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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tripin OM 40 Tablet is used to lower high blood pressure (hypertension). It dilates (widens) and relaxes narrowed blood vessels and improves blood flow and makes the heart can pump blood more efficiently. Also, it works by removing extra water/fluid and certain electrolyte overload from the body. Thus, it helps to lower high blood pressure and fluid overload, relieve chest pain (angina) and other conditions caused by coronary artery disease. It also reduces the future risk of a heart attack and stroke. In some cases, you may experience side effects such as nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness and decreased blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tripin OM 40 Tablet

Tripin OM 40 Tablet is an 'anti-hypertensives' medication primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat and other complications.

Tripin OM 40 Tablet is a combination of three medicines: Amlodipine, Hydrochlorothiazide and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Tripin OM 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.

You can take Tripin OM 40 Tablet with food or without food with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness and decreased blood pressure. Most of these side effects of Tripin OM 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not take this Tripin OM 40 Tablet if you have diabetes mellitus, liver and kidney problems and low blood pressure. If you notice unexplained muscle pain, dark colour urine, tenderness or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. If you have any allergy to amlodipine, hydrochlorothiazide, and olmesartan, then do not take this Tripin OM 40 Tablet . Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes.

Uses of Tripin OM 40 Tablet

Treatment of Hypertension (high blood pressure).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tripin OM 40 Tablet is a combination of three medicines: Amlodipine, Hydrochlorothiazide, and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Tripin OM 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.

How Tripin OM 40 Tablet Works

Tripin OM 40 Tablet is a combination of three medicines: Amlodipine, Hydrochlorothiazide and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Tripin OM 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tripin OM 40 Tablet

  • Nausea
  • Stuffy nose/sore throat
  • Upset stomach
  • Diarrhoea
  • Headache
  • Dizziness
  • High level of uric acid
  • Electrolyte imbalance
  • Dehydration.
  • Decreased blood pressure

What if I have taken an overdose of Tripin OM 40 Tablet

Do not take more than the prescribed dose of Tripin OM 40 Tablet as it may cause overdose. The symptoms of overdose include fainting and severe dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not use Tripin OM 40 Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Tripin OM 40 Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). Tripin OM 40 Tablet may pass into breast milk, so before starting Tripin OM 40 Tablet , either you need to stop nursing or you should not take Tripin OM 40 Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Tripin OM 40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Tripin OM 40 Tablet to avoid any electrolyte imbalance.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
AmlodipineDantrolene
Critical

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Tripin OM 40 Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Tripin OM 40 Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Tripin OM 40 Tablet:
Using Tripin OM 40 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Tripin OM 40 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Tripin OM 40 Tablet:
Taking Dofetilide and Tripin OM 40 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Tripin OM 40 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Tripin OM 40 Tablet:
Taking Cisapride and Tripin OM 40 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Tripin OM 40 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Olmesartan medoxomilPerindopril
Severe
How does the drug interact with Tripin OM 40 Tablet:
Coadministration of Tripin OM 40 Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Tripin OM 40 Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium chloride
Severe
How does the drug interact with Tripin OM 40 Tablet:
Using Tripin OM 40 Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Tripin OM 40 Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTrimethoprim
Severe
How does the drug interact with Tripin OM 40 Tablet:
Taking Tripin OM 40 Tablet with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Tripin OM 40 Tablet with trimethoprim may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilLithium
Severe
How does the drug interact with Tripin OM 40 Tablet:
Taking lithium with Tripin OM 40 Tablet may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Tripin OM 40 Tablet alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop sleepiness, dizziness, confusion, loose stools, vomiting, muscular weakness, muscle incoordination, a shaking sensation, blurred vision, ringing in the ears, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Tripin OM 40 Tablet:
Coadministration of Tripin OM 40 Tablet with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Tripin OM 40 Tablet together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
Olmesartan medoxomilLisinopril
Severe
How does the drug interact with Tripin OM 40 Tablet:
Coadministration of Tripin OM 40 Tablet with lisinopril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Tripin OM 40 Tablet together with lisinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Tripin OM 40 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Tripin OM 40 Tablet.

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are highly antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Elevate your legs or the swollen area on a chair or pillow.
  • Avoid standing or sitting for extended periods.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Tripin OM 40 Tablet Substitute

Substitutes safety advice
  • OLMEWON PLUS 40MG TABLET

    by Others

    16.20per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol and Tripin OM 40 Tablet to avoid unpleasant side effects like drowsiness, dizziness and liver damage.

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Pregnancy

Unsafe

Tripin OM 40 Tablet is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Tripin OM 40 Tablet is known to pass breast milk, but its effect on the baby is not known. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Tripin OM 40 Tablet , or you need to stop takingTripin OM 40 Tablet .

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Driving

Caution

Drive with caution, Tripin OM 40 Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Tripin OM 40 Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

bannner image

Kidney

Caution

Tripin OM 40 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

bannner image

Children

Unsafe

Efficacy and safety of Tripin OM 40 Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harms.

FAQs

Tripin OM 40 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.

Tripin OM 40 Tablet is a combination of three medicines: Amlodipine, Hydrochlorothiazide and Olmesartan. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Tripin OM 40 Tablet lowers fluid overload, raises blood pressure, improves blood flow and reduces the future risk of a heart attack and stroke. On the other hand, Olmesartan is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently.

In case you have missed a dose of Tripin OM 40 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose, taking a double dose of Tripin OM 40 Tablet will lead to low blood pressure.

Do not use Tripin OM 40 Tablet if you are pregnant, planning for pregnancy or unable to urinate. If you have diabetes and taking Tripin OM 40 Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor.

Your doctor will check your blood potassium levels regularly for high levels of potassium. Make sure not to miss any future meetings with the doctor.

You may experience fluid loss or dehydration while using Tripin OM 40 Tablet . To avoid this condition, it is advisable to drink a lot of fluid and water, especially in summer. If you are a kidney patient, please consult a doctor before drinking or increasing any fluid intake.

Yes, the use of a Tripin OM 40 Tablet can make you feel dizzy. This may occur when you suddenly rise from a sitting or lying position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been lying down or sitting.

It is not recommended to use Tripin OM 40 Tablet during pregnancy. This medication can harm the developing baby, especially in the second and third trimesters. Tell your doctor right away if you become pregnant or are planning to become pregnant.

While using Tripin OM 40 Tablet , adopt a diet rich in antioxidants such as blueberries, cherries, and bell peppers, and incorporate natural diuretics like asparagus, beets, and pineapple. Use healthy cooking oils like olive or coconut oil, and avoid refined foods, trans fats, and excessive salt. Maintain a healthy weight with a BMI between 19.5 and 24.9, engage in regular physical activity, and elevate swollen areas when necessary. Minimize prolonged sitting or standing, manage stress through mindfulness, and strengthen relationships with loved ones. Finally, quitting smoking and alcohol is crucial for reducing health risks.

Even if you feel well, consult your doctor before taking Tripin OM 40 Tablet . Feeling better does not mean your condition is fully resolved. This medication helps manage high blood pressure and can prevent serious heart-related issues. Stopping it suddenly may cause your blood pressure to rise again, which could increase the risk of complications like heart attack, stroke, or kidney damage. Always consult your doctor. They will monitor your health and may adjust your treatment plan if necessary.

Tripin OM 40 Tablet should be stored in a cool and dry place, away from moisture and heat. Keep it out of reach of children.

The possible side effects of Tripin OM 40 Tablet include nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalances, dizziness, and low blood pressure. If you experience any of these symptoms, staying hydrated, eating a balanced diet, and resting as needed are essential. If the symptoms do not resolve over time, contact your doctor immediately.

Take Tripin OM 40 Tablet once daily, with or without food, or as directed by your doctor. Swallow the tablet whole with a glass of water. Do not crush, break, or chew it. Always follow your doctor's instructions for optimal effectiveness.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TRI0779

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