Silectone 25 Tablet is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. Oedema is associated with pulmonary hypertension (high blood pressure in the lungs) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in the hands or abdomen.

Silectone 25 Tablet contains spironolactone (a short-acting diuretic), which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Your doctor will advise you how often you should take Silectone 25 Tablet based on your medical condition. In some cases, Silectone 25 Tablet may cause common side effects such as hypotension (low blood pressure), dehydration, drowsiness, dizziness, hyperkalaemia (high potassium levels), hyponatraemia (low sodium levels), elevated creatinine levels, headache, vomiting, nausea, diarrhoea, fatigue, weakness, lethargy (somnolence), gynaecomastia (breast enlargement in males), and amenorrhea (absence of periods in females). Most of these side effects of Silectone 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking Silectone 25 Tablet, inform your doctor if you are allergic to any of its ingredients. Do not stop taking Silectone 25 Tablet of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Let your doctor know if you have any kidney, liver, or heart disease. Do not take Silectone 25 Tablet if you have severe kidney impairment, high potassium levels, or low sodium levels, or if you are taking any potassium supplements, potassium-sparing diuretics (such as eplerenone), or a combination of an angiotensin receptor blocker (ARB) and an angiotensin-converting enzyme (ACE) inhibitor. Silectone 25 Tablet is not recommended during pregnancy unless strongly suggested by your doctor. Please consult your doctor so that the dosage of Silectone 25 Tablet can be prescribed accordingly. Breastfeeding should be avoided during treatment with Silectone 25 Tablet.

Silectone 25 Tablet is primarily used in the treatment of oedema and hypertension. It is effective in managing the following conditions:<br/> • Oedema (Fluid Retention): Silectone 25 Tablet is used to treat oedema associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It helps remove excess fluid in the body by increasing the urine output from the kidneys.<br/> • Hypertension (High Blood Pressure): Silectone 25 Tablet helps lower high blood pressure by blocking aldosterone, thereby reducing water and sodium retention.<br/> • Heart failure: Silectone 25 Tablet is prescribed to improve survival and reduce hospitalisation in patients with severe heart failure, particularly those with NYHA Class III-IV symptoms who are not responding adequately to standard treatments.<br/> • Hypokalaemia (Low Blood Potassium Levels): Silectone 25 Tablet is effective in treating or preventing low potassium levels, especially in patients taking digitalis or when other therapies are ineffective.<br/> • Primary Hyperaldosteronism (Conn's Syndrome): Silectone 25 Tablet is used in both the treatment and diagnosis of this condition, helping to manage associated hypertension and hypokalaemia.<br/> • Ascites (Abdominal Fluid Buildup): In patients with cirrhosis (liver disease), Silectone 25 Tablet is used in combination with water pills/loop diuretics (such as furosemide) to manage ascites by enhancing fluid removal.<br/>

• Silectone 25 Tablet can be taken with or without food. However, taking it with food may help reduce side effects like nausea (feeling sick).
• It is usually taken once daily in the morning; however, your doctor may adjust the dose of this medication based on your medical condition.
• Swallow the medication as a whole with water.
• Do not crush, break, or chew it.

Silectone 25 Tablet contains 'Spironolactone', which acts as a short-acting diuretic (water pill) prescribed for the treatment of hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. Silectone 25 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Do not take Silectone 25 Tablet if you are allergic to any of its ingredients. Avoid taking Silectone 25 Tablet if you have low blood pressure (less than 90 mm of Hg), severe kidney disease (with creatinine clearance less than 30 mL/min), liver disease, hyperkalaemia (high potassium levels), hyponatraemia (low sodium levels), or a history of heart attack. Silectone 25 Tablet is also contraindicated in hypotension (low blood pressure), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (inability to urinate), diabetes (high blood sugar), and aortic stenosis (heart valve problem). Silectone 25 Tablet is not recommended during pregnancy unless clearly advised by your doctor. Please consult your doctor so that the dosage of Silectone 25 Tablet can be prescribed accordingly. Breastfeeding should be avoided during treatment with Silectone 25 Tablet. Do not stop taking Silectone 25 Tablet of your own, as doing so may raise your blood pressure and increase the risk of heart disease and stroke. Avoid taking any extra potassium supplements or consuming potassium-rich foods (such as bananas and broccoli) while using Silectone 25 Tablet, as this may lead to an excessive increase in blood potassium levels (hyperkalaemia). Do not take Silectone 25 Tablet if you are also using potassium-sparing diuretics (such as eplerenone) or a combination of an angiotensin receptor blocker (ARB) and an angiotensin-converting enzyme (ACE) inhibitor.