Sandimmun Neoral 100mg/ml Solution 50 ml
MRP ₹4230
(Inclusive of all Taxes)
₹507.6 Cashback (12%)
Extra 15% Off with Bank Offers
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Genuine Products
Synonym :
CYCLOSPORIN
Composition :
CYCLOSPORINE-100MG
Manufacturer/Marketer :
Novartis India Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About Sandimmun Neoral 100mg/ml Solution
Sandimmun Neoral 100mg/ml Solution belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.
Sandimmun Neoral 100mg/ml Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.
Sandimmun Neoral 100mg/ml Solution may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.
To treat your condition effectually, continue taking Sandimmun Neoral 100mg/ml Solution for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.
Uses of Sandimmun Neoral 100mg/ml Solution
Sandimmun Neoral 100mg/ml Solution is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Sandimmun Neoral 100mg/ml Solution are as follows:
- Treatment of Organ Transplant Rejection: Sandimmun Neoral 100mg/ml Solution is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
- Treatment of Psoriasis: Sandimmun Neoral 100mg/ml Solution is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
- Treatment of Rheumatoid Arthritis: Sandimmun Neoral 100mg/ml Solution is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.
Have a query?
Directions for Use
- Sandimmun Neoral 100mg/ml Solution can be taken with or without food. However, avoid taking it with grapefruit, pineapple, or papaya juice, as they may increase the amount of this medication in your blood.
- It is usually taken 2 times a day or as prescribed by your doctor.
- Swallow the whole capsule with a glass of water.
- Do not crush, chew, or open it.
Medicinal Benefits
- Sandimmun Neoral 100mg/ml Solution suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
- It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
- Sandimmun Neoral 100mg/ml Solution helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
- It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
- This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
- It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
- Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
- It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.
How Sandimmun Neoral 100mg/ml Solution Works
Sandimmun Neoral 100mg/ml Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.
Storage
• Store in a cool and dry place away from sunlight.• Keep Sandimmun Neoral 100mg/ml Solution out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sandimmun Neoral 100mg/ml Solution 50 ml
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Confusion is a major psychotic disorder that needs immediate medical attention.
- Acknowledge your experience and put effort to control confusion.
- Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
- Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
- Talk to your dietician and consume food that can improve your mental health.
- Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
- A warm compress and washing the eyes with water can help with crusting on the eyelids.
- Avoid wearing contact lens until you feel better; use spectacles instead.
- Do not rub the eyes.
- Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
- Reduce salt intake to minimize fluid buildup.
- Use compression stockings, sleeves, or gloves.
- Gently massage the affected area towards the heart.
- Protect the swollen area from injury and keep it clean.
- Use lotion or cream to keep the skin moisturized.
- Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
- Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
- Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
- Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
- Keep your nails short to reduce the risk of breakage and snagging.
- Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
- Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.
What if I have taken an overdose of Sandimmun Neoral 100mg/ml Solution
Take Sandimmun Neoral 100mg/ml Solution only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, and liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
Drug Warnings
- Do not take Sandimmun Neoral 100mg/ml Solution if you are allergic to any of the components.
- Let your doctor know before using Sandimmun Neoral 100mg/ml Solution if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
- Sandimmun Neoral 100mg/ml Solution may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
- Before taking Sandimmun Neoral 100mg/ml Solution, inform your doctor if you have any type of cancer.
- Consult your doctor before taking Sandimmun Neoral 100mg/ml Solution if you are pregnant or planning for pregnancy.
- Sandimmun Neoral 100mg/ml Solution should not be taken by breastfeeding mothers as it passes into breast milk.
- Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Critical
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Coadministration of pitavastatin with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Sandimmun Neoral 100mg/ml Solution 50 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Coadministration of pitavastatin with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Sandimmun Neoral 100mg/ml Solution 50 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Combining Sandimmun Neoral 100mg/ml Solution 50 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Combining Sandimmun Neoral 100mg/ml Solution 50 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Critical
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Sandimmun Neoral 100mg/ml Solution 50 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Co-administration of pazopanib with Sandimmun Neoral 100mg/ml Solution 50 ml can increase the blood levels of pazopanib which increases the risk of side effects.
How to manage the interaction:
Taking pazopanib with Sandimmun Neoral 100mg/ml Solution 50 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience notice any symptoms of nausea, vomiting, diarrhea, abdominal pain, dizziness, fatigue, headache, tremors (shaking), seizures(fits), fever, sore throat, unusual bruising or bleeding, and increased or decreased urination contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of pazopanib with Sandimmun Neoral 100mg/ml Solution 50 ml can increase the blood levels of pazopanib which increases the risk of side effects.
How to manage the interaction:
Taking pazopanib with Sandimmun Neoral 100mg/ml Solution 50 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience notice any symptoms of nausea, vomiting, diarrhea, abdominal pain, dizziness, fatigue, headache, tremors (shaking), seizures(fits), fever, sore throat, unusual bruising or bleeding, and increased or decreased urination contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinZalcitabine
Severe
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Co-administration of zalcitabine with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly decrease the effect of zalcitabine.
How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Sandimmun Neoral 100mg/ml Solution 50 ml, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of zalcitabine with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly decrease the effect of zalcitabine.
How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Sandimmun Neoral 100mg/ml Solution 50 ml, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.
How to manage the interaction:
Co-administration of Sandimmun Neoral 100mg/ml Solution 50 ml with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.
How to manage the interaction:
Co-administration of Sandimmun Neoral 100mg/ml Solution 50 ml with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.
How to manage the interaction:
There may be a possibility of interaction between cisapride and Sandimmun Neoral 100mg/ml Solution 50 ml, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.
How to manage the interaction:
There may be a possibility of interaction between cisapride and Sandimmun Neoral 100mg/ml Solution 50 ml, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Sandimmun Neoral 100mg/ml Solution 50 ml:
Coadministration of docetaxel with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly increase the blood levels of docetaxel.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Sandimmun Neoral 100mg/ml Solution 50 ml, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
Coadministration of docetaxel with Sandimmun Neoral 100mg/ml Solution 50 ml may significantly increase the blood levels of docetaxel.
How to manage the interaction:
Although there is a possible interaction between deferasirox and Sandimmun Neoral 100mg/ml Solution 50 ml, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
- Practising yoga may also help improve joint flexibility and manage pain.
- Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
- Get adequate sleep, as rest can help reduce inflammation and swelling.
- Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
- De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
- Acupuncture, massage, and physical therapy may also be helpful.
- Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
- Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
- Avoid smoking and alcohol consumption.
Habit Forming
No
Therapeutic Class
IMMUNOSUPPRESSANTS
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Alcohol
Caution
You are recommended to avoid alcohol consumption while taking Sandimmun Neoral 100mg/ml Solution. It could lead to increased dizziness and drowsiness.
Pregnancy
Caution
It is not known whether Sandimmun Neoral 100mg/ml Solution will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.
Breast Feeding
Unsafe
It is not recommended to take Sandimmun Neoral 100mg/ml Solution while you are breastfeeding. Sandimmun Neoral 100mg/ml Solution passes into breast milk.
Driving
Caution
Drive or operate machinery only if you are alert.
Liver
Caution
Take Sandimmun Neoral 100mg/ml Solution only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.
Kidney
Consult your doctor
Please consult your doctor if you have kidney impairment before taking Sandimmun Neoral 100mg/ml Solution.
Children
Unsafe
Sandimmun Neoral 100mg/ml Solution should not be given to children, as the efficacy and safety have not been established.
Heart
Please consult your doctor if you have a history of heart disease before taking Sandimmun Neoral 100mg/ml Solution. Your doctor will prescribe it only if the benefits outweigh the risks.
Geriatrics
Caution
Sandimmun Neoral 100mg/ml Solution should be given with caution in elderly patients due to an increased risk of side effects. Talk to your doctor if you have any concerns.
FAQs
Country of origin
India
Manufacturer/Marketer address
Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India.
Other Info - SAN0070
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Author Details
Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050715s035,050716s038lbl.pdf
- https://www.mayoclinic.org/drugs-supplements/cyclosporine-oral-route/description/drg-20075815
- https://medlineplus.gov/druginfo/meds/a601207.html
- https://www.drugs.com/disease-interactions/cyclosporine.html
- https://www.medicines.org.uk/emc/files/pil.5300.pdf
- https://www.webmd.com/drugs/2/drug-5645-9108/cyclosporine-oral/cyclosporine-oral/details
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