Trimacsart Tablet 10's
MRP ₹147.5
(Inclusive of all Taxes)
₹22.1 Cashback (15%)
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Manufacturer/Marketer :
Macleods Pharmaceuticals Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About Trimacsart Tablet
Trimacsart Tablet is primarily given for the treatment of hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high.
Trimacsart Tablet is a combination of Telmisartan, Amlodipine, and Hydrochlorothiazide, which works by blocking the action of certain substances that are responsible for tightening the blood vessels. This medicine helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke.
In some cases, Trimacsart Tablet may cause common side effects like ankle swelling, headache, dizziness, tiredness, taste change, muscle weakness, dry mouth, and extreme thirst. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, reach out to your doctor.
You can take Trimacsart Tablet with or without food as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will guide you on how to take the medicine based on your medical condition.
Don't stop taking Trimacsart Tablet without your doctor's advice. Sudden stopping of Trimacsart Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. It is advised to drink plenty of fluids while taking this medicine to overcome dry mouth and extreme thirst.
Uses of Trimacsart Tablet
Trimacsart Tablet is used in the treatment of high blood pressure (hypertension). The detailed uses of Trimacsart Tablet are as follows:
- Hypertension Management: Trimacsart Tablet is primarily used to help lower high blood pressure, which can reduce the risk of heart disease and stroke.
- Heart Failure Treatment: Trimacsart Tablet may be prescribed to patients who are experiencing heart failure symptoms, helping to improve heart function and reduce strain on the heart.
- Kidney Protection: Trimacsart Tablet can be utilized to protect the kidneys, especially in patients with high blood pressure and diabetes, by lowering blood pressure and improving kidney function over time.
- Combination Therapy: Trimacsart Tablet can be used in combination with other antihypertensive medications to achieve better control of blood pressure in patients requiring multiple therapies.
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Directions for Use
- Trimacsart Tablet can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Trimacsart Tablet as a whole with a glass of water.
- Do not crush, break, or chew it.
Medicinal Benefits
- When you take Trimacsart Tablet , it works by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body.
- Trimacsart Tablet helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke.
- It helps remove the extra water and certain electrolytes from the body through urine.
- Oedema may occur in cases of high blood pressure, where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to its swelling. Trimacsart Tablet is also used in the treatment of oedema.
How Trimacsart Tablet Works
Trimacsart Tablet is a combination of Telmisartan, Amlodipine, and Hydrochlorothiazide which are antihypertensive medicines. Telmisartan works by blocking the action of certain substances that are responsible for tightening the blood vessels. It allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body. Amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels. Hydrochlorothiazide is a diuretic and its function is to remove extra water and certain electrolytes from the body through urine. Trimacsart Tablet helps to lower high blood pressure thus reducing the chances of future heart attack and stroke.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Trimacsart Tablet
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
- Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
- Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
- Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
- Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
What if I have taken an overdose of Trimacsart Tablet
Do not take more than the prescribed dose of Trimacsart Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
Drug Warnings
- Avoid taking Trimacsart Tablet if you are allergic to any of the ingredients present in it.
- Trimacsart Tablet should be used with extreme caution in patients with liver, kidney, cardiovascular diseases and diabetic patients. Use only if the potential benefit justifies the potential risk.
- Trimacsart Tablet is not recommended for use in children below 18 yaers of age.
- Inform your doctor if you are pregnant or breastfeeding before starting treatment with Trimacsart Tablet .
- It is advised not to take more than the recommended dose of medicine.
Drug-Drug Interactions
AmlodipineDantrolene
Critical
Critical
Drug-Drug Interactions
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AmlodipineDantrolene
Critical
How does the drug interact with Trimacsart Tablet:
Using Trimacsart Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Trimacsart Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Using Trimacsart Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Trimacsart Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Trimacsart Tablet:
Co-administration of Aliskiren with Trimacsart Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).
How to manage the interaction:
Taking Trimacsart Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Aliskiren with Trimacsart Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).
How to manage the interaction:
Taking Trimacsart Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Critical
How does the drug interact with Trimacsart Tablet:
Taking Cisapride and Trimacsart Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Trimacsart Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Trimacsart Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Trimacsart Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Trimacsart Tablet:
Taking Dofetilide and Trimacsart Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Trimacsart Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Trimacsart Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Trimacsart Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Trimacsart Tablet:
Co-administration of Tizanidine and Trimacsart Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Co-administration of Tizanidine and Trimacsart Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Severe
How does the drug interact with Trimacsart Tablet:
Coadministration of Trimacsart Tablet with itraconazole may significantly raise the blood levels and effects of Trimacsart Tablet.
How to manage the interaction:
Trimacsart Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
Coadministration of Trimacsart Tablet with itraconazole may significantly raise the blood levels and effects of Trimacsart Tablet.
How to manage the interaction:
Trimacsart Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
Severe
How does the drug interact with Trimacsart Tablet:
Using Trimacsart Tablet and rifabutin together may lower Trimacsart Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Trimacsart Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
Using Trimacsart Tablet and rifabutin together may lower Trimacsart Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Trimacsart Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Trimacsart Tablet:
Coadministration of lemborexant and Trimacsart Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Coadministration of lemborexant and Trimacsart Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Trimacsart Tablet:
Co-administration of Trimacsart Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).
How to manage the interaction:
There may be a possibility of interaction between Trimacsart Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
Co-administration of Trimacsart Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).
How to manage the interaction:
There may be a possibility of interaction between Trimacsart Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Trimacsart Tablet:
Using Trimacsart Tablet and mitotane together may drastically lower Trimacsart Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Trimacsart Tablet and mitotane together may drastically lower Trimacsart Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Trimacsart Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+TELMISARTAN-40MGPotassium rich foods
Moderate
Drug-Food Interactions
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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+TELMISARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Trimacsart Tablet with can cause high levels of potassium in your blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Trimacsart Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Trimacsart Tablet with can cause high levels of potassium in your blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Trimacsart Tablet.
Diet & Lifestyle Advise
- Keep your weight under control with BMI 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
- Avoid stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.
- Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
Habit Forming
No
Therapeutic Class
ANTI- HYPERTENSIVES
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Alcohol
Unsafe
You are recommended not to consume alcohol along with Trimacsart Tablet to avoid unpleasant side-effects.
Pregnancy
Consult your doctor
Trimacsart Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.
Breast Feeding
Consult your doctor
Trimacsart Tablet is not recommended during breast-feeding. However, your doctor may prescribe it for you during breast-feeding if he/she feels that the benefit to you outweighs the risk.
Driving
Unsafe
It is advised not to drive after taking Trimacsart Tablet as it usually causes drowsiness and affects the driving ability.
Liver
Caution
Trimacsart Tablet is advised to be taken with caution, especially if you have or have had a history of liver disease.
Kidney
Unsafe
It is not recommended in patients with chronic kidney disease (severe renal impairment). The safety and effectiveness in patients with renal impairment have not been established.
Children
Consult your doctor
Trimacsart Tablet is not recommended for use in children as the safety and efficacy are not established.
Heart
Trimacsart Tablet is safe for use in heart patients if prescribed by the physician. Please inform your doctor about any existing heart problems before using Trimacsart Tablet .
Geriatrics
Caution
Trimacsart Tablet is safe for use if recommended by the physician in geriatric patients. Please consult your physician.
FAQs
Country of origin
India
Manufacturer/Marketer address
Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - TRI0780
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Reference
- https://1.
- https://www.ema.europa.eu/documents/product-information/twynsta-epar-product-information_en.pdf2.
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf3.
- https://www.accessdata.fda.gov/drugsatfda_docs/label/1998/20850lbl.pdf4.
- https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Telsite-AM-H-PI-June-2018.pdf?la=en
Overview of Trimacsart Tablet 10's
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