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Triolsar 40 HS Tablet is used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke. It works by relaxing and widening blood vessels, improving blood flow, and lowering fluid overload. In some cases, this medicine may cause side effects such as dizziness, headache, stomach upset, or tiredness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Triolsar 40 HS Tablet

Triolsar 40 HS Tablet is a prescription medication used to treat high blood pressure (hypertension). It is typically prescribed when a single medication is not enough to control blood pressure levels. By lowering high blood pressure, it helps prevent serious cardiovascular events like strokes and heart attacks.

This medicine is usually taken once daily, and it is important to take it consistently at the same time every day to maintain steady blood pressure levels. You can take this tablet with or without food. Along with taking this medicine, incorporating lifestyle changes such as eating a low-salt diet and getting regular exercise can significantly improve your results.

Some people taking Triolsar 40 HS Tablet may experience mild side effects like dizziness, ankle swelling, or tiredness as their body adjusts. While these are often temporary, you should consult your doctor immediately if you experience severe dizziness, muscle weakness, or signs of an allergic reaction.

Talk to your doctor before starting Triolsar 40 HS Tablet if you have kidney problems, liver damage, diabetes, or heart conditions. Pregnant women must not take this medicine, as it can cause serious harm or even death to an unborn baby.

This medicine can interact with alcohol, smoking, and other medications, such as certain pain relievers or potassium supplements, which can alter its effectiveness or cause dangerous drops in blood pressure. If you are breastfeeding, elderly, or planning a surgery, it is highly recommended to consult your healthcare provider to ensure this medication is safe for you.

Uses of Triolsar 40 HS Tablet

Your doctor may prescribe Triolsar 40 HS Tablet to prevent or treat: 

  • High Blood Pressure (Hypertension): Triolsar 40 HS Tablet helps by relaxing blood vessels and reducing excess fluid in the body, which effectively lowers blood pressure to a safer, manageable range.

Key Benefits

While high blood pressure often has no visible symptoms, using Triolsar 40 HS Tablet provides crucial, quiet protection for your body. Here is how this medicine helps you in the real world:

  • Convenience of a Single Tablet: By combining three different blood pressure-lowering agents into one pill, Triolsar 40 HS Tablet reduces the number of daily tablets you need to take, making it easier to stick to your treatment plan.
  • Highly Effective Blood Pressure Control: Because the components target different pathways in your body, they work together to provide more consistent and robust blood pressure reduction than single-ingredient therapies.
  • Protection for Your Heart and Organs: Keeping your blood pressure in a healthy range reduces the workload on your heart, significantly lowering your long-term risk of heart attacks, strokes, and kidney damage.
Side effects of Triolsar 40 HS Tablet
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Triolsar 40 HS Tablet can be taken with food to prevent stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Triolsar 40 HS Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Triolsar 40 HS Tablet Works

Triolsar 40 HS Tablet works through three different mechanisms that target different parts of your cardiovascular system to lower blood pressure effectively: Amlodipine is a calcium channel blocker. It reduces the movement of calcium into the muscle cells of the blood vessels. This helps the blood vessels relax and widen, allowing blood to flow more easily and reducing the effort needed by the heart to pump blood. Olmesartan medoxomil is an angiotensin receptor blocker (ARB). It blocks the action of angiotensin II, a natural substance that causes blood vessels to narrow. This helps the blood vessels remain relaxed and open, lowering blood pressure. Chlorthalidone is a diuretic, also known as a water pill. It helps the kidneys remove extra salt and water from the body through urine. This reduces the amount of fluid in the bloodstream and helps lower blood pressure.
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Alcohol

Unsafe

Avoid consumption of alcohol with Triolsar 40 HS Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

Triolsar 40 HS Tablet is not recommended for pregnant women as it may cause serious harm to the unborn baby. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Triolsar 40 HS Tablet may be excreted in human milk and harm the baby. Therefore, avoid taking Triolsar 40 HS Tablet if you are breastfeeding and consult a doctor.

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Driving

Caution

Triolsar 40 HS Tablet may cause dizziness or drowsiness in some people. Therefore, avoid driving if you feel dizzy or drowsy after taking Triolsar 40 HS Tablet .

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Liver

Caution

Take Triolsar 40 HS Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Triolsar 40 HS Tablet if you have severe liver disease.

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Kidney

Caution

Take Triolsar 40 HS Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Triolsar 40 HS Tablet if you have severe kidney disease.

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Children

Unsafe

Triolsar 40 HS Tablet is not recommended for children below 18 years as safety and effectiveness is not established.

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Heart

Caution

Triolsar 40 HS Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Triolsar 40 HS Tablet .

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Geriatrics

Caution

Triolsar 40 HS Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Triolsar 40 HS Tablet .

What if I have taken an overdose of Triolsar 40 HS Tablet

If you or someone else takes more than the prescribed dose of Triolsar 40 HS Tablet , seek emergency medical care immediately. An overdose can cause a dangerous drop in blood pressure, a very fast or slow heart rate, and severe dizziness. Keep the medicine pack with you so the healthcare providers know exactly what was taken.

Diet & Lifestyle Advise

  • Reduce your sodium intake: Limit salt in your meals and avoid processed foods, as high sodium levels make your body hold onto water, raising your blood pressure and lowering the effectiveness of Triolsar 40 HS Tablet .
  • Stay consistently hydrated: Since this medication helps remove excess fluid, drink a moderate, healthy amount of water daily. Avoid sudden increases or decreases in fluid intake unless advised by your doctor.
  • Manage your potassium intake: This medicine can alter potassium levels in your blood. Consult your doctor before using salt substitutes (which often contain potassium) or making major changes to your intake of potassium-rich foods like bananas or leafy greens.
  • Limit alcohol consumption: Avoid or significantly limit alcohol while taking this medicine. Alcohol can worsen dizziness and cause your blood pressure to drop too low.
  • Move carefully when standing up: To prevent lightheadedness, rise slowly from a sitting or lying position, especially when you first start taking this medicine or after gradually increasing doses.
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How Soon It Starts Working

The time required for Triolsar 40 HS Tablet to start to work: Triolsar 40 HS Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Triolsar 40 HS Tablet last: The effect of Triolsar 40 HS Tablet lasts for 24 to 72 hours.

What if you forget to take Triolsar 40 HS Tablet

If you miss a dose of Triolsar 40 HS Tablet , take it as soon as you remember on that day. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed tablet. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

• Store Triolsar 40 HS Tablet at room temperature, strictly between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Check your blood pressure: Monitor your blood pressure regularly at home and keep a record to share with your doctor.
  • Attend regular blood tests: Your doctor may check your kidney function and electrolyte levels, including potassium and sodium, during treatment.
  • Do not stop treatment on your own: Continue taking Triolsar 40 HS Tablet even if you feel well. Consult your doctor before stopping or changing your treatment.
  • Protect your skin from sunlight: Chlorthalidone may make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing when outdoors.
  • Inform your healthcare team: Tell your doctor, dentist, or surgeon that you are taking Triolsar 40 HS Tablet before any procedure.
     

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Triolsar 40 HS Tablet and require closer monitoring or dose adjustments:

  • Lithium: Taking this combination medicine with lithium can increase lithium levels in your blood, raising the risk of lithium toxicity.
  • NSAIDs (like ibuprofen or naproxen): Using these pain relievers regularly can reduce the blood pressure-lowering effect of Triolsar 40 HS Tablet and significantly increase the risk of kidney damage.
  • Potassium supplements: Combining this medicine with potassium supplements or potassium-sparing diuretics can cause dangerously high potassium levels in your blood.
  • Other blood pressure medications: Taking this alongside other heart or blood pressure drugs can lead to an additive effect, causing excessively low blood pressure.
Olmesartan medoxomil + Amlodipine + chlorthalidoneAliskiren
Critical
Olmesartan medoxomil + Amlodipine + chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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Olmesartan medoxomil + Amlodipine + chlorthalidoneAliskiren
Critical
How does the drug interact with Triolsar 40 HS Tablet:
Using aliskiren with Olmesartan medoxomil and Amlodipine and chlorthalidone may increase the risk of serious side effects.

How to manage the interaction:
Taking Olmesartan medoxomil and Amlodipine and chlorthalidone with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience vomiting, weakness, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneCisapride
Critical
How does the drug interact with Triolsar 40 HS Tablet:
Co-administration of Olmesartan medoxomil and Amlodipine and chlorthalidonel with cisapride may increase the risk or severity of an irregular heart rhythm.

How to manage the interaction:
Taking Olmesartan medoxomil and Amlodipine and chlorthalidonel with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not discontinue the medication without consulting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneAmiodarone
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Coadministration of Olmesartan medoxomil and Amlodipine and chlorthalidone with amiodarone may increase the risk of abnormal heart rhythms.

How to manage the interaction:
Although taking Olmesartan medoxomil and Amlodipine and chlorthalidone with amiodarone may cause an interaction, it is safe to do so if a doctor has prescribed it. If you develop dizziness, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidonepotassium phosphate
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Using potassium phosphate together with Olmesartan medoxomil and Amlodipine and chlorthalidonel may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Amlodipine and chlorthalidonel with potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience vomiting, a weak pulse, or a slow or irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneDolasetron
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Using dolasetron together with Olmesartan medoxomil and Amlodipine and chlorthalidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Olmesartan medoxomil and Amlodipine and chlorthalidone with Dolasetron, but it can be taken if prescribed by a doctor. If you experience dizziness or irregular heartbeat, call a doctor right away. Do not stop using any medications without a doctor's advice.
Olmesartan medoxomil + Amlodipine + chlorthalidoneZiprasidone
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Co-administration of Olmesartan medoxomil and Amlodipine and chlorthalidone with ziprasidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, Olmesartan medoxomil, and Amlodipine and chlorthalidone can be taken with ziprasidone if prescribed by the doctor. However, consult a doctor if you experience dizziness, shortness of breath, muscle pain, or vomiting. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneRifapentine
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Coadministration of Olmesartan medoxomil and Amlodipine and chlorthalidone with Rifapentine may significantly reduce the blood levels of amlodipine, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Olmesartan medoxomil and Amlodipine and chlorthalidone with Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneAminolevulinic acid
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Co-administration of Aminolevulinic acid with Olmesartan medoxomil and Amlodipine and chlorthalidone may increase the risk of severe sunburn.

How to manage the interaction:
Taking Olmesartan medoxomil and Amlodipine and chlorthalidone with Aminolevulinic acid together can result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneBenazepril
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Taking Olmesartan medoxomil and Amlodipine and chlorthalidone with benazepril may increase the risk of side effects.

How to manage the interaction:
Although taking Olmesartan medoxomil and Amlodipine and chlorthalidone with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + Amlodipine + chlorthalidoneCarbamazepine
Severe
How does the drug interact with Triolsar 40 HS Tablet:
Coadministration of Olmesartan medoxomil and Amlodipine and chlorthalidone with carbamazepine together may significantly reduce amlodipine blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Olmesartan medoxomil and Amlodipine and chlorthalidone with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability of Triolsar 40 HS Tablet . Important interactions include:

  • Grapefruit and Grapefruit Juice: Avoid grapefruit products, as they can interfere with how your body breaks down certain components of Triolsar 40 HS Tablet , increasing the risk of side effects like severe dizziness.
  • Salt substitutes: Avoid using potassium-containing salt substitutes without consulting your doctor, as they can cause potassium to build up to unsafe levels in your body.
AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Apricots, Avocado, Bananas, Beans, Beetroot, Broccoli, Coconut Water, Lentils, Orange Juice, Oranges, Potatoes, Raisins, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Yogurt

How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Olmesartan medoxomil, Amlodipine, and chlorthalidone may cause high levels of potassium in blood. Avoid potassium-containing salt substitutes while being treated with Olmesartan medoxomil, Amlodipine, and chlorthalidone.

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Habit Forming

No

Therapeutic Class

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FAQs

Triolsar 40 HS Tablet is used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults.
Triolsar 40 HS Tablet contains Amlodipine, Chlorthalidone and Olmesartan medoxomil. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relaxes and widens blood vessels. Thus, Triolsar 40 HS Tablet lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.
Triolsar 40 HS Tablet may increase potassium levels in the blood. Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium such as bananas, sweet potatoes, nuts and noni juice with Triolsar 40 HS Tablet as it may result in hyperkalaemia (high levels of potassium in the blood) and cause severe adverse effects such as irregular heartbeat, muscle paralysis and kidney failure. Also, avoid taking Triolsar 40 HS Tablet with grapefruit juice as it increases the levels of Triolsar 40 HS Tablet in blood.
Triolsar 40 HS Tablet may cause dizziness in some patients. Therefore, if you feel dizzy after taking Triolsar 40 HS Tablet , avoid driving or operating heavy machinery.
You are not recommended to take simvastatin with Triolsar 40 HS Tablet as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking other medicines with Triolsar 40 HS Tablet .
You are not recommended to stop taking Triolsar 40 HS Tablet without consulting your doctor even if you find symptomatic relief as it may worsen the condition. Therefore, take Triolsar 40 HS Tablet for as long as your doctor has prescribed it and if you experience any difficulty while using Triolsar 40 HS Tablet , please consult your doctor.
The side effects of Triolsar 40 HS Tablet include headache, dizziness, stomach upset, swelling of ankles, feet, hands, arms, or legs, low or high blood pressure, or tiredness. Most of these side effects gradually resolve over time. However, consult the doctor if any of these symptoms persist or worsen.
No, you must not take this medication during pregnancy. It can cause serious harm or death to an unborn baby, especially if taken during the second and third trimesters. If you suspect you are pregnant, stop taking the medicine immediately and contact your healthcare provider. Talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can cause your blood pressure to drop too low, leading to severe dizziness, lightheadedness, or fainting. Talk to your doctor.
This medication contains a mild diuretic, or water pill, which helps your body eliminate excess salt and fluid through your urine. Taking your dose in the morning can help prevent this effect from disrupting your sleep. Talk to your doctor.
Take the missed tablet as soon as you remember on that day. If it is almost time for your next scheduled dose, skip the missed one and continue your normal routine. Never take two tablets at once to make up for a missed dose. Talk to your doctor.
You should avoid using salt substitutes that contain potassium while taking this medicine. This combination medication can affect how your kidneys handle potassium, and consuming extra potassium can lead to dangerously high levels in your blood. Talk to your doctor.
Mild ankle or foot swelling is a common, recognised side effect of this type of blood pressure medication. Try keeping your feet elevated when sitting, but if the swelling becomes painful, worsens rapidly, or is accompanied by breathing difficulties, contact your healthcare provider immediately. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TRI1001
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