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Triluma Cream 15 gm
Triluma Cream 15 gm
Triluma Cream 15 gm

Triluma Cream is used to treat melasma (dark brown patches on the skin). It blocks the production of certain chemical messengers that make the skin red, swollen, and itchy, decreasing the amount of melanin (a skin pigment) and increasing the renewal of skin cells. In some cases, this medicine may cause side effects such as application site reactions (burning, irritation, itching, and redness).

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUOCINOLONE ACETONIDE-0.01%W/W+HYDROQUINONE-4%W/W+TRETINOIN-0.05%W/W

Manufacturer/Marketer :

Galderma India Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Triluma Cream

Triluma Cream is primarily used to treat melasma (dark brown patches on the skin). Melasma, also known as chloasma, is a common skin condition that causes brown patches on the face.

Triluma Cream contains Fluocinolone acetonide, Hydroquinone and Tretinoin. Fluocinolone acetonide blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Hydroquinone decreases the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin increases the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers.

Some people may experience application site reactions (burning, irritation, itching, and redness). Most of these side effects of Triluma Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Triluma Cream or any other medicines, please tell your doctor. If you are pregnant, a nursing mother or planning for pregnancy, it is advised to consult a doctor before using Triluma Cream. Triluma Cream is not recommended for children below 12 years of age . Do not apply Triluma Cream to ulcerated skin or wounds.

Uses of Triluma Cream

Triluma Cream is used for the treatment of melasma. The detailed uses of Triluma Cream include:

  • Treatment of melasma: Triluma Cream is prescribed to lighten dark patches of skin (melasma) on the face, especially on the cheeks, forehead, and upper lip.
  • Skin lightening and tone correction: Triluma Cream works by reducing the formation of melanin, helping fade hyperpigmented areas.
  • Anti-inflammatory action: Fluocinolone acetonide, a mild corticosteroid, reduces inflammation, redness, and irritation associated with melasma.
  • Cell turnover enhancement: Triluma Cream promotes skin cell turnover, helping remove pigmented, damaged skin and enhancing the penetration of other ingredients.

Key Benefits

  • Triluma Cream contains Fluocinolone acetonide (steroid), Hydroquinone (skin lightening or bleaching agent) and Tretinoin (a form of Vitamin A or retinoids) used to treat melasma.
  • Fluocinolone acetonide is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.
  • Hydroquinone belongs to the class of skin lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin.
  • Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of skin’s outer layers.
Side effects of Triluma Cream 15 gm
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Moisturize frequently with thick, broad-spectrum moisturizers containing sunscreen.
  • Use warm water for short baths, and gentle cleansers.
  • Pat dry and apply moisturizer immediately.
  • Use a humidifier to add moisture to the air, and choose breathable fabrics like cotton and silk.
  • Wash clothes with fragrance-free detergents to minimize irritation.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Apply Triluma Cream on the clean and dry affected area as your doctor advises.
  • Wash your hands after using Triluma Cream unless the treatment is for your hands.

How Triluma Cream Works

Triluma Cream contains three medicines, namely: Fluocinolone acetonide (steroid), Hydroquinone (skin lightening or bleaching agent), and Tretinoin (a form of Vitamin A or retinoids). Fluocinolone acetonide is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Hydroquinone belongs to the class of skin-lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin's outer layers.
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Alcohol

Consult your doctor

The interaction of alcohol with Triluma Cream is unknown. Please consult a doctor before consuming alcohol while using Triluma Cream.

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Pregnancy

Caution

The safety of Triluma Cream in pregnant women is unknown and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Triluma Cream is excreted in human milk. Please consult a doctor before using Triluma Cream while breastfeeding.

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Driving

Safe if prescribed

Triluma Cream usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of Triluma Cream in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Triluma Cream in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Triluma Cream is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

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Heart

Caution

Limited information was available regarding the use of Triluma Cream in patients with heart problems. Please consult your doctor before using Triluma Cream.

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Geriatrics

Caution

Triluma Cream should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Triluma Cream.

What if I have taken an overdose of Triluma Cream

Though overdose is unlikely due to low systemic absorption, it is advised to avoid exceeding the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

  • Avoid sun exposure while using Triluma Cream as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem, though it doesn’t clear spots. Take a shower immediately after finishing the exercise.
  • Wear a wide-brimmed hat to protect your face from sun exposure.
  • Avoid using skin products that cause irritation, such as skin cleansers or shampoos, harsh soaps, hair removers or waxes, hair colours or permanent chemicals, skin products with astringents, lime, spices, or alcohol.

Health Queries

Have a query?

How Soon It Starts Working

  • The time required for Triluma Cream to start to work: Triluma Cream ideally shows its action within 2 to 4 weeks of consistent use.
  • The time for which the effects of Triluma Cream last: The duration of action for Triluma Cream is clinically unknown.

What if you forget to take Triluma Cream

If you miss a dose of Triluma Cream, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not apply a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Triluma Cream out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are allergic to Triluma Cream or any other medicines, please tell your doctor.
  • If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Triluma Cream.
  • Triluma Cream is not recommended for children below 12 years of age.
  • Do not apply Triluma Cream to ulcerated skin or wounds.
  • Avoid sun exposure while using Triluma Cream as it may make the skin more sensitive to sunlight and cause sunburn.
  • Do not cover or wrap the treated area with a bandage unless advised by your doctor.
  • Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Triluma Cream catches fire and burns easily.
  • If you have a sulfite allergy, asthma, have rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, diabetes, Cushing syndrome, glucosuria, inform your doctor before using Triluma Cream.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: No interactions found.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: No interactions found.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Triluma Cream is used to treat melasma (dark brown patches on the skin).
Triluma Cream contains three medicines, namely: Fluocinolone acetonide (steroid), Hydroquinone (skin lightening or bleaching agent), and Tretinoin (a form of Vitamin A or retinoids). Fluocinolone acetonide is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Hydroquinone belongs to the class of skin lightening agents that work by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of skin's outer layers.
Triluma Cream causes common side effects at the application site (burning, irritation, itching, and redness). Most of these side effects of Triluma Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Triluma Cream may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
Yes, Triluma Cream may cause skin irritation, burning sensation, or itching at the site of application in rare cases. However, if the irritation persists or worsens, stop using Triluma Cream and consult a doctor.
You are recommended to use Triluma Cream for as long as your doctor has prescribed it. However, avoid using Triluma Cream for more than 6 to 8 weeks without a doctor's advice.
To use Triluma Cream, clean the affected area and pat it dry. Then, apply Triluma Cream to the affected area as advised by your doctor and gently rub it in.
Triluma Cream is not recommended for children under 12 years old, as its safety and effectiveness in this age group have not been established. If your child requires treatment, consult your paediatrician for an appropriate suggestion.
If Triluma Cream gets in your eyes, act fast! Rinse your eyes with water for a few minutes. Remove contact lenses if you have them. Gently pat the area, don't rub. If your eyes still hurt or feel uncomfortable, see a doctor. By acting quickly, you can help make your eyes feel better.
Triluma Cream is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
Store Triluma Cream in its original container, keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects such as skin irritation, redness, and peeling.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Hydroquinone Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Mayo Clinic Staff. Drg 20060789 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Tretinoin Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Fluocinolone acetonide, hydroquinone, and tretinoin [Prescribing Information]. 2014. [Accessed on 29 Apr. 2019] Check here
  6. Fluocinolone acetonide + hydroquinone + tretinoin [Prescribing Information]. 2013. [Accessed on 29 Apr. 2019] Check here
  7. CiplaMed CiplaMed. [Accessed on 14 Aug. 2024]Check here

Country of origin

INDIA

Manufacturer/Marketer address

GALDERMA INDIA Pvt. Ltd., Lotus Corporate Park, D Wing Unit 801\802 , Off Western Express Highway, Goregaon (East), Mumbai 400 063, India, Phone: +91 22 40331818
Other Info - TRI1300

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