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compositionComposition:EXEMESTANE-25MG
prescription
Prescription Medicine
info
Xamalon 25mg Tablet

Xamalon 25mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Exemestane, which prevents the growth of cancer cells. Thus, it helps to prevent the spreading of tumours (cancer cells) to other body parts. It may cause common side effects such as insomnia (difficulty sleeping), nausea, headache, musculoskeletal (bone, muscle, or joint) pain, increased sweating, and overtiredness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EXEMESTANE-25MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Xamalon 25mg Tablet

Xamalon 25mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.

Xamalon 25mg Tablet contains Exemestane, which works by blocking the aromatase enzyme, which produces the estrogen hormone. Thus, it lowers the amount of estrogen (the natural female hormone) produced in the body.

In some cases, you may experience common side effects such as difficulty sleeping, nausea, headache, musculoskeletal pain, increased sweating, and fatigue. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Xamalon 25mg Tablet should not be taken in conditions like liver and kidney disease. Talk to your doctor before taking Xamalon 25mg Tablet if you have any type of allergy with Xamalon 25mg Tablet or any part of Xamalon 25mg Tablet. Xamalon 25mg Tablet should not be taken if you are pregnant or planning to become pregnant or breastfeeding. Xamalon 25mg Tablet should not be given to children as safety has not been established.

Uses of Xamalon 25mg Tablet

Xamalon 25mg Tablet is used in the treatment of breast cancer in women. The detailed uses of Xamalon 25mg Tablet are as follows:

  • Treats Breast Cancer in Postmenopausal Women: Xamalon 25mg Tablet is used to treat early-stage, hormone receptor-positive breast cancer in women after menopause (cessation of periods) by reducing estrogen levels, which drives the growth of cancer cells.
  • Maintenance Therapy to Prevent Cancer Recurrence: Xamalon 25mg Tablet is often prescribed after 2-3 years of tamoxifen therapy (hormone treatment) to reduce the risk of breast cancer recurrence by further suppressing estrogen production.
  • Treats Advanced or Metastatic Breast Cancer: Xamalon 25mg Tablet is also used to treat advanced hormone receptor-positive breast cancer in postmenopausal women when other hormonal therapies have not been effective.

Key Benefits

  • Xamalon 25mg Tablet is used to treat specific types of breast cancer in women after menopause.
  • Xamalon 25mg Tablet is also used to help prevent cancer from returning. Some breast cancers are made to grow faster by a natural hormone known as estrogen.
  • Xamalon 25mg Tablet works by blocking the aromatase enzyme, which is involved in producing the estrogen hormone.
  • Xamalon 25mg Tablet lowers the amount of estrogen in the body.
  • Xamalon 25mg Tablet helps prevent or stop the growth of the tumours (cancer cells) from spreading to other body parts.
Side effects of Xamalon 25mg Tablet
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • If you notice any changes in your blood test results, especially if you are taking medicines that can affect clotting time, consult your doctor so that they may adjust the dose or recommend alternative medicine with lower risk.
  • Be aware of possible signs like nosebleeds, easy bruising, or heavy menstrual bleeding.
  • Consult your doctor to determine potential causes of increased PTT (Partial thromboplastin time), such as clotting factor deficiencies or medication effects, and recommend appropriate treatment.
  • Your doctor may adjust medications if they are causing increased PTT.
  • Eat vitamin K-rich foods like leafy greens and essential nutrients to support normal blood clotting.
  • Take precautions like wearing protective gear to prevent injuries.
  • Inform your doctor if you experience severe bleeding, such as heavy periods or bleeding that doesn’t stop after 10–15 minutes of pressure.
  • Be alert for symptoms of bleeding, such as easy bruising, extended bleeding from cuts, gum or nosebleeds, heavy menstrual periods, or blood in your stool or urine.
  • Follow your doctor's advice regarding blood-thinning medications.
  • Limit foods that are high in vitamin K, such as kale, spinach, broccoli, and Brussels sprouts, if your doctor advises.
  • Avoid activities that may lead to injury or increase bleeding risks.
  • If you suspect severe bleeding, seek medical help right away.
  • Follow regular check-ups to assess your blood clotting status and any necessary modifications to your treatment.

Directions for Use

  • Xamalon 25mg Tablet can be preferably taken after meals.
  • Take Xamalon 25mg Tablet once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Xamalon 25mg Tablet Works

Xamalon 25mg Tablet works by blocking the aromatase enzyme, which produces the estrogen hormone. Thus, it lowers the amount of estrogen (the natural female hormone) produced in the body. Cancer cells require estrogen for their growth. Hence, blocking the aromatase enzyme prevents the growth of cancer cells. Together, Xamalon 25mg Tablet helps prevent or stop the spread of tumours (cancer cells) to other body parts.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Xamalon 25mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Xamalon 25mg Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Xamalon 25mg Tablet should not be used during pregnancy because it causes harm to your fetus (newborn baby). Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Breast Feeding

Unsafe

Xamalon 25mg Tablet should not be taken during breastfeeding as it may harm your baby. Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Driving

Unsafe

Xamalon 25mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver diseases, please consult a doctor before taking Xamalon 25mg Tablet. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have or had a history or evidence of any kidney diseases, please consult a doctor before taking Xamalon 25mg Tablet. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Xamalon 25mg Tablet should not be used by children, as efficacy and safety have not been established.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Xamalon 25mg Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Xamalon 25mg Tablet

Do not take more than the prescribed dose of Xamalon 25mg Tablet as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep, rest well.

Have a query?

How Soon It Starts Working

  • The time required for Xamalon 25mg Tablet to start to work: The time required for Xamalon 25mg Tablet to show its action is not clinically established. 
  • The time for which the effects of Xamalon 25mg Tablet last: The duration of action for Xamalon 25mg Tablet is not clinically established.

What if you forget to take Xamalon 25mg Tablet

Take the missed dose as soon as you can. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not double the dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • To treat your condition effectually, continue taking Xamalon 25mg Tablet for as long as your doctor has prescribed. Do not stop Xamalon 25mg Tablet midway.
  • Do not take Xamalon 25mg Tablet if you are allergic to any of its contents. $
  • Xamalon 25mg Tablet should not be taken in conditions like liver and kidney disease.
  • Before taking Xamalon 25mg Tablet inform your doctor if you have osteoporosis, as Xamalon 25mg Tablet may increase your risk of developing osteoporosis. I
  • f you have not yet gone through menopause, i.e. if you still have periods, then immediately inform your doctor before taking Xamalon 25mg Tablet.
  • Xamalon 25mg Tablet should not be taken If you are pregnant or planning to become pregnant or breastfeeding.
  • Xamalon 25mg Tablet causes weakness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol with Xamalon 25mg Tablet as it could lead to increased drowsiness and dizziness.
  • Xamalon 25mg Tablet should not be given to children as safety has not been established.
  • Xamalon 25mg Tablet may have an intolerance to some sugar. Inform your doctor before taking this Xamalon 25mg Tablet.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Xamalon 25mg Tablet may interact with an antibiotic (rifampicin) and medicines used to treat fits/epilepsy (carbamazepine, phenytoin).

Food-Drug Interactions: No food interaction was found.

Drug-Disease Interactions: Xamalon 25mg Tablet should not be given to patients with osteoporosis and vitamin D deficiency.

ExemestaneDiethylstilbestrol
Severe
ExemestaneConjugated Estrogens
Severe

Drug-Drug Interactions

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ExemestaneDiethylstilbestrol
Severe
How does the drug interact with Xamalon 25mg Tablet:
Co-administration of Xamalon 25mg Tablet with Diethylstilbestrol may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xamalon 25mg Tablet with Diethylstilbestrol together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneConjugated Estrogens
Severe
How does the drug interact with Xamalon 25mg Tablet:
Coadministration of Conjugated estrogens with Xamalon 25mg Tablet may reduce the effect of Xamalon 25mg Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Xamalon 25mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
ExemestaneDienestrol
Severe
How does the drug interact with Xamalon 25mg Tablet:
Co-administration of Xamalon 25mg Tablet with Dienestrol may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xamalon 25mg Tablet and Dienestrol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneThalidomide
Severe
How does the drug interact with Xamalon 25mg Tablet:
Taking thalidomide together with Xamalon 25mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Xamalon 25mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ExemestaneEstramustine
Severe
How does the drug interact with Xamalon 25mg Tablet:
Co-administration of Xamalon 25mg Tablet with Estramustine may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Xamalon 25mg Tablet and Estramustine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneEstrone
Severe
How does the drug interact with Xamalon 25mg Tablet:
Co-administration of Xamalon 25mg Tablet with Estrone may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Co-administration of Xamalon 25mg Tablet with Estrone can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneEstradiol
Severe
How does the drug interact with Xamalon 25mg Tablet:
Using Estradiol with Xamalon 25mg Tablet may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xamalon 25mg Tablet and Estradiol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneEthinylestradiol
Severe
How does the drug interact with Xamalon 25mg Tablet:
When used with Ethinylestradiol, the effectiveness of Xamalon 25mg Tablet might be reduced.

How to manage the interaction:
Although taking Xamalon 25mg Tablet and Ethinylestradiol together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ExemestaneChlorotrianisene
Severe
How does the drug interact with Xamalon 25mg Tablet:
Co-administration of Xamalon 25mg Tablet with Chlorotrianisene may interfere with Xamalon 25mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xamalon 25mg Tablet with Chlorotrianisene together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Xamalon 25mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods).
The most common side effects of using Xamalon 25mg Tablet are hot flashes, joint pain, feeling tired, trouble sleeping, headache, depression, increased sweating, upset stomach, feeling anxious, and difficulty breathing. If any of these side effects disturb you, inform your doctor.
The common symptoms of breast cancer involve the presence of a lump in the breast that feels different from the rest of the breast tissue. You may observe changes in the size, shape and appearance of the breast. The nipple becomes enlarged and painful, and discharge is also one of the symptoms of breast cancer. Pain occurs around the breast.
Yes, Xamalon 25mg Tablet commonly affects the hair by making it thin, which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xamalon 25mg Tablet. These effects are not long-lasting and may return after some time. If it matters to you, inform your doctor of another alternative medicine to avoid harm to your hair.
Xamalon 25mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
Although there is no known way to prevent breast cancer, there are ways to lower your risk. It is advisable to drink less alcohol, stay at a healthy weight, get regular exercise, breastfeed (completely breastfeeding during your baby's first 6 months and continuing for 12 months or longer), and inform your doctor about hormone replacement therapy (a form of hormone therapy used to treat symptoms related with female menopause) if you take it.
Take Xamalon 25mg Tablet with or without food as advised by your doctor. The number of doses and the duration depend on your medical condition. Take it roughly at the same time every day to ensure consistent levels of Xamalon 25mg Tablet in your body. You may need to take Xamalon 25mg Tablet for several years, and the treatment may be long-term.
If you forget to take a dose of Xamalon 25mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose on time. Do not double the dose to make up for the missed one, as this may increase the risk of side effects.
Xamalon 25mg Tablet is safe if used as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects persist or worsen.
Do not stop taking Xamalon 25mg Tablet without talking to your doctor, even if you feel better as it may worsen your condition.
Store Xamalon 25mg Tablet at room temperature, protected from moisture. Keep it out of reach of children.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Exemestane Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.4664 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Exemestane Exemestane. 1999. [Accessed on 03 Apr. 2019] Check here
  4. Exemestane [Prescribing Information]. 2018. [Accessed on 20 Feb. 2024] Check here
  5. Giorgia Zucchini, Elena Geuna, Andrea Milani, Caterina Aversa, Rossella Martinello, and Filippo Montemurro. Clinical utility of exemestane in the treatment of breast cancer. International Journal of women’s health. May 2015. [Accessed on 14th May] Check here
  6. Glenmark Pharmaceuticals limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 14th May] Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 04 Apr. 2019]Check here

Country of origin

India
Other Info - XA40549
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