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Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Vfend 200 Tablet

Vfend 200 Tablet is used to treat a broad range of infections caused by fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, esophagus, lungs, bladder, genital area and blood.

Vfend 200 Tablet contains ‘Voriconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi which interferes with the fungal cell membrane's formation.

In some cases, you may experience common side effects such as vomiting, headache, nausea, abnormal liver function tests, rash, slow heart rate, and altered vision. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take Vfend 200 Tablet if you have had an allergic reaction to Vfend 200 Tablet or any of its ingredients. Vfend 200 Tablet is associated with liver toxicity, including fatalities in patients with other serious underlying diseases. Vfend 200 Tablet is a pregnancy category D drug, so it should not be taken by breastfeeding and pregnant women. Antacid should be taken at 2 hours after taking Vfend 200 Tablet.

Uses of Vfend 200 Tablet

Vfend 200 Tablet is used to treat fungal infections. The detailed uses of Vfend 200 Tablet are as follows:

  • Treatment of fungal infections: Vfend 200 Tablet helps treat serious fungal infections by preventing fungal growth. It is often prescribed for people with weakened immune systems.
  • Invasive Aspergillosis: Vfend 200 Tablet treats infections caused by Aspergillus fungi.
  • Candidemia: Vfend 200 Tablet helps with bloodstream infections caused by Candida species.
  • Esophageal Candidiasis: Vfend 200 Tablet is effective against fungal infections i the esophagus.
  • Other Severe Fungal Infections: Vfend 200 Tablet is used for Fusarium and Scedosporium infections.

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Directions for Use

  • Vfend 200 Tablet can be taken 1 hour before or 1 hour after meals.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Measure the prescribed dose using the measuring cup provided by the pack and administer it orally.
  • Shake the bottle well before use. Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

  • Vfend 200 Tablet belongs to the class of medicines known as 'antifungal' containing Voriconazole, used to treat a broad range of infections caused due to fungi and yeast.
  • It treats various fungal infections like invasive aspergillosis (fungal infection in the lungs), esophageal candidiasis (white patching in the mouth and throat) and candidemia (a fungal infection in the blood).
  • It is also used to treat certain fungal infections when other medications do not work for certain patients.
  • It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, interfering with the fungal cell membrane's formation.

How Vfend 200 Tablet Works

Vfend 200 Tablet contains Voriconazole that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the fungal cell membrane's formation. As a result, fungal or yeast cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.• Keep Vfend 200 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vfend 200 Tablet
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of Vfend 200 Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include widened pupils, sensitivity to light, drooling, closed eyes, loss of balance while moving, shortness of breath, swollen stomach, extreme tiredness, seizures, and depression. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Vfend 200 Tablet if you have been allergic to any of its ingredients.
  • Vfend 200 Tablet is associated with liver toxicity, including fatalities in patients with other serious underlying diseases.
  • If you are suffering from liver disease, the doctor will lower the dose, and a regular liver function test will be done.
  • Vfend 200 Tablet is a pregnancy category D drug, so it should not be taken by breastfeeding and pregnant women.
  • If you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), please inform your doctor before starting Vfend 200 Tablet.
  • Exposure to sunlight should be avoided while taking Vfend 200 Tablet as it makes you sensitive to the sun's UV rays, or use a high sun protection factor (SPF) while going out.
  • Antacids should be taken 2 hours after taking Vfend 200 Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Vfend 200 Tablet:
Using Vfend 200 Tablet together with Phenobarbital may significantly reduce the blood levels of Vfend 200 Tablet.

How to manage the interaction:
Taking Vfend 200 Tablet with Phenobarbital is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vfend 200 Tablet:
Using Dronedarone together with Dasatinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vfend 200 Tablet with Pimozide is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not discontinue any medicatio0n without consulting a doctor.
How does the drug interact with Vfend 200 Tablet:
Using ivabradine together with Vfend 200 Tablet may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vfend 200 Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vfend 200 Tablet:
Taking Vfend 200 Tablet with Rifampicin can increase blood level of Vfend 200 Tablet.

How to manage the interaction:
Although there is an interaction between Vfend 200 Tablet with Rifampicin, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vfend 200 Tablet:
Using Ticagrelor together with Vfend 200 Tablet can significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Vfend 200 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vfend 200 Tablet:
Using Sparfloxacin together with Vfend 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vfend 200 Tablet with Sparfloxacin is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vfend 200 Tablet:
When Vfend 200 Tablet is taken with Rifabutin, the amount of Vfend 200 Tablet in the blood may decrease.

How to manage the interaction:
Taking Rifabutin with Vfend 200 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vfend 200 Tablet:
Using Lovastatin together with Vfend 200 Tablet may significantly increase the blood levels of Lovastatin.

How to manage the interaction:
Taking Vfend 200 Tablet with Lovastatin is not recommended, please consult a doctor before taking it. You should also seek immediate medical attention if you experience fever, joint pain or swelling, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting a doctor.
VoriconazoleVoclosporin
Critical
How does the drug interact with Vfend 200 Tablet:
Using Voclosporin together with Vfend 200 Tablet may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking Vfend 200 Tablet with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vfend 200 Tablet:
Coadministration of Sirolimus and Vfend 200 Tablet can increase blood levels and side effects of Vfend 200 Tablet.

How to manage the interaction:
Taking Vfend 200 Tablet with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected skin; it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • Avoid taking Vfend 200 Tablet (oral form) with foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola and energy drinks, as it may increase the adverse effects of caffeine.
  • Avoid alcohol intake with Vfend 200 Tablet (oral form) as it may cause adverse effects and increase the risk of liver damage.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods. A very high-sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Unsafe

It is advisable to avoid or limit the intake of alcohol while you use Vfend 200 Tablet.

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Pregnancy

Unsafe

It is unsafe to take Vfend 200 Tablet during pregnancy since it may show harmful effects on the fetus as it is a pregnancy category D drug. There are chances of spontaneous abortions in women treated with Vfend 200 Tablet in the first trimester. Consult your doctor for further advice.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please consult your doctor before taking Vfend 200 Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Do not drive or operate machines if you experience dizziness or sensitivity to sunlight after taking Vfend 200 Tablet.

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Liver

Consult your doctor

Inform your doctor if you have liver problems before taking Vfend 200 Tablet. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems before taking Vfend 200 Tablet. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe Vfend 200 Tablet based on your child's age, condition, and body weight.

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Heart

If you have heart problems, taking Vfend 200 Tablet requires careful medical supervision.

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Geriatrics

Caution

Geriatric patient, taking Vfend 200 Tablet can be beneficial but it requires close monitoring and individualized assessment.

FAQs

Vfend 200 Tablet is used to treat fungal infections.

Vfend 200 Tablet is used to treat a broad range of infections caused by fungi and yeast. It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed, or their growth is minimized.

There is no clinical evidence that Vfend 200 Tablet affects fertility in either men or women.

Vfend 200 Tablet may not be suitable for some people with a weakened immune system, diabetes, cancer or low blood magnesium or potassium levels.

You can take Vfend 200 Tablet with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take Vfend 200 Tablet with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

Country of origin

INDIA

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - VFE0001

Disclaimer

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