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Composition:HYDROCHLOROTHIAZIDE-12.5MG+METOPROLOL-50MG

Prescription Medicine

SUPERMET H TABLET is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Metoprolol and Hydrochlorothiazide, which work by relaxing the blood vessels. Thus, it helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thereby, it lowers fluid overload, improves blood flow, lowers blood pressure and reduces the future risk of a heart attack and stroke. It may cause side effects such as nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in the blood.

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+METOPROLOL-50MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About SUPERMET H TABLET

SUPERMET H TABLET is a prescription medication used to treat high blood pressure (hypertension). By keeping blood pressure within normal levels, this medicine helps prevent long-term damage to major organs and reduces your risk of severe heart complications. Keeping your blood pressure under control is an active, ongoing process that requires careful management.

For this medicine to work effectively, you need to take it consistently and exactly as prescribed, typically once daily. It is best taken with or immediately after a meal to help your body absorb the active ingredients properly. Combining this daily treatment with healthy dietary choices, like reducing sodium, and engaging in moderate physical activity can significantly improve your results.

While taking SUPERMET H TABLET, you may experience some mild side effects like dizziness or feeling tired as your body adjusts. However, you must contact your doctor immediately if you notice serious symptoms such as an unusually slow heart rate, severe breathing difficulties, or sudden, unexplained weight gain. Keeping track of how you feel is an important part of your therapy.

Do not take this if you have severe asthma, a very slow pulse, serious heart block, or if you are unable to pass urine. It is vital to talk to your doctor before starting this medicine if you have a history of diabetes, thyroid issues, or liver or kidney disease. Your doctor will evaluate these conditions to make sure this treatment is safe for your body.

This medicine can interact with alcohol, smoking, and certain other drugs like pain relievers or other blood pressure therapies, which can lead to excessive dizziness or reduced effectiveness. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for your specific situation.

Uses of SUPERMET H TABLET

SUPERMET H TABLET is used in the treatment of high blood pressure (hypertension). The detailed uses of SUPERMET H TABLET are as follows:

High blood pressure (hypertension): SUPERMET H TABLET is primarily prescribed to lower high blood pressure, helping your blood vessels relax and reducing the workload on your cardiovascular system.
Prevention of heart complications: By maintaining healthy blood pressure levels, this medication helps lower the risk of experiencing life-threatening events such as strokes and heart attacks.

Key Benefits

SUPERMET H TABLET helps lower high blood pressure and keep it under better control over time. By maintaining healthy blood pressure levels, it reduces the strain on your heart and blood vessels, helping you stay active and lowering the risk of serious health problems.

Benefits may include:

Helps effectively lower and control high blood pressure.
Reduces the risk of heart attack, stroke, and other complications of hypertension.
Supports long-term protection of the heart, kidneys, brain, and blood vessels.
Improves heart health by reducing the workload on the heart.
Promotes better treatment adherence with the convenience of a single combination tablet.

Side effects of Supermet H Tablet

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Stomach problems

Dry Mouth

Here are the steps to Dry Mouth (xerostomia) caused by medication:

Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Pain In The Stomach Or Intestines

Directions for Use

Swallow the medication whole with a full glass of water. Do not crush, chew, or break the tablet, as this can interfere with how the medicine is released.
Take this medication with or immediately after a meal to enhance absorption and reduce potential stomach irritation.
Try to take your dose at the same time every day to establish a consistent routine and keep steady levels of the medicine in your body.
Always follow your doctor's exact instructions regarding your dose, and never alter your routine without their guidance.

How SUPERMET H TABLET Works

SUPERMET H TABLET works through the combined action of two distinct active ingredients that target different systems in your body to lower blood pressure efficiently. • Metoprolol: It belongs to a group of medicines known as beta-blockers. It works by blocking certain stress hormones, like adrenaline, which slows down your heart rate and allows the heart to beat with less force. This action relaxes your blood vessels and makes it easier for blood to flow throughout your body. • Hydrochlorthiazide: It is a diuretic, often referred to as a water pill. It prompts your kidneys to filter out extra salt and water, which you then remove from your body when you urinate. Reducing the overall amount of fluid in your bloodstream lowers the pressure against your artery walls, working hand-in-hand with the first ingredient to keep your blood pressure stable.

Alcohol

Caution

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with SUPERMET H TABLET.

Pregnancy

Caution

SUPERMET H TABLET is a pregnancy category C drug. It is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast Feeding

Caution

Small amounts of SUPERMET H TABLET passes into the breast milk. However which is not enough to cause any problems to your baby. But, still, it is advisable to contact your doctor before breastfeeding your baby.

Driving

Caution

You may experience dizziness, tiredness, or blurred vision while taking SUPERMET H TABLET. So, it is not recommended to drive, use machinery, or perform other tasks.

Liver

Caution

SUPERMET H TABLET should be used with caution in patients with impaired hepatic function or progressive liver disease since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Your doctor may adjust your dose depending upon your current liver conditions.

Kidney

Caution

SUPERMET H TABLET to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

Children

Unsafe

The safety and efficacy of SUPERMET H TABLET in children have not been established. SUPERMET H TABLET is not recommended in children.

Heart

Safe if prescribed

SUPERMET H TABLET is safe for use in heart patients if recommended by the physician.

Geriatrics

Caution

SUPERMET H TABLET should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of SUPERMET H TABLET

If you suspect an overdose, seek immediate medical attention or contact emergency services right away. Signs of an overdose can include severe dizziness, fainting, an extremely slow heart rate, or severe difficulty breathing.

Diet & Lifestyle Advise

Limit your salt intake: Reduce the amount of sodium in your diet by avoiding processed foods and not adding extra salt to your meals. High sodium intake directly raises blood pressure and can counter the benefits of this medicine.
Stay moderately active: Engage in regular, low-impact exercise such as brisk walking, cycling, or swimming, which helps strengthen your heart muscle naturally.
Monitor your potassium levels: This medicine can alter the balance of potassium in your body. Discuss with your doctor whether you should increase or decrease your consumption of potassium-rich foods like bananas, spinach, and sweet potatoes.
Avoid alcohol and tobacco: Alcohol can dangerously compound the dizzying effects of this medication, while smoking damages your blood vessels and raises your cardiovascular risk.
Stand up slowly: To prevent sudden drops in blood pressure that cause dizziness, take your time when transitioning from lying down or sitting to a standing position.

Have a query?

How Soon It Starts Working

The time required for SUPERMET H TABLET to start to work: SUPERMET H TABLET ideally shows its action within 2 hours after administration.
The time for which the effects of SUPERMET H TABLET last: The effect of SUPERMET H TABLET lasts for 3 days.

What if you forget to take SUPERMET H TABLET

If you miss a dose of SUPERMET H TABLET, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose entirely and resume your regular schedule. Do not take a double dose to make up for the one you missed.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not stop taking this medicine suddenly: Abruptly discontinuing SUPERMET H TABLET can cause severe rebound high blood pressure, chest pain, or rapid heart rate. Your doctor will provide instructions on gradually decreasing your dose if you need to stop taking it.
Track your pulse regularly: Because this medicine slows down your heart rate, check your pulse frequently. If your heart rate falls below 50 beats per minute or the target set by your doctor, contact them immediately.
Monitor your blood sugar closely: If you have diabetes, be aware that this medicine can mask the typical physical warning signs of low blood sugar, such as a racing heart or tremors.
Protect your skin from the sun: One of the ingredients in this medicine can make your skin highly sensitive to sunlight. Wear protective clothing and apply broad-spectrum sunscreen when spending time outdoors.
Inform your surgeon: Always tell your surgeon, dentist, or anesthesiologist that you take SUPERMET H TABLET before any medical procedures, as it can interact with anaesthetics and other surgical medications.

Drug-Drug Interactions

Drug-Drug Interactions:

Blood Pressure Medicines or Heart Medicines (e.g., amlodipine, digoxin, isosorbide mononitrate): Taking SUPERMET H TABLET with these medications can cause your blood pressure or heart rate to fall dangerously low.
Non-steroidal Anti-inflammatory Drugs (e.g., ibuprofen, naproxen): Combining SUPERMET H TABLET with NSAIDs can decrease its effectiveness and increase your risk of kidney strain.
Diabetes Medicines (e.g., insulin, metformin, glimepiride): May interact with diabetes medications, potentially requiring adjustments to your dosing and blood sugar monitoring.
Mood stabilisers (e.g., lithium): Taking lithium alongside SUPERMET H TABLET may increase lithium levels in the body and raise the risk of lithium toxicity.

Drug-Food Interactions:

Alcohol: Drinking alcohol while on this medication can lead to a sudden, severe drop in blood pressure, resulting in intense dizziness or fainting.

Drug-Disease Interactions:

Asthma and chronic lung diseases: Patients with these conditions may be at increased risk of worsening breathing problems while taking this medication.
Diabetes: Can mask signs of low blood sugar and interfere with blood sugar management.
Gout: The water pill component may elevate uric acid levels, which can trigger painful gout flare-ups.
Kidney or liver disease: Reduced kidney or liver function can cause the drug to accumulate in your body, demanding close medical supervision.

Metoprolol + HydrochlorothiazideCisapride

Critical

Metoprolol + HydrochlorothiazideDofetilide

Critical

Drug-Drug Interactions

Metoprolol + HydrochlorothiazideCisapride

Critical

How does the drug interact with Supermet H Tablet:
Taking Metoprolol and Hydrochlorothiazide with Cisapride can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Metoprolol and Hydrochlorothiazide together with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Metoprolol + HydrochlorothiazideDofetilide

Critical

How does the drug interact with Supermet H Tablet:
Taking Metoprolol and Hydrochlorothiazide with Dofetilide can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Metoprolol and Hydrochlorothiazide together with Dofetilide is not recommended as it can possibly result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideClonidine

Severe

How does the drug interact with Supermet H Tablet:
Co-administration of Metoprolol and Hydrochlorothiazide with Clonidine may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Metoprolol, Hydrochlorothiazide and Clonidine, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact a doctor. Do not stop using any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideSaquinavir

Severe

How does the drug interact with Supermet H Tablet:
Using Metoprolol and Hydrochlorothiazide with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metoprolol, Hydrochlorothiazide and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideAtazanavir

Severe

How does the drug interact with Supermet H Tablet:
Co-administration of Metoprolol and Hydrochlorothiazide with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metoprolol and Hydrochlorothiazide with Atazanavir, it can be taken if prescribed by the doctor. Consult a doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideAmiodarone

Severe

How does the drug interact with Supermet H Tablet:
Co-administration of Metoprolol and Hydrochlorothiazide together with Amiodarone may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Metoprolol and Hydrochlorothiazide with Amiodarone, it can be taken if advised by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideTizanidine

Severe

How does the drug interact with Supermet H Tablet:
The combined use of Metoprolol and Hydrochlorothiazide with Tizanidine can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Metoprolol and Hydrochlorothiazide together with Tizanidine can possibly result in an interaction, but they can be taken if advised by a doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Metoprolol + HydrochlorothiazideDiltiazem

Severe

How does the drug interact with Supermet H Tablet:
Co-administration of Metoprolol and Hydrochlorothiazide with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Metoprolol, Hydrochlorothiazide and Diltiazem, you can take these medicines together if prescribed by a doctor. Consult a doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Metoprolol + HydrochlorothiazideDronedarone

Severe

How does the drug interact with Supermet H Tablet:
Co-administration of Metoprolol and Hydrochlorothiazide with Dronedarone can increase the risk of severe irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Metoprolol and Hydrochlorothiazide together with Dronedarone can possibly result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Metoprolol + HydrochlorothiazideZiprasidone

Severe

How does the drug interact with Supermet H Tablet:
Taking Metoprolol and Hydrochlorothiazide with Ziprasidone can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Metoprolol and Hydrochlorothiazide together with Ziprasidone can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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[ANTI- HYPERTENSIVES]

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Author Details

Written By

Bayyarapu Mahesh Kumar
M Pharmacy

Reviewed By

Dr Aneela Siddabathuni
MPharma., PhD

Last Updated

Jun 30, 2026 | 12:24 PM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In

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SUPERMET H TABLET

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About SUPERMET H TABLET

Uses of SUPERMET H TABLET

Key Benefits

Loose And Watery Stools

Stomach problems

Dry Mouth

Nausea

Vomiting

Constipation

Pain In The Stomach Or Intestines

Directions for Use

How SUPERMET H TABLET Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of SUPERMET H TABLET

Diet & Lifestyle Advise

How Soon It Starts Working

What if you forget to take SUPERMET H TABLET

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

All Substitutes & Brand Comparisons

Betaloc H 50 mg Tablet 10's

METO ER HT 50MG TABLET

Myoprol XL H Tablet 10's

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FAQs

What is the use of SUPERMET H TABLET?

How does SUPERMET H TABLET work?

Can I take SUPERMET H TABLET if I am diabetic?

Will I need to stop SUPERMET H TABLET before surgery?

I am suffering from asthma. Can I take SUPERMET H TABLET?

How long can SUPERMET H TABLET be taken?

Does regular intake of SUPERMET H TABLET decreases pottasium level?

Can use of SUPERMET H TABLET cause sunburn or increased photosensitivity?

Can I take SUPERMET H TABLET with food?

What are the side effects of SUPERMET H TABLET?

Can I drink alcohol while taking SUPERMET H TABLET?

How should I store SUPERMET H TABLET?

Are there any serious side effects I should look out for while taking SUPERMET H TABLET?

What should I do if I miss a dose of SUPERMET H TABLET?

Can I stop taking SUPERMET H TABLET if my blood pressure feels normal?

Can I take over-the-counter pain relievers like ibuprofen with SUPERMET H TABLET?

Why do I feel dizzy when I stand up quickly while taking SUPERMET H TABLET?

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