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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Twelup OD Tablet is used to treat peripheral neuropathy and Megaloblastic anemia caused by vitamin B12 deficiency. This medicine contains mecobalamin, which helps protect the nerves from damage and promotes blood cell production. Some common side effects include nausea, vomiting, diarrhoea, and headache.

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Composition :

MECOBALAMIN-1500MCG

Manufacturer/Marketer :

Nexkem Pharmaceuticals Pvt Ltd

Consume Type :

SUBLINGUAL

Return Policy :

Not Returnable

Expires on or after :

About Twelup OD Tablet

Twelup OD Tablet belongs to the class of vitamins primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Megaloblastic anaemia is a condition in which the red blood cells are abnormally large. Peripheral neuropathy causes damage to the nerves located outside the spinal cord and brain.

Twelup OD Tablet contains Mecobalamin, a crucial B12 variant that replenishes low levels. Restored vitamin B12 levels help soothe nerve pain, support healthy cell function, and contribute to blood health and protein building.

Sometimes, Twelup OD Tablet may cause common side effects like nausea, vomiting, diarrhoea, loss of appetite, and headache. These side effects do not require medical attention and gradually resolve over time. If these side effects are persistent, please reach out to your doctor.

Do not take it if you are allergic to any component present in it; if you are unsure, check with your doctor. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding. Keep your doctor informed about your present and past medical history and ongoing medicines to rule out any side effects. Consumption of alcohol should be avoided: Excessive alcohol consumption can interfere with B12 absorption.

Uses of Twelup OD Tablet

Twelup OD Tablet is used to treat peripheral neuropathy and megaloblastic anemia caused by vitamin B12 deficiency. The detailed uses of Twelup OD Tablet are as follows:

  • Treats peripheral neuropathy:Twelup OD Tablet helps repair and protect nerves damaged due to vitamin B12 deficiency, reducing numbness, tingling, and weakness.
  • Treats megaloblastic anemia:Twelup OD Tablet corrects anemia caused by insufficient vitamin B12, improving red blood cell formation and oxygen delivery.

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Directions for Use

  • Twelup OD Tablet can be taken on an empty stomach for better absorption.
  • Follow your doctor’s instructions on the dosage and timing of this medication. It is often taken in the morning, at least 30 minutes before or two hours after a meal.
  • Place the tablet below the tongue and allow it to dissolve.
  • Do not break, chew, or crush it.
  • Do not handle the tablet with wet hands.

Medicinal Benefits

Twelup OD Tablet belongs to the class of vitamins primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Twelup OD Tablet contains Mecobalamin, a form of vitamin B12, which protects the nerves from damage and promotes blood cell production. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

How Twelup OD Tablet Works

Twelup OD Tablet contains Mecobalamin, a crucial B12 variant that replenishes low levels. Restored vitamin B12 levels help soothe nerve pain, support healthy cell function, and contribute to blood health and protein building.

Storage

• Store in a cool and dry place away from sunlight.• Keep Twelup OD Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Before taking the Twelup OD Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use Twelup OD Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. The prolonged use of larger doses of Twelup OD Tablet is not recommended for patients whose occupation requires the handling of mercury or mercury compounds.

Diet & Lifestyle Advise

Diet

Include B12-rich foods:

  • Animal-based products: Meat (especially liver), poultry, fish, eggs, milk, and dairy products.
  • Fortified foods: Some breakfast cereals, plant-based milk, and nutritional yeast.
  • Consider supplements: If dietary changes aren't sufficient, consult your doctor about B12 supplements. They can be oral, nasal, or injected.
  • Vegans and vegetarians: Pay close attention to B12 intake, as it's primarily found in animal products. Opt for fortified foods or supplements.

Lifestyle

  • Regular check-ups: If you're at risk (older adult, vegan/vegetarian, digestive issues), get regular B12 checks.
  • Limit alcohol: Excessive alcohol consumption can interfere with B12 absorption.
  • Healthy gut: Conditions like Crohn's disease or celiac disease can affect B12 absorption. Manage these conditions effectively.

Habit Forming

No

Therapeutic Class

VITAMINS
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Alcohol

Caution

Limit alcohol: Excessive alcohol consumption can interfere with B12 absorption.

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Pregnancy

Caution

Please visit your doctor. There are no competent and well-controlled pregnancy studies. Your doctor will only provide a prescription if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor; there has been no significant research on the use of Twelup OD Tablet in breastfeeding/nursing moms.

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Driving

Caution

It's unclear whether Twelup OD Tablet affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

Limited information was available about using Twelup OD Tablet in patients with liver disease. If you have a history of liver impairment, inform your doctor before receiving the Twelup OD Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available about using Twelup OD Tablet in patients with kidney disease. If you have a history of kidney impairment, inform your doctor before receiving the Twelup OD Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There was limited information about the usage of Twelup OD Tablet in paediatric patients. Please seek medical advice. Only if the benefits exceed the dangers will your doctor prescribe.

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Heart

Twelup OD Tablet is generally safe for people with heart problems and may even support heart health by lowering homocysteine levels. Still, it's best to consult your doctor before starting any supplement, especially if you're on cardiac medications.

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Geriatrics

Safe if prescribed

Geriatric patients can safely take Twelup OD Tablet . However, it's best to consult your doctor to confirm the right dose and rule out any interactions with other medications.

FAQs

Twelup OD Tablet belongs to the class of vitamins primarily used to treat peripheral neuropathies (nerve damage in the hands and feet) and megaloblastic anaemia (a blood disorder in which the red blood cells are abnormally larger than normal) caused by vitamin B12 deficiency.

Twelup OD Tablet addresses B12 insufficiency by replacing the body's low levels of vitamin B12. It further benefits in treating peripheral neuropathic pain by preventing nerve cell damage. It also involves cell proliferation, blood production, and protein synthesis.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Inform your doctor about all your medications, especially if you are taking chloramphenicol, colchicine, oral diabetes medicine (metformin), and drugs that reduce stomach acid such as cimetidine lansoprazole, omeprazole and antibiotic medications. These medications may interfere with Twelup OD Tablet and cause unpleasant side effects or might make Twelup OD Tablet less effective.

Vitamin B12 sources include eggs, beef, liver, chicken, trout, salmon, tuna, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese.

Country of origin

India

Manufacturer/Marketer address

Plot No. 288, 1st Floor, Industrial Area Phase 2, Panchkula, Haryana 134113
Other Info - TWE0012

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