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  3. Stadin Plus 150mg/30mg Tablet

Stadin Plus 150mg/30mg Tablet, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Stadin Plus 150mg/30mg Tablet is an antiretroviral drug used to treat HIV infection. It helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). It contains Lamivudine and Stavudine, which work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, they help treat HIV infections. The common side effects of this medicine are nausea, anorexia (an eating disorder), vomiting, dyspepsia (indigestion), abdominal pain, rash, fever, malaise (general discomfort), asthenia (weakness), headache, and insomnia.

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Composition :

LAMIVUDINE-150MG + STAVUDINE-30MG

Manufacturer/Marketer :

Sain Medicaments Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Stadin Plus 150mg/30mg Tablet

Stadin Plus 150mg/30mg Tablet belongs to a class of antiretroviral drugs used to treat HIV infection. Stadin Plus 150mg/30mg Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses.

Stadin Plus 150mg/30mg Tablet contains Lamivudine and Stavudine. Both Lamivudine and Stavudine are nucleoside reverse transcriptase inhibitors. Stadin Plus 150mg/30mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Stadin Plus 150mg/30mg Tablet helps treat HIV infections.

Stadin Plus 150mg/30mg Tablet is a prescription medication. You should take this medicine exactly as prescribed by the doctor. The common side effects of Stadin Plus 150mg/30mg Tablet are nausea, anorexia (an eating disorder), vomiting, dyspepsia (indigestion), abdominal pain, rash, fever, malaise (general discomfort), asthenia (weakness), headache, and insomnia. Most of these side effects of Stadin Plus 150mg/30mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Stadin Plus 150mg/30mg Tablet is not recommended to take Stadin Plus 150mg/30mg Tablet if you are allergic to any of its contents. Stadin Plus 150mg/30mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption. You should not become pregnant while you are taking Stadin Plus 150mg/30mg Tablet. Talk to your doctor about effective birth control methods that you can use during your treatment. If you become pregnant while taking Stadin Plus 150mg/30mg Tablet, call your doctor immediately. You should not breastfeed if you are infected with HIV or if you are taking Stadin Plus 150mg/30mg Tablet. Stadin Plus 150mg/30mg Tablet is not recommended for use in children.

Uses of Stadin Plus 150mg/30mg Tablet

Treatment of HIV infection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Stadin Plus 150mg/30mg Tablet is a combination of two drugs, Lamivudine and Stavudine, used to treat HIV infection. Both Lamivudine and Stavudine are nucleoside reverse transcriptase inhibitors. Stadin Plus 150mg/30mg Tablet interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Thus, Stadin Plus 150mg/30mg Tablet helps treat HIV infections. Taking Stadin Plus 150mg/30mg Tablet along with practising safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

How Stadin Plus 150mg/30mg Tablet Works

Stadin Plus 150mg/30mg Tablet contains Lamivudine and Stavudine. Both Lamivudine and Stavudine are nucleoside reverse transcriptase inhibitors. Stadin Plus 150mg/30mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for virus reproduction. Together, Stadin Plus 150mg/30mg Tablet helps treat HIV infections.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Stadin Plus 150mg/30mg Tablet

Do not take more than the prescribed dose. If you take more than prescribed dose accidentally, it may lead to unwanted effects. Please go to the emergency department of the closest hospital or call doctor right away. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Talk to your doctor about the risks and benefits of taking Stadin Plus 150mg/30mg Tablet. Before taking the Stadin Plus 150mg/30mg Tablet, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Stadin Plus 150mg/30mg Tablet is not recommended for children. You are advised to take proper precautions if you are infected with HIV to prevent infection from spreading to others through sexual contact or body fluids. Stavudine in Stadin Plus 150mg/30mg Tablet can cause significant or fatal lactic acidosis (a buildup of acid in the blood), which will most likely require hospitalization. Lactic acidosis is more likely to develop if you are a woman, overweight, or have been treated with human immunodeficiency virus (HIV) drugs for an extended time. If you are pregnant and taking stavudine in addition to didanosine, your risk may increase. Inform your doctor if you have or have previously had a liver illness, which includes hepatitis C virus infection.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
LamivudineZalcitabine
Severe

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Stadin Plus 150mg/30mg Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
LamivudineZalcitabine
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Stadin Plus 150mg/30mg Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineMipomersen
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Taking Stadin Plus 150mg/30mg Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Stadin Plus 150mg/30mg Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
LamivudineTeriflunomide
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Teriflunomide can cause Stadin Plus 150mg/30mg Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Stadin Plus 150mg/30mg Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Combining Stadin Plus 150mg/30mg Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Stadin Plus 150mg/30mg Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineLomitapide
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Taking Stadin Plus 150mg/30mg Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Stadin Plus 150mg/30mg Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
LamivudineBexarotene
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Taking bexarotene together with Stadin Plus 150mg/30mg Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Stadin Plus 150mg/30mg Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Stadin Plus 150mg/30mg Tablet:
Stadin Plus 150mg/30mg Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Stadin Plus 150mg/30mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis, as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich foods such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Stadin Plus 150mg/30mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consumption of alcohol should be avoided.

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Pregnancy

Unsafe

Stadin Plus 150mg/30mg Tablet is not suggested during pregnancy. You should not become pregnant while you are taking Stadin Plus 150mg/30mg Tablet. Ask your doctor about effective birth control options that you can use during your therapy. If you become pregnant while taking Stadin Plus 150mg/30mg Tablet, call your doctor right away.

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Breast Feeding

Unsafe

You should not breastfeed if you are infected with HIV or if you are taking Stadin Plus 150mg/30mg Tablet.

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Driving

Caution

Stadin Plus 150mg/30mg Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Stadin Plus 150mg/30mg Tablet.

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Liver

Caution

Take Stadin Plus 150mg/30mg Tablet with caution, especially if you have a history of liver diseases. Inform your doctor if you have liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Take Stadin Plus 150mg/30mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Stadin Plus 150mg/30mg Tablet is not recommended for children.

Have a query?

FAQs

Stadin Plus 150mg/30mg Tablet is used to treat HIV infection.

Stadin Plus 150mg/30mg Tablet contains Lamivudine and Stavudine. Stadin Plus 150mg/30mg Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes, which are necessary to reproduce the virus. Together, Stadin Plus 150mg/30mg Tablet helps treat HIV infections.

Stadin Plus 150mg/30mg Tablet does not cure HIV infection. Stadin Plus 150mg/30mg Tablet reduces the amount of HIV in the body and improves the immune system's functioning.

HIV infection may still be transmitted to other persons while using Stadin Plus 150mg/30mg Tablet. Stadin Plus 150mg/30mg Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to avoid transmission of HIV while taking Stadin Plus 150mg/30mg Tablet.

Do not stop taking Stadin Plus 150mg/30mg Tablet without consulting your doctor and without completing the prescribed course, as abrupt stopping may worsen your condition or it can lead to other infections. If you find difficulty using Stadin Plus 150mg/30mg Tablet, seek immediate medical help.

Stadin Plus 150mg/30mg Tablet is a combination medication that belongs to the group of medications called antiretroviral drugs used to treat HIV infection. It helps to reduce the risk of developing AIDS (acquired immunodeficiency syndrome). Both lamivudine and stavudine are nucleoside reverse transcriptase inhibitors (NRTIs). They work by inhibiting the activity of reverse transcriptase enzymes, which are essential for the replication of HIV. Together, they help treat HIV infections.

Yes, Stadin Plus 150mg/30mg Tablet is safe if taken in the dose and duration exactly as prescribed by the doctor.

Stadin Plus 150mg/30mg Tablet should be taken orally. Swallow it as a whole with a glass of water. Do not chew, crush or break it.

Yes, Stadin Plus 150mg/30mg Tablet is effective in treating HIV infection as it contains nucleoside reverse transcriptase inhibitors (NRTIs) that work by blocking the reverse transcriptase enzyme, which is necessary for the virus to replicate. This helps to prevent the progression of AIDS, and improves immune function. However, the effectiveness of Stadin Plus 150mg/30mg Tablet may vary depending on the individual and their specific condition.

If you forget to take a dose of Stadin Plus 150mg/30mg Tablet, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and take your next dose at the regular time. Do not double the dose.

The side effects of Stadin Plus 150mg/30mg Tablet include anorexia (an eating disorder), nausea, vomiting, dyspepsia (indigestion), abdominal pain, rash, fever, malaise (general discomfort), asthenia (weakness), headache, and insomnia. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Arbro Pharmaceuticals Pvt.Ltd. , 6 / 14 , Kirti Nagar, Industrial Area, New Delhi-110015, India
Other Info - ST97225

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:31 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.7066.pdf
  2. https://www.drugs.com/cdi/lamivudine-tablets.html
  3. https://go.drugbank.com/drugs/DB00649
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020412s029,020413s020lbl.pdf
  5. https://reference.medscape.com/drug/zerit-d4t-stavudine-342630
  6. https://medlineplus.gov/druginfo/meds/a694033.html
  7. https://pubchem.ncbi.nlm.nih.gov/compound/Stavudine
  8. https://www.drugs.com/drug-interactions/stavudine-index.html
  9. https://www.drugs.com/drug-interactions/lamivudine.html
  10. https://clinicalinfo.hiv.gov/en/guidelines/perinatal/archived-drugs-stavudine-zerit#:~:text=Stavudine%20is%20classified%20as%20Food,HIV%20due%20to%20its%20toxicity.
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