Signoflam Tablet 10's belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Signoflam Tablet 10's is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.
Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.
You can take Signoflam Tablet 10's with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Most of the side effects of Signoflam Tablet 10's do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Do not take Signoflam Tablet 10's if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.
Uses of Signoflam Tablet 10's
Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.
Signoflam Tablet 10's consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.
Directions for Use
Tablet: Swallow it as a whole with water; do not crush, break or chew it.
Store in a cool and dry place away from sunlight
Side Effects of Signoflam Tablet 10's
Loss of appetite
Consumption of alcohol should be avoided during the treatment with Signoflam Tablet 10's as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Signoflam Tablet 10's on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Signoflam Tablet 10's. Use with caution in pregnancy and breastfeeding. Do not self-administer Signoflam Tablet 10's if you are pregnant or are nursing.
Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), and blood clotting agents (warfarin) should not be taken with Signoflam Tablet 10's as they may interact.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: Inform your doctor if you have peptic ulcer, gastric bleeding, severe heart failure, and high blood pressure before taking Signoflam Tablet 10's.
Drug-Drug Interactions Checker List
Diet & Lifestyle Advise
Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.
Paracetamol is a component of Signoflam Tablet 10's which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
Although Signoflam Tablet 10's provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.
Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage of the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissues (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.
You are recommended not to consume alcohol along with Signoflam Tablet 10's to avoid unpleasant side-effects.
Signoflam Tablet 10's to be taken with caution, specially if you are pregnant. Your doctor may adjust your dose depending upon your conditions, if he/she feels the benefits over weigh the risks.
Only consume Signoflam Tablet 10's if it has been prescribed by a doctor as the safety data in nursing mothers is lacking. Inform your doctor if you are breastfeeding.
Signoflam Tablet 10's may affect driving as it causes dizziness.
Signoflam Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.
Signoflam Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Signoflam Tablet 10's should not be given to children without prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and severity of condition.
Is it safe to take Signoflam Tablet 10's?
Yes, in most of the patients it is safe to take Signoflam Tablet 10's but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.
In what conditions Signoflam Tablet 10's is contraindicated?
Signoflam Tablet 10's when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,
What is rheumatoid arthritis?
A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.
What is ankylosing spondylitis?
Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.
Can I take Signoflam Tablet 10's for stomach pain?
No. Signoflam Tablet 10's is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.
Can Signoflam Tablet 10's can be taken with alcohol?
Taking excessive alcohol with Signoflam Tablet 10's can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Signoflam Tablet 10's.
Can I take Signoflam Tablet 10's with other pain killers?
Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.
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