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compositionComposition:PROGESTERONE-300MG
prescription
Prescription Medicine
info
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Vageston 300 mg Capsule is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

PROGESTERONE-300MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vageston 300 mg Capsule

Vageston 300 mg Capsule is an oral prescription medication used to treat absent menstrual periods and to prevent overgrowth of the uterine lining in women undergoing estrogen hormone replacement therapy. It helps restore hormonal balance in the body, ensuring a regular menstrual cycle and protecting uterine health.

For the best results, you must take Vageston 300 mg Capsule exactly as prescribed by your doctor. Some oral Vageston 300 mg Capsule formulations are recommended on an empty stomach, while others may be taken with food. Follow the instructions provided with your specific product and use the same method consistently each day, as food can affect how much medicine your body absorbs.

While taking Vageston 300 mg Capsule , you may experience mild side effects such as drowsiness, dizziness, or mild stomach upset. However, if you experience severe symptoms like chest pain, sudden severe headaches, or breathing difficulties, you must seek immediate medical attention.

Do not take this if you have a history of blood clots, breast cancer, unusual vaginal bleeding, or severe liver damage. Before starting, tell your doctor if you have high blood pressure, asthma, diabetes, or migraine headaches so they can monitor your health closely.

Vageston 300 mg Capsule can interact with certain medicines that speed up how your liver breaks down drugs (called liver enzyme-inducing medicines), such as carbamazepine or phenytoin. These medicines may reduce how well Vageston 300 mg Capsule works. Alcohol and smoking may also increase the risk of side effects or affect treatment. If you are pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider to discuss the specific risks and benefits of using this medication.

Uses of Vageston 300 mg Capsule

Vageston 300 mg Capsule is used in the treatment of female infertility, female hormonal imbalance, secondary amenorrhea, and hormone replacement therapy. The detailed uses of Vageston 300 mg Capsule are as follows:

  • Hormone Replacement Therapy (HRT): Helps prevent the overgrowth of the uterine lining in postmenopausal women who are taking estrogen.
  • Secondary Amenorrhea: Helps restore normal menstrual periods in women who have stopped having periods due to a lack of natural progesterone.
  • Luteal Phase Support: Vageston 300 mg Capsule may be prescribed after fertility treatments or in selected women to help prepare and maintain the uterine lining during early pregnancy when recommended by a fertility specialist.
  • Female Hormonal Imbalance: Helps restore normal progesterone levels, supporting a healthy menstrual cycle and proper reproductive function.
     

Key Benefits

Vageston 300 mg Capsule helps support hormonal balance and reproductive health by replacing or supplementing the body's natural Vageston 300 mg Capsule . It plays an important role in regulating the menstrual cycle, supporting pregnancy, and protecting the uterus during hormone therapy.

Benefits may include:

  • Helps regulate menstrual cycles and supports normal reproductive hormone balance.
  • Supports the maintenance of early pregnancy when prescribed for Vageston 300 mg Capsule deficiency.
  • Helps protect the lining of the uterus during estrogen replacement therapy in postmenopausal women.
  • Supports the management of irregular periods and certain hormone-related conditions.
  • Helps reduce the risk of uterine complications associated with estrogen-only hormone therapy.
  • Promotes overall reproductive health and improves quality of life when used as prescribed.
     
Side effects of Vageston 300 mg Capsule
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.

Directions for Use

  • Vageston 300 mg Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Vageston 300 mg Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Vageston 300 mg Capsule Works

Vageston 300 mg Capsule replaces the natural hormone that your body may not be producing in sufficient amounts. After you swallow the capsule, it is processed by the liver before reaching the bloodstream, so the dose and schedule may vary between individuals. Your doctor will prescribe the amount that is most appropriate for your condition.
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Alcohol

Consult your doctor

Interaction of Vageston 300 mg Capsule with alcohol is unknown. Please consult a doctor before consuming alcohol while using Vageston 300 mg Capsule .

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Pregnancy

Consult your doctor

Vageston 300 mg Capsule supports pregnancy and helps in the maintenance of pregnancy. However, please consult a doctor if you are pregnant before taking Vageston 300 mg Capsule .

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Breast Feeding

Consult your doctor

Vageston 300 mg Capsule may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Vageston 300 mg Capsule may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking Vageston 300 mg Capsule .

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Liver

Consult your doctor

Please consult a doctor if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Vageston 300 mg Capsule should be given with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Vageston 300 mg Capsule is not recommended for children.

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Heart

Consult your doctor

Please consult your doctor if you have heart problems before using Vageston 300 mg Capsule .

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Vageston 300 mg Capsule in elderly patients.

What if I have taken an overdose of Vageston 300 mg Capsule

If you take more than your prescribed dose, seek emergency medical attention or contact a poison control center immediately. Symptoms of overdose may include severe dizziness, nausea, or drowsiness.

Diet & Lifestyle Advise

  • Ensure adequate calcium and vitamin D intake: Include calcium- and vitamin D-rich foods in your diet to help support bone health, especially while receiving hormone therapy.
  • Avoid smoking and limit alcohol: Do not smoke and limit alcohol consumption, as both can increase the risk of blood clots and cardiovascular problems during hormone therapy.
  • Engage in weight-bearing exercise: Participate in regular activities such as walking or light strength training to help maintain bone density and support heart health.
  • Attend regular health check-ups: Keep all scheduled follow-up appointments, including breast examinations and mammograms, so your doctor can monitor your health during treatment.
     
health query

Have a query?

How Soon It Starts Working

The time required for Vageston 300 mg Capsule to start to work: Vageston 300 mg Capsule ideally shows its action within 2 to 3 hours after administration. 

The time for which the effects of Vageston 300 mg Capsule last: The effect of Vageston 300 mg Capsule lasts for 12 hours.

What if you forget to take Vageston 300 mg Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

• Store Vageston 300 mg Capsule at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Take Vageston 300 mg Capsule at bedtime: Taking Vageston 300 mg Capsule at bedtime may help reduce the impact of daytime drowsiness and dizziness.
  • Use caution during activities requiring alertness: Avoid driving, operating machinery, or performing hazardous tasks immediately after taking Vageston 300 mg Capsule until you know how it affects you.
  • Monitor your breast health: Perform regular breast self-examinations and report any new lumps or unusual breast changes to your doctor promptly.
  • Inform healthcare providers before procedures: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking Vageston 300 mg Capsule before undergoing any medical, surgical, or dental procedure, as temporary interruption of treatment may be necessary.
  • Attend regular monitoring appointments: Keep all scheduled follow-up visits while taking Vageston 300 mg Capsule . Women receiving long-term hormone replacement therapy may require regular assessment of uterine health, breast health, and overall response to treatment.
  • Seek medical advice if concerning symptoms develop: Contact your doctor promptly if you experience unusual vaginal bleeding, severe headaches, vision changes, symptoms of a blood clot, or persistent side effects during treatment.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Anti-seizure medicines (e.g., carbamazepine, phenobarbital): These medicines may reduce the effectiveness of Vageston 300 mg Capsule by increasing its breakdown in the body.
  • Antifungal medicines (e.g., ketoconazole): These medicines may increase the amount of Vageston 300 mg Capsule in the body, raising the risk of side effects.
ProgesteroneEdoxaban
Severe
ProgesteroneMorphine
Severe

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
How does the drug interact with Vageston 300 mg Capsule:
When Vageston 300 mg Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Vageston 300 mg Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneMorphine
Severe
How does the drug interact with Vageston 300 mg Capsule:
Co-administration of Vageston 300 mg Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Vageston 300 mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneVenetoclax
Severe
How does the drug interact with Vageston 300 mg Capsule:
Co-administration of Vageston 300 mg Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Vageston 300 mg Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

verifiedApollotooltip
  • High-fat meals: Taking Vageston 300 mg Capsule with a high-fat meal may increase its absorption and raise the risk of side effects such as drowsiness.
     
PROGESTERONE-300MGCaffeine containing foods/drinks

Drug-Food Interactions

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PROGESTERONE-300MGCaffeine containing foods/drinks
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffiene and its products may interact with Vageston 300 mg Capsule. Limit usage of Caffiene and its products during treatment with Vageston 300 mg Capsule.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Vageston 300 mg Capsule is used in combination with oestrogen for hormone replacement therapy. Besides this, Vageston 300 mg Capsule also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.
Vageston 300 mg Capsule contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.
Vageston 300 mg Capsule may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Vageston 300 mg Capsule and consult a doctor immediately as these might be signs of blood clot.
If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Vageston 300 mg Capsule reduces this risk.
You are recommended to inform your doctor that you are taking Vageston 300 mg Capsule as you may need to stop taking Vageston 300 mg Capsule 4 to 6 weeks before surgery to decrease the risk of blood clot.
Vageston 300 mg Capsule may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.
Vageston 300 mg Capsule should be swallowed as a whole with water. Do not crush or chew it.
Vageston 300 mg Capsule is a hormone extracted from plants and is chemically identical to human progesterone.
Yes, Vageston 300 mg Capsule can be taken daily. Usually, it is taken once everyday in the evening or at bedtime.
Yes, Vageston 300 mg Capsule is safe if taken in the dose and duration prescribed by the doctor.
Progesterone plays a vital role in fertility. It improves the chances of becoming and staying pregnant by preparing the uterus lining.
Vageston 300 mg Capsule may cause side effects like dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. If the side effects persist or worsen, please consult your doctor.
Vageston 300 mg Capsule may be prescribed during early pregnancy in certain situations, such as after fertility treatment, for luteal phase support, or in selected women with threatened miscarriage, when your doctor believes it is beneficial. Do not start or stop Vageston 300 mg Capsule during pregnancy without medical advice.
Taking Vageston 300 mg Capsule at bedtime helps manage common side effects like drowsiness and dizziness, allowing you to sleep through them. Inform your doctor if these symptoms persist.
Some women may experience mild fluid retention or bloating, which can feel like weight gain. If you notice rapid or significant weight changes, talk to your doctor.
It is best to limit or avoid alcohol while taking Vageston 300 mg Capsule , as alcohol can increase drowsiness and may interact with how your body processes the hormone.
The time it takes to see results varies depending on the condition being treated; for restoring periods, withdrawal bleeding usually occurs within a few days of finishing a cycle.
Light spotting or bleeding between periods can sometimes occur, especially during the first few months of treatment. However, if the bleeding is heavy or persistent, consult your doctor immediately.
No, this formulation is not a contraceptive and will not prevent pregnancy. Talk to your doctor about safe and effective birth control methods if you wish to avoid pregnancy.
You should not stop taking this medication without consulting your healthcare provider, as stopping abruptly can cause hormonal imbalances or irregular bleeding. Inform your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad ? 380015, Gujarat, India.
Other Info - VAG0031
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