Stelara 130 mg/26 ml Injection 1's

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Stelara 130 mg/26 ml Injection is used to treat Ulcerative colitis (18 years and older), Crohn's disease (18 years and older), Severe psoriasis (6 years and older), and Psoriatic arthritis (6 years and older). It contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins in the body that contribute to inflammation and immune responses. Common side effects of Stelara 130 mg/26 ml Injection include nasal congestion, runny nose, sore throat, fever, headache, tiredness, itching, nausea and vomiting, diarrhoea, stomach pain, joint pain and redness at the injection site.

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About Stelara 130 mg/26 ml Injection

Stelara 130 mg/26 ml Injection belongs to a class of monoclonal antibody drugs. It treats various inflammatory conditions, including Crohn's disease and active ulcerative colitis, in adults 18 years and older. It can treat moderate to severe psoriasis and psoriatic arthritis in adults and children six years and older. Crohn's disease is a chronic inflammatory disorder that affects the digestive tract. It is a kind of inflammatory bowel disease (IBD). Psoriasis is a skin disease that causes an itchy, scaly rash on the knees, elbows, trunk, and scalp. Crohn's disease is a chronic inflammatory disorder that affects the digestive tract. It's a form of inflammatory bowel illness.

Stelara 130 mg/26 ml Injection contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins (interleukin-12 and interleukin-23) in the body that contribute to inflammation and immune responses.

Stelara 130 mg/26 ml Injection will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience nasal congestion, runny nose, sore throat, fever, headache, tiredness, itching, nausea and vomiting, diarrhoea, stomach pain, joint pain and redness at the injection site. Most of these side effects of Stelara 130 mg/26 ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Stelara 130 mg/26 ml Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant or breastfeeding. Stelara 130 mg/26 ml Injection may have an impact on your immune system. Stelara 130 mg/26 ml Injection can raise your risk of significant adverse effects. Stelara 130 mg/26 ml Injection may impair your ability to fight infections and put you at risk. Some patients get significant infections while taking Stelara 130 mg/26 ml Injection, such as tuberculosis (TB) and infections caused by bacteria, fungi, or viruses, which may necessitate hospitalization. It is strongly advised that you be tested for tuberculosis before beginning Stelara 130 mg/26 ml Injection treatment and that you be regularly monitored for signs and symptoms of tuberculosis while on Stelara 130 mg/26 ml Injection. If your doctor believes you are at risk for tuberculosis, you may be treated for it before and throughout your Stelara 130 mg/26 ml Injection treatment.

Uses of Stelara 130 mg/26 ml Injection

Stelara 130 mg/26 ml Injection is used in the treatment of Ulcerative colitis, Crohn's disease, Severe psoriasis and Psoriatic arthritis. The detailed uses of Stelara 130 mg/26 ml Injection are as follows: • Plaque Psoriasis: Stelara 130 mg/26 ml Injection is used to treat plaque psoriasis in moderate to severe cases. • Psoriatic Arthritis: Stelara 130 mg/26 ml Injection is used to reduce joint pain and swelling in psoriatic arthritis. • Crohn’s Disease: Stelara 130 mg/26 ml Injection is used to treat crohn’s disease with moderately to severely active disease. • Ulcerative Colitis: Stelara 130 mg/26 ml Injection is used with moderate to severe UC who haven't responded to other treatments.

Directions for Use

• Follow your doctor's recommendations for the correct dosage and timing of this medication.• Stelara 130 mg/26 ml Injection comes in a prefilled syringe to be given by a healthcare professional; if you are well trained and advised by your doctor to administer Stelara 130 mg/26 ml Injection at home, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Choose an injection site such as the thigh, upper arm, or abdomen; pinch the skin and inject the advised dose slowly and steadily, then remove the needle.• Rotate the injection site each time. Do not inject into skin that is red, bruised, or hard. Wash your hands before & after administration. Do not use Stelara 130 mg/26 ml Injection if it is frozen or if the liquid is cloudy or contains small particles.

Medicinal Benefits

Stelara 130 mg/26 ml Injection contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins (interleukin-12 and interleukin-23) in the body that contribute to inflammation and immune responses. Thus, it helps to treat Crohn’s disease and active ulcerative colitis in adults 18 years and older. It can treat moderate to severe psoriasis and psoriatic arthritis in adults and children six years and older.

How Stelara 130 mg/26 ml Injection Works

Stelara 130 mg/26 ml Injection contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins (interleukin-12 and interleukin-23) in the body that contribute to inflammation and immune responses.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Cold chain - To be stored in cold places at 2ÂºC to 8ÂºC.

Side effects of Stelara 130 mg/26 ml Injection

Common Cold

Here are the steps to manage the medication-triggered Common Cold:

Inform your doctor about the common cold symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Common Cold

Here are the steps to manage the medication-triggered Upper respiratory tract infection:

Inform your doctor about the symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Back Pain

Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:

Talk to your doctor about your back pain and potential medication substitutes or dose changes.
Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
To lessen the tension on your back, sit and stand upright and maintain proper posture.
To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
Back discomfort can worsen by bending, twisting, and heavy lifting.
Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Stelara 130 mg/26 ml Injection

Since Stelara 130 mg/26 ml Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Stelara 130 mg/26 ml Injection may suppress your immune system and raise your chance of some cancers and infections, so notify your doctor if you have any infections (bacterial/fungal/protozoal/viral), malignancies or cancers. Also, tell your doctor if you have tuberculosis or PRES (Posterior Reversible Encephalopathy Syndrome) or have ever had an adverse response to Ustekinumab or any of the components in this medicine. Stelara 130 mg/26 ml Injection may cause significant allergic responses in some cases. If you experience any of the following symptoms of a major allergic reaction: feeling faint, swelling of your face, eyelids, tongue, or throat, chest tightness, or skin rash, get medical attention immediately.

Drug-Drug Interactions

UstekinumabBaricitinib

Severe

Drug-Drug Interactions

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UstekinumabBaricitinib

Severe

How does the drug interact with Stelara 130 mg/26 ml Injection:
Taking Baricitinib with Stelara 130 mg/26 ml Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Baricitinib and Stelara 130 mg/26 ml Injection, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help heal faster.
Opt for food and drinks high in omega-3 fatty acids to relieve pain, swelling, and inflammation. Omega 3-rich acid-enriched foods include flaxseeds, walnuts, soybean oil, salmon, and tuna if you prefer non-veg.
Eat more fibre-rich foods such as fruits and vegetables.
Eat smaller meals all day.
Drink small amounts of water throughout the day.
If you are intolerant to lactose, lower your intake of milk.
Avoid foods high in sugar, fat, and processed foods, as these may cause inflammation.
Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

MONOCLONAL ANTIBODIES

Alcohol

Caution

Avoid consuming alcohol while on treatment with this medicine.

Pregnancy

Caution

The safety of Stelara 130 mg/26 ml Injection in pregnant women is unknown. Therefore, please consult your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine. Women of childbearing potential should take effective contraception throughout and for at least 15 weeks after therapy.

Breast Feeding

Caution

It is unknown whether Stelara 130 mg/26 ml Injection is excreted in human milk. It should not be used while breastfeeding unless the possible benefits outweigh the risks to the infant. Do not breastfeed unless your doctor recommends it if you are a nursing mother.

Driving

Caution

Drive only if you are alert, as the Stelara 130 mg/26 ml Injection may cause tiredness in some people.

Liver

Caution

Limited information was available about using Stelara 130 mg/26 ml Injection in patients with liver disease. Inform your doctor before receiving the Stelara 130 mg/26 ml Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

Kidney

Caution

Limited information was available about using Stelara 130 mg/26 ml Injection in patients with kidney disease. Inform your doctor before receiving the Stelara 130 mg/26 ml Injection if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

Children

Safe if prescribed

Stelara 130 mg/26 ml Injection can be used to treat severe psoriasis and psoriatic arthritis in children above six years of age.

Have a query?

FAQs

What is the use of Stelara 130 mg/26 ml Injection?

Stelara 130 mg/26 ml Injection is used to treat Ulcerative colitis (18 years and older) Crohn’s disease (18 years and older) Severe psoriasis (6 years and older) and Psoriatic arthritis (6 years and older).

How does Stelara 130 mg/26 ml Injection work?

Stelara 130 mg/26 ml Injection contains Ustekinumab, a monoclonal antibody that targets and neutralises specific proteins (interleukin-12 and interleukin-23) in the body that contribute to inflammation and immune responses.

Is it safe to use Stelara 130 mg/26 ml Injection on infected individuals?

If you have an infection (Bacterial/Fungal/Protozoal/Viral), must inform your doctor. Your doctor will weigh the benefits over the risks before prescribing Stelara 130 mg/26 ml Injection.

Can I take immunosuppressant medicines with Stelara 130 mg/26 ml Injection?

You are recommended not to take Stelara 130 mg/26 ml Injection with other medications without doctor's notice, especially immunosuppressant medications.

Does Stelara 130 mg/26 ml Injection induce lung infections?

Before receiving Stelara 130 mg/26 ml Injection, inform your doctor if you are suffering from lung infections because some persons who receive Stelara 130 mg/26 ml Injection have developed lung inflammation, which can be fatal. These lung issues may necessitate hospitalization. Inform your doctor immediately if you develop lung infections, shortness of breath, or a cough that does not go away while taking Stelara 130 mg/26 ml Injection.

Country of origin

India

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060

Other Info - STE0690

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

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Stelara 130 mg/26 ml Injection 1's

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What is the use of Stelara 130 mg/26 ml Injection?

How does Stelara 130 mg/26 ml Injection work?

Is it safe to use Stelara 130 mg/26 ml Injection on infected individuals?

Can I take immunosuppressant medicines with Stelara 130 mg/26 ml Injection?

Does Stelara 130 mg/26 ml Injection induce lung infections?

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