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  1. Home
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  3. Sestil-AD Tablet 10's

Sestil-AD Tablet 10's, Pack of 10 TABLETS
Sestil-AD Tablet 10's, Pack of 10 TABLETS
Sestil-AD Tablet 10's, Pack of 10 TABLETS
Sestil-AD Tablet 10's, Pack of 10 TABLETS
Sestil-AD Tablet 10's, Pack of 10 TABLETS
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Composition :

LOPERAMIDE-2MG

Manufacturer/Marketer :

Vanguard Therapeutics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Sestil-AD Tablet

Sestil-AD Tablet is an anti-diarrhoeal medicine used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies. Diarrhoea is a condition characterised by frequent bowel movements, resulting in loose, watery stools.

Sestil-AD Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Sestil-AD Tablet helps treat diarrhoea.

The most common side effects of Sestil-AD Tablet are headache, nausea, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Do not take Sestil-AD Tablet if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Sestil-AD Tablet may cause dizziness; therefore, do not drive unless you are alert. Keep the doctor informed about your health conditions and medications to help rule out any potential side effects or interactions.

Directions for Use

  • Sestil-AD Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Sestil-AD Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

Sestil-AD Tablet belongs to the class of anti-diarrhoeal medication used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and for reducing the volume of discharge from ileostomies. Sestil-AD Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Sestil-AD Tablet helps treat diarrhoea.

How Sestil-AD Tablet Works

Sestil-AD Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Sestil-AD Tablet helps treat diarrhoea.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sestil-AD Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Sestil-AD Tablet

Do not take more than the prescribed dose of Sestil-AD Tablet as it may cause an overdose. The symptoms of overdose include irregular heartbeat, increased heart rate, uncoordinated movements, muscle stiffness, drowsiness, weak breathing or difficulty urinating. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sestil-AD Tablet if you are allergic to any of its components, if you have severe diarrhoea after taking antibiotics, ulcerative colitis, constipation, or acute dysentery (characterised by blood in the stools). Inform the doctor if you have AIDS and your stomach becomes swollen, liver or kidney disease, diarrhoea for more than 48 hours, severe diarrhoea, a history of drug abuse, slow or irregular heartbeat, low level of potassium in your blood, or prolonged QT interval (a rare heart problem). Seek immediate medical attention if you experience any of the following symptoms while taking loperamide: fast, irregular, or pounding heartbeat; dizziness; lightheadedness; unresponsiveness; or fainting. Avoid exceeding the recommended dosage, as it may lead to serious heart problems.

Drug-Drug Interactions

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LoperamideMibefradil
Severe
LoperamideVerapamil
Severe

Drug-Drug Interactions

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LoperamideMibefradil
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with mibefradil may raise blood levels of Sestil-AD Tablet, you run the risk of developing major problems including abnormal heart rhythm. Other cardiac conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
Although there is a possible interaction between Sestil-AD Tablet and Mibefradil, you can take these medicines together if prescribed by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
LoperamideVerapamil
Severe
How does the drug interact with Sestil-AD Tablet:
Coadministration of Sestil-AD Tablet with verapamil may significantly raise the Sestil-AD Tablet levels in the blood, this can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with verapamil together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideIndinavir
Severe
How does the drug interact with Sestil-AD Tablet:
When taken in combination indinavir may significantly raise the Sestil-AD Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with indinavir together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideClopidogrel
Severe
How does the drug interact with Sestil-AD Tablet:
Taking Sestil-AD Tablet with clopidogrel may significantly increase the blood levels of Sestil-AD Tablet. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking clopidogrel with Sestil-AD Tablet may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
LoperamideBepridil
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with bepridil may raise Sestil-AD Tablet levels in the blood significantly, this might result in side effects like abnormal heart rhythm. Additional heart conditions, and electrolyte imbalances (e.g., magnesium or potassium loss from severe or prolonged diarrhoea or vomiting) may potentially increase your susceptibility.

How to manage the interaction:
Although taking Sestil-AD Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
LoperamideTacrolimus
Severe
How does the drug interact with Sestil-AD Tablet:
Taking tacrolimus with Sestil-AD Tablet may significantly increases the Sestil-AD Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with tacrolimus together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideAtazanavir
Severe
How does the drug interact with Sestil-AD Tablet:
When Sestil-AD Tablet is taken with atazanavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with atazanavir together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not exceed the dose and frequency or duration of use of Sestil-AD Tablet advised by the doctor. Do not stop using any medications without talking to a doctor.
LoperamidePapaverine
Severe
How does the drug interact with Sestil-AD Tablet:
Combining Sestil-AD Tablet with Papaverine can raise the chance of an abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet and Papaverine together can cause an interaction, it can be taken if your doctor has suggested it. however, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor right away. Do not stop using any medications without consulting a doctor.
LoperamideRanitidine bismuth citrate
Severe
How does the drug interact with Sestil-AD Tablet:
Co-administration of Sestil-AD Tablet with ranitidine bismuth citrate may raise blood levels of Sestil-AD Tablet, you run the risk of developing major problems including abnormal heart rhythm. Other heart conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
There may be a possibility of interaction between Sestil-AD Tablet and Ranitidine bismuth citrate, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
LoperamideFlibanserin
Severe
How does the drug interact with Sestil-AD Tablet:
When taken in combination flibanserin may significantly raise the Sestil-AD Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Sestil-AD Tablet with flibanserin together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to stay hydrated.
  • Include bland foods such as bananas, rice, apples, cream of wheat, soda crackers, farina, applesauce, and toast to avoid aggravating the digestive system.
  • Avoid eating foods such as milk, dairy products, spicy foods, processed foods, pork, veal, sardines, raw vegetables, rhubarb, onions, corn, citrus fruits, alcohol, pineapples, cherries, seeded berries, grapes, caffeinated and carbonated drinks.
  • Eat fibre-rich food such as whole grains, lentils, beans, broccoli, and peas.
  • Wash your hands properly after using the toilet to prevent infections.
  • Clean the toilets regularly with a disinfectant.
  • Wash your hands thoroughly before eating, while preparing or serving.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Sestil-AD Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid/limit alcohol consumption as it may increase the side effects of this medicine, such as dizziness and drowsiness.

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Pregnancy

Caution

Loperamide belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks. Please consult the doctor if you are pregnant.

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Breast Feeding

Unsafe

Small amounts of Loperamide may appear in human breast milk. Therefore, it is not recommended during breastfeeding.

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Driving

Caution

Sestil-AD Tablet may cause dizziness, tiredness or sleepiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Consult your doctor

No data is available in patients with liver impairment. Please consult the doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

No data is available in patients with renal impairment. Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Sestil-AD Tablet is contraindicated in children below 2 years due to the risk of heart and breathing problems. Please consult the doctor if you have any concerns regarding the usage of Sestil-AD Tablet in children.

Have a query?

FAQs

Sestil-AD Tablet is used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies.

Sestil-AD Tablet works by slowing down the movement of the bowel to decrease the number of bowel movements. It also helps lower the flow of fluids and electrolytes into the bowel.

Yes, diarrhoea may cause dehydration due to loss of fluid in stools. So, drink plenty of fluids/water to replace lost fluids due to diarrhoea. Talk to your doctor about rehydration therapy to replace lost salts.

Do not exceed the recommended dosage, as it may cause serious or life-threatening changes in your heart rhythm. Avoid taking a larger dose, taking it for a longer period of time, or taking it more often than prescribed by your doctor.

No, Sestil-AD Tablet is not an antibiotic. It contains loperamide, which is an anti-diarrheal medication. Loperamide works by slowing down an overactive bowel and allowing the body to absorb water and salts usually lost in diarrhoea.

The duration of taking Sestil-AD Tablet depends on the severity of your diarrhoea and your doctor's advice. Typically, it is taken for a short period or as directed by your doctor for chronic diarrhoea or inflammatory bowel disease. It's essential to follow your doctor's instructions and not exceed the recommended duration or dosage, as taking Sestil-AD Tablet for longer than prescribed can lead to dependence or other side effects.

The effect of a single dose of Sestil-AD Tablet typically lasts for 4 to 6 hours. However, this duration can vary depending on individual factors, such as the severity of diarrhoea, individual metabolism, and the presence of other medications or medical conditions. If symptoms persist or worsen, it's important to consult a healthcare provider for further guidance. Additionally, do not exceed the recommended dose or take Loperamide for longer than 2 days without medical advice.

Take Sestil-AD Tablet for up to 2 days to manage acute diarrhoea. If symptoms persist or worsen, consult your healthcare provider. Do not take longer than recommended to avoid dependence and side effects.

Do not take Sestil-AD Tablet with painkillers on your own. Only take it if recommended by your doctor. Combining medications without medical advice can be harmful. Always consult your healthcare provider before taking Sestil-AD Tablet with painkillers or any other medications.

You can take probiotics with Sestil-AD Tablet , but it's best to check with your doctor first. Probiotics can help alleviate diarrhoea and restore the balance of gut bacteria. Taking them with Sestil-AD Tablet may make it work better and reduce side effects. However, consult your doctor to ensure safe and effective use, especially if you have a weakened immune system or take other medications.

Diarrhea is a common condition characterized by frequent bowel movements, loose or watery stools, and an urgent need to have a bowel movement. Various factors, including viral or bacterial infections, food intolerance or allergies, medications, digestive disorders, infections, and hormonal changes, can cause it. Suppose you experience persistent, severe, or bloody diarrhoea. In that case, seeking medical attention to determine the underlying cause and receive appropriate treatment is essential.

Take Sestil-AD Tablet when you have acute diarrhoea or irritable bowel syndrome (IBS) with frequent diarrhoea. However, take it only if your doctor recommends it, for a short period (up to 2 days), and only if your symptoms are not severe. Also, do not take it if you have bloody stools, fever, or abdominal pain. Always follow the recommended dosage and consult your healthcare provider if symptoms persist or worsen.

A doctor will direct the dose of Sestil-AD Tablet for adults, as it may vary depending on individual circumstances and medical history. Your doctor may adjust the dose based on your specific needs and response to treatment. Always follow your doctor's instructions and consult with them if you have any questions or concerns.

Yes, Sestil-AD Tablet can be used to treat motions (diarrhoea). It is an anti-diarrheal medication that works by slowing down bowel movements and increasing the absorption of water and electrolytes from the intestines. This helps to firm up stool and reduce the frequency of bowel movements. However, it's important to note that Sestil-AD Tablet should only be used under the guidance of a healthcare professional, especially if you have underlying medical conditions, are taking other medications, or are experiencing severe or persistent diarrhoea.

Sestil-AD Tablet typically starts to work within 1-2 hours after taking it. It may take up to 4-6 hours to reach its full effect. However, this may vary depending on individual factors, such as the severity of diarrhoea and individual metabolism.

Sestil-AD Tablet typically contains the active ingredient Loperamide Hydrochloride, an anti-diarrheal medication.

Sestil-AD Tablet containing Loperamide Hydrochloride is generally considered safe when used as directed. However, as with all medications, it may cause side effects and interact with other medicines. To ensure safe use, follow the recommended dosage, inform your doctor about your medical history, and monitor for side effects.

Sestil-AD Tablet can be used to treat diarrhoea and abdominal pain associated with Irritable Bowel Syndrome (IBS), but only under the guidance of a healthcare professional. While it can help manage symptoms, it's important to note that Loperamide may not address the underlying causes of IBS, and long-term use should be avoided. Your healthcare provider may also recommend other treatments or lifestyle changes to manage IBS symptoms.

Do not take Sestil-AD Tablet with any other medication, including antibiotics, paracetamol, ibuprofen, omeprazole, ciprofloxacin, desmopressin, ritonavir, quinidine, or cotrimoxazole, unless advised by your doctor. Always consult your healthcare provider before combining medications to ensure safe and effective treatment.

Sestil-AD Tablet can help with diarrhoea and stomach cramps during opiate withdrawal, but it's not a treatment for withdrawal itself. It can manage some symptoms, but it's important to remember that it doesn't address the underlying issues and shouldn't replace medically supervised treatment. Consult a healthcare professional for proper guidance and support during opiate withdrawal.

Sestil-AD Tablet carries a low risk of addiction when used as directed by a healthcare professional to treat diarrhoea. However, taking high doses or using it for extended periods can increase the risk of habit formation and addiction. Individuals with a history of substance abuse or addiction should exercise caution.

Sestil-AD Tablet can help alleviate diarrhoea caused by stomach flu, nausea, and some stomach cramps associated with diarrhoea. However, it's important to note that Sestil-AD Tablet is not recommended for bloody diarrhoea, fever, gas, or rotavirus infections. In fact, anti-diarrheal medications like Loperamide are not recommended for rotavirus infections. Always consult a healthcare professional for proper diagnosis and treatment.

Sestil-AD Tablet and cimetidine can be taken together. Cimetidine is an antacid and histamine-2 (H2) blocker that may not significantly interact with Loperamide. However, it's always best to consult your healthcare provider or pharmacist to ensure safe and effective treatment before taking any medications together.

Take Sestil-AD Tablet only as directed by your doctor, based on your individual medical needs and condition. Follow the recommended dosage and frequency, and do not exceed the maximum dose prescribed. Always consult your doctor if you have any questions or concerns.

Yes, you can take Sestil-AD Tablet for loose motion (diarrhoea). Sestil-AD Tablet is commonly used to treat diarrhoea and reduce the frequency of loose stools. However, it's essential to consult your doctor before taking Loperamide, especially if you have any of the following: bloody or watery diarrhoea, fever, abdominal pain or cramping, or underlying medical conditions like inflammatory bowel disease (IBD). Remember, Sestil-AD Tablet only treats symptoms, not the underlying cause of diarrhea. Your doctor will recommend the most suitable treatment based on your individual needs.

The most common side effects of Sestil-AD Tablet are headache, nausea, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Flat No 102, Pancom Business Centre, Vinod Chambers, Ameerpet, Hyderabad - 500016
Other Info - SES0001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 2, 2025 | 10:57 AM IST

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Reference

  1. https://www.ditenate.al/en/products/pharmacy/digestive/diarrhea/loperamide-2-mg-20-tablets
  2. https://www.medicines.org.uk/emc/files/pil.12451.pdf
  3. https://medlineplus.gov/druginfo/meds/a682280.html
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017694s052lbl.pdf
  5. https://www.drugs.com/loperamide.html

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