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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Seretide 250 Evohaler 120 mdi is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). It contains Salmeterol and Fluticasone, which relax the muscles in the airways and increase airflow to the lungs. It makes breathing easier by widening the airways. Also, it acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. It may cause common side effects such as nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type :

INHALATION

Return Policy :

Not Returnable

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About Seretide 250 Evohaler 120 mdi

Seretide 250 Evohaler 120 mdi is a respiratory medication used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing disorder characterised by airway narrowing, swelling, and excessive mucus production, resulting in difficulty breathing. COPD is a group of lung diseases that includes emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of the bronchial tubes).

Seretide 250 Evohaler 120 mdi is a combination of two medicines: Salmeterol and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take Seretide 250 Evohaler 120 mdi based on your medical condition. The common side effects of Seretide 250 Evohaler 120 mdi include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Seretide 250 Evohaler 120 mdi do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking Seretide 250 Evohaler 120 mdi. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since there is a chance of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of Seretide 250 Evohaler 120 mdi

Seretide 250 Evohaler 120 mdi is used to treat and prevent breathing problems associated with asthma and chronic obstructive pulmonary disease (COPD). The detailed uses of Seretide 250 Evohaler 120 mdi are as follows: <br/>• Treatment of asthma: Used to relieve and prevent difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness in people with asthma.<br/>• Management of chronic obstructive pulmonary disease (COPD): Seretide 250 Evohaler 120 mdi controls and minimises symptoms such as wheezing, dyspnea, coughing, and chest tightness in patients with COPD, including chronic bronchitis and emphysema.<br/>• Control of COPD flare-ups: Reduces the frequency and severity of COPD exacerbations while improving overall lung function.<br/>• Anti-inflammatory effect: Fluticasone reduces airway irritation, which makes breathing easier.<br/>• Long-acting bronchodilation: Salmeterol relaxes the airway muscles, helping breathing become easier over time.<br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Please read the instruction leaflet and use it as suggested by your doctor.
  • Rinse your mouth with water and spit it out after using Seretide 250 Evohaler 120 mdi to avoid fungal infections in the mouth and throat.

Medicinal Benefits

Seretide 250 Evohaler 120 mdi is used to treat and prevent respiratory disorders, such as asthma attacks and chronic obstructive pulmonary disease (COPD). Seretide 250 Evohaler 120 mdi improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Seretide 250 Evohaler 120 mdi is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

How Seretide 250 Evohaler 120 mdi Works

Seretide 250 Evohaler 120 mdi is a combination of two medicines: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Storage

Keep out of sight and reach of children.
Side effects of Seretide 250 Evohaler 120 mdi
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.

What if I have taken an overdose of Seretide 250 Evohaler 120 mdi

Do not use Seretide 250 Evohaler 120 mdi in more doses or more often than prescribed, as it may cause an overdose. The symptoms of overdose include chest pain, dry mouth, confusion, decreased urine output, loss of appetite, high blood pressure, nervousness or mood changes. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not stop taking this medicine on your own unless advised by your doctor. Before taking Seretide 250 Evohaler 120 mdi, let your doctor know if you have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. Seretide 250 Evohaler 120 mdi may cause hypokalemia (low potassium levels in the blood); therefore, it should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects. Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis, since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. Seretide 250 Evohaler 120 mdi can cause a rise in blood glucose levels. Hence, monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using Seretide 250 Evohaler 120 mdi. Avoid drinking alcohol while taking this medicine, as it can worsen your side effects.

Drug-Drug Interactions

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SalmeterolCobicistat
Severe

Drug-Drug Interactions

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How does the drug interact with Seretide 250 Evohaler 120 mdi:
Co-administration of Seretide 250 Evohaler 120 mdi with Mifepristone may make Seretide 250 Evohaler 120 mdi less effective as a therapy.

How to manage the interaction:
Taking Seretide 250 Evohaler 120 mdi with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
SalmeterolCobicistat
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Cobicistat may significantly increase the blood levels of Seretide 250 Evohaler 120 mdi. High blood levels of Seretide 250 Evohaler 120 mdi can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Seretide 250 Evohaler 120 mdi with Cobicistat can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolTelithromycin
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Telithromycin may significantly increase the blood levels of Seretide 250 Evohaler 120 mdi. High blood levels of Seretide 250 Evohaler 120 mdi can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Seretide 250 Evohaler 120 mdi and Telithromycin, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SalmeterolTelaprevir
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Co-administration of Telaprevir and Seretide 250 Evohaler 120 mdi can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Seretide 250 Evohaler 120 mdi with Telaprevir together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolCarteolol
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
The combined use of Carteolol and Seretide 250 Evohaler 120 mdi can reduce the effect of Seretide 250 Evohaler 120 mdi.

How to manage the interaction:
Taking Seretide 250 Evohaler 120 mdi with Carteolol together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Using levobunolol ophthalmic together with Seretide 250 Evohaler 120 mdi may reduce the benefits of both medications. It may increase the risk of severe asthmatic attacks or breathing problems.

How to manage the interaction:
There may be a possibility of interaction between Seretide 250 Evohaler 120 mdi and Levobunolol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
SalmeterolNadolol
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Coadministration of Nadolol with Seretide 250 Evohaler 120 mdi can reduce the action of both the medications. It may also increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Although taking Seretide 250 Evohaler 120 mdi and Nadolol together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
SalmeterolNefazodone
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Nefazodone may significantly increase the blood levels of Seretide 250 Evohaler 120 mdi. High blood levels of Seretide 250 Evohaler 120 mdi can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Seretide 250 Evohaler 120 mdi and Nefazodone, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Seretide 250 Evohaler 120 mdi:
Co-administration of Seretide 250 Evohaler 120 mdi and itraconazole can increase the risk of developing an irregular heartbeat.

How to manage the interaction:
Seretide 250 Evohaler 120 mdi and itraconazole have the potential to interact, however, they can still be used if a doctor prescribes them. If you suffer any of the following symptoms, seek medical attention: dizziness, lightheadedness, fainting, shortness of breath, or racing heartbeats. Never discontinue taking a drug without consulting a doctor.
SalmeterolIdelalisib
Severe
How does the drug interact with Seretide 250 Evohaler 120 mdi:
The combined use of Idelalisib and Seretide 250 Evohaler 120 mdi can increase the risk of irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Seretide 250 Evohaler 120 mdi and Idelalisib, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Seretide 250 Evohaler 120 mdi.
  • Know your triggers, such as allergens, such as pollen, dust, and food items, that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

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Pregnancy

Caution

Please consult your doctor if you are planning to conceive or are already pregnant before starting Seretide 250 Evohaler 120 mdi.

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Breast Feeding

Caution

There is limited data on how Seretide 250 Evohaler 120 mdi affects breastfeeding. Please consult your doctor before starting Seretide 250 Evohaler 120 mdi.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness and an increased or uneven heart rate while using Seretide 250 Evohaler 120 mdi. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Seretide 250 Evohaler 120 mdi should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Seretide 250 Evohaler 120 mdi.

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Kidney

Caution

Seretide 250 Evohaler 120 mdi should be used with caution in patients with kidney diseases. Inform your doctor if you have a history of kidney disease. Your doctor will weigh the benefits and potential risks before prescribing Seretide 250 Evohaler 120 mdi.

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Children

Caution

Seretide 250 Evohaler 120 mdi is not recommended for use for children less than four years of age. The dose may have to be adjusted by your doctor depending upon the condition of the child's disease and age.

Have a query?

FAQs

Seretide 250 Evohaler 120 mdi is used to treat and prevent respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).

Seretide 250 Evohaler 120 mdi consists of Salmeterol (bronchodilator) and Fluticasone (Fluticasone). Salmeterol relaxes the muscles in the airways, increasing airflow to the lungs. Fluticasone acts by blocking the production of prostaglandins (chemical messengers) that cause inflammation (swelling) of the airways.

Seretide 250 Evohaler 120 mdi should be cautiously administered under the doctor's guidance in seizures since bronchodilators like Salmeterol can cause central nervous system stimulation that can lead to other adverse conditions. Please consult your doctor before using Seretide 250 Evohaler 120 mdi if you have seizures.

Seretide 250 Evohaler 120 mdi contains bronchodilator (Fluticasone), which can cause a rise in blood glucose levels. Hence, therapy with Seretide 250 Evohaler 120 mdi is cautiously administered in patients with diabetes. Please monitor your blood glucose levels regularly and inform your doctor so that the dose can be adjusted accordingly.

Bronchodilator (Salmeterol) in Seretide 250 Evohaler 120 mdi may decrease the potassium levels in your body; therefore, it should be used with caution. Please consult your doctor before taking Seretide 250 Evohaler 120 mdi since low potassium levels can lead to other cardiovascular problems in patients with hypokalaemia.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Seretide 250 Evohaler 120 mdi is a combination medication used to treat and prevent respiratory disorders, such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Salmeterol and Fluticasone Propionate.

Seretide 250 Evohaler 120 mdi is a controller medication. It manages and prevents symptoms of asthma and chronic obstructive pulmonary disease (COPD) by keeping the airways open and reducing inflammation. It should be used regularly to be effective, and not to relieve sudden asthma attacks immediately.

Seretide 250 Evohaler 120 mdi contains a Fluticasone Propionate, which belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines), which helps reduce inflammation in the airways.

Yes, Seretide 250 Evohaler 120 mdi may increase heart rate due to the Salmeterol component, which is a long-acting beta2-adrenergic receptor agonist (LABA). This can lead to palpitations, tremors, and increased heart rate in some individuals. Try deep breathing exercises, relaxation techniques, staying hydrated, and avoiding caffeine and nicotine to manage an increased heart rate. If the increased heart rate persists or worsens, consult your healthcare provider for guidance.

Seretide 250 Evohaler 120 mdi may cause some common side effects, including nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle, or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of Seretide 250 Evohaler 120 mdi do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.

Seretide 250 Evohaler 120 mdi is not addictive. It is a very effective and useful medication for people suffering from breathing difficulties due to asthma and COPD.

Taking Seretide 250 Evohaler 120 mdi more frequently than prescribed will not make it more effective and can increase the risk of side effects. It is essential to use this medication exactly as directed by your doctor to manage your asthma or COPD effectively.

When using Seretide 250 Evohaler 120 mdi, following certain precautions is essential to ensure safe and effective use. Follow your doctor's instructions, and do not use it for sudden asthma attacks. Instead, use a rescue inhaler as your doctor advises. Additionally, rinse your mouth with water after inhaling to prevent fungal infections. Avoid asthma triggers, such as dust, pollen, or smoke, and store the inhaler correctly, out of the reach of children, pets, and extreme temperatures. Inform your doctor about other medications, supplements, or vitamins you're taking, and regularly monitor for side effects, such as increased heart rate, tremors, or mood changes.

Seretide 250 Evohaler 120 mdi should be stored below 30°C and kept away from moisture. Keep out of the reach of children. Always follow the storage instructions provided on the packaging or by your healthcare provider.

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India.
Other Info - SER0008

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