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  3. Vibrex 20 Tablet

Vibrex 20 Tablet, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Vibrex 20 Tablet is used to treat the major depressive disorder. It contains Vilazodone which increases serotonin levels and helps regulate mood. In some cases, this medicine may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

VILAZODONE-20MG

Manufacturer/Marketer :

Strides Shasun Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Vibrex 20 Tablet

Vibrex 20 Tablet belongs to the class of medications called ‘antidepressants’ used to treat the major depressive disorder (MDD) or clinical depression. Major depressive disorder, also known as clinical depression, is a mental health disorder characterized by persistent and intense loneliness (nearly every day for at least two weeks).

Vibrex 20 Tablet contains ‘Vilazodone’, which increases serotonin levels (a chemical messenger) in the brain. Serotonin is a hormone that helps improve mood, well-being, and happiness. Hence, an increase in serotonin levels helps to decrease symptoms of depression.

You should take this medicine exactly as prescribed by your doctor. Vibrex 20 Tablet may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). These side effects usually resolve without requiring any treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take Vibrex 20 Tablet if you are allergic to any contents of it. Before taking Vibrex 20 Tablet, inform your doctor if you have seizures (fits), alcohol abuse, liver or kidney disease, bleeding disorder, glaucoma (an eye condition), and bipolar disorder. Vibrex 20 Tablet should be used with caution in pregnant and breastfeeding women. Vibrex 20 Tablet is not recommended for children or adolescents below 18 years of age as this medicine increase the risk of suicidal tendencies. No dose adjustments are required for elderly patients. It is not recommended to take alcohol as it increases the risk of side effects. Do not drive or operate heavy machinery as it may decrease your alertness.

Uses of Vibrex 20 Tablet

Treatment of Major depressive disorder or Clinical depression

Directions for Use

• Vibrex 20 Tablet should be taken with food to enhance absorption and reduce the risk of gastrointestinal side effects.• It is advised to take Vibrex 20 Tablet once daily, at the same time each day, for best results, or as directed by your doctor.• Swallow Vibrex 20 Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Vibrex 20 Tablet is used in the treatment of major depressive disorder. It increases the serotonin hormone levels, which improves mood, energy, and feelings of well-being. It can decrease the number and frequency of depressive episodes. It helps in reducing the symptoms of depression effectively and improves quality-of-life. It can also be used to treat anxiety.

How Vibrex 20 Tablet Works

Vibrex 20 Tablet contains ‘Vilazodone’, which increases serotonin levels (a chemical messenger) in the brain. Serotonin is a hormone that helps improve mood, well-being, and happiness. Hence, an increase in serotonin levels helps to decrease symptoms of depression.

Storage

stored at room temperature below 30°C
Side effects of Vibrex 20 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.

What if I have taken an overdose of Vibrex 20 Tablet

Take Vibrex 20 Tablet only as prescribed by the doctor. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include serotonin syndrome, lethargy, restlessness, hallucinations, and disorientation. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is not recommended to take any monoamine oxidase inhibitors (MAOIs) within the 14 days after stopping Vibrex 20 Tablet or do not take Vibrex 20 Tablet within 14 days after stopping MAOIs. The interaction between these two drugs can be fatal sometimes. Vibrex 20 Tablet may worsen depression and increase suicidal tendencies, so inform your doctor immediately if you notice any unusual changes in your mood or behaviour. Vibrex 20 Tablet may cause serotonin syndrome or neuroleptic malignant-like syndrome, which is characterized by symptoms such as high blood pressure, agitation, confusion, excess sweating, and increased heart rate. In such cases, the doctor may discontinue treatment and provide supportive therapy. Vibrex 20 Tablet may increase bleeding risk when used along with nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, or blood thinners. Vibrex 20 Tablet may activate mania (abnormally heightened response or energy levels), so patients should be screened regularly for bipolar disorder. Vibrex 20 Tablet may cause hyponatremia (decreased sodium levels in the blood) when used in people with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), a condition in which the body retains too much water. Do not stop taking Vibrex 20 Tablet even if you feel better without your doctor’s advice. Abrupt stopping this medicine may cause withdrawal symptoms such as sleep problems, irritability, and excessive sweating. The doctor may gradually reduce the dose before completely stopping the treatment from avoiding withdrawal reactions.

Drug-Drug Interactions

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VilazodoneFurazolidone
Critical
VilazodoneLinezolid
Critical

Drug-Drug Interactions

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VilazodoneFurazolidone
Critical
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Furazolidone, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Furazolidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneLinezolid
Critical
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Linezolid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Linezolid together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodonePhenelzine
Critical
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Phenelzine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Phenelzine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneIsocarboxazid
Critical
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Isocarboxazid, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Isocarboxazid together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneProcarbazine
Critical
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Procarbazine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Procarbazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneRasagiline
Critical
How does the drug interact with Vibrex 20 Tablet:
Taking Vibrex 20 Tablet and Rasagiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Rasagiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneTranylcypromine
Critical
How does the drug interact with Vibrex 20 Tablet:
Taking Vibrex 20 Tablet with Tranylcypromine can increase the risk of serotonin syndrome (a A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Tranylcypromine can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneSafinamide
Critical
How does the drug interact with Vibrex 20 Tablet:
Taking Safinamide with Amitriptyline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Safinamide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
VilazodoneSelegiline
Critical
How does the drug interact with Vibrex 20 Tablet:
Co-administration of Vibrex 20 Tablet is taken with Selegiline, which increases the serotonin levels (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Vibrex 20 Tablet with Selegiline together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, shaking, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VilazodoneClomipramine
Severe
How does the drug interact with Vibrex 20 Tablet:
When Vibrex 20 Tablet is taken with Clomipramine, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vibrex 20 Tablet and Clomipramine, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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VILAZODONE-20MGHerbal products/medicines
Moderate

Drug-Food Interactions

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VILAZODONE-20MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking Vibrex 20 Tablet with St. John's Wort significantly increases the metabolism of Vibrex 20 Tablet. Avoid taking Vibrex 20 Tablet with St. John's Wort.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitters' proper maintenance.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges, and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors, and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Vibrex 20 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol as it may interact with Vibrex 20 Tablet and increase the risk of side-effects.

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Pregnancy

Caution

Vibrex 20 Tablet should be used in pregnant women only when clinically needed and if the benefits outweigh the risks. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Vibrex 20 Tablet.

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Breast Feeding

Caution

Vibrex 20 Tablet should be used in breastfeeding mothers when clinically needed and if the benefits outweigh the risks. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Vibrex 20 Tablet.

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Driving

Caution

Do not drive or operate heavy machinery as Vibrex 20 Tablet may affect alertness.

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Liver

Caution

Vibrex 20 Tablet should be used with caution in patients with severe liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Vibrex 20 Tablet should be used with caution in patients with severe kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Vibrex 20 Tablet is not recommended in children below 12 years of age.

Have a query?

FAQs

Vibrex 20 Tablet is used to treat major depressive disorder or clinical depression.

Vibrex 20 Tablet contains 'vilazodone' which is an antidepressant. It works by restoring the levels of serotonin in the brain. Serotonin is a hormone or chemical messenger in the brain responsible for improving energy, mood, and emotion levels.

Vibrex 20 Tablet may cause side effects such as diarrhoea, nausea, vomiting, and insomnia (sleeping problems). These side effects usually resolve without requiring any treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

In case you miss a dose of Vibrex 20 Tablet, do not take a double dose of Vibrex 20 Tablet. If you remember the missed dose before sleeping, take it at that time and take Vibrex 20 Tablet at the same time the next day, which were you taking earlier. If you remember the missed dose the next day, leave the skipped dose, and continue with the next dose.

Yes,Vibrex 20 Tablet cause withdrawal symptoms, if you suddenly stop your medicine even if u feel better. Please reach out a health care professional.

Vibrex 20 Tablet cannot be used in epilepsy or are having electroconvulsive treatment .Vibrex 20 Tablet may increase your risk of having a seizure.

Vibrex 20 Tablet should be used with caution in patients with alcohol abuse, seizures (fits), liver or kidney disease, bleeding disorder, glaucoma (an eye condition), and bipolar disorder, as the Vibrex 20 Tablet may worsen these conditions.

No, Vibrex 20 Tablet is not a narcotic. It is an antidepressant medication that belongs to the class of selective serotonin reuptake inhibitors (SSRIs).

Yes, Vibrex 20 Tablet can help with anxiety. While it is primarily used to treat major depressive disorders, it has also been shown to be effective in reducing symptoms of anxiety.

Vibrex 20 Tablet is not approved for use in children and adolescents under 18 years old due to the increased risk of suicidal thoughts and behavior.

Before taking Vibrex 20 Tablet, it's essential to inform your doctor about your medical history, including any ongoing medications and existing conditions such as seizures, liver or kidney disease, bipolar disorder, or pregnancy. Additionally, share your history of suicidal thoughts or behavior and any relevant family history. By sharing this information, you'll help your doctor avoid potential drug interactions, minimize side effects, and choose the best treatment for you.

Major Depressive Disorder, or clinical depression, is characterized by a persistent depressed mood that lasts nearly every day for two weeks, interfering with daily activities. Symptoms include feeling sad or hopeless, loss of interest in usual activities, weight/appetite changes, sleep disturbances, agitation, fatigue, guilt/worthlessness, concentration problems, and suicidal thoughts/behavior, with at least five of these symptoms present.

Country of origin

India

Manufacturer/Marketer address

Strides Shasun Limited, (Formerly Strides Arcolab Limited), Strides House, Bilekahalli, Bannerghatta Road, Bangalore – 560076, India
Other Info - VIB0052

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:46 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.nhs.uk/conditions/ssri-antidepressants/
  2. https://www.webmd.com/drugs/2/drug-155880/viibryd-oral/details
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022567s000lbl.pdf
  4. https://www.drugs.com/cdi/vilazodone.html

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