Ustekirel 45 mg Solution For Injection 0.5 ml

Your doctor may prescribe Ustekirel 45 mg Solution For Injection 0.5 ml to help manage the following conditions:

• Plaque psoriasis: Used to treat moderate to severe plaque psoriasis in people who need systemic treatment or phototherapy. It helps control the inflammation responsible for the characteristic skin plaques.
• Psoriatic arthritis: Used to treat active psoriatic arthritis, either alone or with methotrexate. It helps control inflammation affecting the joints and may also improve associated psoriasis.
• Crohn's disease: Used to treat moderate to severe active Crohn's disease. It reduces inflammation in the digestive tract and can help induce and maintain remission.
• Ulcerative colitis: Used to treat moderate to severe active ulcerative colitis. It reduces inflammation in the colon and can help induce and maintain remission.

When used as directed as part of your treatment plan, Ustekirel 45 mg Solution For Injection 0.5 ml may provide the following benefits:

• Improves skin symptoms: In plaque psoriasis, Ustekirel 45 mg Solution For Injection 0.5 ml can reduce the redness, scaling, thickness, and itching of plaques, improving skin comfort and making symptoms easier to manage.
• Improves joint symptoms and movement: In psoriatic arthritis, reducing inflammation can ease joint pain, swelling, and stiffness, helping you move more comfortably and carry out daily activities.
• Helps control bowel symptoms: In Crohn's disease and ulcerative colitis, reducing inflammation can improve symptoms such as diarrhoea, abdominal pain, rectal bleeding, and bowel urgency, depending on the condition.
• Supports longer-term symptom control: In people who respond to treatment, maintenance therapy can help sustain improvement and maintain remission in Crohn's disease or ulcerative colitis.

• Follow your doctor’s recommendations for the correct dosage and timing of this medication.
• Ustekirel 45 mg Solution For Injection 0.5 ml comes in a prefilled syringe to be given by a healthcare professional; if you are well-trained and advised by your doctor to administer Ustekirel 45 mg Solution For Injection 0.5 ml at home, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
• Choose an injection site such as the thigh, upper arm, or abdomen; pinch the skin and inject the advised dose slowly and steadily, then remove the needle.
• Rotate the injection site each time. Do not inject into skin that is red, bruised, or hard.
• Wash your hands before and after administration.
• Do not use Ustekirel 45 mg Solution For Injection 0.5 ml if it is frozen or if the liquid is cloudy or contains small particles.

• Track your food: If you are treating Crohn's or ulcerative colitis, keep a daily food journal to identify and avoid personal trigger foods that can worsen inflammation.
• Eat anti-inflammatory foods: Focus on a balanced diet rich in leafy greens, berries, and healthy fats like olive oil and wild-caught fish, which naturally help manage systemic inflammation.
• Choose low-impact exercises: For joint pain from psoriatic arthritis, engage in gentle activities like swimming, stationary cycling, or yoga to keep your joints flexible without causing strain.
• Moisturise your skin regularly: If you have psoriasis, apply thick, fragrance-free moisturisers immediately after bathing to lock in moisture and protect your skin barrier.
• Avoid smoking: Smoking can significantly reduce the effectiveness of your treatment and is a known trigger for both psoriasis flares and severe bowel inflammation.

• Inspect before injecting: Check the appearance of the solution every single time; it must be clear or slightly pearly, and never cloudy or discoloured.
• Rotate your injection sites: Inject in a different spot each time (thigh, abdomen, or outer upper arm) to prevent skin irritation or thickening.
• Avoid damaged skin: Never inject into skin areas that are bruised, tender, red, hard, or actively affected by psoriasis plaques.
• Watch out for live vaccines: Do not receive any live vaccines while using this medicine, as your body's immune defence is lowered.
• Complete a tuberculosis check: Ensure your doctor tests you for tuberculosis (TB) before you begin treatment, as latent TB can reactivate during therapy.