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compositionComposition:LAMOTRIGINE-50MG
prescription
Prescription Medicine
info
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Trigil-50 mg Tablet 10's is used to treat epilepsy/seizures/fits. Additionally, it also treats bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and firing of the nerve impulses that cause fits. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, dry mouth, dizziness, fatigue, abdominal pain, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LAMOTRIGINE-50MG

Manufacturer/Marketer :

Xender Biopharma & Research Llp

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Trigil-50 mg Tablet 10's

Trigil-50 mg Tablet 10's is a prescription oral tablet used to help control certain types of seizures in people with epilepsy and to delay or prevent mood episodes in adults with Bipolar I disorder. By stabilising abnormal electrical activity in the brain, this medicine helps reduce seizures and supports long-term mood stability.

To get the best results, it is important to take Trigil-50 mg Tablet 10's exactly as prescribed at the same time every day. You can take the tablet with or without food. Maintaining a regular sleep schedule, avoiding missed doses, and managing stress can help improve your treatment outcomes.

While taking Trigil-50 mg Tablet 10's, you may experience mild side effects such as dizziness, sleepiness, headache, or nausea, especially when starting treatment or after a dose increase. However, if you develop a skin rash, blistering, fever, swollen lymph nodes, or signs of a severe allergic reaction, stop taking the medicine and seek immediate medical attention, as these reactions can be serious.

Before starting Trigil-50 mg Tablet 10's, tell your doctor if you have kidney or liver disease, heart problems, depression, suicidal thoughts, or have previously experienced an allergic reaction to Trigil-50 mg Tablet 10's or similar medicines. Your doctor may adjust your dose or monitor you more closely during treatment.

This medicine can interact with several prescription medicines, over-the-counter products, hormonal contraceptives, and alcohol. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your healthcare provider to determine whether this medicine is suitable for you. 

Uses of Trigil-50 mg Tablet 10's

Your doctor may prescribe this medicine to treat several conditions, including:

  • Epilepsy: Trigil-50 mg Tablet 10's helps control partial-onset seizures, primary generalised tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome by stabilising abnormal electrical activity in the brain.
  • Bipolar I Disorder: This medication is used as a maintenance treatment to delay or prevent mood episodes, particularly depressive episodes, in adults with Bipolar I disorder.
     

Key Benefits

Trigil-50 mg Tablet 10's helps control seizures and maintain mood stability by reducing abnormal electrical activity in the brain. Regular use can improve day-to-day functioning, reduce the risk of recurring symptoms, and enhance overall quality of life. Key benefits include:

  • Helps Control Seizures: This medication reduces the frequency and severity of certain types of seizures, helping improve safety and confidence during daily activities.
  • Supports Long-Term Mood Stability: For adults with Bipolar I disorder, it helps delay or prevent mood episodes, particularly depression, supporting emotional stability over time.
  • Improves Daily Functioning: By helping manage seizures or mood fluctuations, this medication allows many people to maintain a more consistent routine and participate more comfortably in work, school, and social activities.
     
Side effects of Trigil-50 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Wear an eye patch or opaque contact lens or lens applied to glasses to block the vision of one eye to minimize double vision.
  • Use prisms (lenses applied to glasses) to correct double vision due to small misalignments.
  • Try doing some eye exercises such as moving the target towards nose slowly or focussing on a detailed target like thin stick or small text in a magazine.
  • If you feel eye pain, develop bulging eyes, have weakness, headache or double vision, consult a doctor immediately.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Directions for Use

  • Take Trigil-50 mg Tablet 10's with food or as directed by your doctor.
  • Always follow your doctor’s advice regarding the prescribed dosage and duration of treatment.
  • Swallow Trigil-50 mg Tablet 10's whole with a glass of water.
  • Do not crush, chew, or break the tablet.

How Trigil-50 mg Tablet 10's Works

Trigil-50 mg Tablet 10's contains lamotrigine, which works by stabilising abnormal electrical activity in the brain. It blocks voltage-sensitive sodium channels on nerve cells, reducing the excessive electrical signals that can trigger seizures. It also decreases the release of excitatory neurotransmitters, particularly glutamate and aspartate, which helps prevent excessive stimulation of brain cells. Although its exact mechanism in Bipolar I disorder is not fully understood, these actions are believed to contribute to improved mood stability and reduced recurrence of mood episodes.
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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Trigil-50 mg Tablet 10's. Alcohol intake, along with Trigil-50 mg Tablet 10's, may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Trigil-50 mg Tablet 10's is a pregnancy category C drug. Animal studies showed that Trigil-50 mg Tablet 10's affects the fetus in pregnancy, but there is limited data in humans. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborns. Please consult your doctor before taking Trigil-50 mg Tablet 10's if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Trigil-50 mg Tablet 10's is excreted into the breast milk. Please consult your doctor before taking Trigil-50 mg Tablet 10's if you are a breastfeeding mother.

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Driving

Unsafe

Trigil-50 mg Tablet 10's may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Trigil-50 mg Tablet 10's can be given to children if prescribed by the doctor. The doctor will adjust the dose.

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Heart

Caution

Trigil-50 mg Tablet 10's can be used in heart patients due to the increased risk of side effects. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Trigil-50 mg Tablet 10's should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Trigil-50 mg Tablet 10's

If you take more than the prescribed dose, seek immediate medical attention or contact your nearest poison control centre. Symptoms of overdose may include severe dizziness, drowsiness, poor coordination, rapid eye movements, seizures, or loss of consciousness.

Diet & Lifestyle Advise

 

  • Maintain a regular sleep schedule: Aim for 7–9 hours of quality sleep each night, as sleep deprivation can increase the risk of seizures and trigger mood episodes.
  • Limit or avoid alcohol: Alcohol can worsen dizziness and drowsiness, interfere with your treatment, and may increase the risk of seizures or mood instability.
  • Manage stress effectively: Practise relaxation techniques such as meditation, deep breathing exercises, yoga, or other activities that help reduce stress.
  • Track your treatment: Keep a diary of your medication schedule, seizure activity, mood changes, and any side effects to help your doctor monitor your progress and adjust treatment if needed.
     
health query

Have a query?

How Soon It Starts Working

  • The time required for Trigil-50 mg Tablet 10's to start to work: The effect of Trigil-50 mg Tablet 10's is observed within 1 to 3 hours of administration.
  • The time for which the effects of Trigil-50 mg Tablet 10's last: Trigil-50 mg Tablet 10's effect lasts for 24 hours.

What if you forget to take Trigil-50 mg Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed several consecutive doses, contact your doctor before restarting the medicine, as you may need to begin with a lower dose again.

Storage

• Store Trigil-50 mg Tablet 10's at room temperature, ideally between 20°C and 25°C.

Drug Warnings

  • Watch for skin rash: Seek immediate medical attention if you develop a rash, blistering, or peeling skin, especially during the first 2–8 weeks of treatment.
  • Take it consistently: Do not skip doses, as missed doses may increase the risk of seizures or reduce treatment effectiveness.
  • Check your medicine: If your tablets look different after a refill, confirm with your pharmacist before taking them.
  • Avoid driving initially: Until you know how this medicine affects you, avoid driving or operating machinery.
  • Inform healthcare providers: Tell your doctor, dentist, or surgeon that you are taking Trigil-50 mg Tablet 10's before any medical or dental procedure.
     

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor about all medicines you are taking before starting this medicine, as they may interact with Trigil-50 mg Tablet 10's and affect your treatment.

  • Hormonal contraceptives: Combined hormonal contraceptives may reduce Trigil-50 mg Tablet 10's levels, while Trigil-50 mg Tablet 10's may slightly reduce progestin levels in some contraceptives. Your doctor may adjust your treatment if needed.
  • Other antiepileptic medicines: Valproate significantly increases Trigil-50 mg Tablet 10's levels and the risk of serious skin reactions, whereas carbamazepine, phenytoin, phenobarbital, and primidone may reduce Trigil-50 mg Tablet 10's levels.
     
LamotrigineDofetilide
Critical
LamotrigineKetamine
Severe

Drug-Drug Interactions

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LamotrigineDofetilide
Critical
How does the drug interact with Trigil-50 mg Tablet:
Taking Dofetilide with Trigil-50 mg Tablet may significantly increase the blood levels of dofetilide. High blood levels of dofetilide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Trigil-50 mg Tablet with Dofetilide is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting and shortness of breath. Do not discontinue any medications without consulting a doctor.
LamotrigineKetamine
Severe
How does the drug interact with Trigil-50 mg Tablet:
Using Ketamine and Trigil-50 mg Tablet together can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Ketamine and Trigil-50 mg Tablet, you can take these medicines together if prescribed by your doctor. If you feel dizzy, sleepy, confused, have trouble focusing, or have trouble breathing, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
LamotrigineEsketamine
Severe
How does the drug interact with Trigil-50 mg Tablet:
Coadministration of Trigil-50 mg Tablet with Esketamine can increase the risk of serious side effects.

How to manage the interaction:
There may be a possibility of interaction between Trigil-50 mg Tablet and Esketamine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, loss of balance, or confusion, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
LamotrigineDivalproex
Severe
How does the drug interact with Trigil-50 mg Tablet:
Coadministration of Divalproex and Trigil-50 mg Tablet can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divalproex and Trigil-50 mg Tablet, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
LamotrigineBuprenorphine
Severe
How does the drug interact with Trigil-50 mg Tablet:
When buprenorphine is used with Trigil-50 mg Tablet, it may possibly lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Trigil-50 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
LamotrigineSodium oxybate
Severe
How does the drug interact with Trigil-50 mg Tablet:
Taking Trigil-50 mg Tablet with sodium oxybate can increase the risk and severity of side effects.

How to manage the interaction:
Taking Trigil-50 mg Tablet with Sodium oxybate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol may increase dizziness, drowsiness, and impaired coordination
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Trigil-50 mg Tablet 10's is used in the treatment of Epilepsy (fits) and Bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Trigil-50 mg Tablet 10's decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.
Do not discontinue Trigil-50 mg Tablet 10's without consulting your doctor. To treat your condition effectively, continue taking Trigil-50 mg Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Trigil-50 mg Tablet 10's. Your doctor will reduce the dose gradually to avoid worsening seizures.
Lamotrigine is generally considered weight-neutral and is unlikely to cause significant weight gain or weight loss in most people. However, individual responses may vary. If you notice unexpected changes in your weight, consult your doctor. Maintaining a healthy diet and regular exercise is recommended.
Dry mouth could be a side-effect of Trigil-50 mg Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Trigil-50 mg Tablet 10's helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.
Trigil-50 mg Tablet 10's contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.
The side effects of Trigil-50 mg Tablet 10's include sleepiness, dizziness, tremor, back pain, headache, nausea, vomiting, diarrhoea, blurred or double vision, tiredness, fever, dry mouth, sore throat, stuffy nose, stomach pain and infections, including seasonal flu. However, if these side effects persist or worsen, please consult your doctor.
Epilepsy also called as seizure disorder is a brain-related disorder affecting people of all ages characterized by repeated seizures that are brief episodes of involuntary movement that may involve a part of the body or full body. It is caused due to abnormal electrical activity in the brain and sometimes followed by loss of consciousness and control of bladder or bowel function.
Bipolar disorder also called as manic depression is a mental illness that causes unusual shifts in a person's mood, energy, concentration, and activity levels. It is marked by episodes of mood swings ranging from depressive lows to manic highs.
Contact your doctor or seek emergency medical care immediately if you develop a new rash, hives, blistering, peeling skin, or sores while taking Trigil-50 mg Tablet 10's. Although many rashes are mild, lamotrigine can rarely cause serious, life-threatening skin reactions, especially during the first 8 weeks of treatment. Your doctor will usually stop the medicine and determine whether an alternative treatment is needed. Do not restart Trigil-50 mg Tablet 10's unless your doctor specifically advises you to do so
You may experience uncontrollable and quick eye movements, lack of coordination and clumsiness. High doses of Trigil-50 mg Tablet 10's may cause changes in heartbeat rhythm, balance problems, loss of consciousness, fits (convulsions) or coma. If you suspect you have taken more than the recommended dose of Trigil-50 mg Tablet 10's, seek medical help immediately, even if there are no signs of discomfort.
You are recommended to consult your doctor before taking Trigil-50 mg Tablet 10's with other antiepileptic medicines to avoid drug interactions.
Take Trigil-50 mg Tablet 10's as advised by the doctor. It can be taken with or without food. Swallow it as whole with a glass of water. Do not break, crush or chew it.
Yes, you can take Trigil-50 mg Tablet 10's if you have symptoms of depression. In fact, Trigil-50 mg Tablet 10's is used to prevent depression. However, do not self-medicate. Use Trigil-50 mg Tablet 10's only if prescribed by a doctor.
It is highly recommended to limit or avoid alcohol while taking this medication. Alcohol can increase side effects like drowsiness, dizziness, and poor coordination, and can also trigger seizures. Talk to your doctor about your alcohol consumption.
Yes, there can be an interaction. Birth control pills can lower the level of Trigil-50 mg Tablet 10's in your blood, and Trigil-50 mg Tablet 10's can sometimes affect how well your birth control works. You may need dose adjustments or alternative contraceptive methods. Talk to your doctor to find the best option for you.
If you are pregnant or planning to become pregnant, you must weigh the risks and benefits of taking this medication with your physician. Uncontrolled seizures can also pose risks to both you and your baby. Talk to your doctor immediately if you suspect you are pregnant.
Yes, drowsiness and fatigue are common side effects of this medication, especially when you first start taking it or when your dose is increased. Avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if the sleepiness persists or interferes with your daily activities.

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Country of origin

India

Manufacturer/Marketer address

2ND FLOOR, SHOP-S/8, SY NO-153/6, SILVER POINT, OPP. VIDHYA BHARTI SCHOOL, BHATAR ROAD, SURAT, Gujarat, India - 395007
Other Info - TRI2244

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