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compositionComposition:IBANDRONIC ACID-150MG
prescription
Prescription Medicine
info
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VEBALONE 150MG TABLET contains ibandronic acid mainly used in the treatment of post-menopausal osteoporosis. It is used for adults with breast cancer or bone metastases to prevent skeletal occurrences such as pathological fractures and bone problems that need surgery or radiation therapy. It mainly works by suppressing the activity of osteoclasts and thereby makes the bone stronger

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IBANDRONIC ACID-150MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About VEBALONE 150MG TABLET

VEBALONE 150MG TABLET is a medicine primarily prescribed to treat and prevent osteoporosis, a condition that makes bones thin, weak, and more likely to break. It is specifically used to protect bone health in women after menopause, helping to maintain bone density and significantly reduce the risk of spine fractures.

To get the best results, this medicine must be taken consistently, typically once a month on the exact same date. You must take VEBALONE 150MG TABLET first thing in the morning on an empty stomach with a full glass of plain water, and wait at least 60 minutes before eating, drinking other liquids, or taking other medicines. Making simple lifestyle choices, such as eating a calcium-rich diet and performing regular weight-bearing exercises, will also support your bone strength.

While taking VEBALONE 150MG TABLET, some people may experience mild side effects like heartburn, stomach pain, or temporary muscle aches. However, you should contact your doctor immediately if you develop serious symptoms, such as severe difficulty swallowing, chest pain, or unusual pain in your jaw or thigh.

Do not take this if you cannot sit or stand upright for at least 60 minutes, have severe kidney disease, or have low levels of calcium in your blood. Talk to your doctor before starting this medicine if you have a history of stomach ulcers, swallowing difficulties, or upcoming major dental work.

Certain supplements like calcium and antacids can stop VEBALONE 150MG TABLET from working properly if taken at the same time, so they must be spaced out carefully. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor or pharmacist before starting this treatment as it is generally not recommended for these groups.

Uses of VEBALONE 150MG TABLET

VEBALONE 150MG TABLET is used to treat and prevent osteoporosis. The detailed uses of VEBALONE 150MG TABLET are as follows:

  • Postmenopausal osteoporosis: Helps increase bone mineral density in women who have gone through menopause, reducing the risk of spinal fractures.
  • Osteoporosis prevention: Helps maintain bone mass in postmenopausal women who are at a higher risk of developing fragile bones.

Key Benefits

VEBALONE 150MG TABLET helps strengthen bones and reduce the risk of fractures by slowing bone loss and improving bone strength. With regular use as prescribed, it supports long-term bone health, mobility, and an active lifestyle.

  • Strengthens Bones: By slowing bone loss, this medicine helps maintain bone density, strengthens the skeleton, and reduces the risk of fractures.
  • Supports Active Mobility: Stronger bones help improve physical stability and allow you to perform daily activities with greater confidence, comfort, and independence.
  • Convenient Monthly Dosing: The once-monthly oral dosing schedule makes it easier to maintain long-term treatment, supporting better adherence and consistent bone health management.

Directions for Use

  • VEBALONE 150MG TABLET should be taken on an empty stomach as food may lower its absorption. It should be taken after you first get up for the day, at least 6 hours after you last had anything to eat or drink except water.
  • It is usually to be taken once a month; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow VEBALONE 150MG TABLET as a whole with a full glass of water.
  • Do not crush, chew, or break it.
  • Avoid lying down, eating, or drinking (except water) for 60 minutes after taking VEBALONE 150MG TABLET.

How VEBALONE 150MG TABLET Works

VEBALONE 150MG TABLET contains ibandronic acid, which belongs to a group of medicines that specifically regulate bone turnover. In a healthy body, bones are constantly being broken down and rebuilt. However, after menopause, bone breakdown often happens faster than bone rebuilding, leading to weaker bones. This medicine works by binding directly to the minerals in your bones and slowing down the activity of specialised cells that break down bone tissue. By reducing this bone loss, it allows your body's bone-building cells to catch up, resulting in denser, stronger bones that are much more resistant to breaks.
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Alcohol

Caution

It is not known if alcohol affects VEBALONE 150MG TABLET. Please consult your doctor.

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Pregnancy

Caution

VEBALONE 150MG TABLET belongs to pregnancy category C. Consult your doctor if you are pregnant. Your doctor will prescribe VEBALONE 150MG TABLET only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if VEBALONE 150MG TABLET passes into breast milk. Consult your doctor before taking this medicine if you are breastfeeding.

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Driving

Safe if prescribed

VEBALONE 150MG TABLET has no or negligible influence on the ability to drive.

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Liver

Caution

Please consult your doctor before taking VEBALONE 150MG TABLET if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

VEBALONE 150MG TABLET is not recommended for people with severe renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

VEBALONE 150MG TABLET is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of VEBALONE 150MG TABLET in heart patients.

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Geriatrics

Consult your doctor

Please consult a doctor before administering VEBALONE 150MG TABLET to geriatric patients. Your doctor will prescribe VEBALONE 150MG TABLET if the benefits outweigh the risks.

What if I have taken an overdose of VEBALONE 150MG TABLET

If you take more than your prescribed dose, seek immediate medical attention. Drink a full glass of milk to help bind the medicine in your stomach, and do not lie down or try to induce vomiting, as this can damage your oesophagus.

Diet & Lifestyle Advise

  • Consume enough calcium and vitamin D: Your bones need these nutrients to rebuild. Ensure your diet includes calcium-rich foods like leafy greens, tofu, and fortified foods, or take supplements as recommended by your doctor.
  • Incorporate weight-bearing exercise: Activities like walking, low-impact aerobics, or light strength training stimulate bone-building cells and improve balance to prevent falls.
  • Avoid smoking: Tobacco use speeds up bone loss and can decrease the effectiveness of your treatment.
  • Limit alcohol intake: Excess alcohol weakens bones and increases your risk of falling, which could lead to fractures.
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How Soon It Starts Working

The time required for VEBALONE 150MG TABLET to start to work: VEBALONE 150MG TABLET ideally shows its action within 1 to 2 hours after administration. The time for which the effects of VEBALONE 150MG TABLET last: The effect of VEBALONE 150MG TABLET lasts for 157 hours.

What if you forget to take VEBALONE 150MG TABLET

If you miss your scheduled monthly dose of VEBALONE 150MG TABLET, look at when your next scheduled dose is due. If your next scheduled dose is more than 7 days away, take one tablet the morning after you remember, and then resume your normal monthly schedule. If your next scheduled dose is less than 7 days away, wait until that scheduled day to take your tablet and skip the missed one. Do not take two tablets within the same week.

Storage

• Store VEBALONE 150MG TABLET tablets at a controlled room temperature between 20°C to 25°C (68°F to 77°F). • Keep the tablets in their original blister packaging until you are ready to take them to protect the medicine from moisture.

Drug Warnings

  • Never take your tablet with mineral water, milk, juice, tea, or coffee, as even small amounts of minerals can completely block the medicine's absorption.
  • Always set a monthly alarm or calendar reminder so you do not forget your dosing day.
  • Make sure to tell your dentist that you are taking VEBALONE 150MG TABLET before you have any dental work, extractions, or surgeries, as this medicine can affect jaw healing.
  • If you experience any new, unusual pain in your groin, hip, or thigh, contact your doctor immediately, as this can be an early sign of an atypical thigh bone fracture.
  • If you must undergo a medical procedure that requires prolonged bed rest, talk to your doctor, as you may need to temporarily pause your medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Calcium supplements, antacids, and iron pills: Can severely decrease how much of this medicine your body absorbs. Take these products at least 60 minutes after taking VEBALONE 150MG TABLET.
  • Aspirin and NSAID pain relievers (like ibuprofen or naproxen): May increase the risk of severe stomach and oesophageal irritation when used alongside VEBALONE 150MG TABLET.
     
Ibandronic acidTacrolimus
Severe
Ibandronic acidTenofovir alafenamide
Severe

Drug-Drug Interactions

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Ibandronic acidTacrolimus
Severe
How does the drug interact with Vebalone 150mg Tablet:
Taking Tacrolimus and Vebalone 150mg Tablet together may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tacrolimus and Vebalone 150mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Ibandronic acidTenofovir alafenamide
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Tenofovir alafenamide with Vebalone 150mg Tablet can increase the risk of kidney damage.

How to manage the interaction:
Taking Vebalone 150mg Tablet with Tenofovir alafenamide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medications without consulting a doctor.
Ibandronic acidSirolimus
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Sirolimus and Vebalone 150mg Tablet may cause an increase in the risk or severity of kidney damage.

How to manage the interaction:
Although taking Vebalone 150mg Tablet and Sirolimus together may lead to an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medication without consulting a doctor.
Ibandronic acidIohexol
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Iohexol with Vebalone 150mg Tablet may increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Vebalone 150mg Tablet and Iohexol, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Ibandronic acidHuman immunoglobulin
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Human immunoglobulin with Vebalone 150mg Tablet may raise the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Human immunoglobulin and Vebalone 150mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Ibandronic acidMetrizamide
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Metrizamide with Vebalone 150mg Tablet may increase the risk or severity of kidney damage

How to manage the interaction:
Taking Vebalone 150mg Tablet with Metrizamide together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Ibandronic acidCidofovir
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Cidofovir with Vebalone 150mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Although taking Vebalone 150mg Tablet and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Ibandronic acidDeferasirox
Severe
How does the drug interact with Vebalone 150mg Tablet:
Co-administration of Deferasirox with Vebalone 150mg Tablet (oral form) may raise your chance of experiencing gastrointestinal (stomach & intestine) bleeding and ulcers.

How to manage the interaction:
Co-administration of Vebalone 150mg Tablet with Deferasirox can result in an interaction, but it can be taken if a doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's essential to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Food and beverages (including milk and dairy): Food, minerals, and drinks other than plain water block the absorption of VEBALONE 150MG TABLET, making it ineffective. Always take it on an empty stomach.

 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BONE ENHANCERS]

FAQs

VEBALONE 150MG TABLET is used to prevent post-menopausal osteoporosis. It is indicated in adults for the prevention of skeletal events such as pathological fractures and bone complications requiring surgery or radiotherapy in patients with bone metastases or breast cancer.
VEBALONE 150MG TABLET suppresses the activity of osteoclasts and makes the bone stronger. It lowers the risk of getting a fracture and reduces pain in the bones.
VEBALONE 150MG TABLET may cause osteonecrosis (bone damage) of the jaw. A full dental check-up is advised before starting VEBALONE 150MG TABLET. Consult your doctor immediately if you experience symptoms such as pain, swelling, redness of the gums, numbness or heaviness in the jaw, and loose teeth. If you are undergoing any dental work, inform the doctor that you are taking VEBALONE 150MG TABLET.
VEBALONE 150MG TABLET may cause unusual fractures of the thigh bone. Consult your doctor if you experience unusual pain in the hip, thigh or groin.
VEBALONE 150MG TABLET may lower the calcium levels in the blood. Call your doctor immediately if you notice symptoms such as spasms, twitches, or cramps in the muscle, numbness, or tingling sensation in the fingers, toes or around the mouth.
VEBALONE 150MG TABLET may cause problems with the oesophagus. To prevent this, take VEBALONE 150MG TABLET precisely as prescribed by the doctor. Consult your doctor if you have chest pain, heartburn, trouble or pain while swallowing.
No, you must stay fully upright (sitting, standing, or walking) for at least 60 minutes after taking VEBALONE 150MG TABLET. This prevents the tablet from moving back into your oesophagus and causing severe irritation or ulcers. Talk to your doctor if you cannot remain upright.
Other drinks, including mineral water, milk, juice, coffee, and tea, contain minerals or nutrients that bind to VEBALONE 150MG TABLET and prevent your body from absorbing it. Talk to your doctor or pharmacist if you are unsure about what you can drink.
You must wait at least 60 minutes after swallowing VEBALONE 150MG TABLET before eating any food, drinking other liquids, or taking other oral medications. Talk to your doctor for personalised advice.
No, calcium supplements block the absorption of this medicine. You should wait at least 60 minutes after taking VEBALONE 150MG TABLET before taking any calcium, vitamins, or other supplements. Talk to your doctor or pharmacist to help schedule your daily medicines.
You should contact your doctor right away. While rare, serious jawbone problems can sometimes occur in patients taking this class of medication, particularly after dental procedures. Talk to your doctor or dentist before getting dental work.
No, VEBALONE 150MG TABLET is generally not recommended for use during pregnancy or while breastfeeding. Talk to your doctor to discuss other treatment options that are safe for you and your baby.
Yes, VEBALONE 150MG TABLET requires adequate levels of calcium and vitamin D in your body to effectively rebuild and strengthen bone. Your doctor will likely recommend daily supplements, but remember to take them at least 60 minutes after your VEBALONE 150MG TABLET tablet. Talk to your doctor before

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Reference

  1. U.S. Food and Drug Administration (FDA). 021455S019Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Ibandronicacid(Cb) - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Ibandronic acid. 2011. [Accessed on 02 Apr. 2019]Check here
  4. Ibandronic acid. 2003. [Accessed on 02 Apr. 2019]Check here
  5. Ibandronate Sodium Tablets [Prescribing Information]. 2022. [Accessed on 05 Jul. 2023]Check here
  6. Ibandronic Acid- Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 25 May 2022]Check here
  7. Maurizio Rossini, Giovanni Orsolini, Silvano Adami, Vidya Kunnathully, Davide Gatti. Osteoporosis treatment: why ibandronic acid? [Accessed on 2nd February 2024]Check here

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - VEB0004
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