apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Sibofix Suspension 60 ml

Sibofix Suspension 60 ml, Pack of 1 Suspension
Offers on medicine orders
All offers
axis icici
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sibofix Suspension is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). It contains Rifaximin, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria. Thus, it helps in relieving abdominal pain and diarrhoea. In some cases, you may experience common side effects such as headaches, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid buildup in the abdomen), and increased liver enzymes (ALT). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Also Explore

Momverse
Ask Apollo
insurance

Composition :

RIFAXIMIN-100MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sibofix Suspension

Sibofix Suspension used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). Traveller’s diarrhoea is an infection in which there is a passage of unformed stools. Hepatic encephalopathy causes loss of brain function when a damaged liver is unable to remove toxins from the blood. Irritable bowel syndrome is a condition which affects the large intestine. 

Sibofix Suspension contains ‘Rifaximin’, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria.  Thus, Sibofix Suspension helps in relieving abdominal pain and diarrhoea. Sibofix Suspension should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E.coli).

Take Sibofix Suspension with or without food. In some cases, you may experience common side effects such as headaches, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid buildup in the abdomen), and increased liver enzymes (ALT). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Sibofix Suspension, please inform your doctor if you have any allergies (to any antibiotic), kidney or liver problems. Do not take Sibofix Suspension for more than 3 days unless your doctor prescribes it; if you don't experience symptomatic improvement, consult your doctor. Avoid taking Sibofix Suspension if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you an alternative medicine. Sibofix Suspension is not recommended for children as efficacy and safety have not been established. Inform your doctor about all the medications you are taking and your health condition to help rule out any unpleasant side effects.

Uses of Sibofix Suspension

Sibofix Suspension is used in the treatment of travelles diarrhoea, liver encephalopathy, and irritable bowel syndrome due to diarrhoea. The detailed uses of Sibofix Suspension are as follows:
• Diarrhea in Travelers: Sibofix Suspension is frequently used to treat patients' diarrhea brought on by non-invasive strains of Escherichia coli when they are visiting places with contaminated food or water.
• Irritable Bowel Syndrome (IBS): By treating intestinal bacterial overgrowth, Sibofix Suspension can help reduce IBS symptoms, especially those with diarrhoea as the predominant symptom.
• Simple Infections: Sibofix Suspension works well for treating simple gastrointestinal infections that might not be improving with other antibiotics.
• Complications Associated with Liver Disease: By reducing the amount of ammonia-producing bacteria in the gut, this medication helps treat hepatic encephalopathy. This condition can develop in people with liver disease.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Sibofix Suspension belongs to the group of medicines called antibiotics used to treat infectious travellers diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome (IBS). Sibofix Suspension is used to treat traveller’s diarrhoea caused by non-invasive strains of E.coli. Sibofix Suspension is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and anaerobic bacteria, and ammonia-producing bacteria. Sibofix Suspension is a gastrointestinal-selective antibiotic with a broad spectrum of antimicrobial activity. Sibofix Suspension is bactericidal in nature and works by killing the bacteria that cause infections. Thus, it helps in treating and preventing the spread of infections.

How Sibofix Suspension Works

Sibofix Suspension contains ‘Rifaximin’, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria.  Thus, Sibofix Suspension helps in relieving abdominal pain and diarrhoea. Sibofix Suspension should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E.coli).

Storage

Store in a cool and dry place away from sunlight
Side effects of Sibofix Suspension 60 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Sibofix Suspension

Do not take more than the prescribed dose of Sibofix Suspension as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sibofix Suspension if you are allergic to any of its contents, if you have a fever, blood in stools, passed 8 or more unformed stools in the last 24 hours, constipation, vomiting, and abdominal pain caused by blockage of the bowel. Talk to your doctor if your condition does not improve, symptoms continue or re-appear even after taking Sibofix Suspension for 3 days. Do not take Sibofix Suspension for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor. Avoid taking Sibofix Suspension if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you with alternate medicine. Sibofix Suspension is not recommended for children below 12 years of age as the efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. Patients with liver complications should avoid taking Sibofix Suspension or consult a doctor before using Sibofix Suspension.

Drug-Drug Interactions

verifiedApollotooltip
RifaximinCholera, live attenuated
Severe

Drug-Drug Interactions

Login/Sign Up

RifaximinCholera, live attenuated
Severe
How does the drug interact with Sibofix Suspension 60 ml:
Coadministration of cholera vaccine with Sibofix Suspension 60 ml may reduce the effect of the cholera vaccine.

How to manage the interaction:
Taking Rfaximine and Cholera, live attenuated together can result in an interaction, but it can be taken together if prescribed by a doctor. It is recommended to take the cholera vaccine at least 14 days following the last dosage of Sibofix Suspension 60 ml. Do not discontinue any medicine without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid the usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Sibofix Suspension Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Caution

Please consult your doctor as it is not known whether alcohol affects the working of Sibofix Suspension. However, you are advised to limit or avoid alcohol consumption to prevent unpleasant side-effects.

bannner image

Pregnancy

Caution

It is not recommended to take Sibofix Suspension while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Sibofix Suspension can be given to pregnant women or not.

bannner image

Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Sibofix Suspension can be given to breastfeeding mothers or not.

bannner image

Driving

Safe if prescribed

Sibofix Suspension does not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease before taking Sibofix Suspension.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Sibofix Suspension.

bannner image

Children

Unsafe

Sibofix Suspension is not recommended for children as the efficacy and safety have not been established.

Have a query?

FAQs

Sibofix Suspension is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D).

Sibofix Suspension is bactericidal in nature and works by killing the harmful bacteria that cause infections in the gut or intestine like E coli bacteria. Thereby, helps in treating/preventing the spread of infections and diarrhoea with abdominal pain.

It is recommended to complete the course of Sibofix Suspension even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Do not take Sibofix Suspension on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Take Sibofix Suspension only if prescribed by a doctor.

Sibofix Suspension may affect blood tests and liver function tests with increased liver enzymes. Inform the person or doctor before performing the tests that you are taking Sibofix Suspension.

For treating traveller's diarrhoea, Sibofix Suspension is generally prescribed for 3 days. For irritable bowel syndrome, Sibofix Suspension is prescribed for 14 days. However, it is better to take Sibofix Suspension only as prescribed by your doctor.

No, Sibofix Suspension may affect the activity and working of warfarin when taken together. So tell your doctor before using Sibofix Suspension that you are taking a blood thinner (warfarin). Your doctor might adjust the dose of warfarin to maintain the proper blood-thinning effect and prevent drug interaction.

Do not take Sibofix Suspension for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor.

Sibofix Suspension should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E. coli).

Take Sibofix Suspension exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.

Sibofix Suspension contains Rifaximin used to treat infectious traveller’s diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome.

Side effects of Sibofix Suspension include headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Talk to your doctor if you experience these side effects persistently.

Sibofix Suspension is an antimycobacterial which works by killing the bacteria that cause infection.

Sibofix Suspension can be taken with or without food.

Sibofix Suspension decreases the symptoms in case of liver disease by killing harmful bacteria in the gut. Thereby it helps lower the possibility of toxins.

Sibofix Suspension may not cause weight gain. Maintain proper weight by eating healthy and doing exercise. Consult the doctor if you notice changes in your weight.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy\'s Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA.
Other Info - SIB0023

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 25, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.xifaxan.com/about-xifaxan-ibsd
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021361s023lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a604027.html
  4. https://www.drugs.com/mtm/rifaximin.html
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737517/
whatsapp Floating Button