Varpress 20 Injection 1 ml belongs to the class of antidiuretic hormones. It is used to treat diabetes insipidus and to control bleeding from esophagal varices. It can also be used to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines. Diabetes insipidus is a rare form of diabetes, causing the production of large quantities of urine.

Varpress 20 Injection 1 ml contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Varpress 20 Injection 1 ml is used to replace it. It also helps treat diabetes insipidus (a rare form of diabetes causing the production of large quantities of urine) by increasing the amount of water reabsorption from the kidneys. Varpress 20 Injection 1 ml helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Varpress 20 Injection 1 ml will be administered by a healthcare professional; do not self-administer. The common side effects of Varpress 20 Injection 1 ml include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication and gradually resolve over time. If the side effects persist longer or worsen, please seek a doctor's advice.

Before starting Varpress 20 Injection 1 ml, let your doctor know if you have any medical history of kidney impairment, cerebral vascular disorder, peripheral arterial disease, ischemic heart disease, congestive heart failure, seizures, asthma, fluid retention, or migraine. While using Varpress 20 Injection 1 ml, avoid drinking large amounts of fluid, including alcohol, since it could lead to the build-up of water in the body. Inform your doctor if you are pregnant or breastfeeding. Varpress 20 Injection 1 ml can cause water intoxication characterised by drowsiness, being uninterested in anything (listless) and headaches. If you notice any of these signs, seek immediate medical help. If it is not corrected, water intoxication can lead to fits or even coma.

Varpress 20 Injection 1 ml is used in the treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices. The detailed uses of Varpress 20 Injection 1 ml are as follows:

• Treatment of Diabetes Insipidus: Varpress 20 Injection 1 ml is used to manage central diabetes insipidus by reducing excessive urine output and restoring fluid balance through antidiuretic hormone activity.
• Management of Bleeding Esophageal Varices: Varpress 20 Injection 1 ml helps control acute gastrointestinal bleeding by constricting blood vessels in the esophagus, reducing blood flow and hemorrhage.
• Support in Vasodilatory Shock: Varpress 20 Injection 1 ml is administered to raise dangerously low blood pressure in patients with septic or vasoplegic shock when other vasopressors are ineffective.
• Adjunct in Surgical and Diagnostic Procedures:Varpress 20 Injection 1 ml may be used to reduce abdominal bloating and improve visualization during certain procedures by decreasing intestinal blood flow and fluid secretion.

• Follow your doctor’s instructions on the dosage and timing of this medication.
• Varpress 20 Injection 1 ml will be administered by a healthcare professional.
• Do not self-administer it.

Varpress 20 Injection 1 ml contains Vasopressin, an antidiuretic (that controls fluid balance) hormone synthesized in the hypothalamus of the pituitary gland. When your body cannot produce enough Vasopressin, Varpress 20 Injection 1 ml is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus. Varpress 20 Injection 1 ml increases plasma levels of factor VIII activity in patients with bleeding disorders. Thus, it helps to control bleeding from esophageal varices. Besides this, Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

It is recommended not to use if you are allergic to vasopressin or any of the other ingredients present in Varpress 20 Injection 1 ml or suffer from any diseases or conditions associated with your blood vessels, especially the blood vessels of your heart, suffer from a certain type of kidney disease called chronic nephritis with nitrogen retention (your doctor will advise you) or if you are intended to receive halogenated anaesthetic agents during surgical procedures. Caution and regular monitoring are essential while using Varpress 20 Injection 1 ml if you have asthma, allergic conditions, migraine, epilepsy (fits), high blood pressure, heart or kidney disease, obstruction of the blood vessels of the heart, or undergone removal of the pituitary gland. So, before taking the Varpress 20 Injection 1 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. It may cause maternal adverse reactions like tonic uterine contractions.