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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tolol XR 12.5 Tablet is used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it may also help in relieving symptoms of migraine-related headache and tremors (fits). It contains Metoprolol, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. In some cases, it may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

METOPROLOL-12.5MG

Manufacturer/Marketer :

Unichem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tolol XR 12.5 Tablet

Tolol XR 12.5 Tablet belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Hypertension or high blood pressure is a chronic condition in which the blood exerts an increased pressure against the arteries that may lead to various types of heart diseases. Besides this, Tolol XR 12.5 Tablet may also help in relieving symptoms of migraine-related headache and tremors (fits). 

Tolol XR 12.5 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

Based on your medical condition, your doctor will decide the dose and duration. In some cases, Tolol XR 12.5 Tablet may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have low blood pressure, asthma, overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Tolol XR 12.5 Tablet if you are pregnant or breastfeeding. Tolol XR 12.5 Tablet is not recommended for use in children. Tolol XR 12.5 Tablet may cause dizziness, so drive with caution. Avoid alcohol consumption while taking Tolol XR 12.5 Tablet as it might increase the blood pressure-lowering effect of Tolol XR 12.5 Tablet . Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Tolol XR 12.5 Tablet

Treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

Directions for Use

Swallow Tolol XR 12.5 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tolol XR 12.5 Tablet belongs to a group of medicines called beta-blockers used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it also helps in relieving symptoms of migraine-related headaches and tremors (fits).  Tolol XR 12.5 Tablet  helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. 

How Tolol XR 12.5 Tablet Works

Tolol XR 12.5 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tolol XR 12.5 Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Tolol XR 12.5 Tablet

Do not take more than the prescribed dose of Tolol XR 12.5 Tablet as it may cause overdose. The symptoms of overdose include slow heart rate, difficulty breathing, trembling or dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Tolol XR 12.5 Tablet if you are allergic to Tolol XR 12.5 Tablet or any other beta-blockers. Avoid taking Tolol XR 12.5 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or prinzmetal angina. Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents. Consult your doctor before taking Tolol XR 12.5 Tablet if you are pregnant or breastfeeding. Tolol XR 12.5 Tablet is not recommended for children as safety and efficacy have not been established. Tolol XR 12.5 Tablet may cause dizziness, so drive with caution. Let your doctor know if you are taking other prescription/non-prescription medicines or herbal supplements.

Drug-Drug Interactions

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MetoprololElvitegravir
Severe
MetoprololVerapamil
Severe

Drug-Drug Interactions

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MetoprololElvitegravir
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Taking elvitegravir may increase the metabolism of Tolol XR 12.5 Tablet.

How to manage the interaction:
Although there may be an interaction, Tolol XR 12.5 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololVerapamil
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Coadministration of Tolol XR 12.5 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Tolol XR 12.5 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololAminophylline
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Coadministration of Aminophylline with Tolol XR 12.5 Tablet together can make Tolol XR 12.5 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Tolol XR 12.5 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololArtemether
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Both Tolol XR 12.5 Tablet and Artemether may increase the blood levels and effects of Tolol XR 12.5 Tablet activity.

How to manage the interaction:
Taking Tolol XR 12.5 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololDiltiazem
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Coadministration of Tolol XR 12.5 Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Tolol XR 12.5 Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAtazanavir
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Use of Tolol XR 12.5 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Tolol XR 12.5 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Combine use of Tolol XR 12.5 Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Tolol XR 12.5 Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololTizanidine
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Coadministration of Tolol XR 12.5 Tablet and Tizanidine may reduce the efficiency of Tolol XR 12.5 Tablet.

How to manage the interaction:
Taking Tolol XR 12.5 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololCeritinib
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Taking ceritinib together with Tolol XR 12.5 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Tolol XR 12.5 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Tolol XR 12.5 Tablet:
Coadministration of Acebutolol with Tolol XR 12.5 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Tolol XR 12.5 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular physical activity or exercise.

  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet.

  • Quitting smoking is the best strategy to lower the risk of heart disease. 

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Tolol XR 12.5 Tablet Substitute

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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Tolol XR 12.5 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Tolol XR 12.5 Tablet .

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Pregnancy

Caution

Tolol XR 12.5 Tablet is not recommended for use during pregnancy. If you are pregnant or planning for pregnancy, consult your doctor.

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Breast Feeding

Caution

Tolol XR 12.5 Tablet may pass into breastmilk. Consult a doctor before taking Tolol XR 12.5 Tablet if you are breastfeeding.

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Driving

Caution

Tolol XR 12.5 Tablet may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Tolol XR 12.5 Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Tolol XR 12.5 Tablet if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Tolol XR 12.5 Tablet is not recommended in children as the safety and efficacy have not been established.

FAQs

Tolol XR 12.5 Tablet is indicated in the treatment of high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

Tolol XR 12.5 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.

Do not stop taking Tolol XR 12.5 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Tolol XR 12.5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Tolol XR 12.5 Tablet .

Consult your doctor before taking Tolol XR 12.5 Tablet if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).

Consult your doctor before taking Tolol XR 12.5 Tablet with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking Tolol XR 12.5 Tablet is advised.

Your doctor may probably ask you to stop taking Tolol XR 12.5 Tablet 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Tolol XR 12.5 Tablet .

Taking Tolol XR 12.5 Tablet along with multivitamin/multimineral supplements may decrease the effect of Tolol XR 12.5 Tablet . Therefore, maintain a gap of at least 2 hours between both. However, you are advised to take Tolol XR 12.5 Tablet with other medicines only after consulting your doctor.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Tolol XR 12.5 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Yes, Tolol XR 12.5 Tablet contains metoprolol which belongs to a group of medicines called beta-blockers.

No, Tolol XR 12.5 Tablet is not a blood thinner. It is an antihypertensive medicine.

Tolol XR 12.5 Tablet starts working within 2 hours. However, it can take up to a week to show its full effect.

No, it is not dangerous to take Tolol XR 12.5 Tablet . It is safe to take Tolol XR 12.5 Tablet if prescribed by the doctor.

Tolol XR 12.5 Tablet may cause sleepiness. Drive or operate machinery only if you are alert. Consult the doctor if you have sleep problems.

Alcohol might increase the blood pressure-lowering effect of Tolol XR 12.5 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Tolol XR 12.5 Tablet .

Tolol XR 12.5 Tablet may cause side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - TOL0011

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