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Sufrate LA Cream is used in the treatment of anal fissures, fistula and piles. It promotes the healing of fissures, helps form new, healthy skin, and minimises infection and pain around the anal canal. It may cause side effects such as a skin rash, mild irritation, tingling, or a burning sensation. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LIDOCAINE-4%W/W+METRONIDAZOLE-1%W/W+SUCRALFATE-7%W/W

Manufacturer/Marketer :

Eskag Pharma Pvt Ltd

Consume Type :

Rectal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sufrate LA Cream

Sufrate LA Cream is a specialised rectal medication prescribed to relieve discomfort, pain, and swelling associated with painful anal conditions, such as anal fissures (small tear in the anus lining) and haemorrhoids (piles). By targeting local inflammation, easing pain, and protecting raw skin, it helps speed up the natural recovery process in the delicate anorectal region. It is designed to make daily activities and bowel movements significantly more comfortable.

For optimal results, Sufrate LA Cream is typically applied rectally once or twice daily, or exactly as directed by your healthcare provider. Consistency is key to managing pain and ensuring proper healing of the affected tissues. Alongside using this medication, incorporating a high-fiber diet, drinking plenty of water, and avoiding straining during bowel movements will significantly support your recovery.

While using Sufrate LA Cream, you may experience mild and temporary local side effects, such as a slight burning or itching sensation at the site of application. However, if you experience severe irritation, a worsening of pain, or signs of an allergic reaction, you must stop using the medication and consult your doctor immediately.

Before starting Sufrate LA Cream, inform your doctor if you have any pre-existing health conditions, particularly liver damage or a history of blood disorders such as low white blood cell counts (leukopenia) or other blood cell abnormalities. Do not use this medication if you have a known allergy to any of its active components, as severe allergic reactions can occur in rare cases.

Some medications, alcohol, and smoking may interact with this treatment; for instance, alcohol should be avoided during treatment to prevent potential unpleasant interactions with the antibacterial component. If you are pregnant, breastfeeding, or an elderly patient, talk to your doctor or pharmacist to ensure this medication is safe for you to use.

Uses of Sufrate LA Cream

Sufrate LA Cream is used in the treatment of Anorectal diseases (piles, fistula, fissure). The detailed uses of Sufrate LA Cream are as follows:

  • Anal fissures: Sufrate LA Cream helps by numbing intense pain, reducing localised swelling, and forming a protective barrier over the small tears in the lining of the anus, allowing them to heal safely.
  • Haemorrhoids (piles): Sufrate LA Cream relieves the throbbing pain, itching, and swelling of inflamed veins in the rectal area, making sitting and daily movement more comfortable.
  • Anorectal inflammation: Sufrate LA Cream calms irritated and inflamed tissues in the anal canal, helping to reduce discomfort during and after bowel movements.

Key Benefits

Sufrate LA Cream helps relieve pain and discomfort associated with anal fissures, haemorrhoids, and other painful rectal conditions.

The following are the benefits of Sufrate LA Cream:

  • Helps relieve pain, burning, and irritation in the affected area.
  • Reduces discomfort during bowel movements.
  • Supports healing of damaged rectal tissue by forming a protective barrier.
  • Helps reduce the risk of bacterial infection in affected tissues.
  • Promotes faster healing and recovery of anal fissures and related conditions.
  • Improves comfort during sitting, walking, and other daily activities.
Side effects of Sufrate LA Cream 30 gm
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Wash your hands thoroughly with soap and water before and after application.
  • Gently clean and dry the anal area before applying the medication.
  • If using the applicator provided, clean it thoroughly before use. Apply a small amount of the gel to the nozzle to lubricate it.
  • Gently insert the applicator into the anus and squeeze the tube to apply the prescribed amount of gel. Alternatively, if instructed by your doctor, apply a small amount to the external area using your finger.
  • Do not insert the applicator too deeply or force it if you feel resistance or severe pain.
  • Wash the applicator thoroughly with warm water and soap after each use, and recap the tube tightly.

How Sufrate LA Cream Works

Sufrate LA Cream combines three distinct active components to address pain, infection, and tissue damage simultaneously: • Lidocaine: It is a local anaesthetic that works by temporarily blocking the pathway of pain signals along the nerves. It numbs the applied area, providing rapid and direct relief from intense pain, itching, and burning. • Metronidazole: It is an antibacterial agent that suppresses anaerobic bacterial growth in the affected area, helping reduce the risk of secondary infection in open fissures or wounds. It also has mild direct and indirect anti-inflammatory effects, which may contribute to symptom relief in anorectal conditions. • Sucralfate: It is a mucosal protectant that binds directly to the proteins on the surface of raw, ulcerated skin. It forms a physical, protective barrier that shields the healing tissues from stool, friction, and local irritants during bowel movements.
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Alcohol

Caution

Interaction of Sufrate LA Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Sufrate LA Cream.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Sufrate LA Cream is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Sufrate LA Cream is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Safe if prescribed

Sufrate LA Cream usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of Sufrate LA Cream in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Sufrate LA Cream in patients with kidney problems, please consult a doctor.

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Children

Caution

Sufrate LA Cream should be used in children only if prescribed by a doctor.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Sufrate LA Cream in elderly patients. Please consult your doctor.

What if I have taken an overdose of Sufrate LA Cream

An overdose of this rectal medication is unlikely when used as directed. However, if the medication is accidentally swallowed or if you experience unusual symptoms like severe dizziness or confusion, seek immediate medical attention or contact a poison control center.

Diet & Lifestyle Advise

  • Increase dietary fibre: Eat more whole grains, fruits, vegetables, and legumes to soften stools and prevent constipation, which reduces pressure on the anal canal.
  • Stay well-hydrated: Drink plenty of water throughout the day to keep your bowel movements soft and easy to pass.
  • Avoid straining: Do not strain or hold your breath during bowel movements, as this increases pressure on the rectal veins and can worsen fissures and haemorrhoids.
  • Take sitz baths: Soak your pelvic area in warm water for 15 to 20 minutes two or three times a day to soothe the area, improve blood flow, and relax the anal sphincter muscle.
  • Maintain gentle hygiene: Avoid using harsh, scented soaps or rough dry toilet paper. Use wet wipes or a bidet to clean the area gently after bowel movements.

Health Queries

An anal fistula has been troubling me for nearly 10 years, and pus still comes out from the area from time to time. I would like to know if there is any medicine or treatment that can help reduce this problem without surgery?

Vikas Singh

Vikas Singh

M Pharmacy

An anal fistula that has continued for nearly 10 years with repeated pus discharge usually means the tunnel inside the skin has remained active and is not healing completely. This condition may improve temporarily, but it often comes back because the infection source inside is still present. Medicines or treatment should be taken only if advised or prescribed by your doctor. Warm sitz baths, good hygiene, avoiding constipation, and eating fibre-rich foods may help reduce discomfort and irritation. Drinking enough water and avoiding straining during bowel movements can also make symptoms easier to manage. Antibiotics or other medicines may sometimes reduce swelling or infection for a short time, but they usually do not remove the fistula completely. In long-standing fistulas, permanent healing without surgery is often difficult because the tract remains inside the tissue. Some minimally invasive procedures may be possible depending on the fistula type, so proper examination by a colorectal surgeon is important. Please seek medical care if pain, swelling, fever, or pus discharge becomes severe or frequent.

There is a fistula near my anus, and sometimes it becomes painful with swelling and pus coming out. On some days, it feels normal, but the problem keeps coming back again. Is there any treatment that can help me without surgery?

Vikas Singh

Vikas Singh

M Pharmacy

A fistula near the anus usually develops after an infection or abscess in that area. It can cause swelling, pain, pus discharge, irritation, or repeated infections that improve for some time and then return again. Since your symptoms keep coming back, it suggests that the underlying tract may still be present inside. Medicines/treatment should be taken only if advised or prescribed by your doctor. In some mild cases, symptoms can temporarily improve with antibiotics, pain relief medicines, warm sitz baths, proper hygiene, and avoiding constipation, but these measures often do not remove the fistula completely. Keeping the area clean and dry and eating fibre-rich foods with enough water may help reduce discomfort. Avoid straining during bowel movements and maintain regular toilet habits. Many anal fistulas eventually require proper medical procedures because the tract inside usually does not close permanently on its own. Please consult a doctor if you develop fever, severe pain, increasing swelling, heavy pus discharge, or difficulty passing stool, as delayed treatment may worsen the infection.

I have been dealing with an anal fistula for the last 5 years, and the problem still keeps coming back. I tried many homoeopathic medicines, but did not get any relief from them. Is there any effective treatment available that can help without surgery?

Vikas Singh

Vikas Singh

M Pharmacy

An anal fistula that has been present for 5 years and keeps returning usually means the infection tract inside has not healed completely. This condition often causes repeated swelling, pain, pus discharge, and temporary relief before the symptoms come back again. Homoeopathic medicines may help some people feel temporary comfort, but persistent fistulas usually need proper medical evaluation to understand the exact cause and severity. Medicines/treatment should be taken only if advised or prescribed by your doctor. Keeping the area clean, taking warm sitz baths, drinking enough water, and eating fibre-rich foods may help reduce irritation and discomfort. Avoid constipation and straining during bowel movements because this can worsen pain and swelling. Good hygiene can reduce repeated infections, but it may not permanently close the fistula tract. In long-standing cases, surgery or minimally invasive procedures are often considered the most effective options. Please consult a doctor, especially if you develop fever, severe pain, heavy discharge, or increasing swelling.
health query

Have a query?

How Soon It Starts Working

  • The time required for Sufrate LA Cream to start to work: The time required for Sufrate LA Cream to show its action is unknown.
  • The time for which the effects of Sufrate LA Cream last: The duration of action for Sufrate LA Cream is unknown.

What if you forget to take Sufrate LA Cream

If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply a double amount to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check the tube before use: Inspect the tube before each use. Do not use the gel if the seal is broken or if the product has changed colour or appearance.
  • Avoid contact with sensitive areas: Keep this medicine away from your eyes, nose, and mouth. If it accidentally gets into these areas, rinse thoroughly with cool water.
  • Do not share the medicine: Do not share this medicine or its applicator with anyone else. Sharing can spread infections.
  • Avoid using other rectal medicines: Do not use other rectal creams, ointments, or suppositories at the same time unless your doctor tells you to.
  • Monitor your symptoms: Talk to your doctor if your symptoms do not start to improve after 1 to 2 weeks of regular use.

Drug-Drug Interactions

verifiedApollotooltip
  • Other local anaesthetics (e.g., lidocaine, benzocaine): Combining Sufrate LA Cream with other local numbing agents may increase the risk of systemic side effects, such as numbness or dizziness.
  • Oral antibacterial agents (e.g., metronidazole): If you are taking oral antibiotics of the same class, the risk of side effects like nausea or metallic taste may slightly increase.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid consuming alcohol while using this medication, as the antibacterial component may interact with alcohol, causing nausea, headaches, or rapid heart rate, even with low rectal absorption.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANORECTAL PREPARATIONS]

FAQs

Sufrate LA Cream is used in the treatment of anal fissures (small tear in the anus lining), fistula (abnormal skin opening near the anus)Â and piles (inflamed and swollen veins in the rectum).
Sufrate LA Cream contains Lidocaine, Metronidazole and Sucralfate. Lidocaine is a local anaesthetic that decreases pain sensation by preventing pain signals transmission from nerves to the brain. Metronidazole is an antibiotic that minimises the spread of the bacterial infection around the anus skin region due to swelling and inflamed veins. Sucralfate is a protectant that works by forming a protective layer over the affected area of skin and prevents pain, irritation or burning sensation in the anus. Thereby, promotes healing of anus skin and formation of new healthy skin.
Yes, Sufrate LA Cream may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor. Also, avoid using and consult a doctor if you experience increased irritation or redness.
You are recommended to avoid foods rich in oil content and spicy foods for effective results while taking Sufrate LA Cream.
Yes, Sufrate LA Cream provides relief from pain caused by an anal fissure. Sufrate LA Cream contains lidocaine, a local anaesthetic that decreases pain sensation by causing numbness around the affected area.
Do not stop using Sufrate LA Cream without consulting your doctor, even if you find symptomatic relief, as discontinuing suddenly may worsen the condition. Therefore, complete the full course of Sufrate LA Cream as your doctor has prescribed it, and if you experience any difficulty while using Sufrate LA Cream, please consult your doctor.
Sufrate LA Cream is not addictive in nature.
No, Sufrate LA Cream should not be used for broken skin, open wounds or cuts.
Sufrate LA Cream is primarily formulated for external anal fissures and painful external haemorrhoids. If you have internal haemorrhoids, talk to your doctor to determine if this application or a different treatment is right for you.
Sufrate LA Cream should only be used during pregnancy if your doctor determines that the benefits outweigh the potential risks. Talk to your doctor to discuss your options safely.
Typically, it is applied once or twice daily, especially after a bowel movement or before bedtime. However, you must follow the exact schedule prescribed by your doctor.
This medication is generally meant for short-term relief and healing of acute conditions. Using it for extended periods without medical supervision can lead to skin thinning or increased absorption of the active ingredients. Talk to your doctor before extending use.
If your fissure or haemorrhoid is bleeding heavily, you should consult your doctor before applying Sufrate LA Cream. They will evaluate the severity of the bleeding and confirm if this treatment is appropriate for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.5938 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.925 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Lidocaine Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Sucralfate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Madsen JR, Laursen LS, Lauritsen K Kronisk inflammatorisk tarmsygdom [Chronic inflammatory bowel disease]. Nord Med. 1992;107(10):254-60Check here
  6. Williams, LaVonn A. Compounding with sucralfate for the treatment of external wounds. International Journal of Pharmaceutical Compounding. February 2009. [Accessed on 21st June 2022]Check here
  7. Lohsiriwat, Varut and Romyen Jitmungngan. Strategies to Reduce Post-Hemorrhoidectomy Pain: A Systematic Review. Medicina. March 2022. [Accessed on 21st June 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

ESKAG PHARMA PVT. LTD., AG-112, SECTOR-II, SUITE NO.804 & 805, BAISHAKHI, SALT LAKE CITY, KOLKATA-700091
Other Info - SUF0014

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