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  3. VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET, Pack of 10 TABLETS
VALRATE CR 200MG TABLET, Pack of 10 TABLETS
VALRATE CR 200MG TABLET, Pack of 10 TABLETS
VALRATE CR 200MG TABLET, Pack of 10 TABLETS
VALRATE CR 200MG TABLET, Pack of 10 TABLETS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat). It contains Dronedarone, which works by blocking abnormal electrical signals in the heart and restoring normal heart rhythm. In some cases, this medicine may cause side effects such as slow heartbeat, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

DRONEDARONE-200MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET belongs to a group of medications known as 'anti-arrhythmic', primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, VALRATE CR 200MG TABLET is also used to treat 'cardioversion', which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate at which the heart beats.

VALRATE CR 200MG TABLET contains 'Dronedarone', a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. VALRATE CR 200MG TABLET blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of the heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take VALRATE CR 200MG TABLET as prescribed by your doctor. Your dose and duration of VALRATE CR 200MG TABLET will be advised by your doctor, depending on your medical condition. In some cases, you may experience a slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of VALRATE CR 200MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to VALRATE CR 200MG TABLET or any other medicines before starting VALRATE CR 200MG TABLET. Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. VALRATE CR 200MG TABLET is not recommended for use during pregnancy. Do not stop taking VALRATE CR 200MG TABLET without consulting your doctor, since it may worsen your condition and increase the risk of future heart problems.

Uses of VALRATE CR 200MG TABLET

VALRATE CR 200MG TABLET is used in the treatment of arrhythmia (irregular heartbeat). The detailed uses of VALRATE CR 200MG TABLET are as follows:<br/> • Maintains normal heart rhythm: VALRATE CR 200MG TABLET helps maintain a normal heartbeat in patients with atrial fibrillation or atrial flutter.<br/> • Reduces hospitalisation risk: VALRATE CR 200MG TABLET reduces the risk of hospital admissions caused by heart rhythm disturbances.<br/> • Supports long-term rhythm control: VALRATE CR 200MG TABLET is often part of a long-term strategy to prevent recurrence of abnormal heart rhythms.<br/>

Directions for Use

  • VALRATE CR 200MG TABLET can be taken with meals for better absorption or as advised by the doctor.
  • Follow your doctor's instructions regarding the dosage and duration for safe and effective treatment.
  • Swallow VALRATE CR 200MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

VALRATE CR 200MG TABLET contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (the lower chambers of the heart (ventricles) beat faster than normal). VALRATE CR 200MG TABLET is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

How VALRATE CR 200MG TABLET Works

VALRATE CR 200MG TABLET contains 'Dronedarone', a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. VALRATE CR 200MG TABLET blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Valrate Cr 200mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.

What if I have taken an overdose of VALRATE CR 200MG TABLET

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Brief your medical history to the doctor if you have any heart problems, liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting VALRATE CR 200MG TABLET. VALRATE CR 200MG TABLET may affect QT prolongation (heart muscle takes longer than usual to recharge between beats), which can cause serious fast/irregular heartbeat. Hence, it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. VALRATE CR 200MG TABLET is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using VALRATE CR 200MG TABLET if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with VALRATE CR 200MG TABLET as it may decrease the efficacy of VALRATE CR 200MG TABLET. VALRATE CR 200MG TABLET is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateTeriflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valrate Cr 200mg Tablet:
Combining Sodium phenylbutyrate and Valrate Cr 200mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valrate Cr 200mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Teriflunomide and Valrate Cr 200mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
The combined use of Ertapenem and Valrate Cr 200mg Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Using buprenorphine together with Valrate Cr 200mg Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valrate Cr 200mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Vorinostat with Valrate Cr 200mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Ketamine and Valrate Cr 200mg Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Valrate Cr 200mg Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valrate Cr 200mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Leflunomide and Valrate Cr 200mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valrate Cr 200mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Lithium with Valrate Cr 200mg Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valrate Cr 200mg Tablet:
Co-administration of Meropenam and Valrate Cr 200mg Tablet together can reduce the effect of Valrate Cr 200mg Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valrate Cr 200mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS
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Alcohol

Caution

It is advised to limit alcohol intake when you are being treated with VALRATE CR 200MG TABLET.

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Pregnancy

Unsafe

VALRATE CR 200MG TABLET is a pregnancy category X drug, so it is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Please seek medical advice for more information.

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Breast Feeding

Caution

It is not known if VALRATE CR 200MG TABLET is excreted into the breast milk. Due to possible effects on the breastfed infant, VALRATE CR 200MG TABLET is not recommended for use if you are a nursing mother. Please consult your doctor for more information before taking VALRATE CR 200MG TABLET.

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Driving

Caution

VALRATE CR 200MG TABLET is possibly safe and does not affect your ability to drive. However, if you experience any symptoms that may affect your mental focus and ability to drive, do not drive or operate machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver disease before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Kidney

Caution

Let your doctor know if you have any history of kidney disease before taking VALRATE CR 200MG TABLET. Your doctor will weigh the benefits and any potential risks before prescribing VALRATE CR 200MG TABLET.

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Children

Unsafe

Safety and effectiveness of VALRATE CR 200MG TABLET have not been established in patients below 18 years of age.

Have a query?

FAQs

VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow).

VALRATE CR 200MG TABLET contains Dronedarone, which works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus, VALRATE CR 200MG TABLET helps to treat the uneven heartbeats and helps in normalising the heart rhythm.

Do not stop using VALRATE CR 200MG TABLET even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.

VALRATE CR 200MG TABLET should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).

Store VALRATE CR 200MG TABLET away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.

If you missed a dose, take VALRATE CR 200MG TABLET as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

VALRATE CR 200MG TABLET is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden onset) or persistent atrial fibrillation (irregular heartbeat caused by poor blood flow). Additionally, it is used in ‘cardioversion,' a medical procedure that restores an abnormal heartbeat to a normal rhythm.

Yes, VALRATE CR 200MG TABLET is safe if taken in dose and duration exactly as prescribed by the doctor.

Warning signals of liver toxicity caused by VALRATE CR 200MG TABLET may include dark urine, yellowing of the skin or eyes (jaundice), light-coloured stools, loss of appetite, nausea, vomiting, unusual tiredness, and pain in the upper right side of the abdomen. If you notice any of these symptoms, consult the doctor immediately.

VALRATE CR 200MG TABLET may cause optic neuropathy, the symptoms of optic neuropathy may include blurred vision, sudden vision loss, loss of peripheral vision, difficulty seeing in low light, and pain when moving the eye. If you experience any of these symptoms, consult the doctor immediately.

VALRATE CR 200MG TABLET should be taken orally with or without food at regular intervals. Swallow it as a whole with a glass of water. Do not chew, crush or break it.

The side effects of VALRATE CR 200MG TABLET include diarrhoea, slow heartbeat, nausea and vomiting. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - VAL0053

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 22, 2025 | 9:24 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022425s013lbl.pdf
  2. https://www.webmd.com/drugs/2/drug-152652/dronedarone-oral/details
  3. https://www.medicines.org.uk/emc/files/pil.10924.pdf
  4. https://www.drugs.com/pregnancy/dronedarone.html

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