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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Tixituss Syrup is used to treat a dry cough. This medicine works by preventing nerve signals from the brain's cough centre from reaching the muscles that cause coughing, thus reducing cough. You may experience common side effects, such as headache, dizziness, numbness, drowsiness, or nausea.

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About Tixituss Syrup

Tixituss Syrup is used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. A dry cough is tickly and doesn't produce any viscous or thick mucus, while a chesty cough (wet cough) means mucus or sputum is created to help clear the airways.

Tixituss Syrup is a combination of three drugs: Chlorpheniramine, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine. Phenylephrine helps in shrinking the blood vessels located in the nasal passage. Dextromethorphan works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce a cough.

Some people may experience dry mouth, throat, or nose, as well as drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Tixituss Syrup . Avoid using Tixituss Syrup if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, an enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of the amino acid phenylalanine in the body), a cough with mucus or a cough caused by asthma or smoking, inform your doctor before taking it.

Uses of Tixituss Syrup

Tixituss Syrup is used in the treatment of dry cough. The detailed uses of Tixituss Syrup are as follows:

  • Treatment of dry cough: Tixituss Syrup suppresses dry cough by reducing the urge to cough.
  • Relieves cold symptoms: Tixituss Syrup relieves sneezing and a runny nose caused by allergies or a cold.
  • Treats throat irritation: Tixituss Syrup reduces throat irritation for more comfort.

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Directions for Use

  • Tixituss Syrup can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, break or chew it.

Key Benefits

  • Tixituss Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. 
  • Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. 
  • Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
  • Thus, Tixituss Syrup helps to relieve overall cough, cold and allergic symptoms.

How Tixituss Syrup Works

Tixituss Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tixituss Syrup 100 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Tixituss Syrup

Take this medicine only as prescribed. An overdose of Tixituss Syrup may cause agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, and seizures. Seek immediate medical attention if you experience any of these symptoms.

Drug Warnings

  • If you are allergic to Tixituss Syrup or any other medicines, please tell your doctor.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
  • Tixituss Syrup is not recommended for children below 12 years of age.
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
  • Avoid taking Tixituss Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
  • If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Tixituss Syrup .

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Phenelzine and Tixituss Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Tixituss Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Tixituss Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Tixituss Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Pargyline and Tixituss Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Tixituss Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Tixituss Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Tixituss Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tixituss Syrup 100 ml:
Taking Tranylcypromine with Tixituss Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Tixituss Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Isocarboxazid with Tixituss Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Tixituss Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tixituss Syrup 100 ml:
Taking Rasagiline with Tixituss Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tixituss Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tixituss Syrup 100 ml:
Co-administration of Selegiline with Tixituss Syrup 100 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Tixituss Syrup 100 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tixituss Syrup 100 ml:
Taking Furazolidone with Tixituss Syrup 100 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Tixituss Syrup 100 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Tixituss Syrup 100 ml only after 14 days of stopping Furazolidone.
How does the drug interact with Tixituss Syrup 100 ml:
Taking Tixituss Syrup 100 ml with Propofol may lead to increased levels of Tixituss Syrup 100 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Tixituss Syrup 100 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as they may increase mucus production. Also, avoid processed or refined foods.
  • Drink plenty of fluids to avoid a dry throat while you have a cough. This will also help loosen mucus.
  • Avoid citrus fruits, as they may worsen the cough. Eat fruits rich in water, such as pears, watermelon, peaches, and pineapples.

Habit Forming

No

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]
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Alcohol

Safe if prescribed

Avoid consumption of alcohol with Tixituss Syrup as it may increase drowsiness.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before taking Tixituss Syrup . Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Due to the potential harm to nursing infants, breastfeeding should be discontinued while on treatment with this medicine. Please consult your doctor for more information.

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Driving

Safe if prescribed

Tixituss Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking this medicine.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before taking Tixituss Syrup . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Tixituss Syrup . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Tixituss Syrup is not recommended for children below 12 years of age. However, please consult a doctor for medical advice.

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Heart

Tixituss Syrup should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Tixituss Syrup .

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Geriatrics

Consult your doctor

Tixituss Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Tixituss Syrup .

FAQs

Tixituss Syrup is used to treat dry cough.

Tixituss Syrup contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce a cough.

Consult your doctor before taking Tixituss Syrup if you need to undergo surgery, as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Tixituss Syrup 72 hours prior to the surgery.

It is not recommended to take Tixituss Syrup along with any antidepressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side effects or drug interactions. Also, Tixituss Syrup should be taken at least 14 days after your last dose of antidepressants.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your schedule. Do not take extra medicine to make up for the missed dose.

Tixituss Syrup may rarely worsen the symptoms of glaucoma. Therefore, Tixituss Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.

Tixituss Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Tixituss Syrup . Avoid consumption of alcohol as it may increase drowsiness.

No, Tixituss Syrup does not contain steroids. It contains an antihistamine (chlorpheniramine maleate), a decongestant (phenylephrine hydrochloride), and a cough suppressant (dextromethorphan hydrobromide).

Yes, Tixituss Syrup may cause sleepiness or drowsiness. Therefore, drive or operate machinery only if you are alert.

No, Tixituss Syrup will not be more effective if taken in a dose greater than the recommended amount. Avoid exceeding the recommended dose as it might cause an overdose, leading to unpleasant side effects.

Consult the doctor if you are breastfeeding; your doctor will decide if Tixituss Syrup can be taken by breastfeeding mothers or not.

Store Tixituss Syrup at room temperature, in a dry place. Keep it out of sight and reach of children.

Tixituss Syrup is not recommended for children below 12 years of age. However, please consult a doctor for medical advice.

After taking Tixituss Syrup , it is advised to wait for a while before drinking water.

Tixituss Syrup should be taken as advised by the doctor. Talk to your doctor if you have any concerns.

No, Tixituss Syrup is not a steroid. It is a cough suppressant used to treat a dry cough.

No, Tixituss Syrup is not an antibiotic. It is a combination medicine used to treat cough.

Tixituss Syrup may cause side effects like dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

604, Building A1 Mukta Kalyan Shil Road Dombivili (E) Thane (W) Maharashtra-421204
Other Info - TIX0027

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