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compositionComposition:VASOPRESSIN-20IU
prescription
Prescription Medicine
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Vascel 20IU Injection 1 ml is used in the treatment of Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices. It contains Vasopressin, a human-made form of Vasopressin. When your body cannot produce enough Vasopressin, Vascel 20IU Injection 1 ml is used to replace it. It also helps treat diabetes insipidus by increasing the amount of water reabsorption from the kidneys. It helps to control bleeding from esophagal varices by increasing plasma levels of factor VIII activity in patients with bleeding disorders.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VASOPRESSIN-20IU

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vascel 20IU Injection 1 ml

Vascel 20IU Injection 1 ml is an injectable form of vasopressin, a hormone that helps control water balance and blood pressure. It may be used in hospital settings to raise dangerously low blood pressure in adults with vasodilatory shock (a severe condition in which blood vessels become too relaxed and blood pressure falls). It has also been used to manage central diabetes insipidus, a condition in which the body does not make enough of the hormone needed to control water balance.

The medicine may be given as an infusion into a vein or as an injection under the skin or into a muscle, depending on why it is being used. In emergencies, it is usually given and closely monitored by healthcare professionals.

Common side effects may include headache, nausea, pale skin, or stomach cramps. Consult your doctor right away if you develop chest pain, an unusual heartbeat, difficulty breathing, severe headache, confusion, or sudden swelling or weight gain.

Before receiving this medicine, tell your doctor if you have heart disease, kidney problems, asthma, migraine, or problems with your body's fluid or salt balance. Also tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Tell your doctor about all medicines you take, particularly medicines that affect blood pressure, heart rate, or fluid balance.
 

Uses of Vascel 20IU Injection 1 ml

Your doctor may prescribe Vascel 20IU Injection 1 ml to help manage the following conditions:

  • Vasodilatory shock: Helps raise dangerously low blood pressure when blood vessels become too relaxed, such as during severe illness or after surgery.
  • Central diabetes insipidus: Helps reduce excessive urination and fluid loss caused by a lack of natural antidiuretic hormone (a hormone that helps the kidneys conserve water).
     

Key Benefits

Vascel 20IU Injection 1 ml helps support blood pressure and fluid balance when the body's natural vasopressin activity is not enough.

  • Supports blood pressure during shock: It narrows blood vessels, helping raise blood pressure and maintain blood flow to vital organs.
  • Reduces excessive urine loss: When used for central diabetes insipidus, it helps the kidneys retain water, reducing frequent urination and excessive thirst.
  • Helps prevent dehydration: By reducing excessive water loss in urine, it can help maintain a healthier fluid balance in people with diabetes insipidus.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Vascel 20IU Injection 1 ml will be administered by a healthcare professional.
  • Do not self-administer it.

How Vascel 20IU Injection 1 ml Works

Vascel 20IU Injection 1 ml contains vasopressin, which acts like a natural hormone in the body that helps control water balance and blood pressure. In the kidneys, this medicine helps the body hold on to water instead of losing too much through urine. This reduces urine production and helps maintain the right amount of fluid in the body. It also narrows blood vessels, which helps raise blood pressure when it becomes dangerously low, such as during severe shock.
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Alcohol

Caution

Avoid consuming alcohol while on treatment with Vascel 20IU Injection 1 ml.

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Pregnancy

Caution

The safety of Vascel 20IU Injection 1 ml in pregnant women is unknown. Therefore, please inform your doctor if you are pregnant or expecting pregnancy; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the treatment to the mother.

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Driving

Caution

Vascel 20IU Injection 1 ml usually does not interfere with your driving ability. Do not drive or operate machinery if you experience unmanageable side effects with Vascel 20IU Injection 1 ml.

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Liver

Caution

Limited information was available about using Vascel 20IU Injection 1 ml in patients with liver disease. Inform your doctor before receiving the Vascel 20IU Injection 1 ml if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Vascel 20IU Injection 1 ml is contraindicated in patients with severe kidney impairment. Please let your doctor know if you have any history of kidney diseases before receiving Vascel 20IU Injection 1 ml.

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Children

Unsafe

Vascel 20IU Injection 1 ml is not recommended in children below 18 years.

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Heart

Caution

Vascel 20IU Injection 1 ml should be used with extreme caution in heart patients due to risks like arrhythmias and reduced cardiac output. If necessary, it must be given under intensive monitoring in a critical care setting.

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Geriatrics

Caution

Vascel 20IU Injection 1 ml may be used in geriatric patients, but with extra caution due to age-related declines in kidney, liver, and heart function. Dosing should typically start low, with close monitoring for side effects like vasoconstriction or electrolyte imbalance.

What if I have taken an overdose of Vascel 20IU Injection 1 ml

Too much vasopressin can cause serious problems, including excessive fluid retention, low sodium levels, high blood pressure, or reduced blood flow to parts of the body. Seek medical attention immediately if an overdose is suspected.

Diet & Lifestyle Advise

  • Follow your fluid plan: Drink the amount of fluid recommended by your healthcare team. Drinking too much or too little may disturb your body's fluid and sodium balance.
  • Monitor your weight when advised: Sudden weight gain may be a sign that your body is retaining too much fluid.
  • Follow dietary advice: Your doctor may recommend changes to your salt or fluid intake depending on your condition.
  • Be cautious with alcohol: Alcohol can affect water balance and urine production. Ask your doctor whether you should avoid it during treatment.
  • Attend regular monitoring: Keep appointments for blood pressure checks and blood tests recommended by your healthcare team.
     
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How Soon It Starts Working

The time required for Vascel 20IU Injection 1 ml to start to work: Vascel 20IU Injection 1 ml ideally shows its action within 1 to 2 minutes after administration. The time for which the effects of Vascel 20IU Injection 1 ml last: The effect of Vascel 20IU Injection 1 ml lasts for 2 to 8 hours.

What if you forget to take Vascel 20IU Injection 1 ml

If you use this medicine according to a scheduled treatment plan and miss a dose, contact your doctor for advice. Do not take a double dose to make up for a missed dose. When the medicine is given as a continuous infusion in hospital, your healthcare team manages the treatment schedule.

Storage

• Store Vascel 20IU Injection 1 ml according to the temperature and storage instructions provided with your product label, typically between 2°C and 8°C for vasopressin injection products that require refrigeration.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Check the solution: Do not use the medicine if it appears cloudy, discoloured, or contains visible particles.
  • Monitor your fluid balance: Follow your doctor's instructions about how much fluid to drink, as too much water retention can cause dangerously low sodium levels.
  • Watch for fluid buildup: Consult your doctor right away if you develop sudden weight gain, severe headache, confusion, unusual drowsiness, nausea, or swelling.
  • Monitor your blood pressure: Vasopressin can raise blood pressure, so regular blood pressure and heart rate checks may be needed.
  • Tell your doctor about heart problems: This medicine narrows blood vessels and may require extra caution if you have heart or blood vessel disease.
  • Tell your doctor about kidney problems: Kidney disease can affect fluid and salt balance, so closer monitoring may be needed.
  • Follow injection instructions carefully: Only give injections outside a healthcare setting if your healthcare professional has trained you to do so.
  • Do not change your fluid intake on your own: Fluid requirements depend on your condition and treatment response.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Diuretics (e.g. furosemide, hydrochlorothiazide): These medicines change how your body handles water and salts and may affect fluid balance during vasopressin treatment.
  • Blood pressure medicines (e.g. propranolol, metoprolol): Medicines that affect blood pressure or heart rate may alter the cardiovascular effects of vasopressin and require closer monitoring.
  • Medicines that can increase water retention (e.g. carbamazepine, chlorpropamide): These medicines may increase the water-retaining effect and raise the risk of low sodium levels or excessive fluid retention.
     
Vasopressin (argipressin)Ziprasidone
Critical
Vasopressin (argipressin)Mifepristone
Severe

Drug-Drug Interactions

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Vasopressin (argipressin)Ziprasidone
Critical
How does the drug interact with Vascel 20IU Injection 1 ml:
Co-administration of Ziprasidone together with Vasopressin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Vascel 20IU Injection 1 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Mifepristone
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Co-administration of vasopressin with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking vasopressin with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Chloroquine
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Using chloroquine together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and vasopressin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Amisulpride
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Using amisulpride together with vasopressin can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Amisulpride and Vascel 20IU Injection 1 ml can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Vasopressin (argipressin)Gatifloxacin
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Taking Gatifloxacin and Vasopressin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Vasopressin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Moxifloxacin
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Using moxifloxacin together with vasopressin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Vascel 20IU Injection 1 ml, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your qt interval. If you have to use it at the same time as something else, make sure to be careful and have regular check-ups with your doctor. Do not stop using any medications without first talking to your doctor.
Vasopressin (argipressin)Sotalol
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Using sotalol together with Vascel 20IU Injection 1 ml can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Vascel 20IU Injection 1 ml, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
Vasopressin (argipressin)Disopyramide
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
The combined use of Vasopressin and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Vasopressin and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Vasopressin (argipressin)Ceritinib
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
Taking Vasopressin with Ceritinib may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Vascel 20IU Injection 1 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations make sure to contact a doctor. Do not discontinue any medications without consulting a doctor.
Vasopressin (argipressin)Hydroxychloroquine
Severe
How does the drug interact with Vascel 20IU Injection 1 ml:
The combined use of vasopressin and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of vasopressin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food  interactions are known with Vascel 20IU Injection 1 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Vascel 20IU Injection 1 ml is used to treat Low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), Diabetes insipidus and to Control bleeding from esophageal varices.
Vascel 20IU Injection 1 ml contains Vasopressin, a human-made form of Vasopressin (antidiuretic hormone). When your body cannot produce enough Vasopressin, Vascel 20IU Injection 1 ml is used to replace it. It helps treat diabetes insipidus. (a rare form of diabetes causing the production of large quantities of urine). Vasopressin increases the amount of water absorbed back into your kidneys. Thus, it helps treat diabetes insipidus.
Vascel 20IU Injection 1 ml increases plasma levels of factor VIII activity in patients with bleeding disorders.
Vasopressin causes vasoconstriction by binding to V1 receptors on vascular smooth muscle. Thus, Vasopressin helps to increase blood pressure in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.
Optimal intake of fluids is recommended to prevent dehydration. However, avoid excess intake of water and other liquids like coffee, tea, cola, and energy drinks during the treatment. Excessive fluid intake while using Vascel 20IU Injection 1 ml may lead to a build-up of water, which dilutes the salt in the body, leading to serious problems.
Vascel 20IU Injection 1 ml is safe when used only under the doctor’s supervision. However, it may cause side effects like nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site.
Vascel 20IU Injection 1 ml should not be taken by people who are allergic to any of its ingredients or have hypersensitivity to 8-L-arginine vasopressin or chlorobutanol.
Vascel 20IU Injection 1 ml is effective in the treatment of low blood pressure (in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines), diabetes insipidus, and to control bleeding from oesophageal varices. However, its effectiveness may vary from person to person.
The common side effects of Vascel 20IU Injection 1 ml include nausea, vomiting, fatigue, fast or irregular heart rate, hyponatremia (low blood sodium levels), ischemia (restriction in blood supply), and redness/pain/swelling at the injection site. These side effects may not occur in everyone using this medication. However, if the side effects persist longer or worsen, please seek a doctor's advice.
Some vasopressin injections may be used outside a healthcare facility when specifically prescribed. You or your caregiver must first be trained by a healthcare professional in how to prepare, inject, and store the medicine safely.
Depending on the condition, this medicine may be given as an infusion into a vein or as an injection under the skin or into a muscle. Your healthcare team will choose the appropriate method.
No. Desmopressin is a medicine made to act like vasopressin, but it mainly helps the kidneys retain water and has much less effect on blood vessels. Desmopressin is more commonly used for central diabetes insipidus. Your doctor will choose vasopressin, desmopressin, or another treatment based on your condition and individual needs.
No. Terlipressin is another medicine related to vasopressin, but it has different effects and is used for different medical conditions. These medicines should not be used interchangeably unless your doctor specifically changes your treatment.
Warning signs can include sudden weight gain, severe headache, nausea, confusion, unusual drowsiness, or swelling. These symptoms may occur when too much water is retained, and the sodium level in your blood becomes too low. Seek medical advice promptly if these symptoms occur.
Yes. Vasopressin narrows blood vessels, which can raise blood pressure. Your healthcare team may monitor your blood pressure and heart rate during treatment. Q: Can I drink alcohol while using this medicine? A: Alcohol can affect urine production and your body's fluid balance. Ask your doctor whether alcohol should be avoided based on why you are receiving this medicine.
Tell your doctor if you are pregnant or planning a pregnancy. Vasopressin can affect the uterus and circulation, so your doctor will carefully consider the benefits and possible risks before using it during pregnancy.

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Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - VAS0059
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