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compositionComposition:ISOXSUPRINE-40MG
prescription
Prescription Medicine
info
Simsox Sr 40mg Tablet 10's

Simsox Sr 40mg Tablet is used to treat and prevent Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), and other conditions involving poor blood flow in the blood vessels (veins and arteries). Besides this, it is also used to relax uterine muscles to prevent premature labour (when the uterus starts contracting for birth earlier than usual). It contains Isoxsuprine, which relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby increasing the blood flow to the muscles and blocking nerves, delaying contraction in premature labour pains, and poor blood flow to organs and other body parts. In some cases, you may experience side effects such as chest pain (angina), irregular heartbeat, nausea, vomiting, and weakness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISOXSUPRINE-40MG

Manufacturer/Marketer :

Shimmer Pharma

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Simsox Sr 40mg Tablet

Simsox Sr 40mg Tablet is a prescription medication used to treat health conditions caused by poor blood circulation in the blood vessels. It is commonly prescribed to help relieve symptoms of blood vessel spasms and narrowing, such as coldness, numbness, or cramping in the hands, feet, and legs.

To get the best results, you must take this medicine regularly and consistently exactly as prescribed by your doctor. You can take it with or without food, though taking it with meals or a glass of milk can help prevent stomach upset. Incorporating healthy habits, such as regular physical activity and keeping your body warm, can also support your treatment.

While taking Simsox Sr 40mg Tablet , you might experience mild side effects like dizziness, skin flushing, or a fast heartbeat. These symptoms are usually temporary, but you should contact your doctor immediately if you experience severe chest pain, extreme dizziness, or signs of a serious allergic reaction.

Talk to your doctor before starting Simsox Sr 40mg Tablet if you have a bleeding disorder, have recently given birth, have heart disease, glaucoma, or low blood pressure, as this medicine may not be suitable for everyone. 

This medication can interact with other drugs, especially those used to lower blood pressure, which can lead to severe lightheadedness. Additionally, avoid smoking and drinking alcohol, as both can interfere with how the medicine works or make side effects worse. If you are pregnant, breastfeeding, or an older adult, consult your healthcare provider before taking this medicine. Simsox Sr 40mg Tablet should be used under medical supervision, and your doctor may review your response to treatment periodically to ensure it is providing the expected benefits. 

Uses of Simsox Sr 40mg Tablet

Simsox Sr 40mg Tablet may be prescribed for the following conditions related to reduced blood circulation: 

  • Peripheral vascular disease: Simsox Sr 40mg Tablet may help improve blood flow by relaxing blood vessels and is prescribed in some patients with circulation disorders in the arms and legs, easing cramps, numbness, and coldness.
  • Raynaud's phenomenon: It relieves spasms in the small blood vessels of the fingers and toes, preventing them from turning blue, cold, or painful when exposed to cold temperatures.
     

Key Benefits

Simsox Sr 40mg Tablet helps improve blood circulation by relaxing and widening blood vessels. Better blood flow allows oxygen and nutrients to reach tissues more effectively, helping relieve symptoms caused by poor circulation. Its benefits include: 

  • Improves Blood Flow: Helps widen blood vessels and improve circulation to different parts of the body.
  • Relieves Leg Pain While Walking: May reduce cramping, aching, and discomfort in the legs caused by reduced blood flow during physical activity.
  • Reduces Coldness and Numbness: Helps improve circulation to the hands and feet, reducing symptoms such as coldness, numbness, and tingling.
  • Supports Tissue Oxygenation: Enhances the delivery of oxygen and nutrients to tissues that are not receiving adequate blood supply.
  • Improves Daily Comfort and Mobility: Better circulation may help improve physical activity tolerance and overall comfort during daily activities.
     
Side effects of Simsox Sr 40mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

To use Simsox Sr 40mg Tablet safely and effectively, follow these instructions: 

  • Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
  • You can take this medicine with or without food. If it upsets your stomach, try taking it with meals or a glass of milk.
  • Take the medicine at the same times every day to keep a steady level in your body.

Always follow your doctor's exact instructions regarding your treatment plan.
 

How Simsox Sr 40mg Tablet Works

The active ingredient in Simsox Sr 40mg Tablet , isoxsuprine, is a vasodilator (a medicine that widens blood vessels). It works by acting on certain receptors in the body to relax the smooth muscles present in the walls of blood vessels, causing the blood vessels to widen. As the blood vessels widen, blood can flow more freely to different parts of the body, particularly the hands, feet, and legs. This improved circulation increases the delivery of oxygen and nutrients to tissues that are not receiving an adequate blood supply. By improving blood flow, Simsox Sr 40mg Tablet helps reduce symptoms associated with poor circulation, such as coldness, numbness, tingling, and muscle cramps, while supporting overall tissue health and function.
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Alcohol

Safe if prescribed

No interaction found; in case of any discomfort, consult your doctor.

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Pregnancy

Safe if prescribed

Simsox Sr 40mg Tablet is a category C pregnancy; studies suggest it is safe and does not harm the baby. Your doctor will still weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Safe if prescribed

Simsox Sr 40mg Tablet is a category C pregnancy; studies suggest it safe and does not pass through the milk. Your doctor will still weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

Drive with caution, Simsox Sr 40mg Tablet may cause blurry vision, and dizziness may occur.

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Liver

Safe if prescribed

There is limited information available on the use of Simsox Sr 40mg Tablet in patients with liver disease. Please consult your doctor for the best advice.

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Kidney

Safe if prescribed

There is limited information available on the use of Simsox Sr 40mg Tablet in patients with kidney disease. Please consult your doctor for the best advice.

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Children

Unsafe

Simsox Sr 40mg Tablet is not recommended for children as the safety and effectiveness of Simsox Sr 40mg Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Simsox Sr 40mg Tablet or not.

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Heart

Consult your doctor

Please consult your doctor before using Simsox Sr 40mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Simsox Sr 40mg Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giivng Simsox Sr 40mg Tablet to geriatric patients. Your doctor will prescribe Simsox Sr 40mg Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Simsox Sr 40mg Tablet

Do not take more than the prescribed dose of Simsox Sr 40mg Tablet as it may cause overdose. The symptoms of overdose include fainting, lightheadedness, weakness, vomiting and nausea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid Smoking: Stop smoking, as nicotine narrows blood vessels and may reduce the effectiveness of Simsox Sr 40mg Tablet .
  • Avoid Alcohol: Do not consume alcohol while taking Simsox Sr 40mg Tablet , as it may increase dizziness and cause excessive lowering of blood pressure.
  • Keep Extremities Warm: Wear warm socks and gloves when needed to help maintain circulation in your hands and feet.
  • Stay Physically Active: Engage in regular moderate exercise, such as walking, to support healthy blood flow and circulation.
  • Stay Well-Hydrated: Drink adequate water throughout the day unless your doctor advises otherwise.
    Avoid Tight Clothing: Wear comfortable clothing and footwear that do not restrict blood flow to your arms and legs.
     

Have a query?

How Soon It Starts Working

The time required for Simsox Sr 40mg Tablet to start to work: The time required for Simsox Sr 40mg Tablet to show its action is not clinically established. The time for which the effects of Simsox Sr 40mg Tablet last: The duration of action for Simsox Sr 40mg Tablet is not clinically established.

What if you forget to take Simsox Sr 40mg Tablet

If you miss a dose of Simsox Sr 40mg Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

Store the tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from light and moisture.

Drug Warnings

  • Monitor Symptom Improvement: Inform your doctor if symptoms such as coldness, numbness, leg pain, or circulation problems do not improve or worsen during treatment.
  • Stand Up Slowly: Rise gradually from sitting or lying positions to help prevent dizziness and reduce the risk of falls.
  • Use Caution During Activities: Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness or lightheadedness.
  • Monitor Your Heart Rate: Check your pulse regularly and inform your doctor if you notice a fast, pounding, or irregular heartbeat.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Simsox Sr 40mg Tablet :

  • Blood Pressure Medicines and Vasodilators: Taking Simsox Sr 40mg Tablet with other blood pressure-lowering medicines or vasodilators may increase the risk of dizziness and low blood pressure.

Drug-Food Interactions

Certain foods and beverages may increase the likelihood of side effects while taking Simsox Sr 40mg Tablet :

  • Alcohol: Avoid alcohol while taking Simsox Sr 40mg Tablet , as it may increase the risk of dizziness, lightheadedness, and low blood pressure.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Simsox Sr 40mg Tablet , as it may worsen your condition or cause complications.

  • Bleeding Disorders: Do not use this medicine if you have a bleeding disorder, as it may increase the risk of bleeding.
  • Recent Childbirth: This medicine is generally not recommended immediately after childbirth because it may increase the risk of bleeding. Inform your doctor if you have recently delivered a baby before starting treatment.
  • Coronary Artery Disease: Use with caution if you have severe coronary artery disease, as this medicine may worsen certain heart-related symptoms.
  • Glaucoma: Inform your doctor if you have glaucoma, as Simsox Sr 40mg Tablet may require careful monitoring.
  • Low Blood Pressure: Use with caution if you have low blood pressure, as this medicine may further lower your blood pressure.
     
IsoxsuprineTizanidine
Severe

Drug-Drug Interactions

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IsoxsuprineTizanidine
Severe
How does the drug interact with Simsox Sr 40mg Tablet:
Co-administration of Simsox Sr 40mg Tablet and tizanidine may lead to low blood pressure, which may result in side effects.

How to manage the interaction:
Taking Tizanidine with Simsox Sr 40mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, lightheadedness, fainting, changes in pulse or heart rate, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BETA- ADRENERGIC BLOCKERS]

FAQs

Simsox Sr 40mg Tablet is used to treat and prevent Raynaud's phenomenon, cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries), and other conditions involving poor blood flow in the blood vessels (veins and arteries). Besides this, it is also used to relax uterine muscles to prevent premature labour (when the uterus starts contracting for birth earlier than usual).
Simsox Sr 40mg Tablet contains Isoxsuprine, which relaxes and widens the blood vessels (artery/veins) and muscles (like uterine muscle), thereby increasing the blood flow to the muscles and blocking nerves, delaying contraction in premature labour pains, and poor blood flow to organs and other body parts.
If you forget to take Simsox Sr 40mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
There are no known reported contraindications to oral use of Simsox Sr 40mg Tablet when administered in recommended doses. Simsox Sr 40mg Tablet should not be given immediately postpartum (childbirth) or in the presence of arterial (blood vessel) bleeding.
If you are taking Simsox Sr 40mg Tablet and undergoing dental surgery, please inform your doctor as Simsox Sr 40mg Tablet might be stopped before the surgery.
No, Simsox Sr 40mg Tablet is in a class of drugs called vasodilators.
You may take Simsox Sr 40mg Tablet with or without food.
The dose is dependent on individual factors. Take Simsox Sr 40mg Tablet exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.
In some cases, Simsox Sr 40mg Tablet may cause side effects including weakness, dizziness, flushing (feeling of warmth), upset stomach, vomiting and stomach pain. Most of these side effects of Simsox Sr 40mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
It is best to avoid or limit alcohol while taking Simsox Sr 40mg Tablet . Alcohol can worsen side effects like dizziness, lightheadedness, and low blood pressure. Talk to your doctor or pharmacist if you have questions about alcohol use.
The time it takes to see results can vary. Depending on the condition being treated and your individual response to therapy, some people notice an improvement in their symptoms within a few days, while for others, it may take several weeks. Talk to your doctor if your symptoms do not improve.
The safety of Simsox Sr 40mg Tablet during pregnancy has not been fully established. It should only be used if your doctor determines that the potential benefits outweigh the possible risks. If you are pregnant, planning to become pregnant, or think you may be pregnant, talk to your doctor before taking this medicine.
Yes. If you have recently delivered a baby, inform your doctor before starting Simsox Sr 40mg Tablet . This medicine is generally not recommended immediately after childbirth, particularly if there is ongoing bleeding or a higher risk of bleeding complications. Your doctor will assess whether this medicine is suitable for you and may recommend an alternative treatment if needed.
Yes, dizziness is a common side effect of Simsox Sr 40mg Tablet , especially when you stand up quickly. To prevent this, rise slowly from a sitting or lying position. Talk to your doctor if the dizziness is severe or does not go away.
Yes, smoking can significantly reduce the effectiveness of Simsox Sr 40mg Tablet . Nicotine causes blood vessels to narrow, which directly counteracts the widening effect of this medicine. Talk to your doctor for support with quitting smoking.
You can take Simsox Sr 40mg Tablet with or without food. However, if the medicine upsets your stomach, taking it with a meal or a glass of milk can help prevent nausea. Talk to your doctor or pharmacist for personalised advice.
A fast or pounding heartbeat can occur while taking Simsox Sr 40mg Tablet . Contact your doctor promptly if you develop a new, severe, persistent, or worsening fast heartbeat, especially if it occurs with chest pain, dizziness, shortness of breath, or fainting. Seek immediate medical attention if these symptoms are severe.
You should not stop taking Simsox Sr 40mg Tablet without consulting your healthcare provider first. Stopping the medicine abruptly can cause your blood circulation symptoms to return. Talk to your doctor about how to safely manage your treatment.
The duration of treatment depends on the condition being treated and your response to therapy. Some people may require treatment for a few weeks, while others may need longer-term therapy. Your doctor will review your progress regularly and decide how long treatment should continue.
The safety and effectiveness of Simsox Sr 40mg Tablet in children have not been clearly established. This medicine should only be used in children if specifically prescribed and monitored by a doctor.
If your symptoms do not improve after a few weeks of treatment, or if they worsen despite taking Simsox Sr 40mg Tablet as prescribed, contact your doctor. They may reassess your condition, review other possible causes of your symptoms, adjust your treatment plan, or consider alternative therapies if appropriate.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

d-40, saket colony, near adrsh nagar thana, adarsh nagar, jaipur, rajasthan, 302003, india
Other Info - SIM0062

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