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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Aprica Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Twinblok M 50mg Tablet

Twinblok M 50mg Tablet is an oral prescription medicine used to treat high blood pressure (hypertension). By keeping your blood pressure within a healthy range, it helps lower the risk of serious cardiovascular events such as strokes and heart attacks. This combination treatment is highly effective for patients whose blood pressure is not fully controlled by a single medication alone.

To get the best results, you must take Twinblok M 50mg Tablet consistently at the same time every day as directed by your doctor. You can take this tablet with or without food, though it is best to establish a consistent daily routine. Making healthy lifestyle choices, such as eating a low-salt diet and staying physically active, will significantly support the performance of this medication.

While taking Twinblok M 50mg Tablet , some people may experience mild side effects, including dizziness, ankle swelling, or a slower heart rate. However, you should contact your doctor immediately if you experience serious side effects like extreme lightheadedness, fainting, shortness of breath, or sudden chest pain.

Before you begin taking this medicine, talk to your doctor if you have a history of asthma, severe heart failure, liver damage, or kidney problems. Do not take this if you have a very slow heart rate, severe heart block, or extremely low blood pressure.

Avoid drinking alcohol while taking this medicine, as it can excessively lower your blood pressure and increase drowsiness. Smoking should also be avoided because it can make this medication less effective at protecting your heart. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this medicine is safe for your specific situation.

Uses of Twinblok M 50mg Tablet

Twinblok M 50mg Tablet is used to treat high blood pressure (hypertension). The detailed uses of Twinblok M 50mg Tablet are as follows:

  • High blood pressure (Hypertension): Twinblok M 50mg Tablet relaxes the blood vessels and slows down your heart rate, which safely lowers elevated blood pressure.
  • Prevention of heart attacks and strokes: By keeping your blood pressure under control over the long term, this medicine reduces the workload on your heart and lowers the risk of life-threatening cardiovascular complications.
  • Angina (heart-related chest pain): In some patients, and where clinically appropriate, the active components may help improve blood flow and reduce the heart's oxygen demand, which can help prevent chest discomfort during physical activity. This is generally a physician-directed use and may not be a primary approved indication in all markets.

 

Key Benefits

Twinblok M 50mg Tablet helps manage high blood pressure by combining two complementary medicines that work together to improve blood flow and reduce the strain on your heart. This dual-action approach provides effective blood pressure control while simplifying treatment with a single daily tablet.

  • Helps Maintain Healthy Blood Pressure: By lowering and stabilising blood pressure levels, Twinblok M 50mg Tablet reduces the workload on the heart and helps protect blood vessels from damage caused by uncontrolled hypertension.
  • Supports Long-Term Heart and Blood Vessel Health: Consistent blood pressure control can help lower the risk of serious cardiovascular complications such as heart attack, stroke, and kidney damage, supporting better long-term health outcomes.
  • Simplifies Daily Treatment: Combining two medicines into one tablet makes treatment more convenient, helping improve adherence to therapy and making it easier to manage your condition every day.
     
Side effects of Twinblok M 50mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

To ensure safe and effective treatment, follow these guidelines when taking this medication:

  • Swallow the tablet whole with a glass of water. Do not chew, crush, or break it, as this can release the medicine too quickly and increase your risk of side effects.
  • Take your dose at the same time every day to maintain a steady level of the medicine in your body.
  • You can take this medicine with or without food, but be consistent with your choice from day to day.
  • Always follow your doctor's exact instructions regarding your dose and how often to take it. Do not change your dose or stop taking this medicine suddenly without consulting your healthcare provider.
     

How Twinblok M 50mg Tablet Works

Twinblok M 50mg Tablet works through the combined action of two distinct active ingredients: a calcium channel blocker called cilnidipine and a beta-blocker called metoprolol. Cilnidipine works by blocking both L-type and N-type calcium channels. The L-type calcium channel blockade relaxes and widens blood vessels, allowing blood to flow more smoothly with less resistance. The additional N-type calcium channel blockade helps reduce excessive sympathetic nerve activity, which is one reason cilnidipine is less likely to cause reflex tachycardia (a sudden increase in heart rate) compared with some other calcium channel blockers. Metoprolol targets the heart muscle directly. It blocks the action of certain chemical messengers, such as adrenaline, which naturally slows down your heart rate and reduces how hard your heart has to pump. Together, these two mechanisms lower your blood pressure, decrease your heart's oxygen demand, and protect your cardiovascular system from strain.
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Alcohol

Unsafe

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with Twinblok M 50mg Tablet .

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Pregnancy

Consult your doctor

Twinblok M 50mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Small amounts of Twinblok M 50mg Tablet pass into the breast milk. However, which is not enough to cause any problems for your baby. But still, it is advisable to contact your doctor before breastfeeding your baby.

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Driving

Unsafe

Twinblok M 50mg Tablet may cause side effects which could affect your ability to drive. Taking Twinblok M 50mg Tablet may lower your blood pressure.

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Liver

Caution

Twinblok M 50mg Tablet to be taken with caution, especially if you have a history of liver disease. Please consult the doctor, and your doctor may adjust the dose.

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Kidney

Caution

Twinblok M 50mg Tablet to be taken with caution, especially if you have a history of kidney disease like increased creatinine level. Your doctor can adjust the dose.

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Children

Unsafe

The safety and effectiveness of Twinblok M 50mg Tablet have not been established in children due to limited testing of this drug on children.

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Heart

Safe if prescribed

Twinblok M 50mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Twinblok M 50mg Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Twinblok M 50mg Tablet

Do not take more than the prescribed dose of Twinblok M 50mg Tablet as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce sodium (salt) intake: High sodium levels cause your body to hold onto water, which raises your blood pressure. Limit processed foods and season your meals with herbs and spices instead of salt.
  • Avoid grapefruit products: Grapefruit and grapefruit juice can interact with cilnidipine, raising the drug levels in your blood and increasing the risk of side effects like severe dizziness and swelling.
  • Monitor your pulse: Since this medicine slows your heart rate, check your pulse regularly. If your resting heart rate drops below 50 beats per minute, talk to your doctor.
  • Rise slowly: To prevent sudden dizziness or lightheadedness when moving from a sitting or lying position, stand up slowly and hold onto a stable surface if needed.
  • Stay active safely: Engage in regular, moderate aerobic exercises like brisk walking or swimming, but always consult your doctor before starting any new exercise routine.
     

Have a query?

How Soon It Starts Working

  • The time required for Twinblok M 50mg Tablet to start to work: Twinblok M 50mg Tablet ideally shows its action within 1 hour after administration.
  • The time for which the effects of Twinblok M 50mg Tablet last: The duration of action for Twinblok M 50mg Tablet is unknown.

What if you forget to take Twinblok M 50mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Twinblok M 50mg Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister pack or container to protect them from moisture and direct light.

Drug Warnings

  • Do not stop taking this medicine suddenly: Stopping metoprolol abruptly can cause a dangerous rebound increase in blood pressure, severe chest pain, or even a heart attack. Your doctor will guide you through gradually decreasing dose if you need to stop.
  • Inform all healthcare providers: Let your dentist, surgeon, or anaesthesiologist know you are taking Twinblok M 50mg Tablet before undergoing any medical or dental procedure, as it can interact with certain anaesthetics.
  • Check your blood pressure at home: Keep a regular written log of your blood pressure readings to share with your doctor during your routine check-ups.
  • Avoid hazardous activities initially: This medicine can cause dizziness or drowsiness, especially during the first few days. Avoid driving or operating machinery until you know exactly how it affects you.
  • Watch for signs of fluid buildup: If you experience sudden weight gain, increased ankle swelling, or find it difficult to breathe when lying flat, contact your doctor right away, as these can be signs of worsening heart failure.

 

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

  • Other blood pressure medications: Combining this medicine with other drugs that lower blood pressure can cause your blood pressure to drop too low.
  • Heart rhythm medications (such as amiodarone or digoxin): Can lead to a dangerously slow heart rate when taken with metoprolol.
  • Pain relievers (NSAIDs like ibuprofen): May reduce the blood pressure-lowering effectiveness of this medicine.

Drug-Food Interactions

  • Grapefruit juice: Can increase the concentration of cilnidipine in your blood, raising the risk of severe side effects.
  • Alcohol: May excessively lower your blood pressure, leading to extreme dizziness, fainting, or drowsiness.

Drug-Disease Interactions

  • Asthma or COPD: The metoprolol component can narrow your airways, making breathing difficult for patients with chronic lung diseases.
  • Diabetes: This medication may mask the physical warning signs of low blood sugar, such as a fast heart rate or shaking.
  • Severe liver damage: Your body may process this medication much more slowly, which can increase the drug's effects and risk of toxicity.
     
Severe

Drug-Drug Interactions

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How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Twinblok M 50mg Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with Acebutolol may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Twinblok M 50mg Tablet can be taken with Acebutolol if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with Diltiazem can increase the toxicity of either of the medications.

How to manage the interaction:
Although there is a possible interaction between Twinblok M 50mg Tablet and Diltiazem, you can take these medicines together if prescribed by a doctor. However, if you experience chest pain, confusion or memory problems, dizziness or lightheadedness, easily tiring during physical activity, fatigue, fainting, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Twinblok M 50mg Tablet:
Coadministration of Twinblok M 50mg Tablet together with Aminophylline can increase the effects of aminophylline, leading to risk and severity of side effects.

How to manage the interaction:
Taking Twinblok M 50mg Tablet with Aminophylline may lead to an interaction, it can be taken only if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with clonidine can increase the toxicity of either of the medications.

How to manage the interaction:
Although there is a possible interaction between Twinblok M 50mg Tablet and clonidine, you can take these medicines together if prescribed by a doctor. However, if you experience chest pain, confusion or memory problems, dizziness or lightheadedness, easily tiring during physical activity, fatigue, fainting, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Twinblok M 50mg Tablet:
Using Twinblok M 50mg Tablet with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Twinblok M 50mg Tablet and Saquinavir, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Twinblok M 50mg Tablet:
Coadministration of Twinblok M 50mg Tablet together with Artemether can increase the level or effect of metoprolol.

How to manage the interaction:
Taking Twinblok M 50mg Tablet with Artemether may lead to an interaction, it can be taken only if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Twinblok M 50mg Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult a doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Twinblok M 50mg Tablet:
Co-administration of Twinblok M 50mg Tablet with Disopyramide can lead to major heart-related complications like abnormally low blood pressure, fainting, irregular heart rhythm and abnormally slow heart rate.

How to manage the interaction:
Although there may be an interaction, Twinblok M 50mg Tablet can be taken with Disopyramide if prescribed by a doctor. Consult a doctor if you experience any symptoms such as dizziness, palpitations, fainting, shortness of breath, or heart palpitations . Do not discontinue any medication without a doctor's advice.
How does the drug interact with Twinblok M 50mg Tablet:
Taking Twinblok M 50mg Tablet together with Ceritinib can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Twinblok M 50mg Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Twinblok M 50mg Tablet is used to treat high blood pressure (hypertension). By lowering blood pressure, it also helps to prevent heart attack.

Twinblok M 50mg Tablet contains Metoprolol and Cilnidipine. Metoprolol helps to relax our blood vessels by preventing the function of certain natural compounds in our bodies. It helps to slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Cilnidipine is a calcium channel blocker that inhibits the activity of calcium channels in blood vessels in the heart. As a result, the blood arteries dilate, and the heart's supply rises, lowering the high blood pressure and the heart's workload. Both help to lower blood pressure and the likelihood of having a heart attack or stroke in the future.

Usually, Twinblok M 50mg Tablet is prescribed for a long term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Yes, Twinblok M 50mg Tablet can cause a sudden drop in blood pressure, especially when you start taking Twinblok M 50mg Tablet , to avoid a sudden drop, please get up gently when sitting down to avoid dizziness.

No, you must not stop taking Twinblok M 50mg Tablet unless your doctor specifically instructs you to do so. Even if your blood pressure becomes normal, it may rise again if treatment is stopped. High blood pressure often has no symptoms, and suddenly discontinuing Twinblok M 50mg Tablet may cause a dangerous increase in blood pressure or worsen heart-related problems. If you have any concerns or experience discomfort, consult your doctor before making any changes to your treatment

High blood pressure in the pregnancy stage may cause eclampsia that can be harmful to both babies and mothers. So, during the pregnancy, you should have regular blood pressure monitoring and doctor consultations.

Twinblok M 50mg Tablet can be taken on an empty stomach or with food. Take it with food if you experience stomach upset.

Twinblok M 50mg Tablet may cause side effects like dizziness, peripheral oedema (swelling of legs/hands), cold hands or feet, difficulty sleeping and nightmares. Consult the doctor if the side effects persist or worsen.

It is highly recommended to avoid alcohol while taking this medicine. Alcohol can interact with Twinblok M 50mg Tablet , causing a sudden drop in blood pressure and increasing side effects like drowsiness, headache, and severe dizziness. Talk to your doctor for more advice.

Cilnidipine, one of the active ingredients, works by widening your blood vessels. This relaxation of the blood vessels can sometimes lead to mild fluid accumulation in your lower legs and ankles. If the swelling becomes painful or worsens, talk to your doctor.

Yes, feeling tired, sluggish, or sleepy is a common side effect, primarily because the metoprolol component slows down your heart rate and lowers your blood pressure. If this fatigue interferes with your daily activities, talk to your doctor.

Twinblok M 50mg Tablet does not directly change your blood sugar, but it can mask the warning signs of low blood sugar (hypoglycaemia), such as a rapid heart rate or palpitations. If you have diabetes, monitor your blood sugar closely and talk to your doctor.

While a slower heart rate is expected with metoprolol, a pulse rate below 50 beats per minute requires medical attention. If you also feel weak, dizzy, or short of breath, contact your doctor right away.

This medicine is generally not recommended during pregnancy or breastfeeding, as it may cause harm to the developing baby. If you are pregnant, planning to conceive, or nursing, talk to your doctor to discuss safer alternatives.

You should avoid taking pain relievers like ibuprofen or naproxen regularly without medical advice. These medications can reduce the blood pressure-lowering effects of Twinblok M 50mg Tablet and may affect your kidney function. Talk to your doctor or pharmacist for safe pain relief options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

A/4 4Th Floor, Safal Profitaire,Corporate Road,Nr Prahladnagar Garden, Prahladnagar,Ahmedabad- 380015, Gujarat, India.
Other Info - TWI0089
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