Tablet
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Practice good hygiene by washing the vaginal area with water and mild soap.
  • Wear breathable cotton underwear and avoid scented products.
  • Check vaginal secretion changes, including colour, texture, amount, and smell.
  • Be aware of potential causes like infection or pregnancy.
  • Consult a doctor if secretions are unusual, or smelly with pain.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
  • If you experience a lack of energy due to liver conditions, consult your doctor to determine the underlying cause and further management.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine instead drink plenty of water.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of S Lactone 50 Tablet 10's

Do not take more than the prescribed dose of S Lactone 50 Tablet 10's, as it may cause an overdose. The symptoms of an overdose include feeling thirsty, urinating more than usual, diarrhoea, feeling or being sick, confusion, high potassium levels in blood, or dizziness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take S Lactone 50 Tablet 10's if you are allergic to any of its ingredients.
  • Avoid taking S Lactone 50 Tablet 10's if you have low blood pressure (less than 90 mm of Hg), severe kidney disease (with creatinine clearance less than 30 mL/min), liver disease, hyperkalaemia (high potassium levels), hyponatraemia (low sodium levels), or a history of heart attack.
  • S Lactone 50 Tablet 10's is also contraindicated in hypotension (low blood pressure), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (inability to urinate), diabetes (high blood sugar), and aortic stenosis (heart valve problem).
  • S Lactone 50 Tablet 10's is not recommended during pregnancy unless clearly advised by your doctor.
  • Please consult your doctor so that the dosage of S Lactone 50 Tablet 10's can be prescribed accordingly.
  • Breastfeeding should be avoided during treatment with S Lactone 50 Tablet 10's.
  • Do not stop taking S Lactone 50 Tablet 10's of your own, as doing so may raise your blood pressure and increase the risk of heart disease and stroke.
  • Avoid taking any extra potassium supplements or consuming potassium-rich foods (such as bananas and broccoli) while using S Lactone 50 Tablet 10's, as this may lead to an excessive increase in blood potassium levels (hyperkalaemia).
  • Do not take S Lactone 50 Tablet 10's if you are also using potassium-sparing diuretics (such as eplerenone) or a combination of an angiotensin receptor blocker (ARB) and an angiotensin-converting enzyme (ACE) inhibitor.

Drug-Drug Interactions

verifiedApollotooltip
SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with S Lactone 50 Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between S Lactone 50 Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with S Lactone 50 Tablet:
Coadministration of Amiloride with S Lactone 50 Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with S Lactone 50 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactonePazopanib
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking S Lactone 50 Tablet with pazopanib may significantly increase the blood levels of pazopanib. This could increase the risk of severe adverse effects.

How to manage the interaction:
Although taking S Lactone 50 Tablet and pazopanib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, chest pain, pain in your arms, back, neck, or jaw, slurred speech or difficulty speaking, shortness of breath. Do not stop using any medications without consulting doctor.
SpironolactoneEnalapril
Severe
How does the drug interact with S Lactone 50 Tablet:
Coadministration of enalapril with S Lactone 50 Tablet may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Enalapril together with S Lactone 50 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, coconut water, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
SpironolactoneIrbesartan
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking Irbesartan with S Lactone 50 Tablet may increase potassium levels in the blood, which may lead to side effects.

How to manage the interaction:
Taking Irbesartan with S Lactone 50 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctors advise.
SpironolactoneLosartan
Severe
How does the drug interact with S Lactone 50 Tablet:
Coadministration of Losartan with S Lactone 50 Tablet can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with S Lactone 50 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneTrimethoprim
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking S Lactone 50 Tablet with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking S Lactone 50 Tablet and trimethoprim together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneTelmisartan
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking S Lactone 50 Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with S Lactone 50 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
SpironolactoneLithium
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking lithium and S Lactone 50 Tablet may increase blood levels of lithium.

How to manage the interaction:
Although taking S Lactone 50 Tablet and lithium together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as loose stools, vomiting, drowsiness, shaking, thirst, lack of coordination, or muscle weakness. Do not stop using any medications without consulting doctor.
SpironolactoneEprosartan
Severe
How does the drug interact with S Lactone 50 Tablet:
Taking S Lactone 50 Tablet with eprosartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking S Lactone 50 Tablet and eprosartan together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise, like walking, improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

All Substitutes & Brand Comparisons

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Alcohol

Caution

You are recommended not to consume alcohol along with S Lactone 50 Tablet 10's to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

S Lactone 50 Tablet 10's is not recommended during pregnancy unless strongly advised by your doctor. Please consult your doctor so that the dosage of S Lactone 50 Tablet 10's can be prescribed accordingly.

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Breast Feeding

Unsafe

Breastfeeding should be avoided during treatment with S Lactone 50 Tablet 10's.

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Driving

Unsafe

It is not recommended to drive after taking S Lactone 50 Tablet 10's, as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

S Lactone 50 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver condition.

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Kidney

Caution

S Lactone 50 Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney condition.

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Children

Unsafe

S Lactone 50 Tablet 10's is not recommended for children below 12 years of age, as its safety and effectiveness have not been established.

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Heart

Safe if prescribed

S Lactone 50 Tablet 10's is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

S Lactone 50 Tablet 10's should be used with caution in geriatric patients as it can cause side effects, including increased potassium levels in some cases. Please consult your physician.

FAQs

S Lactone 50 Tablet 10's is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure.

S Lactone 50 Tablet 10's contains spironolactone (a short-acting diuretic) that increases the amount of urine excreted by the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Yes, S Lactone 50 Tablet 10's may affect the menstrual cycle. It can lead to irregular and painful periods. In addition to this, taking S Lactone 50 Tablet 10's can also lead to pain and swelling of the breast. If any of these problems persist and discomfort increases, please consult your doctor for the best advice.

S Lactone 50 Tablet 10's is known to increase the blood potassium level. So, if you take any extra potassium supplements or potassium-rich foods such as bananas and broccoli, it may lead to an excessive increase in potassium level and lead to hyperkalemia.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Country of origin

India

Manufacturer/Marketer address

A.O. : 328-A, Tanaji Chowk, New Mill Road, Kurla (West), Mumbai 400070.
Other Info - SLA0023

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:22 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/012151s068lbl.pdf
  2. https://www.accord-healthcare.com/ie/system/files/pil/spironolactone_pil.pdf
  3. https://www.drugs.com/spironolactone.html#
  4. https://www.drugs.com/uk/pdf/leaflet/845899.pdf
  5. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=b34d5a28-2a1d-e75b-e053-2a95a90a99f4
  6. https://www.nps.org.au/assets/medicines/e8ab1237-c1d0-43b6-9558-acb400d9e917.pdf
  7. https://www.nhs.uk/medicines/spironolactone/how-and-when-to-take-spironolactone/

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