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compositionComposition:CISPLATIN-10MG
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Prescription Medicine
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Tumotin 10mg Injection is used for the treatment of tumours of the ovary, testis, bladder, neck and head epithelial tumour, lung cancer, and cervical cancer. Tumotin 10mg Injection contains Cisplatin, which works by preventing the growth of cancer cells and eventually destroying them. Thereby, it helps treat cancer. In some cases, Tumotin 10mg Injection may cause side effects such as nausea, vomiting, tiredness, hair loss, pain or redness at the site of injection.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CISPLATIN-10MG

Manufacturer/Marketer :

Max India Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tumotin 10mg Injection

Tumotin 10mg Injection is an injectable prescription medicine used to treat advanced cancers of the bladder, ovaries, and testicles. It is a chemotherapy treatment that helps stop cancer cells from growing and multiplying in the body. Doctors typically prescribe it when these types of cancer have spread or have not responded well to other therapies.

This medicine is given as an injection directly into a vein, usually in treatment cycles that take place every three to four weeks. Because it is injected directly into your bloodstream, you do not need to worry about food affecting how well it is absorbed. However, staying highly hydrated before, during, and after your treatment is one of the most important steps you can take to help protect your body during therapy.

While this medicine is highly effective, it can cause common side effects like severe nausea, vomiting, and a temporary loss of appetite. It is important to watch for more serious symptoms, such as ringing in your ears or a sudden decrease in how much you urinate. If you notice any of these serious signs, you must contact your doctor right away.

Before you begin treatment, you should talk to your doctor if you have a history of kidney disease, hearing difficulties, or low blood cell counts. Do not take this medicine if you have severe kidney problems, pre-existing hearing loss, or severely weakened bone marrow activity.

This medication can interact with certain strong antibiotics and water pills, which can increase the risk of kidney and hearing damage. It is also important to talk to your doctor if you drink alcohol or smoke, as these habits can worsen nausea and dehydration. Pregnant or breastfeeding individuals must not receive this medicine, and elderly patients may require closer monitoring by their healthcare team.

Uses of Tumotin 10mg Injection

Tumotin 10mg Injection is used to treat advanced cancers of the bladder, ovaries, and testicles. The detailed uses of Tumotin 10mg Injection are as follows:

  • Testicular cancer: Helps treat advanced cancers of the testicles, often working alongside other medicines to stop cancer cells from multiplying.
  • Ovarian cancer: Helps manage advanced ovarian cancer that has spread, aiding in shrinking tumours and slowing down the progress of the disease.
  • Bladder cancer: Helps treat advanced bladder cancer when local treatments are no longer effective.

Key Benefits

Tumotin 10mg Injection helps treat certain types of cancer by slowing or stopping the growth of rapidly dividing cancer cells. With regular use as prescribed, it helps control disease progression, reduce tumour-related symptoms, and support better treatment outcomes.

  • Helps Control Cancer Growth: By interfering with the division of rapidly growing cancer cells, this medicine helps shrink tumours and slow the progression of the disease.
  • Relieves Cancer-Related Symptoms: As tumour growth is controlled, this medicine may help reduce pain, pressure, and discomfort caused by advanced cancers, improving daily comfort.
  • Supports Long-Term Disease Management: By helping prevent the spread of cancer to other parts of the body, this medicine supports ongoing cancer control, improves quality of life, and contributes to better overall treatment outcomes.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Tumotin 10mg Injection will be administered in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents.
  • Do not self-administer.

How Tumotin 10mg Injection Works

Tumotin 10mg Injection contains cisplatin, which is an anticancer medicine that targets the genetic material, or DNA, inside cancer cells. Once injected into the bloodstream, it travels throughout the body and enters the cancer cells. Inside these cells, it binds to the DNA, creating abnormal cross-links that damage the genetic structure. This structural damage prevents the cancer cells from copying their DNA and dividing. Because cancer cells grow and multiply much faster than normal healthy cells, they are highly sensitive to this action. When the cancer cells are unable to divide, they trigger a natural cell death process, which helps stop the tumour from growing.
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Alcohol

Consult your doctor

It is not known if alcohol affects Tumotin 10mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Cisplatin belongs to pregnancy category D. Tumotin 10mg Injection may cause foetal harm. Therefore, it should not be used during pregnancy.

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Breast Feeding

Unsafe

Cisplatin has been reported to be found in human milk. Breastfeeding is not recommended during treatment and for four weeks after the treatment with Tumotin 10mg Injection.

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Driving

Caution

Tumotin 10mg Injection may cause dizziness and tiredness. Avoid driving if you experience any side effects that might lessen your ability to do so.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Tumotin 10mg Injection.

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Kidney

Caution

Tumotin 10mg Injection should not be used if you have severe kidney disease or pre-existing renal impairment. If you have a history of kidney disease, inform your doctor before receiving Tumotin 10mg Injection.

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Children

Caution

Tumotin 10mg Injection is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Tumotin 10mg Injection should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Tumotin 10mg Injection.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Tumotin 10mg Injection to geriatric patients. Your doctor will prescribe Tumotin 10mg Injection if the benefits outweigh the risks.

What if I have taken an overdose of Tumotin 10mg Injection

Because healthcare professionals prepare and inject this medicine, an overdose is highly unlikely. However, if you suspect an error or experience severe, sudden symptoms after your infusion, tell your healthcare team or seek emergency medical attention right away.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Drink at least 8 to 12 cups of water or clear broths daily, especially in the days surrounding your treatment, to help flush your kidneys and protect them from damage.
  • Eat small, frequent meals: To manage nausea, try eating five or six small meals throughout the day instead of three large ones. Stick to dry, bland foods like toast, crackers, or rice.
  • Avoid infections: Wash your hands frequently, avoid crowds, and stay away from people who are sick, as this medicine can temporarily lower your white blood cell count.
  • Practice gentle mouth care: Use a soft-bristled toothbrush and rinse your mouth with water or a mild baking soda solution to help prevent painful mouth sores.
  • Protect your ears: Avoid very loud environments and wear ear protection when necessary, as your ears may be more sensitive to damage during therapy.
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How Soon It Starts Working

The time required for Tumotin 10mg Injection to start to work: The time required for Tumotin 10mg Injection to show its action is not clinically established. The time for which the effects of Tumotin 10mg Injection last: The duration of action for Tumotin 10mg Injection is not clinically established.

What if you forget to take Tumotin 10mg Injection

Since this medication is given on a strict clinical schedule, missing an appointment is rare. If you miss a scheduled infusion session, contact your doctor or clinic immediately to reschedule your treatment as soon as possible.

Storage

• In the clinic or hospital setting, Tumotin 10mg Injection is stored at a controlled room temperature between 15°C to 25°C (59°F to 77°F).

Drug Warnings

  • Check the solution before your infusion; it should be clear, colourless, and free of any visible floating particles.
  • Tell your nurse immediately if you feel any burning, stinging, coldness, or pain around the injection site while the medicine is being injected.
  • Keep all your scheduled appointments for blood tests and hearing checks, as your doctor needs these to monitor your kidneys, blood counts, and hearing.
  • Use reliable birth control during your treatment and for several months afterwards, as this medicine can cause severe harm to an unborn baby.
  • Do not get any live vaccines while receiving this medicine without talking to your doctor first.
     

Drug-Drug Interactions

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  • Strong antibiotics (like gentamicin): May increase the risk of severe kidney damage and hearing loss.
    Water pills (like furosemide): Can increase the risk of hearing damage when used at the same time as this medication.

Drug-Drug Interactions

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How does the drug interact with Tumotin 10mg Injection:
Using Tumotin 10mg Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Tumotin 10mg Injection and Ziprasidone together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tumotin 10mg Injection:
Taking Tofacitinib with Tumotin 10mg Injection may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Tumotin 10mg Injection, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tumotin 10mg Injection:
Combining Tumotin 10mg Injection with Clozapine can increase the risk of neutropenia (Infection).

How to manage the interaction:
Although there is a possible interaction between Tumotin 10mg Injection and Clozapine, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain during urination, contact your doctor immediately." Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tumotin 10mg Injection:
Taking tacrolimus with Tumotin 10mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Tumotin 10mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tumotin 10mg Injection:
Taking thalidomide together with Tumotin 10mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Tumotin 10mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tumotin 10mg Injection:
Coadministration of Tumotin 10mg Injection with amiodarone may increase the risk of abnormal cardiac rhythms and raises Amiodarone blood levels.

How to manage the interaction:
Although taking Tumotin 10mg Injection with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
How does the drug interact with Tumotin 10mg Injection:
The combined use of cladribine with Tumotin 10mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Tumotin 10mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tumotin 10mg Injection:
The combined use of Tumotin 10mg Injection and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Tumotin 10mg Injection and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tumotin 10mg Injection:
Combining Infliximab with Tumotin 10mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Tumotin 10mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tumotin 10mg Injection:
Coadministration of Tumotin 10mg Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Baricitinib and Tumotin 10mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No clinically significant food interactions are known with Tumotin 10mg Injection when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

You should consult your doctor before receiving any vaccines while being treated with Tumotin 10mg Injection. Live vaccines are generally avoided because this medicine may weaken your immune system and increase the risk of infection. Your doctor will advise which vaccines are safe and when they should be given.
Yes. Tumotin 10mg Injection can cause hearing problems, including ringing in the ears (tinnitus) and hearing loss, which may sometimes be permanent. Inform your doctor if you already have hearing problems before starting treatment. Your doctor may perform hearing tests before and during treatment and adjust therapy if necessary. Contact your doctor immediately if you notice changes in your hearing.
Yes. Hair thinning or hair loss is a common side effect of Tumotin 10mg Injection. It is usually temporary, and hair generally grows back after treatment ends. Be gentle when brushing and washing your hair, and speak with your healthcare team if you have concerns or would like advice on managing hair loss.
This medicine is given as a slow drip into a vein (an intravenous infusion) by a healthcare professional in a hospital or clinic. Talk to your doctor if you have questions about the infusion process.
Staying deeply hydrated helps flush the medicine through your kidneys, which is critical for protecting them from damage. Talk to your doctor about exactly how much water you should drink.
Tell your nurse or doctor immediately if you feel pain, burning, coldness, or swelling around the needle. Talk to your doctor or nurse right away if this occurs.
No, this medicine can harm an unborn baby and must not be used during pregnancy. Talk to your doctor about effective birth control options during your treatment.
It is typically given in treatment cycles, often once every 3 to 4 weeks, to allow your body time to rest and recover between sessions. Talk to your doctor about your specific treatment schedule.

Disclaimer

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Country of origin

India
Other Info - TU16428
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