Triolmezest Tablet 10's
MRP ₹218
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Manufacturer/Marketer :
Sun Pharmaceutical Industries Ltd
Consume Type :
ORAL
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About Triolmezest Tablet
Triolmezest Tablet is primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the force of blood against the artery walls is high.
Triolmezest Tablet is a combination of Olmesartan, Amlodipine, and Hydrochlorothiazide. Olmesartan blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide removes extra water/fluid and certain electrolyte overload from the body.
The most common side effects of Triolmezest Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor.
If you are pregnant or breastfeeding, do not take Triolmezest Tablet as it is a category D pregnancy drug and may harm the baby. Do not use Triolmezest Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine.
Uses of Triolmezest Tablet
Triolmezest Tablet is used in the treatment of high blood pressure (hypertension). The detailed uses of Triolmezest Tablet are as follows:
- Lowers High Blood Pressure effectively: Triolmezest Tablet used to relax blood vessels, reduce fluid retention, and lower resistance in the arteries, helping to bring down high blood pressure.
- Prevents Heart and Kidney Complications: By maintaining optimal blood pressure levels, Triolmezest Tablet helps to reduce the risk of stroke, heart attack, kidney damage, and other related complications.
- Improves Blood Flow and Reduces Swelling: Triolmezest Tablet promotes better circulation and reduces swelling or fluid buildup in the body due to its diuretic component.
Health Queries
Dr S Aneela
M. Pharm (Pharmacology)., PhD
A heavy head and weakness can be linked to vitamin B12 and D deficiency, high cholesterol, or general fatigue rather than Triolmezest itself. Focus on a balanced diet, regular light exercise, good sleep, and sunlight exposure. Follow up with your doctor to correct vitamin deficiencies and manage cholesterol for overall better health.
Dr Y Thulasi
Pharm-D (Post baccalaureate)
If your blood pressure is under control, triolmezest is a typical treatment for excessive blood pressure. If your readings are stable and you are not experiencing any adverse effects, such as swelling or dizziness, there is no need to make any changes. Your doctor may change the dosage or medications if your blood pressure stays elevated or you feel ill.
Have a query?
Directions for Use
- Triolmezest Tablet can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Triolmezest Tablet as a whole with a glass of water.
- Do not chew, crush, or break it.
Medicinal Benefits
- Triolmezest Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.
- Triolmezest Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide.
- Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels.
- Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body.
- Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Triolmezest Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.
How Triolmezest Tablet Works
Triolmezest Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Triolmezest Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.<
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Triolmezest Tablet
Here are the 7 steps to manage Dizziness caused by medication:
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
What if I have taken an overdose of Triolmezest Tablet
Do not take more than the prescribed dose of Triolmezest Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
Drug Warnings
- Do not use Triolmezest Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria).
- If you have diabetes and are taking Triolmezest Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor.
- Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
- Triolmezest Tablet may pass into breast milk, so before starting Triolmezest Tablet , either you need to stop nursing or you should not take Triolmezest Tablet while breastfeeding.
- Please inform your doctor before surgery if you are taking Triolmezest Tablet , as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
- Avoid potassium salt or its substitute intake while using Triolmezest Tablet to avoid any electrolyte imbalance.
- Triolmezest Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Triolmezest Tablet and are breastfeeding.
- In rare cases, Triolmezest Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-colored urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor.
- Try not to stop taking this medicine on your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase the risk of heart disease and stroke.
Drug-Drug Interactions
Critical
AmlodipineDantrolene
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Triolmezest Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).
How to manage the interaction:
Taking Triolmezest Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).
How to manage the interaction:
Taking Triolmezest Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Triolmezest Tablet:
Using Triolmezest Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Triolmezest Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Using Triolmezest Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Triolmezest Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Triolmezest Tablet:
Taking Cisapride and Triolmezest Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Triolmezest Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Triolmezest Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Triolmezest Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Triolmezest Tablet:
Taking Dofetilide and Triolmezest Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Triolmezest Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Triolmezest Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Triolmezest Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilCaptopril
Severe
How does the drug interact with Triolmezest Tablet:
When Triolmezest Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
When Triolmezest Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilpotassium phosphate
Severe
How does the drug interact with Triolmezest Tablet:
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Triolmezest Tablet:
Triolmezest Tablet when combined with benazepril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Triolmezest Tablet when combined with benazepril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Triolmezest Tablet:
Coadministration of Triolmezest Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Coadministration of Triolmezest Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Triolmezest Tablet:
Using Triolmezest Tablet with Potassium chloride may increase Potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Using Triolmezest Tablet with Potassium chloride may increase Potassium levels in the blood.
How to manage the interaction:
Although taking Triolmezest Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium iodide
Severe
How does the drug interact with Triolmezest Tablet:
Coadministration of Triolmezest Tablet with potassium iodide may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Although taking Triolmezest Tablet together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of Triolmezest Tablet with potassium iodide may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Although taking Triolmezest Tablet together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate
Drug-Food Interactions
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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Triolmezest Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Triolmezest Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Triolmezest Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Triolmezest Tablet.
Diet & Lifestyle Advise
- Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
- Keep your weight under control with a BMI of 19.5-24.9.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Be mindful of salt; consume no more than 2,300 mg each day.
- Limit or avoid alcohol consumption.
- Quitting smoking is the best strategy to lower the risk of heart disease.
Habit Forming
No
Therapeutic Class
ANTI- HYPERTENSIVES
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Alcohol
Unsafe
You are recommended not to consume alcohol and Triolmezest Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.
Pregnancy
Unsafe
Triolmezest Tablet is not recommended during pregnancy as it contains Olmesartan, which is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).
Breast Feeding
Unsafe
Triolmezest Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Triolmezest Tablet or stop taking Triolmezest Tablet .
Driving
Caution
Drive with caution; Triolmezest Tablet usually causes drowsiness and affects driving ability.
Liver
Caution
Triolmezest Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will change the dosage depending on your medical condition and your reaction to treatment.
Kidney
Caution
Triolmezest Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Children
Caution
Efficacy and safety of Triolmezest Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.
Heart
Caution
Triolmezest Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Triolmezest Tablet .
Geriatrics
Caution
Triolmezest Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Triolmezest Tablet .
FAQs
Country of origin
India
Manufacturer/Marketer address
Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TRI0590
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