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TANCODEP 5MG TABLET is used to treat depression. It contains Imipramine and Diazepam which work by increasing certain chemicals in the brain that produce a calming effect. In some cases, this medicine may cause side effects such as drowsiness, fatigue, confusion, dry mouth, constipation, vision problems, and loss of appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About TANCODEP 5MG TABLET

TANCODEP 5MG TABLET is a combination prescription medicine used to treat depression accompanied by anxiety, restlessness, or nervous tension. It helps by restoring the balance of certain natural chemicals in the brain, thereby improving both mood and physical symptoms of anxiety. Your doctor may prescribe this medicine when a single-ingredient treatment is not sufficient to address both conditions simultaneously.

To get the best results, you must take TANCODEP 5MG TABLET regularly and exactly as prescribed by your doctor. It is typically taken once or twice a day, with or without food. Along with this medicine, adopting a structured sleep schedule, practising relaxation techniques, and engaging in light daily exercise can significantly support your treatment progress.

While taking TANCODEP 5MG TABLET, some people may experience mild side effects like drowsiness, dry mouth, or mild constipation. If you experience severe symptoms such as a very fast heartbeat, severe dizziness, or difficulty passing urine, you should contact your doctor immediately.

Do not take this if you have a history of a recent heart attack, severe liver damage, or a specific eye condition called narrow-angle glaucoma. It is important to talk to your doctor or pharmacist about your complete medical history, especially if you have kidney issues, breathing problems, or difficulty urinating before you begin this medication.

This medicine can interact with alcohol, smoking, and other medications that cause drowsiness, which may lead to extreme tiredness or slowed breathing. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor to discuss if this medicine is safe for your specific situation. This combination requires careful specialist assessment in children and adolescents. Antidepressants may increase suicidal thoughts or behaviour in some younger people, particularly during the early stages of treatment or after dose changes, so close monitoring is essential.

Uses of TANCODEP 5MG TABLET

TANCODEP 5MG TABLET is used to manage conditions involving depression and anxiety, particularly when mood symptoms occur alongside nervous tension or restlessness. Its uses include:

  • Depression with anxiety: TANCODEP 5MG TABLET helps improve low mood, sadness, and loss of interest while simultaneously reducing feelings of nervousness, apprehension, and constant worry.
  • Anxiety neurosis: It helps manage severe, ongoing anxiety states that interfere with daily functioning by calming overactive nerve signals in the brain.

Key Benefits

TANCODEP 5MG TABLET combines an antidepressant with a benzodiazepine to address both mood and anxiety-related symptoms. Its benefits include:

  • Improves Mood Symptoms: Helps reduce persistent low mood and other symptoms associated with depression.
  • Relieves Anxiety and Tension: Helps reduce excessive anxiety, restlessness, and emotional distress, promoting a greater sense of calm.
  • Supports Better Sleep: By easing anxiety and mood-related distress, it may help improve sleep in people whose symptoms interfere with rest.
  • Improves Daily Functioning: Better control of mood and anxiety symptoms may make it easier to concentrate, maintain routines, and participate in daily or social activities.
  • Provides Combined Symptom Relief: Combines two complementary actions in a single treatment to manage coexisting mood and anxiety symptoms.
Side effects of Tancodep 5mg Tablet
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.

Directions for Use

  • Take TANCODEP 5MG TABLET on an empty stomach or as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How TANCODEP 5MG TABLET Works

TANCODEP 5MG TABLET contains imipramine and diazepam, which work together to target different pathways in the brain. The first active component, imipramine, belongs to a class of medicines called tricyclic antidepressants. It works by keeping higher levels of mood-regulating chemicals, specifically serotonin and noradrenaline, active in your brain for longer periods, which helps lift your overall mood. The second active component, diazepam, belongs to a class known as benzodiazepines. It works by enhancing the effects of a natural calming chemical in the brain called GABA. By boosting GABA, this component helps slow down overactive nerve signals, quickly easing physical tension, muscle stiffness, panic, and acute anxiety. Together, these actions provide balanced emotional support.
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Alcohol

Unsafe

Do not take alcohol while using TANCODEP 5MG TABLET as it can cause excessive drowsiness.

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Pregnancy

Unsafe

TANCODEP 5MG TABLET is not recommended for pregnant women as it may cause harmful effects to the unborn baby.

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Breast Feeding

Unsafe

TANCODEP 5MG TABLET may pass into breastmilk and cause harmful effects to the nursing baby. So, it is not recommended to use in breastfeeding mothers.

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Driving

Unsafe

TANCODEP 5MG TABLET may cause drowsiness and blurred vision, so do not drive or operate heavy machinery while using this medicine.

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Liver

Caution

TANCODEP 5MG TABLET should not be used in patients with severe liver diseases. It should be used with caution in patients with mild to moderate liver diseases, and the dose may have to be adjusted by your doctor.

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Kidney

Caution

TANCODEP 5MG TABLET should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

TANCODEP 5MG TABLET should not be used in children less than 6 years of age. In children above 6 years, this medicine should be used only if clinically needed.

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Heart

Unsafe

TANCODEP 5MG TABLET is not recommended in cardiac patients due to its adverse effects. However, if prescribed, extreme caution should be exercised.

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Geriatrics

Unsafe

TANCODEP 5MG TABLET is not safe for use in elderly patients due to its severe side effects.

What if I have taken an overdose of TANCODEP 5MG TABLET

In case of an accidental overdose, seek immediate emergency medical attention or contact a poison control centre right away. Do not wait for symptoms of illness to appear.

Diet & Lifestyle Advise

  • Eat a Fibre-Rich Diet: Drink adequate water and include fruits, vegetables, and whole grains in your diet to help manage constipation.
  • Stand Up Slowly: Rise gradually from a sitting or lying position to reduce the risk of dizziness, lightheadedness, or fainting.
  • Avoid Alcohol: Do not drink alcohol while taking TANCODEP 5MG TABLET, as it may increase severe drowsiness, impaired coordination, and the risk of dangerous breathing problems.
  • Limit Excessive Caffeine: Reduce excessive intake of coffee, tea, energy drinks, and other caffeine-containing products if they worsen anxiety, restlessness, or sleep problems.
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Have a query?

How Soon It Starts Working

The time required for TANCODEP 5MG TABLET to start to work: The time required for TANCODEP 5MG TABLET to show its action is unknown. The time for which the effects of TANCODEP 5MG TABLET last: The duration of action for TANCODEP 5MG TABLET is clinically unknown.

What if you forget to take TANCODEP 5MG TABLET

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

•Keep the tablets in their original packaging to protect them from direct moisture, heat, and light. Do not store this medicine in the bathroom or in freezing conditions.

Drug Warnings

  • Use Caution During Activities: Avoid driving, operating machinery, or performing tasks requiring full mental alertness until you know how TANCODEP 5MG TABLET affects you, as it may cause drowsiness, dizziness, or impaired coordination.
  • Do Not Stop Suddenly: Abrupt discontinuation may cause withdrawal symptoms or worsen your condition. Your doctor will guide you on gradually reducing the dose when treatment needs to be stopped.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or other healthcare professional that you are taking TANCODEP 5MG TABLET before undergoing any medical or dental procedure or test.
  • Monitor Your Blood Pressure and Heart Rate: Regular monitoring may be advised, particularly during the first few weeks of treatment or after dose adjustments.
  • Attend Recommended Heart Checks: The imipramine component can affect the heart’s electrical activity in some people. Your doctor may recommend an ECG, a simple test that checks the heart’s rhythm, particularly if you have heart problems or other risk factors. 

Drug-Drug Interactions

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Certain medicines may interact with TANCODEP 5MG TABLET and alter its effects or increase the risk of serious side effects. Important interactions include:

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this if you are using or have recently used an MAOI within the last 14 days, as this combination can cause dangerously high blood pressure and body temperature.
  • Other Sedatives or Sleeping Pills: Taking this medicine with other drugs that slow down the brain, such as sleeping pills, strong pain relievers, or muscle relaxants, can cause extreme drowsiness and shallow breathing.
  • Blood Pressure Medications: TANCODEP 5MG TABLET may alter how certain blood pressure medicines work, potentially causing your blood pressure to drop too low when you stand up.
  • Certain Antidepressants: Some antidepressants, including certain SSRIs, may slow the breakdown of imipramine and increase its levels in the body. This may raise the risk of side effects, so your doctor may adjust the dose or monitor you more closely. 

Drug-Drug Interactions

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How does the drug interact with Tancodep 5mg Tablet:
Coadministration of Linezolid with Diazepam and Imipramine can increase the risk of side effects.

How to manage the interaction:
Taking Linezolid with Diazepam and Imipramine is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience fever, excessive sweating, muscle spasms, stomach cramps, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tancodep 5mg Tablet:
Taking Dronedarone with Tancodep 5mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone with Tancodep 5mg Tablet is generally avoided as it can result in an interaction, it can be taken only when a doctor has advised it. If you experience sudden dizziness, lightheadedness, shortness of breath, chest pain, or palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tancodep 5mg Tablet:
Coadministration of Isocarboxazid with Imipramine and Diazepam can increase the risk of side effects.

How to manage the interaction:
Taking Isocarboxazid with Imipramine and Diazepam can result in an interaction, it can be taken if your doctor has advised it. However, if you experience excessive sweating, muscle spasms, stomach cramps, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tancodep 5mg Tablet:
Taking Efavirenz with Tancodep 5mg Tablet can increase the risk of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz with Tancodep 5mg Tablet can result in an interaction, it can be taken if your doctor has advised it. If you experience sudden dizziness, fainting, shortness of breath, chest pain or tightness, or palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tancodep 5mg Tablet:
Co-administration of Dextromethorphan and Tancodep 5mg Tablet might rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction of Dextromethorphan and Tancodep 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, palpitations, fever, excessive sweating, muscle spasms or stiffness, stomach cramps, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Tancodep 5mg Tablet:
Taking Cisapride with Tancodep 5mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Cisapride with Tancodep 5mg Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain or tightness, or palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tancodep 5mg Tablet:
Coadministration of Ergotamine with Tancodep 5mg Tablet can increase serotonin hormone levels in the body, rarely affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Ergotamine with Tancodep 5mg Tablet can result in an interaction, it can be taken if your doctor has advised it. If you experience confusion, palpitations, fever, excessive sweating, muscle spasms or stiffness, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tancodep 5mg Tablet:
Coadministration of Imipramine and Diazepam with Naratriptan can increase the risk of side effects.

How to manage the interaction:
Taking Imipramine and Diazepam with Naratriptan can result in an interaction, it can be taken if your doctor has advised it. However, if you experience palpitations, fever, excessive sweating, shivering or shaking, muscle spasms, stomach cramps, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tancodep 5mg Tablet:
Taking Dofetilide with Tancodep 5mg Tablet can increase the risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dofetilide with Tancodep 5mg Tablet can result in an interaction, it can be taken if your doctor has advised it. If you experience sudden dizziness, shortness of breath, chest pain, or palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tancodep 5mg Tablet:
Taking Crizotinib with Tancodep 5mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Crizotinib with Tancodep 5mg Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain or tightness, palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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Certain foods and drinks may interact with TANCODEP 5MG TABLET and increase the risk of unwanted effects during treatment. Important interactions include:

  • Grapefruit and Grapefruit Juice: Grapefruit may slow the breakdown of the diazepam component, potentially increasing drowsiness, dizziness, or other side effects.
  • Alcohol: Dramatically increases brain-slowing effects, leading to severe drowsiness, confusion, and breathing difficulties.
DIAZEPAM-5MG+IMIPRAMINE-25MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DIAZEPAM-5MG+IMIPRAMINE-25MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine along with Tancodep 5mg Tablet may increase the risk of undesired side effects. Limit or avoid caffeine intake while taking Tancodep 5mg Tablet.

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

TANCODEP 5MG TABLET is used in the treatment of depression.
TANCODEP 5MG TABLET contains Imipramine and Diazepam. Imipramine is a tricyclic antidepressant. It works by increasing serotonin and noradrenalin levels, chemicals present in the brain responsible for energy, mood, and behavior. Diazepam is a benzodiazepine. It increases the levels of chemicals in the brain that produce a calming effect. Together, TANCODEP 5MG TABLET can effectively reduce the symptoms of depression.
TANCODEP 5MG TABLET may cause side-effects such as drowsiness, fatigue (extreme tiredness), confusion, loss of coordination of body movements (ataxia), dryness in the mouth, constipation, difficulty in urination, difficulty passing urine, low blood pressure, decrease in sexual function, dilation of the pupil of the eye, vision problems, loss of appetite, and increased heart rate. These side-effects usually don’t require medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.
TANCODEP 5MG TABLET can be addictive or habit-forming if taken for prolonged periods. So, it is advised to take TANCODEP 5MG TABLET only for a duration as intended by the doctor.
It is not advised to take other antidepressants, especially monoamine oxidase inhibitors (MAOI) such as phenelzine and moclobemide, while using TANCODEP 5MG TABLET. It may lead to unwanted effects. The doctor may advise you to wait for at least 14 days after discontinuing MAOI if you have been prescribed TANCODEP 5MG TABLET.
TANCODEP 5MG TABLET may affect blood sugar levels. So, it is necessary to inform your doctor that you have diabetes before taking this medicine.
TANCODEP 5MG TABLET may alter blood count, impair liver function, and cause problems with teeth. Therefore, you should regularly monitor blood cell levels, liver function tests and undergo dental check-ups while taking this medicine.
No, you should not stop taking TANCODEP 5MG TABLET suddenly. Stopping this medicine abruptly can cause withdrawal symptoms like headache, nausea, and rebound anxiety. Your doctor will help you by gradually decreasing dose when it is time to stop. Talk to your doctor before making any changes.
No, you must avoid alcohol while taking this medicine. Alcohol can dangerously increase drowsiness, cause severe coordination problems, and slow down your breathing. Talk to your doctor if you have concerns about avoiding alcohol.
Drowsiness is a common side effect, especially when starting the medicine. Avoid driving or operating machinery while feeling sleepy. Your doctor may suggest taking your dose closer to bedtime to help manage this. Talk to your doctor if the sleepiness persists or interferes with your daily routine.
Taking TANCODEP 5MG TABLET during pregnancy is generally not recommended as it may affect the developing baby. If you are pregnant, planning to become pregnant, or suspect you might be, talk to your doctor immediately to discuss the risks and alternative options.
Yes, dry mouth is a well-known side effect of this medicine. You can manage it by taking frequent sips of water, chewing sugar-free gum, or sucking on sugar-free hard candies. If dry mouth becomes severe or painful, talk to your doctor or pharmacist for advice.
You should not drive or perform any tasks requiring high alertness when you first start taking TANCODEP 5MG TABLET, as it can cause significant drowsiness, blurred vision, and slow reflexes. Only drive once you are certain the medicine does not impair your ability to do so safely. Talk to your doctor if you are unsure.

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Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TAN0004
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