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VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat). It contains Dronedarone, which works by blocking abnormal electrical signals in the heart and restoring normal heart rhythm. In some cases, this medicine may cause side effects such as slow heartbeat, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DRONEDARONE-200MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET is an oral prescription medication used to help keep the heart beating normally in adults who have had certain types of irregular heartbeats. It is primarily prescribed to treat people who have experienced temporary or persistent atrial fibrillation or atrial flutter. By stabilizing the heart's electrical system, VALRATE CR 200MG TABLET reduces the risk of serious complications and hospitalizations related to irregular rhythms.

To get the best results, you must take VALRATE CR 200MG TABLET consistently as prescribed by your healthcare provider, usually twice a day. You should always take VALRATE CR 200MG TABLET with food during your morning and evening meals to help your body absorb it properly. Along with taking this medication, adopting heart-healthy habits like a low-sodium diet and avoiding stimulants can further support your heart health.

While taking VALRATE CR 200MG TABLET, you may experience some common, mild side effects such as nausea, diarrhea, or feeling unusually tired. However, you must contact your doctor immediately if you experience serious side effects like sudden breathing difficulties, yellowing of your eyes or skin, or rapid weight gain with swelling in your legs. These symptoms could point to serious liver or heart conditions that require medical attention.

Before starting VALRATE CR 200MG TABLET, you must tell your doctor if you have a history of liver problems, kidney disease, or lung conditions. Do not take this if you have severe heart failure, a very slow heart rate, or a permanent irregular heartbeat that cannot be restored to normal. Your doctor will evaluate your heart health to ensure this treatment is safe for you.

VALRATE CR 200MG TABLET can interact with several other drugs, including blood thinners and other heart medicines, which can lead to dangerous side effects. You should also avoid drinking alcohol or smoking, as they can irritate your heart and strain your liver. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, you must talk to your doctor to understand the risks and benefits.

Uses of VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET is used in the treatment of arrhythmia (irregular heartbeat). The detailed uses of VALRATE CR 200MG TABLET are as follows:

  • Atrial fibrillation: VALRATE CR 200MG TABLET helps keep your heart beating in a steady, normal rhythm if you have a history of temporary or persistent irregular heartbeats, reducing the chance of your heart slipping back into an irregular pattern.
  • Atrial flutter: VALRATE CR 200MG TABLET assists in maintaining a normal heart rate and rhythm in individuals who experience episodes of rapid, fluttery heartbeats, helping to prevent sudden hospital stays.
     

Key Benefits

VALRATE CR 200MG TABLET helps maintain a steady and regular heartbeat, supporting better heart function and overall cardiovascular health. By improving heart rhythm, it helps reduce symptoms and supports a more active daily life. Benefits may include:

  • Helps maintain a regular and steady heart rhythm.
  • Reduces sensations of a racing, fluttering, or pounding heartbeat.
  • Supports improved blood flow and oxygen delivery throughout the body.
  • Helps reduce fatigue, weakness, and shortness of breath during daily activities.
  • Lowers the risk of complications and hospitalisation associated with certain heart rhythm disorders.
  • Improves overall quality of life by supporting healthy heart function.
Side effects of Valrate Cr 200mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.

Directions for Use

  • VALRATE CR 200MG TABLET can be taken with meals for better absorption or as advised by the doctor.
  • Follow your doctor's instructions regarding the dosage and duration for safe and effective treatment.
  • Swallow VALRATE CR 200MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

How VALRATE CR 200MG TABLET Works

VALRATE CR 200MG TABLET contains Dronedarone, which works by blocking certain electrical channels, specifically potassium, sodium, and calcium channels (tiny gates in heart cells that control electrical signals). It also reduces the effects of certain stress hormones on the heart. Together, these actions help calm overactive electrical signals, slow abnormal heart rhythms, and maintain a steady, normal heartbeat.
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Alcohol

Caution

It is advised to limit alcohol intake when you are being treated with VALRATE CR 200MG TABLET.

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Pregnancy

Unsafe

VALRATE CR 200MG TABLET is a pregnancy category X drug, so it is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Please seek medical advice for more information.

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Breast Feeding

Consult your doctor

It is not known if VALRATE CR 200MG TABLET is excreted into the breast milk. Due to possible effects on the breastfed infant, VALRATE CR 200MG TABLET is not recommended for use if you are a nursing mother. Please consult your doctor for more information before taking VALRATE CR 200MG TABLET.

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Driving

Caution

VALRATE CR 200MG TABLET is possibly safe and does not affect your ability to drive. However, if you experience any symptoms that may affect your mental focus and ability to drive, do not drive or operate machinery until you feel better.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver disease before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney disease before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Children

Unsafe

Safety and effectiveness of VALRATE CR 200MG TABLET have not been established in patients below 18 years of age.

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Heart

Safe if prescribed

VALRATE CR 200MG TABLET is safe for use in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Safe if prescribed

VALRATE CR 200MG TABLET is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of VALRATE CR 200MG TABLET

If you take too much of VALRATE CR 200MG TABLET, seek immediate medical attention or contact emergency services right away. An overdose can lead to dangerous changes in your heart rhythm and heart rate, which require urgent medical care.

Diet & Lifestyle Advise

  • Avoid grapefruit entirely: Do not drink grapefruit juice or eat grapefruit, as it can block the enzymes that break down VALRATE CR 200MG TABLET, leading to unsafe levels in your bloodstream.
  • Limit or avoid alcohol: Alcohol can disrupt your heart's electrical rhythm, trigger episodes of irregular heartbeat, and put extra stress on your liver.
  • Reduce caffeine intake: Limit your intake of coffee, tea, energy drinks, and chocolate, as excess caffeine can raise your heart rate and trigger fluttery heartbeats.
  • Adopt a heart-healthy, low-sodium diet: Focus on fresh fruits, vegetables, whole grains, and lean proteins, and cut down on salt to help manage your blood pressure and reduce strain on your heart.
  • Manage physical stress: Engage in light, doctor-approved physical activities like walking to support your cardiovascular system without overworking your heart.
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How Soon It Starts Working

  • The time required for VALRATE CR 200MG TABLET to start to work: VALRATE CR 200MG TABLET ideally shows its action within 3 to 6 hours after administration.
  • The time for which the effects of VALRATE CR 200MG TABLET last: The effect of VALRATE CR 200MG TABLET lasts for 12 to 24 hours.

What if you forget to take VALRATE CR 200MG TABLET

If you miss a dose of VALRATE CR 200MG TABLET, skip the missed dose and take your next scheduled dose at your regular time with your next meal. Do not take two doses at the same time or take an extra dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor your pulse regularly: Check your heart rate frequently and tell your doctor immediately if your pulse drops below 50 beats per minute or feels highly irregular.
  • Keep your blood test appointments: Keep your blood test and ECG (heart tracing) appointments. These help your doctor monitor your heart rhythm, heart rate, and the safety of the medicine during treatment.
  • Watch your breathing: Pay close attention to any new or worsening cough or shortness of breath, as these can be signs of rare but serious lung reactions.
  • Check for interactions: Always tell any healthcare provider (including dentists or surgeons) that you are taking VALRATE CR 200MG TABLET before starting any new prescription, over-the-counter drug, or herbal supplement.
  • Never stop taking VALRATE CR 200MG TABLET suddenly: Discontinuing your treatment abruptly can cause your heart to slip back into an irregular, dangerous rhythm. Always consult your doctor before making changes.
  • Monitor your kidney function: Your blood tests may show a small increase in creatinine after starting VALRATE CR 200MG TABLET. This does not necessarily mean your kidneys are damaged, but your doctor may monitor your kidney function regularly to ensure the medicine remains safe for you.

Drug-Drug Interactions

verifiedApollotooltip
  • Other heart rhythm medicines: Taking these alongside VALRATE CR 200MG TABLET may increase the risk of serious and potentially dangerous heart rhythm problems.
  • Blood thinners (e.g., warfarin): Combining these with VALRATE CR 200MG TABLET may increase the risk of bleeding and require closer monitoring.
  • Heart medicines (e.g., digoxin): VALRATE CR 200MG TABLET may increase digoxin levels in the body, raising the risk of side effects and requiring dose adjustments.
  • Cholesterol-lowering medicines (e.g., simvastatin): Taking these alongside VALRATE CR 200MG TABLET may increase the risk of muscle pain, muscle weakness, or muscle injury.
  • Certain antifungal medicines and antibiotics (e.g., ketoconazole, clarithromycin): These medicines may increase the amount of VALRATE CR 200MG TABLET in the body, raising the risk of serious side effects.
Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valrate Cr 200mg Tablet:
Combining Sodium phenylbutyrate and Valrate Cr 200mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valrate Cr 200mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Using buprenorphine together with Valrate Cr 200mg Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valrate Cr 200mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Meropenam and Valrate Cr 200mg Tablet together can reduce the effect of Valrate Cr 200mg Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Lithium with Valrate Cr 200mg Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Ketamine and Valrate Cr 200mg Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Teriflunomide and Valrate Cr 200mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Vorinostat with Valrate Cr 200mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
The combined use of Ertapenem and Valrate Cr 200mg Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Valrate Cr 200mg Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Leflunomide and Valrate Cr 200mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valrate Cr 200mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Avoid consuming grapefruit products while taking VALRATE CR 200MG TABLET, as they can significantly increase the amount of the medicine in your bloodstream and raise the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIARRHYTHMICS]

FAQs

VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow).
VALRATE CR 200MG TABLET contains Dronedarone, which works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus, VALRATE CR 200MG TABLET helps to treat the uneven heartbeats and helps in normalising the heart rhythm.
Do not stop using VALRATE CR 200MG TABLET even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.
VALRATE CR 200MG TABLET should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).
Store VALRATE CR 200MG TABLET away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.
If you missed a dose, take VALRATE CR 200MG TABLET as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden onset) or persistent atrial fibrillation (irregular heartbeat caused by poor blood flow). Additionally, it is used in ‘cardioversion,' a medical procedure that restores an abnormal heartbeat to a normal rhythm.
Yes, VALRATE CR 200MG TABLET is safe if taken in dose and duration exactly as prescribed by the doctor.
Warning signals of liver toxicity caused by VALRATE CR 200MG TABLET may include dark urine, yellowing of the skin or eyes (jaundice), light-coloured stools, loss of appetite, nausea, vomiting, unusual tiredness, and pain in the upper right side of the abdomen. If you notice any of these symptoms, consult the doctor immediately.
VALRATE CR 200MG TABLET may cause optic neuropathy, the symptoms of optic neuropathy may include blurred vision, sudden vision loss, loss of peripheral vision, difficulty seeing in low light, and pain when moving the eye. If you experience any of these symptoms, consult the doctor immediately.
VALRATE CR 200MG TABLET should be taken orally with or without food at regular intervals. Swallow it as a whole with a glass of water. Do not chew, crush or break it.
The side effects of VALRATE CR 200MG TABLET include diarrhoea, slow heartbeat, nausea and vomiting. Consult the doctor if any of these side effects persist or worsen.
Grapefruit and grapefruit juice interfere with how your body breaks down VALRATE CR 200MG TABLET, which can cause the medicine to build up to dangerous levels in your blood. This increases your risk of serious side effects, including severe heart rhythm issues. Talk to your doctor or pharmacist for safe dietary choices.
These can be signs of serious liver problems. Seek emergency medical attention immediately or contact your doctor without delay. Do not make any changes to your medication unless your healthcare provider advises you to do so.
It is highly recommended to limit or avoid alcohol while taking VALRATE CR 200MG TABLET. Alcohol can irritate the heart muscle, trigger irregular heart rhythms, and increase stress on your liver. Talk to your doctor about safe alcohol consumption limits.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - VAL0053
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