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Sevfirst-400 Tablet 10's

Sevfirst-400 Tablet 10's

Prescription drug
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Synonym

SEVELAMER CARBONATE

Composition

SEVELAMER-400MG

Manufacturer/Marketer

Rennew Biotech

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

About Sevfirst-400 Tablet 10's

Sevfirst-400 Tablet 10's belongs to a group of medications called phosphate binder (which decreases the level of phosphate in the body). It is primarily used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Sevfirst-400 Tablet 10's contains sevelamer that works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes.

Take Sevfirst-400 Tablet 10's exactly as directed by your doctor. The most common side effects of Sevfirst-400 Tablet 10's are vomiting, upper abdominal pain, nausea, diarrhoea, stomach ache, indigestion, and flatulence. However, if the side effects persist, contact your doctor.

The use of Sevfirst-400 Tablet 10's is restricted in persons with a known history of allergic to any of the ingredients present in this medicine, have low levels of phosphate in their blood, and have a bowel obstruction. Sevfirst-400 Tablet 10's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevfirst-400 Tablet 10's. Tell your doctor if you are facing swallowing problems, motility (movement) in your stomach and bowel, being sick frequently, active inflammation of the bowel,  have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. If you are pregnant or breastfeeding, please consult your doctor before taking Sevfirst-400 Tablet 10's.

Uses of Sevfirst-400 Tablet 10's

Treatment of Hyperphosphatemia (high phosphorus level in blood).

Medicinal Benefits

Sevfirst-400 Tablet 10's belongs to a group of medications called phosphate binder, which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes. Sevfirst-400 Tablet 10's controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease.

Directions for Use

Tablet: Sevfirst-400 Tablet 10's should be taken as prescribed by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Take Sevfirst-400 Tablet 10's as prescribed by the doctor. Before taking, disperse the tablet in the prescribed amount of water, mix well and then swallow it. Do not crush, chew or swallow as a whole.Powder/granules: Firstly, shake the container and open the cap. Add the powder of the packet to a cup containing two teaspoonfuls (30 ml) of water. Mix well and make your child drink within 30 minutes. It is advised not to give more than the prescribed dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sevfirst-400 Tablet 10's

  • Headache
  • Diarrhoea
  • Stomach upset
  • Constipation

Drug Warnings

You should avoid taking Sevfirst-400 Tablet 10's if you are allergic to Sevfirst-400 Tablet 10's. Speak to your doctor if you have swallowing disorders, digestive tract surgery, severe constipation, have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. It should be used with caution if you are pregnant or planning to become pregnant. Sevfirst-400 Tablet 10's should not be recommended for breastfeeding mothers as it passes into breast milk. Avoid alcohol consumption while taking Sevfirst-400 Tablet 10's as it might cause unpleasant side effects. The safety and effectiveness of children under six years of age have not been established, so a Sevfirst-400 Tablet 10's should not be given to them. Sevfirst-400 Tablet 10's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Sevfirst-400 Tablet 10's. Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is advised while taking Sevfirst-400 Tablet 10's.

Drug Interactions

Drug-Drug Interactions: Sevfirst-400 Tablet 10's interacts with antibiotics (ciprofloxacin), immunosuppressive agents (mycophenolate), thyroid medications  (levothyroxine), and medication used to treat bladder cancer (erdafitinib).

Drug-Food Interactions: Avoid taking high-phosphate additives and alcohol as this makes it harder for your body to absorb Sevfirst-400 Tablet 10's and increases side effects. Using Sevfirst-400 Tablet 10's together with multivitamins with minerals may decrease the effects of multivitamins with minerals. So, Multivitamins with minerals should be administered at least 4 hours before Sevfirst-400 Tablet 10's.

Drug-Disease Interactions: The use of Sevfirst-400 Tablet 10's is restricted in people with hypophosphatemia (low phosphate level in blood), bowel obstruction and perforation, and severe liver disease.

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • MYCOPHENOLATE SODIUM
  • LEVOTHYROXINE SODIUM
  • ERDAFITINIB

Habit Forming

No

Diet & Lifestyle Advise

  • Take fresh fruits, vegetables, rice, milk, un-enriched corn and rice cereals, and soda without phosphate additives in your regular diet.
  • Avoid or limit high phosphorus addictive foods (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
  •  Avoid intake of alcoholic beverages with Sevfirst-400 Tablet 10's as it can make you dehydrated and may increase the side effects. 
  • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate and will help you overcome some.
  • Sevfirst-400 Tablet 10's is preferably taken with meals as it can bind to dietary phosphate and prevent its absorption into the bloodstream. Drink it with a full glass of water.
  • Do not stop taking the Sevfirst-400 Tablet 10's dose until your doctor says so.
  • Do not use Sevfirst-400 Tablet 10's if you have a history of bowel obstruction.

Special Advise

  • Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is recommended while taking Sevfirst-400 Tablet 10's.

Disease/Condition Glossary

Hyperphosphatemia: Hyperphosphatemia is defined as an increased phosphate level in the blood. This condition is often a complication of chronic kidney disease. Phosphate is an important electrolyte. It strengthens your bones and teeth and produces energy.  When phosphate levels increase in the blood due to kidney impairment (the kidney does not remove extra phosphate out of the body), this can cause muscle problems and increase the risk of weak bones, heart attacks, and strokes. It is more common in people with chronic kidney disease and people on dialysis. Symptoms may include itchy skin, red eyes, bone pain, and fractures.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Sevfirst-400 Tablet 10's to avoid unpleasant side effects.

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Pregnancy

Caution

Sevfirst-400 Tablet 10's is Category C pregnancy medicine. Please consult your doctor if you have any concerns; your doctor will prescribe you Sevfirst-400 Tablet 10's only if the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Sevfirst-400 Tablet 10's has not been established in breastfeeding women. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether the Sevfirst-400 Tablet 10's can be given to breastfeeding mothers or not.

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Driving

Safe if prescribed

Sevfirst-400 Tablet 10's has no or negligible influence on the ability to drive or operate any machinery.

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Liver

Caution

Sevfirst-400 Tablet 10's should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

Dose adjustment may be needed. Sevfirst-400 Tablet 10's should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

For children, SEVELAMER is available in pouches for oral suspension. Please consult your paediatrician for further information. The paediatrician will decide the dose of this medicine.

Country of origin

India

Manufacturer/Marketer address

16-2/60, 1st Floor, Thaneer Thurai Street, Vaver Khan Palayam, PO-Uthamapalayam, Theni Dist., Tamil Nadu-626533, India.
Other Info -

FAQs

Sevfirst-400 Tablet 10's is in a class of medications called phosphate binders. Sevfirst-400 Tablet 10's works by holding onto phosphate from the diet so that it can pass out of your body.
No, ciprofloxacin may interfere with the working of Sevfirst-400 Tablet 10's; therefore, it should not be taken simultaneously as Sevfirst-400 Tablet 10's.
Sevfirst-400 Tablet 10's works by holding onto phosphate from the food so that it can pass out of your body. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels.
Yes, constipation is the common side effect of Sevfirst-400 Tablet 10's, though it does not occur in everyone. Please consult your doctor if the side effect becomes severe and disturb you.
Yes, serum phosphate levels should be monitored regularly while you are taking Sevfirst-400 Tablet 10's. The use of Sevfirst-400 Tablet 10's may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.
No, Sevfirst-400 Tablet 10's is a class of medications called phosphate binder used to control the phosphate level in blood. If you stop taking Sevfirst-400 Tablet 10's, your phosphate levels may elevate again. Please consult your doctor.

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