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compositionComposition:AMISULPRIDE-300MG
prescription
Prescription Medicine
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$anem is used to treat mental health conditions such as schizophrenia. It helps improve abnormal thoughts, hallucinations, mood changes, and behavioural problems by balancing certain chemical messengers in the brain, thereby improving mental stability and daily functioning.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMISULPRIDE-300MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sulpra-300 Tablet

Sulpra-300 Tablet is an oral prescription medication used to manage and treat symptoms of schizophrenia and other psychotic conditions. It works by restoring the balance of specific natural chemicals in your brain. By targeting these chemical pathways, it helps improve your thinking, mood, and daily emotional stability.

To get the best results, you must take Sulpra-300 Tablet consistently every day, exactly as directed by your healthcare provider. This medicine is typically taken once or twice daily, and it is best taken before meals because food can change how your body absorbs it. Incorporating regular moderate exercise, maintaining a structured routine, and eating a balanced diet can also support your treatment and improve your overall well-being.

While taking Sulpra-300 Tablet , some people may experience common side effects such as drowsiness, dry mouth, or mild weight gain. Most of these effects are manageable, but you must contact your doctor immediately if you experience serious symptoms like severe muscle stiffness, a sudden high fever, or rapid breathing. These can be signs of rare but serious reactions that need immediate medical evaluation.

You should talk to your doctor before starting this medicine if you have a history of kidney disease, Parkinson's disease, epilepsy, or heart rhythm problems. Do not take this if you have a prolactin-dependent tumour (such as breast cancer), a rare adrenal gland tumour called phaeochromocytoma, or if you are under the age of 15.

This medication can interact with alcohol, which can significantly increase drowsiness, and with other medicines that affect your heart rhythm. If you are pregnant, breastfeeding, or are an older adult, you should consult your healthcare provider to discuss the risks and benefits before starting treatment.

Uses of Sulpra-300 Tablet

Sulpra-300 Tablet is used to manage and treat symptoms of schizophrenia and other psychotic conditions. The detailed uses of Sulpra-300 Tablet are as follows:

  • Schizophrenia: Sulpra-300 Tablet helps reduce both 'positive' symptoms (like hallucinations, delusions, and unusual thoughts) and 'negative' symptoms (like lack of motivation, emotional flatness, and social withdrawal) by balancing chemical messengers in the brain.
  • Acute Psychotic Episodes: During a sudden worsening of psychosis, this medication works to quickly stabilise brain activity, helping to bring back calm and clear thinking.
     

Key Benefits

By helping to restore chemical balance in the brain, Sulpra-300 Tablet provides practical, real-world relief that allows you to feel more like yourself again. This support can make a major difference in how you manage your day-to-day life.

  • Clears Distressing Thoughts: It reduces the intensity of voices, hallucinations, and confused thinking, allowing you to focus better on your daily tasks.
  • Improves Social Interaction: It helps ease emotional flatness and social withdrawal, making it easier for you to connect with family, friends, and your community.
  • Supports Long-Term Stability: Taking this medicine consistently helps prevent symptoms from returning, reducing the need for sudden hospital visits or emergency care.
  • Restores Motivation: By addressing the negative symptoms of schizophrenia, it helps you regain the energy and interest needed to participate in activities you enjoy.
     
Side effects of Sulpra-300 Tablet
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Regularly brush your tongue and teeth to prevent Excessive Saliva Production.
  • Avoid eating foods high in sugar or acid since these foods might increase saliva production, which increases the Excessive Saliva Production.
  • Keep your head up straight and maintain proper posture to prevent saliva from collecting in your mouth.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.

Directions for Use

  • Sulpra-300 Tablet can be taken before meals or as advised by your doctor.
  • Take Sulpra-300 Tablet twice daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow the medicines as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Sulpra-300 Tablet Works

Amisulpride, the active ingredient in Sulpra-300 Tablet , works by regulating the activity of a chemical messenger in the brain called dopamine. Dopamine is essential for transmitting signals related to thinking, mood, and perception. In conditions like schizophrenia, dopamine pathways can become overactive in some parts of the brain and underactive in others, causing a range of distressing symptoms. This medication acts as a selective regulator of dopamine receptors. At lower doses, it preferentially blocks presynaptic receptors, which actually boosts dopamine signals in areas of the brain where they are too low; this helps relieve symptoms like lack of interest, low energy, and social isolation. At higher doses, it blocks postsynaptic receptors to calm excess dopamine activity in areas where it is overactive, which controls hallucinations and disorganised thoughts. This dual approach helps restore a healthy balance to your brain chemistry.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Sulpra-300 Tablet as it may lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Sulpra-300 Tablet should not be taken by pregnant women. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Sulpra-300 Tablet is unsafe and should not be taken by breastfeeding mothers. Consult your doctor for further advice.

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Driving

Caution

Sulpra-300 Tablet may cause dizziness, drowsiness and uncontrolled movements. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Take Sulpra-300 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. However, Sulpra-300 Tablet is not recommended for patients with severe liver disease. Inform your doctor immediately if you experience fatigue, loss of appetite, nausea, vomiting, abdominal pain or yellow discolouration of the eyes or skin.

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Kidney

Caution

Sulpra-300 Tablet should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustments and regular monitoring of electrolytes may be required as it may alter electrolyte levels in the body.

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Children

Unsafe

Sulpra-300 Tablet should not be given to children, as its safety and effectiveness have not been established.

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Heart

Caution

Sulpra-300 Tablet may be used in patients with heart disease if prescribed by a physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Sulpra-300 Tablet should be used with caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Sulpra-300 Tablet

If you or someone else takes too much of this medicine, seek immediate medical attention right away. Symptoms of an overdose may include extreme sleepiness, severe shaking, muscle stiffness, or low blood pressure that makes you feel faint.

Diet & Lifestyle Advise

  • Eat a balanced, nutrient-dense diet: Because this medication can sometimes cause weight gain or metabolic changes, focus on eating plenty of vegetables, fruits, whole grains, and lean proteins while limiting sugary foods.
  • Stay well hydrated: Drink water regularly throughout the day to help relieve dry mouth. Sucking on sugar-free ice chips can also help.
  • Limit caffeine: High amounts of caffeine from coffee, tea, or energy drinks can worsen anxiety and interfere with your sleep. Try to limit your caffeine intake, especially in the afternoon.
  • Avoid alcohol completely: Alcohol can dangerously interact with this medicine, worsening drowsiness, dizziness, and coordination issues.
  • Get regular moderate exercise: Engaging in low-impact physical activities like walking, swimming, or cycling can help manage your weight, support heart health, and boost your mood.
     
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Have a query?

How Soon It Starts Working

  • The time required for Sulpra-300 Tablet to start to work: Sulpra-300 Tablet ideally starts to show its action within 1 to 2 hours of administration.
  • The time for which the effects of Sulpra-300 Tablet last: Sulpra-300 Tablet effect lasts for 24 hours.

What if you forget to take Sulpra-300 Tablet

If you miss a dose of Sulpra-300 Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular routine. Do not take a double dose to make up for a missed one.

Storage

•Store Sulpra-300 Tablet tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister pack or container to protect them from light and moisture.

Drug Warnings

  • Do not stop taking Sulpra-300 Tablet suddenly: Stopping your medication abruptly can cause withdrawal symptoms or lead to a rapid return of your illness. Always consult your doctor, who will guide you in gradually reducing your dose.
  • Stand up slowly: This medicine can cause your blood pressure to drop when you stand up quickly, leading to dizziness or fainting. Rise slowly from sitting or lying down to help prevent this.
  • Be cautious with hot weather: This medication can make it harder for your body to regulate its temperature. Stay cool, drink plenty of fluids, and avoid overexerting yourself in extreme heat to prevent heat stroke.
  • Avoid driving if you feel sleepy: Since drowsiness is a common side effect, do not drive, ride a bicycle, or operate heavy machinery until you are certain how this medicine affects your alertness.
  • Keep up with regular check-ups: Your doctor may order routine blood tests to monitor your prolactin levels, blood sugar, and kidney function, as well as periodic heart tracings (ECGs) to ensure the medication remains safe for you.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Heart rhythm medications (such as amiodarone, sotalol, and quinidine): Taking these with Sulpra-300 Tablet can increase the risk of serious, irregular heartbeats.
  • Central nervous system depressants (like sleeping pills, anti-anxiety medicines, or strong painkillers): Combining these can cause extreme drowsiness and slowed breathing.
  • Blood pressure-lowering medicines: Sulpra-300 Tablet can enhance the effects of these medications, which may cause your blood pressure to drop too low and make you feel dizzy.
  • Parkinson's disease medications (such as levodopa): These medicines can block the action of Sulpra-300 Tablet , making both drugs less effective.
     
AmisulprideCisapride
Critical
AmisulprideDronedarone
Critical

Drug-Drug Interactions

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AmisulprideCisapride
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sulpra-300 Tablet with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideDronedarone
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet with Dronedarone can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpra-300 Tablet with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideMesoridazine
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet with Mesoridazine can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpra-300 Tablet with Mesoridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulpridePimozide
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Pimozide with Sulpra-300 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Sulpra-300 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideMetoclopramide
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Metoclopramide with Sulpra-300 Tablet may increase the risk or severity of side effects.

How to manage the interaction:
Taking Sulpra-300 Tablet with Metoclopramide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideSaquinavir
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Saquinavir with Sulpra-300 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpra-300 Tablet with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AmisulprideGrepafloxacin
Critical
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet with Grepafloxacin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Sulpra-300 Tablet with Grepafloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
AmisulprideZiprasidone
Critical
How does the drug interact with Sulpra-300 Tablet:
Co-administration of Ziprasidone with Sulpra-300 Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Sulpra-300 Tablet but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmisulprideTacrolimus
Severe
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet together with tacrolimus can increase the risk of an irregular heart rhythm and can lead to severe side effects.

How to manage the interaction:
Although taking Sulpra-300 Tablet and tacrolimus together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting a doctor.
AmisulprideDasatinib
Severe
How does the drug interact with Sulpra-300 Tablet:
Taking Sulpra-300 Tablet with Dasatinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Sulpra-300 Tablet along with Dasatinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking this medicine, as it can worsen drowsiness and significantly impair your coordination and judgement.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Sulpra-300 Tablet is used to treat long-term (chronic) schizophrenia.
Sulpra-300 Tablet contains amisulpride, which works by balancing dopamine activity in the brain. It improves thinking, mood, and behaviour while reducing abnormal mental symptoms.
Sulpra-300 Tablet can be used to treat psychotic disorders like schizophrenia, bipolar disorder and depression. However, you should not take this medication without a doctor's advice.
Sulpra-300 Tablet may affect fertility as it may cause hyperprolactinemia (excessive levels of prolactin hormone in the blood) resulting in amenorrhea (absence of menstrual periods), anovulation (lack of egg release) and impaired fertility.
You are not recommended to stop taking Sulpra-300 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Sulpra-300 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Sulpra-300 Tablet , please consult your doctor so that the dose may be gradually reduced.
Sulpra-300 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Sulpra-300 Tablet .
Take Sulpra-300 Tablet with caution in patients with diabetes, as it may increase the risk of having diabetes. It is advised to monitor your blood sugar levels regularly while taking Sulpra-300 Tablet .
Sulpra-300 Tablet is not recommended for children as the safety and effectiveness have not been established.
Sulpra-300 Tablet should be used with caution and only if prescribed by the doctor in elderly patients due to the possible risk of low blood pressure and sedation.
Sulpra-300 Tablet should be used in patients with kidney diseases only when prescribed by a doctor. Dose adjustment and regular electrolyte monitoring may be required, as Sulpra-300 Tablet may alter electrolyte levels.
Sulpra-300 Tablet may cause sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.
Sulpra-300 Tablet should be taken at the same time daily or as prescribed by the doctor.
Sulpra-300 Tablet modulates certain chemical messengers (dopamine D2) in the brain, which helps regulate mood and behaviour.
No, Sulpra-300 Tablet is not indicated for anxiety. It is used to treat schizophrenia and postoperative nausea and vomiting.
Do not take Sulpra-300 Tablet if you are allergic (hypersensitive) to amisulpride or any other ingredients present in this medicine or have a medical history of prolactin-dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), or pituitary tumour.
No, Sulpra-300 Tablet has no habit-forming tendency and is not addictive.
Withdrawal symptoms of Sulpra-300 Tablet are nausea, vomiting, difficulty sleeping, sweating, extreme restlessness, abnormal movements, or muscle stiffness.
Sulpra-300 Tablet may cause side effects such as dry mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to remain still), parkinsonism, and increased blood prolactin levels. Most of these side effects of Sulpra-300 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, consult your doctor immediately.
Some people may experience mild weight gain or an increased appetite while taking this medicine. Eating a balanced diet and exercising regularly can help manage these effects. If you are concerned about weight changes, talk to your doctor or a dietitian.
This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides that the benefit to you outweighs the risk to your baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor immediately.
Drowsiness is common, especially when you first start taking this medicine. Avoid driving or operating machinery if you feel tired. Taking your dose at a specific time of day may help, but always talk to your doctor before changing your dosing routine.
You can consume moderate amounts of caffeine, but large amounts can worsen anxiety and interfere with your sleep. Try to monitor how caffeine affects you and limit your intake if needed. Talk to your doctor for personalised dietary advice.
This medicine can make it harder for your body to regulate its temperature, making you more sensitive to extreme heat. It is important to stay cool, drink plenty of water, and avoid heavy exercise in hot weather. Talk to your doctor if you experience signs of heat exhaustion.

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Country of origin

India

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - SUL0200

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