Sulfazee 1000 Tablet 15's
MRP ₹248.55
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₹37.3 Cashback (15%)
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About Sulfazee 1000 Tablet 15's
Sulfazee 1000 Tablet 15's is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in children and adults.
Sulfazee 1000 Tablet 15's contains sulfasalazine, which works by inhibiting the formation of a chemical known as prostaglandins, which control pain and inflammation.
In some cases, you may experience common side effects like a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.
Avoid taking Sulfazee 1000 Tablet 15's if you are allergic to it. Sulfazee 1000 Tablet 15's can lower your sperm count, leading to a temporary decrease in male fertility. In this case, you can speak to your doctor. Your doctor might arrange a blood test before you start taking Sulfazee 1000 Tablet 15's. Inform your doctor if you are pregnant or are breastfeeding before taking Sulfazee 1000 Tablet 15's.
Uses of Sulfazee 1000 Tablet 15's
Sulfazee 1000 Tablet 15's is used in the treatment of Ulcerative colitis, Crohn's disease, Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, and Juvenile idiopathic arthritis. The detailed uses of Sulfazee 1000 Tablet 15's are as follows:
- Ulcerative Colitis Treatment: Sulfazee 1000 Tablet 15's treats ulcerative colitis by reducing inflammation and healing the lining of the gut, relieving symptoms like diarrhoea and abdominal pain.
- Rheumatoid Arthritis Treatment: Sulfazee 1000 Tablet 15's used to slow disease progression and provide relief from joint pain, stiffness, and swelling in rheumatoid arthritis.
- Juvenile Idiopathic Arthritis: Sulfazee 1000 Tablet 15's helps to treat juvenile idiopathic arthritis in children by reducing joint inflammation, relieving pain and stiffness, and improving mobility and quality of life.
- Ankylosing Spondylitis Treatment: Sulfazee 1000 Tablet 15's alleviates pain and stiffness in ankylosing spondylitis by reducing spinal inflammation and improving mobility.
- Crohn's Disease Treatment: Sulfazee 1000 Tablet 15's helps manage Crohn's disease by controlling inflammation, alleviating symptoms, and improving gut health.
- Psoriatic Arthritis Treatment: Sulfazee 1000 Tablet 15's provides relief from joint pain, swelling, and skin symptoms associated with psoriatic arthritis.
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Directions for Use
- Sulfazee 1000 Tablet 15's should be taken after meals.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Sulfazee 1000 Tablet 15's as a whole with a glass of water.
- Do not crush, break, or chew it.
Medicinal Benefits
- Sulfazee 1000 Tablet 15's works by reducing the inflammation in the colon.
- It inhibits the formation of a chemical, prostaglandin, which controls inflammation. Together, they help in reducing the inflammation at all the sites like joints, skin, and bowel (intestines),
- This medicine treats a wider range of joint, skin and bowel diseases, including ulcerative colitis, Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis.
- Sulfazee 1000 Tablet 15's is not a painkiller. Rather, it is an anti-inflammatory.
How Sulfazee 1000 Tablet 15's Works
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What if I have taken an overdose of Sulfazee 1000 Tablet 15's
Drug Warnings
- Do not use Sulfazee 1000 Tablet 15's if you are allergic to any of its components.
- Sulfazee 1000 Tablet 15's treatment is generally considered to be safe during pregnancy, but its usage in pregnant mothers should be discussed with the doctor if planning for pregnancy.
- This medication should be avoided in breastfeeding mothers, as it passes into the milk and causes jaundice and brain problems in infants less than 2 years of age.
- Tell your doctor if you have an allergy to any other sulfa drugs (sulfonamide antibiotics), as it may cause serious skin allergies like urticaria and Stevens-Johnson syndrome.
- In men, an intake of Sulfazee 1000 Tablet 15's may lower the sperm count, which improves after stopping this medicine.
- Tell your doctor if you have asthma, wheezing, fever, breathing difficulties, a sudden severe skin rash, unusual bleeding, sore throat, fever, unexplained bruising, or any other symptoms of infection.
- Use of Sulfazee 1000 Tablet 15's may change the colour of your urine, contact lenses, and tears to yellow/orange and even make your skin more sensitive to the sunlight. But, this is normal, harmless, and nothing to worry about.
- You may have low folic acid in pregnancy while taking Sulfazee 1000 Tablet 15's, so your doctor might prescribe you iron or folic acid supplements.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Cidofovir with Sulfazee 1000 Tab can increase the risk or severity of kidney problems.
How to manage the interaction:
Taking Sulfazee 1000 Tab with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Taking tacrolimus with Sulfazee 1000 Tab will have an additive effect and may increase the risk of kidney problems.
How to manage the interaction:
Although taking tacrolimus and Sulfazee 1000 Tab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
The combined use of Sulfazee 1000 Tab and Tenofovir alafenamide can increase the risk or severity of of kidney problems.
How to manage the interaction:
Taking Sulfazee 1000 Tab and tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Sulfazee 1000 Tab with Ropivacaine can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).
How to manage the interaction:
Although taking Ropivacaine and Sulfazee 1000 Tab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of teriflunomide with Sulfazee 1000 Tab can increase the risk or severity of side effects.
How to manage the interaction:
Although taking Teriflunomide and Sulfazee 1000 Tab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as paleness, fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Combining Sulfazee 1000 Tab with Lidocaine can increase the risk of methemoglobinemia (a rare red blood cell disorder in which too little oxygen is delivered to the cells).
How to manage the interaction:
Co-administration of Sulfazee 1000 Tab with Lidocaine can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
Coadministration of bupivacaine and Sulfazee 1000 Tab may result in methemoglobinemia, an uncommon disorder that lowers the blood's ability to carry oxygen, which can induce oxygen deprivation in tissues and essential organs.
How to manage the interaction:
Although taking bupivacaine and Sulfazee 1000 Tab together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Dicoumarol together with Sulfazee 1000 Tab may increase the risk or severity of bleeding. The risk increases in patients with a history of liver or kidney disorders.
How to manage the interaction:
There may be a possibility of interaction between Sulfazee 1000 Tab and Dicoumarol, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness call a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Sulfazee 1000 Tab with Procaine can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).
How to manage the interaction:
Although taking Procaine and Sulfazee 1000 Tab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Human immunoglobulin with Sulfazee 1000 Tab may increase the risk or severity of kidney problems.
How to manage the interaction:
Co-administration of Human immunoglobulin with Sulfazee 1000 Tab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- It is advised to drink plenty of water to prevent the occurrence of kidney stones.
- Take low fibre foods such as white rice, white pasta, bread, egg, fish, tofu, butter, etc. to avoid triggering ulcerative colitis.
- Exercise regularly to suppress inflammation in the body.
- Manage stress by doing meditation and deep breathing exercises.
- Eat smaller meals to avoid pain in the stomach.
- Avoid foods that can increase or worsen ulcerative colitis such as milk, milk products, raw fruits and vegetables, beans, spicy foods, popcorn, artificial sweeteners, nuts, seeds, and fatty foods.
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Alcohol
Unsafe
It is not recommended to consume alcohol while taking Sulfazee 1000 Tablet 15's to avoid unpleasant side-effects.
Pregnancy
Consult your doctor
Sulfazee 1000 Tablet 15's should be recommended in pregnancy only if required. In case, if prescribed to a pregnant woman, it is advised to increase the folate supplementation after consulting your doctor.
Breast Feeding
Unsafe
Sulfazee 1000 Tablet 15's is excreted in breastmilk and is not recommended especially if the baby is premature or is at the risk of jaundice. It might cause kernicterus (excessive levels of bilirubin in the blood) in the new-born.
Driving
Safe if prescribed
Sulfazee 1000 Tablet 15's does not affect the ability to drive. However, if you feel drowsy after taking Sulfazee 1000 Tablet 15's, it is advised not to drive.
Liver
Unsafe
Sulfazee 1000 Tablet 15's is not recommended to use in patients with a history of liver diseases. In other people, rarely, it can cause hepatitis (inflammation of the liver).
Kidney
Unsafe
Sulfazee 1000 Tablet 15's is not recommended to use in patients with a history of kidney diseases. In other people, rarely it can cause inflammation of the kidneys.
Children
Consult your doctor
Sulfazee 1000 Tablet 15's should be advised in children only if prescribed by a child specialist.
Heart
Please consult your doctor before using Sulfazee 1000 Tablet 15's if you have pre-existing heart problems. Your doctor will prescribe Sulfazee 1000 Tablet 15's if the benefits outweigh the risks.
Geriatrics
Caution
Sulfazee 1000 Tablet 15's should be used under caution in geriatric patients as it can lead to serious side effects.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
- https://www.uptodate.com/contents/sulfasalazine-and-the-5-aminosalicylates-beyond-the-basics#:~:text=How%20it%20works%20%E2%80%94%20Sulfasalazine%20acts,control%20of%20pain%20and%20inflammation.
- https://www.gwh.nhs.uk/media/190766/sulphaslazine2.pdf
- https://www.drugs.com/drug-interactions/sulfasalazine.html
- https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwiV06S7guvsAhVAzDgGHZbsBPUQFjACegQIARAC&url=https%3A%2F%2Fwww.rheumatology.org%2FPortals%2F0%2FFiles%2FSulfasalazine-Azulfidine-Fact-Sheet.pdf&usg=AOvVaw3bdBuZJ3NTnYctOyiWUJZQ
