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Tenfoclear 300 Tablet is used to treat HIV and chronic hepatitis B infection. It contains Tenofovir disoproxil fumarate which works by preventing the development of the virus in the human body. In some cases, this medicine may cause side effects such as diarrhoea, rash, nausea, pain, weakness, and stomach pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tenfoclear 300 Tablet

Tenfoclear 300 Tablet is a prescription antiviral medicine used to treat chronic hepatitis B and human immunodeficiency virus type 1 (HIV-1) infection in adults and certain children. It works by slowing the growth of the virus, helping protect the immune system, reduce liver damage, and lower the amount of virus in the body. Although it does not cure HIV or hepatitis B, it plays an important role in their long-term management.

For Tenfoclear 300 Tablet to work effectively, it must be taken exactly as prescribed, usually once daily at the same time each day. Missing doses can make the treatment less effective and increase the risk of the virus becoming resistant to Tenfoclear 300 Tablet . You can take Tenfoclear 300 Tablet with or without food, although taking it with food may help reduce stomach discomfort. Eating a balanced diet, staying well hydrated, avoiding alcohol, and following your doctor's advice can also help support your overall health during treatment.

While taking Tenfoclear 300 Tablet , some people may experience mild side effects such as nausea, diarrhea, headache, or tiredness. These side effects are usually manageable, but seek medical attention immediately if you develop severe muscle pain, unusual weakness, difficulty breathing, persistent vomiting, yellowing of the skin or eyes, or signs of kidney problems such as reduced urination or swelling of the legs.

Before starting Tenfoclear 300 Tablet , tell your doctor if you have kidney disease, liver disease, osteoporosis or other bone problems, or if you have both HIV and hepatitis B infection. Do not stop taking Tenfoclear 300 Tablet without your doctor's advice, especially if you have hepatitis B, as this may cause a serious worsening of your liver disease. Do not take Tenfoclear 300 Tablet if you are allergic to Tenfoclear 300 Tablet or any of its ingredients.

Tenfoclear 300 Tablet can interact with medicines that may affect kidney function, including certain pain relievers, antivirals, and some antibiotics, so always tell your doctor about all prescription medicines, over-the-counter medicines, and herbal supplements you are taking. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, discuss the benefits and risks of treatment with your healthcare provider before starting Tenfoclear 300 Tablet .

Uses of Tenfoclear 300 Tablet

Tenfoclear 300 Tablet is used in the treatment of HIV (Human Immunodeficiency Virus) infection and Chronic Hepatitis B. The detailed uses of Tenfoclear 300 Tablet are as follows:

  • HIV-1 Infection: Tenfoclear 300 Tablet helps manage HIV-1 by keeping the virus from multiplying, which protects your immune cells and helps lower the overall amount of virus in your body.
  • Chronic Hepatitis B: Tenfoclear 300 Tablet helps control the hepatitis B virus, preventing it from damaging your liver cells and reducing the risk of long-term liver scarring or liver failure.

Key Benefits

Tenfoclear 300 Tablet helps manage certain viral infections by reducing the amount of virus in the body and supporting long-term immune and liver health. When taken regularly as prescribed, it helps control the infection and improves overall health outcomes.
Benefits may include:

  •  Helps reduce viral activity and supports long-term control of HIV or chronic hepatitis B infection.
  • Supports immune system health by helping keep viral levels low.
  • Helps protect liver health in people with chronic hepatitis B.
  • Reduces the risk of disease progression and virus-related complications.
  • Provides convenient once-daily dosing to support consistent treatment.
  • Promotes long-term health and improved quality of life when taken as prescribed.
Side effects of Tenfoclear 300 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Directions for Use

  • Tenfoclear 300 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Tenfoclear 300 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Tenfoclear 300 Tablet Works

Tenfoclear 300 Tablet control viral infections by preventing the virus from making copies of itself. This reduces the amount of virus in the body, supports the immune system, and helps protect the liver from further damage.
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Alcohol

Caution

Avoid drinking alcohol. Consuming alcohol while using Tenfoclear 300 Tablet may worsen the condition.

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Pregnancy

Caution

Tenfoclear 300 Tablet is a category B medicine. It should be used with caution in pregnant women because it may cause side effects to the unborn baby.

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Breast Feeding

Unsafe

The active part of Tenfoclear 300 Tablet may pass with breast milk. Women who are HIV-positive must not breast-feed, because HIV infection can be passed on to the baby in breast milk.

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Driving

Caution

Tenfoclear 300 Tablet may cause dizziness. So, avoid driving or refrain from any activities that require you to alert mentally.

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Liver

Caution

Tenfoclear 300 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary. Patients with liver disease, who are treated with Tenfoclear 300 Tablet , have a higher risk of serious and possibly fatal liver complications.

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Kidney

Unsafe

Tenfoclear 300 Tablet should not be used in adolescents with kidney disease. In other people with severe kidney diseases, Tenfoclear 300 Tablet is given only if clinically needed.

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Children

Unsafe

Tenfoclear 300 Tablet should not be used in children below 12 years of age.

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Heart

Consult your doctor

It is unknown whether Tenfoclear 300 Tablet is safe for use in heart patients or not. Please consult your physician.

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Geriatrics

Caution

Tenfoclear 300 Tablet can be given in elderly patients with extreme caution, due to the cause of adverse effects like liver/kidney problems.

What if I have taken an overdose of Tenfoclear 300 Tablet

If you take more than your prescribed dose, seek emergency medical attention or call a poison control center immediately.

Diet & Lifestyle Advise

  • Drink plenty of water: Stay well-hydrated throughout the day to support your kidney function while your body processes this medication.
  • Avoid alcohol: Do not drink alcohol, as it can put extra stress on your liver and worsen existing liver conditions.
  • Support your bones: Ensure your diet includes adequate calcium and Vitamin D, or speak with your doctor about supplements, as Tenfoclear 300 Tablet can sometimes cause bone thinning.
  • Eat balanced meals: Maintain a nutrient-rich diet to help support your immune system and overall energy levels.
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How Soon It Starts Working

The time required for Tenfoclear 300 Tablet to start to work: Tenfoclear 300 Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Tenfoclear 300 Tablet last: The effect of Tenfoclear 300 Tablet lasts for 17 hours.

What if you forget to take Tenfoclear 300 Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose entirely and return to your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Tenfoclear 300 Tablet tablets at room temperature, strictly between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect Tenfoclear 300 Tablet before use: Do not take the tablets if they are discolored, cracked, damaged, or if the packaging shows signs of tampering.
  • Do not stop treatment abruptly: Do not stop taking Tenfoclear 300 Tablet suddenly, especially if you have hepatitis B, as this may cause a severe flare-up of your liver infection. Always consult your doctor before stopping treatment.
  • Attend regular monitoring appointments: Keep all scheduled blood and urine test appointments so your doctor can monitor your kidney function, liver function, and overall response to treatment.
  • Keep an updated medication list: Maintain a current list of all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take, and share it with your doctor, dentist, or any other healthcare professional involved in your care.

Drug-Drug Interactions

verifiedApollotooltip
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen, diclofenac): Taking these medicines alongside Tenfoclear 300 Tablet may increase the risk of kidney damage.
  • Other antiviral medicines (for HIV or hepatitis C): Certain antiviral medicines may increase the amount of Tenfoclear 300 Tablet in the body, raising the risk of side effects.
  • Anti-viral medicine (e.g., Adefovir dipivoxil): Do not take Tenfoclear 300 Tablet alongside Tenfoclear 300 Tablet , as using both together may increase the risk of serious side effects.
Critical
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Didanosine with Tenfoclear 300 Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tenfoclear 300 Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Tenfoclear 300 Tablet:
Combining Tenfoclear 300 Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenfoclear 300 Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
When Tenfoclear 300 Tablet is taken with Adefovir dipivoxil, the amount of Tenfoclear 300 Tablet in the blood can go up.

How to manage the interaction:
Combining Tenfoclear 300 Tablet with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Deferoxamine with Tenfoclear 300 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Deferoxamine and Tenfoclear 300 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Olsalazine and Tenfoclear 300 Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Olsalazine and Tenfoclear 300 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like vomiting, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilPhenylbutazone
Severe
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Phenylbutazone and Tenfoclear 300 Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Phenylbutazone and Tenfoclear 300 Tablet can lead to an interaction, it can be taken when your doctor advises. However, if you experience any symptoms like vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Tenfoclear 300 Tablet with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Taking Tenfoclear 300 Tablet with Polymyxin B together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Sulfasalazine and Tenfoclear 300 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Sulfasalazine and Tenfoclear 300 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Mefenamic acid with Tenfoclear 300 Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Tenfoclear 300 Tablet may result in an interaction, but it can be taken together if a doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Tenfoclear 300 Tablet:
Coadministration of Neomycin and Tenfoclear 300 Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Neomycin and Tenfoclear 300 Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Tenfoclear 300 Tablet when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Tenfoclear 300 Tablet is used to treat HIV and chronic hepatitis B infection.
In the case of HIV infection, Tenfoclear 300 Tablet may decrease the risk of spreading the virus to others, but the risks of infecting others still continue. Although, in the case of hepatitis B virus infection, Tenfoclear 300 Tablet has not proven to decrease the risk of transferring the virus to others. Thereby, the patients of both HIV infection and hepatitis B virus (HBV) infection should not share needles and should practice safe sex.
Tenfoclear 300 Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Duration of treatment will depend on the seriousness of hepatitis B virus infection. You will require to take regular blood tests to keep a check on the viral load. Your doctor will then decide the duration of the Tenfoclear 300 Tablet appropriately. In a few cases, treatment is needed lifelong.
Tenfoclear 300 Tablet works by prevents the development of viruses in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.
The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-colored urine.
Tenfoclear 300 Tablet does not prevent the chance of transmission of new virus infection. Therefore, always take necessary precautions as per national guidelines for the prevention of transmission of new virus infection.
If you have Tuberculosis, HIV-1 virus infection or any other medical condition, you are recommended to inform your doctor before taking Tenfoclear 300 Tablet .
You should take Tenfoclear 300 Tablet in the dose and duration prescribed by your doctor. Take Tenfoclear 300 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.
If you vomit within 1 hour of taking Tenfoclear 300 Tablet , take another one. However, you need not take another tablet if you vomit after more than an hour of taking Tenfoclear 300 Tablet . If you experience vomiting whenever you take Tenfoclear 300 Tablet or if the vomiting persists for a longer duration, consult your doctor.
If you forget to take Tenfoclear 300 Tablet within 12 hours of your usual dosing time, you should take it with food as soon as possible and go back to the normal dosing schedule. If you miss a dose of Tenfoclear 300 Tablet by more than 12 hours and it is almost time for your next dose, you should skip the missed dose and simply resume the regular dosing schedule.
The side effects of Tenfoclear 300 Tablet include nausea, diarrhoea, rash, weakness, and stomach pain. If any of these side effects persist or worsen, please consult your doctor.
Unexplained muscle weakness, especially when accompanied by deep, rapid breathing or extreme tiredness, can be a sign of a serious condition called lactic acidosis. Stop taking Tenfoclear 300 Tablet and seek immediate emergency medical care if you experience these symptoms.
It is highly recommended to avoid or strictly limit alcohol while taking this medication. Alcohol increases stress on your liver, which can worsen liver damage, especially if you are being treated for hepatitis B. Talk to your doctor or pharmacist for personalized advice.
Yes, some people experience a decrease in bone mineral density while taking this medication. Your doctor may monitor your bone health or suggest calcium and vitamin D supplements. Talk to your doctor or pharmacist if you have concerns about your bone health.
You should avoid taking pain relievers known as NSAIDs (like ibuprofen or naproxen) regularly while taking Tenfoclear 300 Tablet , as they can increase the risk of kidney damage. Speak to your doctor or pharmacist to find a safer pain relief alternative.

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Country of origin

INDIA

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In
Other Info - TEN0281
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