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compositionComposition:SEVOFLURANE-250ML
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Prescription Medicine
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Sevura 250Ml Inhaltion is an anaesthetic agent used for induction and maintenance of general anaesthesia during surgical procedures. Anesthesia is a medical procedure that reduces pain and discomfort during surgical or medical procedures. Sevura 250Ml Inhaltion contains 'Sevoflurane', an inhaled, volatile anaesthetic. It acts on the brain and causes unconsciousness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SEVOFLURANE-250ML

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sevura 250Ml Inhaltion

Sevura 250Ml Inhaltion is an inhalation general anesthetic used to start and maintain deep sleep during surgical procedures. It helps ensure that you remain completely unconscious, relaxed, and free of pain while undergoing a medical operation. This medicine is commonly used for both adults and children in hospital environments.

Because this medication is used strictly for surgical procedures, it is not something you take on a regular daily schedule at home. It is inhaled through a breathing mask or a special tube during your surgery, administered by a trained anesthesia specialist. Before receiving this medicine, patients are typically required to fast, meaning you must not eat or drink for several hours before your surgery to ensure your safety.

After waking up, some people may experience common side effects like shivering, nausea, vomiting, or a cough. If you experience severe symptoms like an extremely high fever, muscle stiffness, or yellowing of your skin or eyes after surgery, tell your healthcare team immediately, as these can be signs of rare but serious complications.

Do not take this if you or anyone in your family has ever had a severe, life-threatening reaction to anesthesia called malignant hyperthermia. You should also tell your doctor if you have liver problems, kidney disease, or a heart condition before undergoing anesthesia.

Tell your doctor about all other medicines you are taking, as certain heart and blood pressure drugs can interact with Sevura 250Ml Inhaltion. It is also important to tell your medical team if you are pregnant, breastfeeding, or if the patient is an older adult, so they can take extra precautions during your care.

Uses of Sevura 250Ml Inhaltion

Your doctor may prescribe Sevura 250Ml Inhaltion to help manage the following conditions:

  • Induction of general anesthesia: Sevura 250Ml Inhaltion helps patients fall into a deep, pain-free sleep quickly and smoothly before a surgical operation begins.
  • Maintenance of general anesthesia: It keeps patients in a safe, controlled state of unconsciousness throughout the entire duration of the surgery.

Key Benefits

Sevura 250Ml Inhaltion offers several clinical benefits that help make your surgical experience safer and more comfortable:

  • Rapid onset of sleep: It works quickly when inhaled, allowing you to drift into a deep sleep without delay or feelings of anxiety.
  • Smooth and easy recovery: The medicine clears out of your body rapidly once the inhalation is stopped, allowing you to wake up faster with less lingering grogginess.
  • Gentle on the airways: It has a pleasant, non-irritating sweet smell, which makes it much easier to inhale through a mask. This is especially helpful for children who may feel nervous about needles or strong chemical smells.
  • Precise control: Your anesthesia team can easily adjust the amount of medicine you breathe in, ensuring you stay at the exact level of sleep required for your safety.
Side effects of Sevura 250Ml Inhaltion
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • To assist warm the body, sip herbal teas like peppermint or ginger.
  • To provide warmth to the body, use heating pads or hot water bottles.
  • Avoid lying or sitting on chilled surfaces as this can make shivering worse.
  • To increase body temperature, take warm showers or baths.

Directions for Use

  • Sevura 250Ml Inhaltion will be administered by a trained anesthesiologist.
  • Do not self-administer.

How Sevura 250Ml Inhaltion Works

Sevura 250Ml Inhaltion contains the active inhalation medicine Sevura 250Ml Inhaltion. When you inhale the vapour of this medicine, it travels through your lungs and quickly enters your bloodstream, which carries it directly to your brain. Once in the brain, it temporarily slows down the activity of your central nervous system. It interrupts the communication between your nerve cells, preventing your brain from receiving pain signals or processing sensory information. This state of controlled, temporary unconsciousness ensures you do not feel, hear, or remember anything during your surgical procedure. Once the delivery of the vapour is stopped, the medicine is exhaled out of your body through your lungs, allowing you to wake up naturally.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Sevura 250Ml Inhaltion.

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Pregnancy

Caution

Sevura 250Ml Inhaltion should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor before receiving Sevura 250Ml Inhaltion if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Breastfeeding should be discontinued for 48 hours following Sevoflurane treatment, and any milk produced during this time should be discarded.

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Driving

Unsafe

Patients should not drive or operate heavy machinery for at least 24 hours after receiving Sevoflurane.

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Liver

Caution

Caution should be exercised while using Sevura 250Ml Inhaltion in patients with liver impairment. So, inform your doctor before receiving Sevura 250Ml Inhaltion if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Caution should be exercised while using Sevura 250Ml Inhaltion in patients with Kidney impairment. So, inform your doctor before receiving Sevura 250Ml Inhaltion if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Safe if prescribed

Sevura 250Ml Inhaltion is generally safe for heart patients when used only under medical supervision. However, it is important to consult your doctor if you have any concerns or underlying conditions.

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Geriatrics

Consult your doctor

Sevura 250Ml Inhaltion is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Sevura 250Ml Inhaltion

An overdose is highly unlikely because your breathing and vital signs are continuously monitored by an anesthesia specialist during your surgery. If the level of medicine becomes too high, the specialist will immediately adjust the vaporiser to reduce the dose and support your breathing. If you have concerns about your recovery, talk to your doctor or pharmacist.

Diet & Lifestyle Advise

  • Follow fasting rules strictly: Do not eat or drink anything (including water, chewing gum, or mints) for the specified hours before your surgery to prevent dangerous complications while asleep.
  • Avoid alcohol and smoking: Refrain from drinking alcohol and smoking for at least 24 hours before your procedure, as they can affect how your heart and lungs respond to anesthesia.
  • Arrange a safe ride home: Make sure a responsible adult is available to drive you home after your surgery, as you will still feel sleepy and your coordination will be temporarily impaired.
  • Plan for rest: Keep your schedule clear of strenuous activities, major decisions, or operating machinery for at least 24 hours post-surgery to allow the medicine to fully clear from your system.
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How Soon It Starts Working

The time required for Sevura 250Ml Inhaltion to start to work: Sevura 250Ml Inhaltion ideally shows its action within 2 minutes after administration. The time for which the effects of Sevura 250Ml Inhaltion last: The effect of Sevura 250Ml Inhaltion lasts for 4 to 14 minutes.

What if you forget to take Sevura 250Ml Inhaltion

Since Sevura 250Ml Inhaltion is only given by a healthcare professional in a hospital or clinical setting during a scheduled surgery, it is not possible for you to miss a dose at home.

Storage

• Sevura 250Ml Inhaltion is stored and maintained entirely within a hospital or clinical environment, It is kept at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a secure area.

Drug Warnings

  • Anesthesia Reaction History: Always tell your surgical team if you or a family member has ever had a dangerous reaction to anesthesia, particularly high fevers or liver damage.
  • Post-Anesthesia Activity Restriction: Do not drive, cook, or operate any machinery for at least 24 hours after waking up from Sevura 250Ml Inhaltion, as your coordination and reflexes will be slow.
  • Medication Disclosure Before Surgery: Provide your complete list of medications, including herbal supplements and over-the-counter drugs, to your anesthesiologist before your scheduled surgery.
  • Common Post-Anesthesia Effects: Expect to feel groggy, cold, or slightly nauseous immediately after waking up; your healthcare team will monitor you and provide medication to help you feel better.
  • Avoid Important Decisions Post-Surgery: Avoid signing legal documents or making major life decisions on the day of your surgery, as your judgment may be temporarily clouded.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood pressure medications (like beta-blockers or calcium channel blockers): May cause your blood pressure or heart rate to drop too low when combined with Sevura 250Ml Inhaltion.
  • Epinephrine or decongestants: May increase the risk of developing irregular heart rhythms during surgery.
  • Opioids and sedatives (like benzodiazepines): May increase the depth of sleep and slow your breathing, requiring the anesthesia team to carefully adjust the dosage.
SevofluranePhenylephrine
Critical
SevofluraneSelegiline
Severe

Drug-Drug Interactions

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SevofluranePhenylephrine
Critical
How does the drug interact with Sevura 250Ml Inhaltion:
Co-administration of Phenylephrine with Sevura 250Ml Inhaltion can increase the levels of phenylephrine and lead to side effects.

How to manage the interaction:
Taking Phenylephrine with Sevura 250Ml Inhaltion is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
SevofluraneSelegiline
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
Co-administration of Sevura 250Ml Inhaltion with Selegiline can lead to fluctuations in blood pressure.

How to manage the interaction:
Although taking Selegiline and Sevura 250Ml Inhaltion together can cause an interaction, it can be taken if a doctor has suggested it. In case you experience any symptoms like lightheadedness, blurred vision, fainting, severe headache, numbness in hands and legs (especially towards one side of the body), or palpitations, consult a doctor. Do not stop using any medications without talking to a doctor.
SevofluraneTirzepatide
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
This raises the possibility of regurgitation while under anesthesia, leading to the inhalation of stomach contents into the lungs, which can result in lung inflammation or damage.

How to manage the interaction:
Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interfere with the safety of your anesthesia. It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.
SevofluraneSotalol
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
Using sotalol together with Sevura 250Ml Inhaltion can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Sevura 250Ml Inhaltion, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
SevofluraneFentanyl
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
Combining Fentanyl with Sevura 250Ml Inhaltion can increase the risk of CNS depression.

How to manage the interaction:
Although there is a possible interaction between Sevura 250Ml Inhaltion and Fentanyl, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
SevofluraneCeritinib
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
Taking Sevura 250Ml Inhaltion with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Sevura 250Ml Inhaltion together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SevofluraneHydroxychloroquine
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
The combined use of Sevura 250Ml Inhaltion and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Sevura 250Ml Inhaltion and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
SevofluraneChloroquine
Severe
How does the drug interact with Sevura 250Ml Inhaltion:
Using chloroquine together with Sevura 250Ml Inhaltion can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Sevura 250Ml Inhaltion together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Sevura 250Ml Inhaltion when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[GENERAL ANESTHETICS]

FAQs

Sevura 250Ml Inhaltion is an inhalation general anaesthetic used to induce and maintain general anaesthesia during surgical procedures. It helps make you unconscious and prevents you from feeling pain during surgery. Talk to your doctor if you have questions about your upcoming surgery.
Sevura 250Ml Inhaltion contains Sevoflurane, which is an inhaled general anaesthetic. It acts on the brain and causes unconsciousness.
Sevura 250Ml Inhaltion may affect your heart rhythm. Disturbances of the heart rhythm are very common. Your anaesthetist will quickly deal with any problems that arise during your operation.
Caution should be exercised when administering general anaesthesia, including sevoflurane, to patients with mitochondrial disorders. Tell your doctor and anaesthetist about any medical conditions you have before receiving Sevura 250Ml Inhaltion, so they can determine the most appropriate anaesthetic for you.
Yes, it is widely used in pediatric surgeries because it has a non-irritating smell and allows children to drift off smoothly without requiring an initial needle stick. Talk to your doctor to learn more about pediatric anesthesia safety.
No, you must not drive or operate machinery for at least 24 hours after receiving Sevura 250Ml Inhaltion, as it takes time for your reflexes and coordination to fully return to normal. Talk to your doctor or pharmacist about post-operative care.
The most common side effects are shivering, nausea, vomiting, coughing, and drowsiness. Talk to your doctor if these symptoms persist or become uncomfortable.
Malignant hyperthermia is a rare, life-threatening genetic reaction to certain anesthetics that causes a rapid spike in body temperature and muscle rigidity. If you have a family history of this condition, you must tell your medical team so they can use alternative medications. Talk to your doctor for more safety details.
Yes, you must follow strict fasting instructions (no food or drinks) before your surgery to prevent inhalation of stomach contents into your lungs while under anesthesia. Talk to your doctor for specific pre-surgery instructions.
Most of the medicine is quickly exhaled out through your lungs once the vaporiser is turned off, which is why patients wake up relatively fast. Talk to your doctor if you want to know more about what to expect after waking up.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.833 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. DrugBank Online. Db01236 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 020478S016Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Sevoflurane Sevoflurane. 1995. [Accessed on 05 Apr. 2019]Check here
  5. Miller AL, Theodore D, Widrich J. Inhalational Anesthetic. National Institute of Health, National Library of Medicine, National Centre for Biotechnology Information. 2023. [Accessed on 2nd September 2024]Check here
  6. Piramal Critical Care B.V. Electronic Medicines Compendium (EMC). [Revised in August 2023] [Accessed on 2nd September 2024]Check here
  7. Chanelle Medical Unlimited Company. Health Products Regulatory Authority (HPRA). [Revised in June 2022] [Accessed on 2nd September 2024]Check here

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - SEV0074
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