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  3. Sandimmun Neoral 100 mg Capsule 5's

Sandimmun Neoral 100 mg Capsule 5's, Pack of 5 TABLETS
Sandimmun Neoral 100 mg Capsule 5's, Pack of 5 TABLETS
Sandimmun Neoral 100 mg Capsule 5's, Pack of 5 TABLETS
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Synonym :

CYCLOSPORIN

Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sandimmun Neoral 100 mg Capsule

Sandimmun Neoral 100 mg Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis. Organ transplant rejection occurs when the immune system attacks a transplanted organ. Psoriasis is a long-lasting, inflammatory skin illness.  Rheumatoid arthritis is an autoimmune disease, where the body's immune system attacks its own tissue, leading to joint pain and damage.

Sandimmun Neoral 100 mg Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation), which are needed for T cells to activate and attack the body. Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

You are advised to take Sandimmun Neoral 100 mg Capsule for as long as your doctor has prescribed it, depending on your medical condition. You may experience headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Sandimmun Neoral 100 mg Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Before taking Sandimmun Neoral 100 mg Capsule, inform your doctor if you have any allergies, kidney disease, uncontrolled high blood pressure, or any type of cancer. Sandimmun Neoral 100 mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and any medications you are taking to help rule out any potential unpleasant side effects.

Uses of Sandimmun Neoral 100 mg Capsule

Treatment of Organ Transplant Rejection: Sandimmun Neoral 100 mg Capsule is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It helps prevent organ rejection by suppressing the immune system.
Treatment of Psoriasis: Sandimmun Neoral 100 mg Capsule is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
Treatment of Rheumatoid Arthritis: Sandimmun Neoral 100 mg Capsule is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Directions for Use

  • Sandimmun Neoral 100 mg Capsule ideally should be given 12 hours apart. It should be taken with water and swallowed whole.
  • Grapefruit and grapefruit juice should be avoided as they can raise ciclosporin levels in the blood. 

Medicinal Benefits

Sandimmun Neoral 100 mg Capsule is an immunosuppressant medication used to prevent organ transplant rejection. It contains cyclosporine, which suppresses the immune system and prevents your body from rejecting a new organ. It helps reduce rapid skin cell growth and inflammation caused by psoriasis. Additionally, it helps reduce pain and inflammation in the joints and slows down joint damage caused by an overactive immune system in people with rheumatoid arthritis.

How Sandimmun Neoral 100 mg Capsule Works

Sandimmun Neoral 100 mg Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation), which are needed for T cells to activate and attack the body. Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sandimmun Neoral 100 mg Capsule
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.

What if I have taken an overdose of Sandimmun Neoral 100 mg Capsule

Take Sandimmun Neoral 100 mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Sandimmun Neoral 100 mg Capsule if you are allergic to any immunosuppressant medicines or Cyclosporine. Let your doctor know if you have liver or kidney problems, high blood pressure, low magnesium levels, or high potassium levels. Your Sandimmun Neoral 100 mg Capsule may make you more susceptible to infections. Consult your doctor if you develop any signs of severe conditions, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Sandimmun Neoral 100 mg Capsule inform your doctor if you have any type of cancer. Sandimmun Neoral 100 mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and any medications you are taking to help rule out any potential unpleasant side effects.

Drug-Drug Interactions

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CiclosporinPitavastatin
Critical
CiclosporinSimvastatin
Critical

Drug-Drug Interactions

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CiclosporinPitavastatin
Critical
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Coadministration of pitavastatin with Sandimmun Neoral 100 mg Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Sandimmun Neoral 100 mg Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinSimvastatin
Critical
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Combining Sandimmun Neoral 100 mg Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Sandimmun Neoral 100 mg Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Sandimmun Neoral 100 mg Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Sandimmun Neoral 100 mg Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinBosentan
Critical
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Sandimmun Neoral 100 mg Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinCladribine
Severe
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Using cladribine together with Sandimmun Neoral 100 mg Capsule may increase the risk of infections.

How to manage the interaction:
Although taking cladribine and Sandimmun Neoral 100 mg Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinLercanidipine
Severe
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.

How to manage the interaction:
Co-administration of Sandimmun Neoral 100 mg Capsule with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
CiclosporinTriamterene
Severe
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Taking Triamterene with Cyclosporine can increase the risk of hyperkalemia(high levels of potassium in blood).

How to manage the interaction:
Taking Sandimmun Neoral 100 mg Capsule with Triamterene together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
CiclosporinOrlistat
Severe
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Coadministration of Sandimmun Neoral 100 mg Capsule with Orlistat can reduce the levels and effects of Sandimmun Neoral 100 mg Capsule.

How to manage the interaction:
Although there is a possible interaction between Orlistat and Sandimmun Neoral 100 mg Capsule, you can take these medicines together when prescribed by your doctor. Do not stop using any medications without talking to a doctor.
CiclosporinFoscarnet
Severe
How does the drug interact with Sandimmun Neoral 100 mg Capsule:
Co-administration of foscarnet with Sandimmun Neoral 100 mg Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between foscarnet and Sandimmun Neoral 100 mg Capsule, they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Sandimmun Neoral 100 mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Sandimmun Neoral 100 mg Capsule. It could lead to increased dizziness and drowsiness.

bannner image

Pregnancy

Caution

It is not known whether Sandimmun Neoral 100 mg Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

bannner image

Breast Feeding

Unsafe

It is not recommended to take Sandimmun Neoral 100 mg Capsule while you are breastfeeding. Sandimmun Neoral 100 mg Capsule passes into breast milk.

bannner image

Driving

Caution

Drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Take Sandimmun Neoral 100 mg Capsule only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

bannner image

Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Sandimmun Neoral 100 mg Capsule.

bannner image

Children

Unsafe

Sandimmun Neoral 100 mg Capsule should not be given to children, as the efficacy and safety have not been established.

Have a query?

FAQs

Sandimmun Neoral 100 mg Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Sandimmun Neoral 100 mg Capsule acts as an immunosuppressant, which helps reduce pain and inflammation in the joints and prevent joint stiffness, thereby relieving rheumatoid arthritis.

If you miss a dose of Sandimmun Neoral 100 mg Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Sandimmun Neoral 100 mg Capsule. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, using Sandimmun Neoral 100 mg Capsule may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.

Sandimmun Neoral 100 mg Capsule is known to decrease the immune system. As a result, it increases your risk of developing certain types of cancer, especially skin cancer. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.

No, Sandimmun Neoral 100 mg Capsule is not a steroid. It is an immunosuppressant.

Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.

Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.

Sandimmun Neoral 100 mg Capsule is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.

Sandimmun Neoral 100 mg Capsule has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.

Common side effects of Sandimmun Neoral 100 mg Capsule may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Sandimmun Neoral 100 mg Capsule ideally should be given 12 hours apart. The capsules should be taken with water and swallowed whole. Grapefruit and grapefruit juice should be avoided, as they can increase ciclosporin levels in the blood.

The duration of Sandimmun Neoral 100 mg Capsule treatment varies depending on the underlying condition and individual response.

Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Sandimmun Neoral 100 mg Capsule. They can help you identify potential interactions and recommend safe alternatives if necessary.

Yes, you can travel while taking cyclosporine. However, it's essential to plan and take necessary precautions. Ensure you have a sufficient supply of your medication, and be aware of any potential customs regulations or travel restrictions.

Generally, moderate exercise is safe while taking Sandimmun Neoral 100 mg Capsule. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.

Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.

Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.

If you miss a dose of Sandimmun Neoral 100 mg Capsule, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Some people may experience mood changes or anxiety while taking Sandimmun Neoral 100 mg Capsule. If you notice any changes in your mental health, it's important to talk to your doctor.

Sandimmun Neoral 100 mg Capsule occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.

Sandimmun Neoral 100 mg Capsule contains cyclosporine, an immunosuppressant.

Sandimmun Neoral 100 mg Capsule should not be given to children, as the efficacy and safety have not been established.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - SAN0040

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 22, 2025 | 1:53 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050715s035,050716s038lbl.pdf
  2. https://www.mayoclinic.org/drugs-supplements/cyclosporine-oral-route/description/drg-20075815
  3. https://medlineplus.gov/druginfo/meds/a601207.html
  4. https://www.drugs.com/disease-interactions/cyclosporine.html
  5. https://www.medicines.org.uk/emc/files/pil.5300.pdf
  6. https://www.webmd.com/drugs/2/drug-5645-9108/cyclosporine-oral/cyclosporine-oral/details

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