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  3. Tacronex Slution 15 ml

Tacronex Slution 15 ml, Pack of 1 SOLUTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tacronex Slution is used to treat atopic dermatitis (eczema). It contains Tacrolimus which works by suppressing the over-reaction of immune cells in the skin to a stimulus. This medicine may sometimes cause side effects such as itching, redness, pain, tingling or burning sensation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

TACROLIMUS-0.1%W/V

Manufacturer/Marketer :

Inex Medicaments Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Tacronex Slution

Tacronex Slution is used to treat moderate to severe atopic dermatitis (eczema). Atopic dermatitis, also known as eczema, is a common skin condition associated with inflamed and itchy skin patches. The symptoms include itchy, dry, flaky, swollen, rough and irritated skin.

Tacronex Slution contains 'Tacrolimus' that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling). 

Use Tacronex Slution as prescribed. You are advised to use Tacronex Slution for as long as your doctor has recommended it for you based on your medical condition. Some people may experience itching, burning sensation, redness, pain or skin tingling. Most of these side effects of Tacronex Slution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex Slution. Avoid alcohol consumption with Tacronex Slution as it may cause flushing (sudden reddening of face or skin that makes you feel warm and hot). Do not cover or wrap the treated area with a bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacronex Slution catches fire and burns easily.

Uses of Tacronex Slution

Tacronex Slution is used in the treatment of atopic dermatitis (eczema). The detailed uses of Tacronex Slution are as follows:

Atopic Dermatitis Treatment: Tacronex Slution is often used to manage symptoms of atopic dermatitis, providing relief for itching and inflammation associated with this skin condition.

Reducing Skin Inflammation: Tacronex Slution can also be used to reduce overall skin inflammation, whether due to allergic reactions or other inflammatory conditions.

Psoriasis Management: Tacronex Slution can be effective in treating psoriasis by reducing the scaling and redness of the skin.

Eczema Relief: Tacronex Slution may be used to alleviate the symptoms of eczema, helping to soothe irritated skin and restore moisture.

Post-Transplant Skin Care: Tacronex Slution is sometimes prescribed for patients who have undergone organ transplants to prevent skin-related complications.

Directions for Use

  • Tacronex Slution is for external use only.
  • It is usually applied twice daily or as directed by your doctor.
  • Check the label for directions before using this medicine.
  • Clean and dry the affected area of the skin. Take a small amount of Tacronex Slution on the fingertip and apply it as a thin layer on the affected area.
  • Wash your hands before and after using Tacronex Slution unless the treatment is for hands.
  • If Tacronex Slution accidentally comes into contact with the nose, mouth, eyes, or vagina, rinse with water thoroughly.

Medicinal Benefits

  • Tacronex Slution is a topical immunosuppressant (calcineurin inhibitor) containing Tacrolimus as its active ingredient, used for managing inflammatory skin conditions.
  • It is indicated for the treatment of moderate to severe atopic dermatitis (eczema) in adults and children above 2 years who do not respond adequately or are intolerant to topical corticosteroids.
  • Tacrolimus works by selectively inhibiting calcineurin, which suppresses the overactive immune response in the skin, thereby reducing inflammation, redness, swelling, and allergic reactions.
  • It provides relief from itching, skin irritation, and flare-ups, improving the appearance and comfort of affected skin areas.
  • When used as prescribed, it may help prevent further flare-ups and maintain long-term control of atopic dermatitis symptoms.

How Tacronex Slution Works

Tacronex Slution contains 'Tacrolimus' that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling).

Storage

• Store in a cool and dry place away from sunlight.• Keep Tacronex Slution out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Tacronex Slution 15 ml
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat a well-balanced diet, and avoid highly processed foods.
  • Regular exercise can help prevent ascites.
  • Maintain a healthy weight, as obesity is a risk factor for ascites.
  • Limit salt intake; try to consume no more than 2,000–4,000 milligrams of salt per day.
  • Avoid alcohol, as it can damage your liver and increase the risk of cirrhosis.
  • Practice safe sex, unprotected sex can lead to hepatitis, which can damage the liver and cause cirrhosis.
  • Get vaccinated for diseases like hepatitis, influenza, and pneumococcal.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Tacronex Slution

An overdose of Tacronex Slution is not likely to be harmful. However, the risk of overdose may result in negative consequences. If anyone has accidentally consumed the drug, get emergency medical assistance or contact your doctor immediately.

Drug Warnings

  • Tacronex Slution should not be used by individuals who are allergic to Tacrolimus or any of its ingredients. It is also contraindicated in those with severe skin infections or compromised skin barriers.
  • If you're taking other immunosuppressants, topical steroids, or medications that affect the immune system, Tacronex Slution should be used cautiously, as it may increase the risk of infections or side effects.
  • Be sure to inform your healthcare provider if you're taking antifungal medications, antibiotics, antivirals, blood pressure drugs, or vitamin E supplements, as these may interact with Tacronex Slution and affect its effectiveness or cause skin irritation.
  • Tacronex Slution should be used with caution during pregnancy and breastfeeding. Consult your doctor before using it if you're pregnant or breastfeeding, as the effects on the fetus or infant are not fully known.
  • Tacronex Slution is not recommended for children under 2 years. For children older than 2, consult your healthcare provider for appropriate use and dosage.
  • Tacronex Slution can increase sensitivity to sunlight, so it's essential to use sun protection like sunscreen and protective clothing. Avoid smoking or being near flames after applying the medication, as fabrics in contact with it may catch fire easily.

Drug-Drug Interactions

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TacrolimusMifepristone
Critical
TacrolimusDronedarone
Critical

Drug-Drug Interactions

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TacrolimusMifepristone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Mifepristone may significantly increase the blood levels of Tacronex Slution 15 ml, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
TacrolimusDronedarone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusThioridazine
Critical
How does the drug interact with Tacronex Slution 15 ml:
Combining Tacronex Slution 15 ml with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusCidofovir
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking cidofovir with Tacronex Slution 15 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusSaquinavir
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusLoperamide
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with loperamide may significantly increases the loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking loperamide with Tacronex Slution 15 ml together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
TacrolimusPosaconazole
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with posaconazole may significantly increase the blood levels of Tacronex Slution 15 ml, which may increase the risk of kidney problems, diabetes, hyperkalemia (high potassium levels in the blood), high blood pressure, irregular heart rhythm and infections.

How to manage the interaction:
Although using Posaconazole and Tacronex Slution 15 ml together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, red or irritated skin, body sores, discomfort or burning during urination, numbness or tingling, fits, dizziness, lightheadedness, fainting, and chest pain. Do not stop taking any medications without consulting a doctor.
TacrolimusStreptomycin
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with streptomycin may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Tacronex Slution 15 ml and streptomycin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
TacrolimusAdalimumab
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Adalimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Tacronex Slution 15 ml and adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacronex Slution 15 ml treatment may lead to increased Tacronex Slution 15 ml levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacronex Slution 15 ml.

Diet & Lifestyle Advise

  • Consume anti-inflammatory foods like fatty fish, flaxseeds, and walnuts to help reduce skin inflammation.
  • Avoid common food triggers such as dairy, eggs, soy, gluten, and nuts, and consider an elimination diet.
  • Drink plenty of water throughout the day to keep your skin hydrated and prevent dryness.
  • Prefer probiotic-rich foods like yoghurt and kefir to support gut health, which can improve skin condition.
  • Apply fragrance-free moisturisers regularly to maintain hydration and protect the skin’s barrier.
  • Choose mild, fragrance-free soaps, shampoos, and detergents to prevent skin irritation and allergic reactions.
  • Wear soft, breathable fabrics like cotton to minimise skin irritation; avoid wool or synthetic materials.
  • Practice stress management techniques like meditation, deep breathing, or yoga to reduce flare-ups.
  • Always consult your healthcare provider for personalised advice on managing eczema and medication use.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Tacronex Slution Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption with Tacronex Slution as it may cause skin or face to become flushed or red and feel hot.

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Pregnancy

Caution

Tacronex Slution is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before using Tacronex Slution.

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Breast Feeding

Consult your doctor

Please consult a doctor if you are a breastfeeding mother before using Tacronex Slution.

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Driving

Safe if prescribed

Tacronex Slution usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Since it is a topical medication, the absorption into the bloodstream is generally lower compared to oral medications. This means the impact on liver function is typically less significant. However, in cases of severe liver disease, caution is still recommended because there may still be some systemic absorption. It's best to consult your healthcare provider before using it, as they can assess your specific liver condition and determine if the medication is safe for you. Regular monitoring might still be advised to ensure it doesn't cause any adverse effects.

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Kidney

Consult your doctor

As Tacronex Slution is a topical medication, it has minimal systemic absorption. However, in cases of severe kidney disease, caution is advised due to the possibility of some absorption affecting kidney function. Always consult your healthcare provider before use, as they may recommend monitoring kidney function during treatment for added safety.

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Children

Caution

Tacronex Slution is not recommended for children below two years of age. For children above two years, Tacronex Slution should be used in dose and duration advised by a doctor only.

Have a query?

FAQs

Tacronex Slution is used to treat moderate to severe atopic dermatitis (eczema).

Tacronex Slution contains Tacrolimus, an immunosuppressant that works by suppressing the overreaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling).

Tacronex Slution may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.

You are recommended to avoid or limit exposure to the sun for a long time or artificial light, such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

You are not recommended to take a shower, swim or bath immediately after applying Tacronex Slution as water may wash off this medicine.

Tacronex Slution is flammable and can catch fire; hence, avoid smoking or going near naked flames after applying the ointment of tacrolimus.

You are recommended to use Tacronex Slution for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after using Tacronex Slution for two weeks, please consult a doctor.

Country of origin

INDIA

Manufacturer/Marketer address

INEX HOUSE , PLOT NO : 22 , VILLA \'A&B\', SECOND FLOOR , RAJIV STREET, KAMARAJ NAGAR,, Keelkattalai, Chennai, Tamil Nadu 600117
Other Info - TAC0080

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 31, 2025 | 12:10 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1612.pdf

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