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  1. Home
  2. Medicine

  3. Tenvir-L Tablet 30's

Prescription drug
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Tenvir-L Tablet 30's, Pack of 1 TABLET
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Composition :

LAMIVUDINE-300MG + TENOFOVIR DISOPROXIL FUMARATE-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tenvir-L Tablet

Tenvir-L Tablet belongs to a class of drugs called antiretrovirals used to treat HIV infection. Tenvir-L Tablet helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Tenvir-L Tablet is a combination of two drugs, namely: Lamivudine and Tenofovir disoproxil fumarate. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tenvir-L Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Tenvir-L Tablet helps in treating HIV infection.

Take Tenvir-L Tablet as prescribed by your doctor. You are advised to take Tenvir-L Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, nausea, vomiting, diarrhea, weakness, or rash. Most of these side effects of Tenvir-L Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tenvir-L Tablet or any other medicines, soya or peanut, please tell your doctor. If you are pregnant or planning for pregnancy, please consult a doctor before taking Tenvir-L Tablet . Avoid breastfeeding while taking Tenvir-L Tablet as it may pass into breast milk. Tenvir-L Tablet is not recommended for children below 18 years of age. You are recommended to avoid the consumption of alcohol with Tenvir-L Tablet as it may increase the risk of liver damage. Drive only if you are alert as Tenvir-L Tablet may cause dizziness.

Uses of Tenvir-L Tablet

Tenvir-L Tablet is used in the treatment of HIV infection. The detailed use of Tenvir-L Tablet is as follows:

  • HIV-1 Infection: Tenvir-L Tablet is used in combination with other antiretroviral agents to reduce viral load and increase CD4 cell count.

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Directions for Use

  • Tenvir-L Tablet can be taken with food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Tenvir-L Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

Tenvir-L Tablet is a combination of two drugs, namely: Lamivudine and Tenofovir disoproxil fumarate used to treat HIV infection. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tenvir-L Tablet interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Tenvir-L Tablet helps in treating HIV infection. Taking Tenvir-L Tablet along with practicing safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.

How Tenvir-L Tablet Works

Tenvir-L Tablet is a combination of two drugs, namely: Lamivudine and Tenofovir disoproxil fumarate. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Tenvir-L Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Tenvir-L Tablet helps in treating HIV infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Tenvir-L Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Tenvir-L Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Pancreatitis: A Step-by-Step Guide:
  • If you take medication and get severe stomach pain, feel nauseous, vomit, or have a fever, get emergency medical help right away. This could be a sign of pancreatitis, an inflammation of the pancreas.
  • Your doctor may alter your treatment plan, provide supportive therapy, or prescribe alternative medications to manage the reaction. They will also perform regular tests to monitor your progress and adjust your treatment as needed.
  • Follow your doctor's advice, including dietary recommendations and lifestyle changes, and avoid triggers like alcohol and fatty foods.
  • Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Tenvir-L Tablet

Take Tenvir-L Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Tenvir-L Tablet or any other medicines, soya or peanut, please tell your doctor. If you are pregnant or planning for pregnancy, please consult a doctor before taking Tenvir-L Tablet . Avoid breastfeeding while taking Tenvir-L Tablet as it may pass into breast milk. Tenvir-L Tablet is not recommended for children below 18 years of age. You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. If you experience stomach pain, vomiting or nausea while taking Tenvir-L Tablet , please consult a doctor immediately as these might be symptoms of a rare but severe side effect known as lactic acidosis (excess of lactic acid in the blood). You are recommended to avoid consumption of alcohol with Tenvir-L Tablet as it may increase the risk of liver damage. Drive only if you are alert as Tenvir-L Tablet may cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
Tenofovir disoproxilDidanosine
Critical
Tenofovir disoproxilStreptozocin
Critical

Drug-Drug Interactions

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Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Tenvir-L Tablet:
Coadministration of Didanosine with Tenvir-L Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tenvir-L Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Tenvir-L Tablet:
Combining Tenvir-L Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenvir-L Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Tenvir-L Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Tenvir-L Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
Tenofovir disoproxilRifampicin
Severe
How does the drug interact with Tenvir-L Tablet:
Rifampin may significantly lower the tenofovir levels in your blood, possibly decreasing its effectiveness in treating your condition.

How to manage the interaction:
Although taking Rifampicin together with Tenvir-L Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilIbuprofen
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Tenvir-L Tablet and Ibuprofen can increase the risk of developing kidney problems.

How to manage the interaction:
Co-administration of Tenvir-L Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, weakness, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilKetorolac
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Ketorolac with Tenvir-L Tablet may increase the risk of developing kidney problems.

How to manage the interaction:
Although taking Ketorolac and Tenvir-L Tablet together can possibly result in an interaction, it can be taken when your doctor has prescribed it. However, if you experience symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, shortness of breath, fatigue, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilPenicillamine
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Tenvir-L Tablet with Penicillamine can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Tenvir-L Tablet with Penicillamine can possibly result in an interaction, it can be taken when your doctor has advised it. However, if you experience vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilAciclovir
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Aciclovir with Tenvir-L Tablet may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Aciclovir with Tenvir-L Tablet can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilFlurbiprofen
Severe
How does the drug interact with Tenvir-L Tablet:
Co-administration of Flurbiprofen with Tenvir-L Tablet can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Flurbiprofen with Tenvir-L Tablet can possibly result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting your doctor.
Tenofovir disoproxilOxcarbazepine
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Oxcarbazepine with Tenvir-L Tablet can reduce the levels of Tenvir-L Tablet in the blood, which can lead to low treatment outcomes.

How to manage the interaction:
Although taking Oxcarbazepine with Tenvir-L Tablet can lead to interaction, it can be taken when a doctor advices. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections, or drug equipment.
  • Get tested for other sexually transmitted infections such as gonorrhea or syphilis as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Tenvir-L Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid alcohol consumption with Tenvir-L Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Tenvir-L Tablet is given to pregnant women if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Tenvir-L Tablet as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Tenvir-L Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Tenvir-L Tablet .

bannner image

Liver

Caution

Take Tenvir-L Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Tenvir-L Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Tenvir-L Tablet is not recommended for children below 18 years of age.

FAQs

Tenvir-L Tablet is used to treat HIV infection. It helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome).

Tenvir-L Tablet contains Lamivudine and Tenofovir disoproxil fumarate. Tenvir-L Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Tenvir-L Tablet helps in treating HIV infection.

Tenvir-L Tablet may cause bone problems such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. However, if you experience joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.

HIV infection may still be transmitted to other persons while using Tenvir-L Tablet . Tenvir-L Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to be taken to avoid transmission of HIV while taking Tenvir-L Tablet .

Tenvir-L Tablet does not cure HIV infection. Tenvir-L Tablet reduces the amount of HIV virus in the body and improves the functioning of the immune system.

Tenvir-L Tablet should be used with caution in patients with existing infections as it may worsen the infection. However, please consult a doctor if you notice any signs of infection or inflammation.

Tenvir-L Tablet may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver disease. However, if you experience stomach pain, vomiting or nausea while taking Tenvir-L Tablet , please consult a doctor immediately.

Tenvir-L Tablet is safe if used in the dose and duration as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if you experience any of the side effects.

Always take Tenvir-L Tablet exactly as advised by your doctor. Do not crush or break it. You can take Tenvir-L Tablet with food or between meals.

If you forget to take a dose of Tenvir-L Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

The common side effects of Tenvir-L Tablet are dizziness, nausea, vomiting, diarrhoea, weakness and rash. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - TEN0200

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 8, 2025 | 8:42 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.10500.pdf
  2. https://www.drugs.com/mtm/lamivudine-and-tenofovir.html

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