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compositionComposition:USTEKINUMAB-5MG
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Prescription Medicine
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₹48586 with coupons & bank offers*

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Stelara 130 mg/26 ml Injection is used to treat Ulcerative colitis (18 years and older), Crohn's disease (18 years and older), Severe psoriasis (6 years and older), and Psoriatic arthritis (6 years and older). It contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins in the body that contribute to inflammation and immune responses. Common side effects of Stelara 130 mg/26 ml Injection include nasal congestion, runny nose, sore throat, fever, headache, tiredness, itching, nausea and vomiting, diarrhoea, stomach pain, joint pain and redness at the injection site.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

USTEKINUMAB-5MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Stelara 130 mg/26 ml Injection

Stelara 130 mg/26 ml Injection is a prescription injection used to treat chronic inflammatory conditions, including moderate to severe plaque psoriasis, active psoriatic arthritis, Crohn's disease, and ulcerative colitis. By targeting specific pathways in the immune system, it helps calm overactive inflammation that affects your skin, joints, or digestive tract.

To get the best results, it is important to take this medicine consistently as prescribed by your healthcare provider. Because it is given as an injection, food intake does not affect how it works. Making certain lifestyle adjustments, such as managing your daily stress levels and eating a nutrient-dense diet, can also support your treatment journey.

While this medicine is generally well-tolerated, some people may experience mild side effects like cold-like symptoms, headaches, or redness at the injection site. However, serious side effects such as severe infections or severe allergic reactions can occur. You must consult your doctor immediately if you experience a high fever, severe cough, or difficulty breathing.

Talk to your doctor before starting Stelara 130 mg/26 ml Injection if you have any active infections, a history of tuberculosis, or a weakened immune system. Do not take this if you are currently suffering from a serious, active infection or if you have had a severe allergic reaction to this medicine in the past.

This medicine may interact with other treatments, especially those that suppress the immune system, and live vaccines must be avoided. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist to weigh the benefits and risks before starting treatment.

Uses of Stelara 130 mg/26 ml Injection

Your doctor may prescribe Stelara 130 mg/26 ml Injection to help manage the following conditions:

  • Plaque psoriasis: Used to treat moderate to severe plaque psoriasis in people who need systemic treatment or phototherapy. It helps control the inflammation responsible for the characteristic skin plaques.
  • Psoriatic arthritis: Used to treat active psoriatic arthritis, either alone or with methotrexate. It helps control inflammation affecting the joints and may also improve associated psoriasis.
  • Crohn's disease: Used to treat moderate to severe active Crohn's disease. It reduces inflammation in the digestive tract and can help induce and maintain remission.
  • Ulcerative colitis: Used to treat moderate to severe active ulcerative colitis. It reduces inflammation in the colon and can help induce and maintain remission.

Key Benefits

When used as directed as part of your treatment plan, Stelara 130 mg/26 ml Injection may provide the following benefits:

  • Improves skin symptoms: In plaque psoriasis, Stelara 130 mg/26 ml Injection can reduce the redness, scaling, thickness, and itching of plaques, improving skin comfort and making symptoms easier to manage.
  • Improves joint symptoms and movement: In psoriatic arthritis, reducing inflammation can ease joint pain, swelling, and stiffness, helping you move more comfortably and carry out daily activities.
  • Helps control bowel symptoms: In Crohn's disease and ulcerative colitis, reducing inflammation can improve symptoms such as diarrhoea, abdominal pain, rectal bleeding, and bowel urgency, depending on the condition.
  • Supports longer-term symptom control: In people who respond to treatment, maintenance therapy can help sustain improvement and maintain remission in Crohn's disease or ulcerative colitis.
Side effects of Stelara 130 mg/26 ml Injection
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor’s recommendations for the correct dosage and timing of this medication.
  • Stelara 130 mg/26 ml Injection comes in a prefilled syringe to be given by a healthcare professional; if you are well-trained and advised by your doctor to administer Stelara 130 mg/26 ml Injection at home, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
  • Choose an injection site such as the thigh, upper arm, or abdomen; pinch the skin and inject the advised dose slowly and steadily, then remove the needle.
  • Rotate the injection site each time. Do not inject into skin that is red, bruised, or hard.
  • Wash your hands before and after administration.
  • Do not use Stelara 130 mg/26 ml Injection if it is frozen or if the liquid is cloudy or contains small particles.

How Stelara 130 mg/26 ml Injection Works

Stelara 130 mg/26 ml Injection contains ustekinumab. Ustekinumab is a monoclonal antibody that binds to the p40 protein subunit shared by two immune signalling proteins, interleukin-12 (IL-12) and interleukin-23 (IL-23). By preventing these proteins from interacting with their receptor on certain immune cells, ustekinumab reduces inflammatory immune signalling. This helps control the inflammation involved in plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis, thereby improving symptoms and helping control disease activity.
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Alcohol

Caution

Avoid consuming alcohol while on treatment with this medicine.

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Pregnancy

Caution

The safety of Stelara 130 mg/26 ml Injection in pregnant women is unknown. Therefore, please consult your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine. Women of childbearing potential should take effective contraception throughout and for at least 15 weeks after therapy.

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Breast Feeding

Caution

It is unknown whether Stelara 130 mg/26 ml Injection is excreted in human milk. It should not be used while breastfeeding unless the possible benefits outweigh the risks to the infant. Do not breastfeed unless your doctor recommends it if you are a nursing mother.

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Driving

Caution

Drive only if you are alert, as the Stelara 130 mg/26 ml Injection may cause tiredness in some people.

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Liver

Caution

Limited information was available about using Stelara 130 mg/26 ml Injection in patients with liver disease. Inform your doctor before receiving the Stelara 130 mg/26 ml Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available about using Stelara 130 mg/26 ml Injection in patients with kidney disease. Inform your doctor before receiving the Stelara 130 mg/26 ml Injection if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Stelara 130 mg/26 ml Injection can be used to treat severe psoriasis and psoriatic arthritis in children above six years of age.

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Heart

Consult your doctor

Please consult your doctor before receiving Stelara 130 mg/26 ml Injection if you have pre-existing heart problems. Your doctor will prescribe Stelara 130 mg/26 ml Injection if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Stelara 130 mg/26 ml Injection to geriatric patients. Your doctor will prescribe Stelara 130 mg/26 ml Injection if the benefits outweigh the risks.

What if I have taken an overdose of Stelara 130 mg/26 ml Injection

If you suspect you have injected too much of this medicine, seek immediate medical attention, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Track your food: If you are treating Crohn's or ulcerative colitis, keep a daily food journal to identify and avoid personal trigger foods that can worsen inflammation.
  • Eat anti-inflammatory foods: Focus on a balanced diet rich in leafy greens, berries, and healthy fats like olive oil and wild-caught fish, which naturally help manage systemic inflammation.
  • Choose low-impact exercises: For joint pain from psoriatic arthritis, engage in gentle activities like swimming, stationary cycling, or yoga to keep your joints flexible without causing strain.
  • Moisturise your skin regularly: If you have psoriasis, apply thick, fragrance-free moisturisers immediately after bathing to lock in moisture and protect your skin barrier.
  • Avoid smoking: Smoking can significantly reduce the effectiveness of your treatment and is a known trigger for both psoriasis flares and severe bowel inflammation.
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Have a query?

How Soon It Starts Working

The time required for Stelara 130 mg/26 ml Injection to start to work: The time required for Stelara 130 mg/26 ml Injection to show its action is not clinically established. The time for which the effects of Stelara 130 mg/26 ml Injection last: The duration of action for Stelara 130 mg/26 ml Injection is not clinically established.

What if you forget to take Stelara 130 mg/26 ml Injection

If you miss a scheduled injection, contact your doctor or pharmacist as soon as possible to get a new schedule. Do not inject a double dose to make up for the missed one.

Storage

• Store Stelara 130 mg/26 ml Injection in the refrigerator between 2°C and 8°C.

Drug Warnings

  • Inspect before injecting: Check the appearance of the solution every single time; it must be clear or slightly pearly, and never cloudy or discoloured.
  • Rotate your injection sites: Inject in a different spot each time (thigh, abdomen, or outer upper arm) to prevent skin irritation or thickening.
  • Avoid damaged skin: Never inject into skin areas that are bruised, tender, red, hard, or actively affected by psoriasis plaques.
  • Watch out for live vaccines: Do not receive any live vaccines while using this medicine, as your body's immune defence is lowered.
  • Complete a tuberculosis check: Ensure your doctor tests you for tuberculosis (TB) before you begin treatment, as latent TB can reactivate during therapy.

Drug-Drug Interactions

verifiedApollotooltip
  • Immunosuppressive medicines: Taking Stelara 130 mg/26 ml Injection with other drugs that lower your immune system can significantly increase your risk of developing a serious infection.
  • Live vaccines: Combining this medicine with live viral or bacterial vaccines may cause the vaccine to trigger an actual infection instead of providing immunity.
  • Certain liver-processed medicines: This medicine can temporarily affect how your liver processes other medications (such as cyclosporine or warfarin), which may require your doctor to adjust your other doses.
UstekinumabBaricitinib
Severe

Drug-Drug Interactions

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UstekinumabBaricitinib
Severe
How does the drug interact with Stelara 130 mg/26 ml Injection:
Taking Baricitinib with Stelara 130 mg/26 ml Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Baricitinib and Stelara 130 mg/26 ml Injection, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Stelara 130 mg/26 ml Injection when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MONOCLONAL ANTIBODIES]

FAQs

Stelara 130 mg/26 ml Injection is used to treat Ulcerative colitis (18 years and older) Crohn’s disease (18 years and older) Severe psoriasis (6 years and older) and Psoriatic arthritis (6 years and older).
Stelara 130 mg/26 ml Injection contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins (interleukin-12 and interleukin-23) in the body that contribute to inflammation and immune responses.
If you have an infection (Bacterial/Fungal/Protozoal/Viral), must inform your doctor. Your doctor will weigh the benefits over the risks before prescribing Stelara 130 mg/26 ml Injection.
You are recommended not to take Stelara 130 mg/26 ml Injection with other medications without doctor's notice, especially immunosuppressant medications.
Before receiving Stelara 130 mg/26 ml Injection, inform your doctor if you are suffering from lung infections because some persons who receive Stelara 130 mg/26 ml Injection have developed lung inflammation, which can be fatal. These lung issues may necessitate hospitalization. Inform your doctor immediately if you develop lung infections, shortness of breath, or a cough that does not go away while taking Stelara 130 mg/26 ml Injection.
Yes, once your doctor or nurse has trained you on the correct technique, you can safely inject it at home. However, your first dose for certain bowel conditions is typically administered via an IV infusion in a clinic. Talk to your doctor or pharmacist if you feel nervous about the injection process.
Because this medicine lowers your body's ability to fight off germs, you should contact your doctor immediately if you develop any signs of infection, such as a fever, chills, or a persistent cough. Do not take your next scheduled dose until you have spoken with your healthcare provider. Talk to your doctor for guidance.
Yes, you can receive non-live vaccines like the annual flu shot, though they may be slightly less effective because of your modified immune response. However, you must avoid live vaccines during treatment. Talk to your doctor before receiving any vaccine.
The safety of this medicine in pregnant women is not fully established, though it is known to cross the placenta in later stages of pregnancy. It should only be used if the potential benefit justifies the potential risk to the foetus. Talk to your doctor if you are pregnant or planning to become pregnant.
There is no known direct interaction between alcohol and this medicine. However, alcohol can act as a trigger, worsening skin inflammation in psoriasis or gut inflammation in bowel diseases. Talk to your doctor or pharmacist about how alcohol might affect your specific condition.
Hair loss is not a recognised side effect of this medicine. If you notice unexpected hair thinning, it may be due to other medications, stress, or your underlying inflammatory condition. Talk to your doctor or pharmacist to help determine the cause.
After your initial starting doses, maintenance injections are typically given once every 8 to 12 weeks. Your exact schedule will be customised by your doctor based on your health needs. Talk to your doctor to confirm your specific dosing schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - STE0690

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