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  3. Valparex CR-200 Tablet 10's

Valparex CR-200 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Valparex CR-200 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines. It contains Divalproex, which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. It helps block nerve transmission across the brain and provides a calming effect. In some cases, it may cause side effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DIVALPROEX-200MG

Manufacturer/Marketer :

Theo Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Valparex CR-200 Tablet

Valparex CR-200 Tablet is used to treat epilepsy/seizures/fits. Additionally, Valparex CR-200 Tablet is also used to treat manic episodes associated with bipolar disorder and prevent migraines. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Valparex CR-200 Tablet contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Valparex CR-200 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder. 

Take Valparex CR-200 Tablet with or without food. Depending on your medical condition, you are advised to take Valparex CR-200 Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Valparex CR-200 Tablet without consulting your doctor to avoid worsening seizures. Do not take Valparex CR-200 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Valparex CR-200 Tablet . Consult your doctor before taking Valparex CR-200 Tablet if you are breastfeeding. Avoid driving or operating machinery as Valparex CR-200 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Valparex CR-200 Tablet as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Valparex CR-200 Tablet

Valparex CR-200 Tablet is used in the treatment of epilepsy, bipolar disorder, migraine. The detailed uses of Valparex CR-200 Tablet are as follows:<br/> • Seizure Management: Valparex CR-200 Tablet is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.<br/> • Bipolar Disorder Treatment: Valparex CR-200 Tablet can be utilized in the treatment of bipolar disorder, aiding in mood stabilization and reducing the frequency of mood swings.<br/> • Migraine Prevention: Valparex CR-200 Tablet may also be prescribed to prevent migraines, providing relief from recurrent headaches.<br/> • Insomnia Treatment: Valparex CR-200 Tablet can improve sleep quality by inducing sedation, offering relief for those suffering from insomnia or other sleep disturbances.<br/>

Directions for Use

  • Valparex CR-200 Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Valparex CR-200 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Valparex CR-200 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Valparex CR-200 Tablet is used to treat epilepsy/seizures/fits. Also, Valparex CR-200 Tablet is used to treat mood disorders and prevent migraine headaches. Valparex CR-200 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures. Valparex CR-200 Tablet treats mood disorders by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Valparex CR-200 Tablet prevents migraine headaches by limiting the transmission of nerve pain. Valparex CR-200 Tablet is used alone or in combination to treat simple, complex partial, and complex absence seizures. Valparex CR-200 Tablet is used in combination to treat multiple seizures, such as absence seizures.

How Valparex CR-200 Tablet Works

Valparex CR-200 Tablet contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Valparex CR-200 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Valparex CR-200 Tablet
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get help from a health care professional.
  • Manage your feelings and things that trigger them.
  • Fuel your body with good food like fruits, veggies, and whole grains.
  • Find calm through activities like meditation or yoga.
  • Work on changing negative patterns and thoughts.
  • Focus on being healthy overall, not just how you look.
Here are the six steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Managing Medication-Triggered Bronchitis (inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

What if I have taken an overdose of Valparex CR-200 Tablet

Do not take more than the prescribed dose of Valparex CR-200 Tablet as it may cause overdose resulting in heart block, excess sleepiness and deep coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Valparex CR-200 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Valparex CR-200 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Valparex CR-200 Tablet . Valparex CR-200 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Valparex CR-200 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Valparex CR-200 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Valparex CR-200 Tablet . Consult your doctor before taking Valparex CR-200 Tablet if you are breastfeeding. Avoid driving or operating machinery as Valparex CR-200 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Valparex CR-200 Tablet as it could lead to increased dizziness. Care should be taken while giving Valparex CR-200 Tablet to children below 2 years as there is a higher risk of liver intoxication during the first six months of treatment.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateBuprenorphine
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valparex CR-200 Tablet:
Combining Sodium phenylbutyrate and Valparex CR-200 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valparex CR-200 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valparex CR-200 Tablet:
Using buprenorphine together with Valparex CR-200 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valparex CR-200 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Ketamine and Valparex CR-200 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valparex CR-200 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Meropenam and Valparex CR-200 Tablet together can reduce the effect of Valparex CR-200 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valparex CR-200 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Leflunomide and Valparex CR-200 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valparex CR-200 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valparex CR-200 Tablet:
The combined use of Ertapenem and Valparex CR-200 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valparex CR-200 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Vorinostat with Valparex CR-200 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valparex CR-200 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Valparex CR-200 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valparex CR-200 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Lithium with Valparex CR-200 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valparex CR-200 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valparex CR-200 Tablet:
Co-administration of Teriflunomide and Valparex CR-200 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valparex CR-200 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan, help those around you know what to do.

  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Valparex CR-200 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valparex CR-200 Tablet as it may cause increased dizziness.

bannner image

Pregnancy

Unsafe

Valparex CR-200 Tablet belongs to pregnancy category D. Avoid taking Valparex CR-200 Tablet if you are pregnant as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Valparex CR-200 Tablet may pass into breastmilk. Consult your doctor before taking Valparex CR-200 Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Valparex CR-200 Tablet causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

bannner image

Liver

Caution

Valparex CR-200 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Valparex CR-200 Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below two years as they are at a higher risk of liver toxicity.

Have a query?

FAQs

Valparex CR-200 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines.

Valparex CR-200 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Valparex CR-200 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Valparex CR-200 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Valparex CR-200 Tablet may interact with aspirin and cause abnormal side-effects. So, it is recommended to take any medication along with Valparex CR-200 Tablet only after consulting a doctor.

Valparex CR-200 Tablet may improve the symptoms of depression. However, do not use it without consulting a doctor as it may also cause mood disturbances and suicidal thoughts in some patients.

Do not discontinue Valparex CR-200 Tablet without consulting your doctor. To treat your condition effectually, continue taking Valparex CR-200 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Valparex CR-200 Tablet ; your doctor will gradually reduce the dose to avoid worsening seizures.

Before taking Valparex CR-200 Tablet , certain laboratory tests are recommended. These include a Complete Blood Count (CBC), liver function tests (LFTs), kidney function tests, blood urea nitrogen (BUN) and creatinine levels, and a pregnancy test for women of childbearing age. Additionally, blood glucose levels should be checked for patients with diabetes or at risk of developing diabetes. Platelet count and coagulation tests (PT/INR/APTT) are also recommended. Please note that this list may not be exhaustive, and additional tests or monitoring may be necessary based on individual circumstances.

Valparex CR-200 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Valparex CR-200 Tablet .

Topiramate (anticonvulsant) should not be taken along with Valparex CR-200 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It's crucial to consult with your doctor before discontinuing Valparex CR-200 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Valparex CR-200 Tablet is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

Valparex CR-200 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, you must talk to your doctor.

Yes, Valparex CR-200 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Valparex CR-200 Tablet , it's essential to consult with your doctor.

Yes, Valparex CR-200 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Valparex CR-200 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Valparex CR-200 Tablet as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Valparex CR-200 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

Overdose of Valparex CR-200 Tablet can be a severe medical emergency. If you or someone you know has taken an overdose of Valparex CR-200 Tablet , it's crucial to seek immediate medical attention.

Valparex CR-200 Tablet can be taken with or without food. However, it is recommended to take it with food to reduce stomach upset and improve absorption. Food can help buffer any potential stomach irritation and enhance the body's absorption of the medication.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

INDIA

Manufacturer/Marketer address

Theo Pharma Pvt Ltd, 401, Sachet-3, Mirambica School Road, Naranpura, Naranpura
Other Info - VAL0407

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 11:25 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=e26005ef-77f0-4393-a2dc-b5fe460cead8&amp;type=display
  3. https://www.drugs.com/mtm/divalproex-sodium.html
  4. https://www.depakote.com/depakote-formulations

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