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compositionComposition:VALGANCICLOVIR-450MG
prescription
Prescription Medicine
info
Valgan Tablet 4's
Valgan Tablet 4's
Valgan Tablet 4's
Valgan Tablet 4's
Valgan Tablet 4's
Valgan Tablet 4's
Valgan Tablet 4's

Valgan Tablet is used to treat cytomegalovirus retinitis (viral infection of the retina). It contains Valganciclovir, which works by inhibiting viral replication. In some cases, this medicine may cause side effects such as diarrhoea, loss of appetite, cough, headache, stomach pain, nausea, fever, and tiredness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALGANCICLOVIR-450MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Valgan Tablet

Valgan Tablet is used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, Valgan Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.

Valgan Tablet contains Valganciclovir, which is converted to ganciclovir in the body and inhibits viral multiplication.

In some cases, you may experience diarrhoea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Valgan Tablet or any other medicines, please tell your doctor. Avoid taking Valgan Tablet if you are pregnant, as it may cause birth defects. If you are breastfeeding, do not take Valgan Tablet as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valgan Tablet and for 30 days after treatment with Valgan Tablet.

Uses of Valgan Tablet

Valgan Tablet is used in the treatment of Cytomegalovirus (CMV) infection of the retina. The detailed uses of Valgan Tablet are as follows:

  • CMV Retinitis: Valgan Tablet treats viral eye infections in patients with AIDS.
  • CMV Prophylaxis: Valgan Tablet prevents CMV disease in organ transplant recipients (kidney, heart, pancreas).

Key Benefits

  • Valgan Tablet contains Valganciclovir, an antiviral drug used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients.
  • Valgan Tablet is converted to ganciclovir in the body and inhibits viral replication.
  • Valgan Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.
Side effects of Valgan Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Limit sugary drinks and foods to reduce yeast growth.
  • Avoid yeast-rich foods like beer, wine, and sourdough bread.
  • Include probiotic-rich foods like yogurt, kefir, kimchi, and sauerkraut.
  • Eat antifungal foods like garlic, onions, cinnamon, and coconut oil.
  • Focus on nutrient-rich foods high in vitamins C and E.
  • Use a warm saltwater rinse in your mouth several times daily.
  • Practice excellent oral hygiene through regular brushing, flossing, and denture cleaning.
  • Stay hydrated by drinking plenty of water.
  • To manage stress, try relaxation methods like deep breathing exercises, meditation, or yoga to help calm your mind and body.
  • Avoid smoking and tobacco to prevent immune function impairment.
  • Consult a doctor for proper diagnosis and treatment.

Directions for Use

  • Valgan Tablet can be taken with food to minimise stomach discomfort or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Valgan Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Valgan Tablet Works

Valgan Tablet contains Valganciclovir, which works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.
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Alcohol

Consult your doctor

The interaction of alcohol with Valgan Tablet is unknown. Please consult a doctor before consuming alcohol while using Valgan Tablet.

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Pregnancy

Unsafe

Valgan Tablet is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Valgan Tablet as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Valgan Tablet may cause dizziness, tiredness, drowsiness, shakiness or confusion in some people. Therefore, avoid driving or operating heavy machinery if you experience any of these symptoms after taking Valgan Tablet.

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Liver

Caution

Take Valgan Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Valgan Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Consult your doctor

Valgan Tablet should be used in children only if recommended by a doctor.

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Heart

Caution

Valgan Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Valgan Tablet.

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Geriatrics

Caution

Limited data is available regarding the use of Valgan Tablet in elderly patients. If you have any concerns about the usage of Valgan Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Valgan Tablet

Take Valgan Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include upset stomach, vomiting, stomach pain, diarrhoea, uncontrolled shaking, seizures, decreased urination, bloody urine, signs of infection (sore throat, fever, chills, cough), excessive tiredness, pale skin, yellowing of skin or eyes, dizziness, fast heartbeat, weakness, and unusual bleeding or bruising. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.

Health Queries

Is it true that herpes zoster cannot be transmitted to others as a different kind of herpes?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Herpes zoster (shingles) is not the same as herpes simplex and cannot spread as a different kind of herpes. Shingles is caused by the varicella-zoster virus, the same virus that causes chickenpox. If someone with shingles has open blisters, the virus can spread to a person who has never had chickenpox or the vaccine, but it will cause chickenpox, not shingles or herpes simplex. Once the blisters dry and form scabs, the infection is no longer contagious. To prevent spreading it, keep the rash covered, avoid touching the blisters, wash your hands often, and stay away from people with weak immune systems, pregnant women, and newborns until the rash heals.

Have a query?

How Soon It Starts Working

  • The time required for Valgan Tablet to start to work: Valgan Tablet ideally shows its action within 2 hours after administration. 
  • The time for which the effects of Valgan Tablet last: The effect of Valgan Tablet lasts for 4 hours.

What if you forget to take Valgan Tablet

If you miss a dose of Valgan Tablet, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Valgan Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are allergic to Valgan Tablet or any other medicines, please tell your doctor.
  • If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valgan Tablet.
  • Avoid taking Valgan Tablet if you are pregnant as it may cause birth defects.
  • If you are breastfeeding, do not take Valgan Tablet as it may be excreted in human milk and cause adverse effects in the baby.
  • Women are recommended to use effective contraceptive measures while taking Valgan Tablet and 30 days after treatment with Valgan Tablet.
  • Men are advised to continue using contraceptive measures for 90 days after treatment with Valgan Tablet.
  • Drive only if you are alert as Valgan Tablet may cause dizziness, tiredness, drowsiness, shakiness or confusion.
  • If you are having blood dialysis or radiotherapy, please inform your doctor before taking Valgan Tablet.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Valgan Tablet may interact with antibiotics (imipenem + cilastatin, trimethoprim, dapsone), gout medicine (probenecid), antifungals (amphotericin B, flucytosine), antiprotozoals (pentamidine), anti-cancer (vinblastine, hydroxyurea, vincristine, doxorubicin), immunosuppressants (tacrolimus, mycophenolate mofetil, ciclosporin), HIV/AIDS medicines (tenofovir, zidovudine, stavudine, didanosine), medicines used to treat hepatitis B infection (adefovir).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have a low platelet count, white blood cell or red blood cell count, or kidney problems, inform your doctor before taking Valgan Tablet.

ValganciclovirCidofovir
Critical
ValganciclovirEtanercept
Severe

Drug-Drug Interactions

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ValganciclovirCidofovir
Critical
How does the drug interact with Valgan Tablet:
Taking cidofovir with Valgan Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Valgan Tablet with Cidofovir is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
ValganciclovirEtanercept
Severe
How does the drug interact with Valgan Tablet:
The combined use of etanercept and Valgan Tablet can increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Valgan Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
ValganciclovirMaribavir
Severe
How does the drug interact with Valgan Tablet:
When Valgan Tablet is used with Maribavir, it may make Valgan Tablet less effective in treating your condition

How to manage the interaction:
Although there is a possible interaction between Valgan Tablet and Maribavir, you can take these medicines together if prescribed by your doctor. If you're having any unusual symptoms, contact a doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirCertolizumab
Severe
How does the drug interact with Valgan Tablet:
Taking Valgan Tablet and Certolizumab may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Valgan Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while urinating - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
ValganciclovirGolimumab
Severe
How does the drug interact with Valgan Tablet:
The combined use of golimumab and Valgan Tablet can increase the risk of infections.

How to manage the interaction:
Although taking Valgan Tablet and Golimumab together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - contact your doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirAdalimumab
Severe
How does the drug interact with Valgan Tablet:
The combined use of adalimumab and Valgan Tablet can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Valgan Tablet and Adalimumab, but it can be taken if prescribed by a doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - reach out to your doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirTenofovir alafenamide
Severe
How does the drug interact with Valgan Tablet:
When Valgan Tablet is taken with Tenofovir alafenamide it may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenofovir alafenamide and Valgan Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
ValganciclovirClozapine
Severe
How does the drug interact with Valgan Tablet:
Taking Clozapine and Valgan Tablet may increase the risk of severe infections.

How to manage the interaction:
Taking Clozapine with Valgan Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not stop using any medications without a doctor's advice.
ValganciclovirZidovudine
Severe
How does the drug interact with Valgan Tablet:
Combining Valgan Tablet with Zidovudine can increase the risk of side effects.

How to manage the interaction:
Although taking Valgan Tablet and Zidovudine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience any complications or symptoms, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ValganciclovirInfliximab
Severe
How does the drug interact with Valgan Tablet:
The combined use of infliximumab and Valgan Tablet can increase the risk of infections.

How to manage the interaction:
Co-administration of Valgan Tablet with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Valgan Tablet is used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, it is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.
Valgan Tablet contains Valganciclovir that works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.
Valgan Tablet may be used to prevent cytomegalovirus infection in patients who received an organ transplant from a donor infected with CMV.
Valgan Tablet may cause diarrhoea as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.
Valgan Tablet should be used with caution in patients with kidney problems and only in doses as prescribed by a doctor. However, regular blood tests are recommended while taking Valgan Tablet to monitor kidney functioning.
You are not recommended to take Valgan Tablet with tacrolimus (immunosuppressant) as it may increase the risk of kidney or nerve damage, cause side effects affecting bone marrow function leading to a low number of blood cells. Therefore, please consult a doctor before taking Valgan Tablet with other medicines.
Valgan Tablet is classed as a cytotoxic medicine and will therefore require special handling.
Common side effects of Valgan Tablet may include diarrhoea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of the side effects of Valgan Tablet do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, it also has activity against the alpha herpesviruses. But it should be taken only if recommended by the healthcare professional.
Valgan Tablet contains Valganciclovir as an active ingredient.
It is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus. In serious cases, it may lead to blindness. CMV retinitis is more likely to affect people with a weakened immune system from HIV/AIDS. The symptoms include blurred vision, a blind spot in vision, floaters in the eye, loss of peripheral vision or flashes in the eye.
Valgan Tablet is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or have any concerns.
If you are breastfeeding, do not take Valgan Tablet as it may be excreted in human milk and cause adverse effects in the baby.
Valgan Tablet may cause dizziness, tiredness, drowsiness, shakiness or confusion in some people. Therefore, avoid driving or operating heavy machinery if you experience these symptoms after taking Valgan Tablet.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.8177 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.6508 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Alganciclovir [Prescribing Information]. 2010. [Accessed on 01 Apr. 2019] Check here
  4. Valgaciclovir [Prescribing Information]. 2025. [Accessed on 09 Mar. 2025] Check here
  5. Fda.gov. 2020. VALCYTE (valganciclovir hydrochloride tablets) [Accessed on 19 March 2025] Check here
  6. Valganciclovir 450 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. [Accessed on 19 March 2025] Check here
  7. Valganciclovir 450 mg Film-coated Tablets -PIL-Electronic Medicines Compendium (EMC). Electronic Medicines Compendium (eMC) [Internet]. Medicines.org.uk. 2019. [Accessed on 2025 Mar 19]Check here

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - VAL0087

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