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compositionComposition:CHOLECALCIFEROL-600000IU
prescription
Prescription Medicine
info
Uprise D3 Injection 6*1ml
Uprise D3 Injection 6*1ml
Uprise D3 Injection 6*1ml

Uprise D3 Injection 6*1ml is used to regulate calcium and phosphate metabolism. It effectively treats various conditions in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). It contains Vitamin-D3 (Cholecalciferol), a fat-soluble vitamin. It helps maintain blood calcium and phosphorus levels and the mineralization of bone. It treats and prevents bone disorders, such as rickets and osteomalacia. It aids in calcium absorption, enabling bone growth and repair. It further prevents cartilage degeneration. It is also used to maintain a healthy immune system.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHOLECALCIFEROL-600000IU

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Uprise D3 Injection 6*1ml

Uprise D3 Injection 6*1ml is a vitamin supplement primarily used to treat vitamin D deficiency. Vitamin D deficiency occurs when your body has low Vitamin D levels and is caused by inadequate nutrition, intestinal malabsorption, or lack of sunlight exposure. It effectively treats various conditions, including low calcium levels, osteoporosis (weak bones), latent tetany (a muscle disease characterized by low blood calcium levels), and rickets or osteomalacia (softening of bones due to low calcium levels).

Uprise D3 Injection 6*1ml contains Cholecalciferol, a form of vitamin D. It promotes the absorption of calcium, phosphorus, and vitamin A from different organs and helps maintain overall health.

Uprise D3 Injection 6*1ml is safe to use in children when recommended by the paediatrician. Uprise D3 Injection 6*1ml is likely safe to consume. In rare cases, it may cause side effects such as constipation, increased blood calcium levels, elevated calcium levels in urine, vomiting, and nausea. These side effects typically do not require medical attention and usually resolve gradually over time. If these side effects persist, please consult your physician immediately.

Inform your physician if you are allergic to Uprise D3 Injection 6*1ml. This medicine may contain sugar or aspartame. Hence, caution should be taken in diabetes and phenylketonuria (increased levels of an amino acid called phenylalanine). Let your doctor know if you have any liver/kidney disease, heart disease, kidney stones and hypervitaminosis D (having too much vitamin D) or are pregnant or breastfeeding before taking Uprise D3 Injection 6*1ml.

Uses of Uprise D3 Injection 6*1ml

Uprise D3 Injection 6*1ml is used in the treatment of vitamin D deficiency, osteomalacia (Rickets), osteoporosis, and hypocalcemia (low blood calcium levels). The detailed uses of Uprise D3 Injection 6*1ml are as follows:

  • Supports Calcium Absorption: Uprise D3 Injection 6*1ml helps the body absorb calcium, essential for strong bones.
  • Treats Vitamin D Deficiency: Uprise D3 Injection 6*1ml used when diet and sunlight exposure are insufficient.
  • Manages Osteoporosis: Uprise D3 Injection 6*1ml helps prevent bone thinning and fractures.
  • Boosts Immune Function: Uprise D3 Injection 6*1ml strengthens the immune system and overall health.

Key Benefits

  • Uprise D3 Injection 6*1ml is used to treat low blood calcium levels. It effectively treats various conditions in the body like Vitamin D deficiency, osteoporosis, hypoparathyroidism, latent tetany and rickets or osteomalacia.
  • Uprise D3 Injection 6*1ml contains cholecalciferol (vitamin D3). Cholecalciferol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources.
  • Uprise D3 Injection 6*1ml is a provitamin that is converted into a vitamin after intake. It helps maintain blood calcium and phosphorus levels and mineralisation of bone.
  • Uprise D3 Injection 6*1ml is also used in treating familial hypophosphatemia (a group of rare inherited disorders characterised by low phosphate levels resulting in deformities of the bones and teeth).

Directions for Use

  • The timing and frequency of Uprise D3 Injection 6*1ml will be determined by your doctor, based on your medical condition.
  • This medication should only be administered by a qualified healthcare provider.
  • Do not attempt self-administration of the injection.
  • Follow your healthcare provider’s instructions about the medication and any steps to track your progress or precautions during treatment.

How Uprise D3 Injection 6*1ml Works

Uprise D3 Injection 6*1ml contains Vitamin-D3 (Cholecalciferol), a fat-soluble vitamin. It helps maintain blood calcium and phosphorus levels and the mineralization of bone. It is used to treat and prevent bone disorders, such as rickets and osteomalacia. It aids in calcium absorption enabling bone growth and repair. It further prevents cartilage degeneration. Uprise D3 Injection 6*1ml is also used to maintain a healthy immune system.
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Alcohol

Caution

It is advised to avoid alcohol consumption while on treatment with Uprise D3 Injection 6*1ml to prevent any undesirable side effects.

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Pregnancy

Safe if prescribed

Uprise D3 Injection 6*1ml is considered safe to be used in pregnancy. However, let your doctor know if you are pregnant or planning pregnancy before taking Uprise D3 Injection 6*1ml. Your doctor will decide on the dose of this medicine based on your requirement.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor. Your doctor will decide the dose of Uprise D3 Injection 6*1ml based on your condition.

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Driving

Caution

Uprise D3 Injection 6*1ml usually does not interfere with your driving ability. Do not drive or operate machinery if you experience any dizziness while using Uprise D3 Injection 6*1ml. Please consult your doctor if you notice any symptoms.

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Liver

Consult your doctor

Inform your doctor if you have any pre-existing or history of liver diseases before receiving Uprise D3 Injection 6*1ml.

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Kidney

Consult your doctor

Inform your doctor if you have kidney diseases like kidney stones or undergoing dialysis before receiving Uprise D3 Injection 6*1ml.

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Children

Consult your doctor

Please consult your doctor. Your doctor will decide the appropriate dose based on your child's condition.

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Heart

Consult your doctor

Inform your doctor if you have any pre-existing or history of heart diseases before receiving Uprise D3 Injection 6*1ml.

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Geriatrics

Consult your doctor

Please consult your doctor before giving Uprise D3 Injection 6*1ml to elderly people.

What if I have taken an overdose of Uprise D3 Injection 6*1ml

As Uprise D3 Injection 6*1ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Uprise D3 Injection 6*1ml may cause anorexia, arrhythmias, constipation, calcification of soft tissues, changes in ECG measurements, diarrhoea, fatigue, headache, kidney failure, muscle weakness, muscle and joint pain, nausea, nephrocalcinosis, polydipsia, polyuria formation of renal calculi, pancreatitis, and vomiting.

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy, spinach and other green leafy vegetables.
  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Have a query?

How Soon It Starts Working

The time required for Uprise D3 Injection 6*1ml to start to work: Uprise D3 Injection 6*1ml effect shows its action within 24 hours of administration. 

The time for which the effects of Uprise D3 Injection 6*1ml last: Uprise D3 Injection 6*1ml effect lasts for a few hours.

What if you forget to take Uprise D3 Injection 6*1ml

If you miss a dose, contact your healthcare provider to reschedule your next dose as needed.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Let your doctor know if you are allergic to Uprise D3 Injection 6*1ml or its inactive components.
  • Brief your medical history to the doctor in advance if you have any heart/kidney/liver diseases, electrolyte imbalance, alcoholism, or sarcoidosis before starting Uprise D3 Injection 6*1ml.
  • Please consult your doctor if you are pregnant, planning to conceive or are a breastfeeding mother before starting Uprise D3 Injection 6*1ml.
  • This supplement is safe to use in children when prescribed by the doctor depending on the child's age and body weight.
  • Inform your doctor if you have any history of hypercalcemia, hyperparathyroidism, kidney disease, liver disease, electrolyte imbalance, heart disease, kidney stones and hypervitaminosis D (having too much vitamin D) before taking Uprise D3 Injection 6*1ml.
  • Do not store Uprise D3 Injection 6*1ml above 25°C.

Drug-Drug Interactions

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Drug-Drug Interaction: Uprise D3 Injection 6*1ml may interact with fits medicines (phenytoin), heart-related drugs, water pills, and antacids (magnesium oxide).

Drug-Food Interaction: Limit alcohol intake during the course to get the maximum benefits of Uprise D3 Injection 6*1ml. 

Drug-Disease Interaction: Uprise D3 Injection 6*1ml is not recommended if you have hypercalcaemia (high calcium levels), hypervitaminosis, kidney stones, and calcification.

ColecalciferolCalcitriol
Severe
ColecalciferolDihydrotachysterol
Severe

Drug-Drug Interactions

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ColecalciferolCalcitriol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
The combined use of aluminum hydroxide with Uprise D3 Injection 6*1ml may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Uprise D3 Injection 6*1ml with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ColecalciferolCalcifediol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolSucralfate
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ColecalciferolErgocalciferol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDoxercalciferol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Uprise D3 Injection 6*1ml:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Uprise D3 Injection 6*1ml and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Uprise D3 Injection 6*1ml is used to treat Vitamin D deficiency, Osteomalacia (Rickets), Osteoporosis, and Hypocalcemia (low blood calcium levels).
Uprise D3 Injection 6*1ml is a dietary supplement that consists of Cholecalciferol or Vitamin D3. It regulates calcium and phosphate metabolism and works by increasing the amount of vitamin D in the body.
Uprise D3 Injection 6*1ml is used to increase low levels of calcium in the body. Hence it is not advised to use Uprise D3 Injection 6*1ml during hypercalcaemia since it causes an overdose of calcium leading to kidney stones and other effects.
Avoid taking more than one multivitamin product concomitantly unless advised by the doctor. Taking similar nutritional supplements simultaneously can lead to a vitamin overdose or other serious side effects.
Uprise D3 Injection 6*1ml may increase the absorption of Aluminium in antacids. Hence it is advised to take Uprise D3 Injection 6*1ml two hours before or four hours after taking antacids.
Fatty fish (tuna, trout, salmon, and mackerel), fish liver oil, egg yolk, and beef liver are good sources of Vitamin D. Vitamin D-fortified foods like plant milk, dairy, juices, and breakfast cereals are also good sources of Vitamin D.
Not getting enough vitamin D through diet/food, limited exposure to sunlight, organs such as the liver or kidney not being able to convert vitamin D to its active form in the body, taking medicines which interfere with the absorption of vitamin D may cause deficiency of vitamin D.
Uprise D3 Injection 6*1ml is administered either intramuscularly or subcutaneously by a healthcare professional.
Uprise D3 Injection 6*1ml helps treat and prevent bone disorders, supports immune health, and promotes muscle and nerve functioning. It aids the absorption of calcium and makes the bones strong.
Since a doctor will administer Uprise D3 Injection 6*1ml, he/she will determine the time of administration.
People who are allergic to vitamin D, have hypervitaminosis D (high levels of vitamin D), hypercalcemia (high levels of calcium) or malabsorption syndrome should not take Uprise D3 Injection 6*1ml.
Too much vitamin D may cause hypervitaminosis D (high levels of vitamin D). However, as Uprise D3 Injection 6*1ml is administered by a doctor it is unlikely to overdose on this medicine.
The amount of Vitamin D3 needed depends on age. The average daily recommended amount as per NIH is Birth-12 months: 400IU 1-13 years: 600IU 14-18 years: 600IU 19-70 years: 600IU 71 years and older: 800IU Pregnant and breastfeeding women: 600IU
Vitamin D deficiency may cause rickets (bones become soft, weak and deformed) in children and osteomalacia (a bone disorder that causes muscle weakness and bone pain) in adults.

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Reference

  1. Drugs.com Clinical Review Team. Vitamin D3 Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Nair, Rathish, and Arun Maseeh. Vitamin D: The "sunshine" vitamin. National library of Medicine, National center for Biotechnology information. Pubmed Central. 2012 [Accessed on 21st June 2022] Check here
  5. Labialfarma. Electronics Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 21st June 2022] Check here
  6. Pil D3 Vicotrat En 2018 04. [Accessed on 02 Jun. 2026] Check here
  7. Pharma Patent Kft. Health Products Regulatory Authority (HPRA) [Revised in December 2020] [Accessed on 21st June 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - UPR0011

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