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  3. Voage-MS 500 Tablet 15's

Voage-MS 500 Tablet 15's, Pack of 15 TabletS
Voage-MS 500 Tablet 15's, Pack of 15 TabletS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Voage-MS 500 Tablet is an antidiabetic medicine used to treat Type II Diabetes as an adjunct to diet and exercise. It contains Dapagliflozin (which removes excess sugar from the body via urine), Sitagliptin (which works by increasing the amounts of certain natural substances that lower blood sugar when it is high) and Metformin (which works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines).

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Composition :

DAPAGLIFLOZIN-10MG + METFORMIN-500MG + SITAGLIPTIN-100MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Voage-MS 500 Tablet

Voage-MS 500 Tablet is an antidiabetic medicine used to treat Type II Diabetes. In type 2 diabetes, the pancreas does not produce enough insulin, or the body is unable to use insulin effectively. As a result, blood sugar levels become elevated.

Voage-MS 500 Tablet contains Dapagliflozin, Sitagliptin, and Metformin. It works by removing excess sugar from the body through urine, increasing the levels of certain natural substances that lower blood sugar when it is high, reducing sugar production by cells in the liver, and delaying sugar absorption from the intestines.

Take Voage-MS 500 Tablet as advised by your doctor. Voage-MS 500 Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and stomach upset. Most of these side effects do not need medical attention and resolve over time. If these side effects persist or worsen, please consult your doctor.

Do not take Voage-MS 500 Tablet if you are allergic to any of its components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Voage-MS 500 Tablet . Let your doctor know if you are pregnant or breastfeeding before taking Voage-MS 500 Tablet . It is not recommended for use in children below 18 years of age.

Uses of Voage-MS 500 Tablet

Voage-MS 500 Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Voage-MS 500 Tablet are as follows:

  • Type 2 Diabetes Management: Voage-MS 500 Tablet is used to improve blood sugar control in adults with type 2 diabetes. It combines three agents that work together to reduce glucose production, enhance insulin response, and promote glucose excretion through urine.
  • Cardiovascular and Kidney Protection: Voage-MS 500 Tablet helps lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.
  • Weight and Metabolic Control: Voage-MS 500 Tablet supports weight loss and improves metabolic health by reducing excess glucose and enhancing insulin sensitivity, making it beneficial for overweight or obese diabetic patients.
  • HbA1c Reduction and Glycemic Stability: Voage-MS 500 Tablet effectively lowers HbA1c levels and helps maintain steady blood sugar throughout the day, reducing the risk of hypoglycemia and long-term complications.

Directions for Use

  • Take Voage-MS 500 Tablet with food to reduce stomach upset or gastrointestinal side effects.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Voage-MS 500 Tablet is a combination of three antidiabetic medicines: Sitagliptin, Dapagliflozin, and Metformin, used in the management of Type 2 Diabetes Mellitus, along with proper diet and exercise.
  • Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin release and decrease glucagon levels in the body, lowering blood sugar levels when they are high.
  • Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by removing excess glucose through the urine, thereby lowering blood sugar levels.
  • Metformin is a biguanide which reduces the amount of sugar produced by the liver and delays glucose absorption from the intestine.
  • It improves the body’s sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
  • The combined effect of these three drugs offers multi-targeted control of blood sugar levels, especially in patients not controlled by single or dual therapy.
  • Voage-MS 500 Tablet helps manage blood glucose levels and prevents diabetes-related complications, such as eye problems, nerve problems, and kidney impairment.

How Voage-MS 500 Tablet Works

Voage-MS 500 Tablet contains Dapagliflozin, Sitagliptin, and Metformin. Dapagliflozin removes excess sugar from the body via urine. Sitagliptin works by increasing the amounts of certain natural substances that lower blood sugar when it is high. Metformin works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines.

Storage

• Store in a cool and dry place away from sunlight.• Keep Voage-MS 500 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Voage-MS 500 Tablet
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Voage-MS 500 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Voage-MS 500 Tablet may include low blood sugar, stomach pains, feeling or being sick (nausea or vomiting), feeling dizzy and worried. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

  • Voage-MS 500 Tablet should be avoided if you are allergic to any of the components in it.
  • Before starting treatment, inform your doctor about your medical history and the medications you are taking, including any herbs and supplements. This can help prevent unwanted effects.
  • Voage-MS 500 Tablet is not recommended for use in patients with severe liver or kidney disease.
  • Consult your doctor if you are pregnant or breastfeeding.
  • It is not recommended for use in children below 18 years of age.
  • Avoid drinking alcohol while on Voage-MS 500 Tablet  as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).

Drug-Drug Interactions

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DapagliflozinGatifloxacin
Critical
MetforminIopentol
Critical

Drug-Drug Interactions

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DapagliflozinGatifloxacin
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Voage-MS 500 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Voage-MS 500 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
MetforminIopentol
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Iopentol with Voage-MS 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Voage-MS 500 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Voage-MS 500 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Voage-MS 500 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Iopromide with Voage-MS 500 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Voage-MS 500 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminMetrizamide
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Voage-MS 500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Voage-MS 500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIobenzamic acid
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Voage-MS 500 Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Voage-MS 500 Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Ioglycamic acid with Voage-MS 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Voage-MS 500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Iopydol with Voage-MS 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Voage-MS 500 Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Voage-MS 500 Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Voage-MS 500 Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Voage-MS 500 Tablet:
Co-administration of Iopanoic acid with Voage-MS 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Voage-MS 500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
  • Include whole-grain foods, fruits and veggies, and other fibre-enriched foods.
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
  • Weight loss gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Voage-MS 500 Tablet .
  • Take short, frequent meals, and avoid prolonged fasting when taking Voage-MS 500 Tablet .

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Voage-MS 500 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Voage-MS 500 Tablet .

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Pregnancy

Consult your doctor

There are no adequate studies on the effect of Voage-MS 500 Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Voage-MS 500 Tablet .

bannner image

Breast Feeding

Caution

Voage-MS 500 Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Voage-MS 500 Tablet .

bannner image

Driving

Safe

Voage-MS 500 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Voage-MS 500 Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Voage-MS 500 Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Voage-MS 500 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Have a query?

FAQs

Voage-MS 500 Tablet is used to treat type II diabetes mellitus, a condition wherein the body doesn't use insulin effectively, which causes unusual blood glucose levels.

Voage-MS 500 Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.

If you forget to take Voage-MS 500 Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double-dose to make up the missed dose. Taking an overdose might cause your sugar level to fall rapidly.

Voage-MS 500 Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,India
Other Info - VOA0009

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 11:12 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a606023.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
  4. https://www.drugs.com/metformin.html
  5. https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/#:~:text=Sitagliptin%20is%20prescribed%20for%20people,is%20only%20available%20on%20prescription.

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