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compositionComposition:EXEMESTANE-25MG
prescription
Prescription Medicine
info
Zemasin Tablet 25 10's

Zemasin Tablet 25 10's is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Exemestane, which prevents the growth of cancer cells. Thus, it helps to prevent the spreading of tumours (cancer cells) to other body parts. It may cause common side effects such as insomnia (difficulty sleeping), nausea, headache, musculoskeletal (bone, muscle, or joint) pain, increased sweating, and overtiredness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EXEMESTANE-25MG

Manufacturer/Marketer :

Oncozest

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zemasin Tablet 25 10's

Zemasin Tablet 25 10's is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.

Zemasin Tablet 25 10's contains Exemestane, which works by blocking the aromatase enzyme, which produces the estrogen hormone. Thus, it lowers the amount of estrogen (the natural female hormone) produced in the body.

In some cases, you may experience common side effects such as difficulty sleeping, nausea, headache, musculoskeletal pain, increased sweating, and fatigue. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Zemasin Tablet 25 10's should not be taken in conditions like liver and kidney disease. Talk to your doctor before taking Zemasin Tablet 25 10's if you have any type of allergy with Zemasin Tablet 25 10's or any part of Zemasin Tablet 25 10's. Zemasin Tablet 25 10's should not be taken if you are pregnant or planning to become pregnant or breastfeeding. Zemasin Tablet 25 10's should not be given to children as safety has not been established.

Uses of Zemasin Tablet 25 10's

Zemasin Tablet 25 10's is used in the treatment of breast cancer in women. The detailed uses of Zemasin Tablet 25 10's are as follows:

  • Treats Breast Cancer in Postmenopausal Women: Zemasin Tablet 25 10's is used to treat early-stage, hormone receptor-positive breast cancer in women after menopause (cessation of periods) by reducing estrogen levels, which drives the growth of cancer cells.
  • Maintenance Therapy to Prevent Cancer Recurrence: Zemasin Tablet 25 10's is often prescribed after 2-3 years of tamoxifen therapy (hormone treatment) to reduce the risk of breast cancer recurrence by further suppressing estrogen production.
  • Treats Advanced or Metastatic Breast Cancer: Zemasin Tablet 25 10's is also used to treat advanced hormone receptor-positive breast cancer in postmenopausal women when other hormonal therapies have not been effective.

Key Benefits

  • Zemasin Tablet 25 10's is used to treat specific types of breast cancer in women after menopause.
  • Zemasin Tablet 25 10's is also used to help prevent cancer from returning. Some breast cancers are made to grow faster by a natural hormone known as estrogen.
  • Zemasin Tablet 25 10's works by blocking the aromatase enzyme, which is involved in producing the estrogen hormone.
  • Zemasin Tablet 25 10's lowers the amount of estrogen in the body.
  • Zemasin Tablet 25 10's helps prevent or stop the growth of the tumours (cancer cells) from spreading to other body parts.

Directions for Use

  • Zemasin Tablet 25 10's can be preferably taken after meals.
  • Take Zemasin Tablet 25 10's once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zemasin Tablet 25 10's Works

Zemasin Tablet 25 10's works by blocking the aromatase enzyme, which produces the estrogen hormone. Thus, it lowers the amount of estrogen (the natural female hormone) produced in the body. Cancer cells require estrogen for their growth. Hence, blocking the aromatase enzyme prevents the growth of cancer cells. Together, Zemasin Tablet 25 10's helps prevent or stop the spread of tumours (cancer cells) to other body parts.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Zemasin Tablet 25 10's to avoid unpleasant side effects. Alcohol intake, along with Zemasin Tablet 25 10's, may cause increased drowsiness.

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Pregnancy

Unsafe

Zemasin Tablet 25 10's should not be used during pregnancy because it causes harm to your fetus (newborn baby). Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Breast Feeding

Unsafe

Zemasin Tablet 25 10's should not be taken during breastfeeding as it may harm your baby. Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Driving

Unsafe

Zemasin Tablet 25 10's may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver diseases, please consult a doctor before taking Zemasin Tablet 25 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have or had a history or evidence of any kidney diseases, please consult a doctor before taking Zemasin Tablet 25 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Zemasin Tablet 25 10's should not be used by children, as efficacy and safety have not been established.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Zemasin Tablet 25 10's in elderly patients. Please consult your doctor.

What if I have taken an overdose of Zemasin Tablet 25 10's

Do not take more than the prescribed dose of Zemasin Tablet 25 10's as it may cause serious side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep, rest well.

Have a query?

How Soon It Starts Working

  • The time required for Zemasin Tablet 25 10's to start to work: The time required for Zemasin Tablet 25 10's to show its action is not clinically established. 
  • The time for which the effects of Zemasin Tablet 25 10's last: The duration of action for Zemasin Tablet 25 10's is not clinically established.

What if you forget to take Zemasin Tablet 25 10's

Take the missed dose as soon as you can. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not double the dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • To treat your condition effectually, continue taking Zemasin Tablet 25 10's for as long as your doctor has prescribed. Do not stop Zemasin Tablet 25 10's midway.
  • Do not take Zemasin Tablet 25 10's if you are allergic to any of its contents. $
  • Zemasin Tablet 25 10's should not be taken in conditions like liver and kidney disease.
  • Before taking Zemasin Tablet 25 10's inform your doctor if you have osteoporosis, as Zemasin Tablet 25 10's may increase your risk of developing osteoporosis. I
  • f you have not yet gone through menopause, i.e. if you still have periods, then immediately inform your doctor before taking Zemasin Tablet 25 10's.
  • Zemasin Tablet 25 10's should not be taken If you are pregnant or planning to become pregnant or breastfeeding.
  • Zemasin Tablet 25 10's causes weakness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol with Zemasin Tablet 25 10's as it could lead to increased drowsiness and dizziness.
  • Zemasin Tablet 25 10's should not be given to children as safety has not been established.
  • Zemasin Tablet 25 10's may have an intolerance to some sugar. Inform your doctor before taking this Zemasin Tablet 25 10's.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Zemasin Tablet 25 10's may interact with an antibiotic (rifampicin) and medicines used to treat fits/epilepsy (carbamazepine, phenytoin).

Food-Drug Interactions: No food interaction was found.

Drug-Disease Interactions: Zemasin Tablet 25 10's should not be given to patients with osteoporosis and vitamin D deficiency.

ExemestaneDienestrol
Severe
ExemestaneEstramustine
Severe

Drug-Drug Interactions

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ExemestaneDienestrol
Severe
How does the drug interact with Zemasin Tablet 25:
Co-administration of Zemasin Tablet 25 with Dienestrol may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Zemasin Tablet 25 and Dienestrol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneEstramustine
Severe
How does the drug interact with Zemasin Tablet 25:
Co-administration of Zemasin Tablet 25 with Estramustine may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Zemasin Tablet 25 and Estramustine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneConjugated Estrogens
Severe
How does the drug interact with Zemasin Tablet 25:
Coadministration of Conjugated estrogens with Zemasin Tablet 25 may reduce the effect of Zemasin Tablet 25.

How to manage the interaction:
Although taking Conjugated estrogen and Zemasin Tablet 25 together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
ExemestaneChlorotrianisene
Severe
How does the drug interact with Zemasin Tablet 25:
Co-administration of Zemasin Tablet 25 with Chlorotrianisene may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Zemasin Tablet 25 with Chlorotrianisene together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneDiethylstilbestrol
Severe
How does the drug interact with Zemasin Tablet 25:
Co-administration of Zemasin Tablet 25 with Diethylstilbestrol may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Zemasin Tablet 25 with Diethylstilbestrol together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneEstrone
Severe
How does the drug interact with Zemasin Tablet 25:
Co-administration of Zemasin Tablet 25 with Estrone may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
Co-administration of Zemasin Tablet 25 with Estrone can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneEstradiol
Severe
How does the drug interact with Zemasin Tablet 25:
Using Estradiol with Zemasin Tablet 25 may interfere with Zemasin Tablet 25's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Zemasin Tablet 25 and Estradiol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneThalidomide
Severe
How does the drug interact with Zemasin Tablet 25:
Taking thalidomide together with Zemasin Tablet 25 may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Zemasin Tablet 25 together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ExemestaneEthinylestradiol
Severe
How does the drug interact with Zemasin Tablet 25:
When used with Ethinylestradiol, the effectiveness of Zemasin Tablet 25 might be reduced.

How to manage the interaction:
Although taking Zemasin Tablet 25 and Ethinylestradiol together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Zemasin Tablet 25 10's is used to treat breast cancer in women who have gone through menopause (cessation of menses periods).
The most common side effects of using Zemasin Tablet 25 10's are hot flashes, joint pain, feeling tired, trouble sleeping, headache, depression, increased sweating, upset stomach, feeling anxious, and difficulty breathing. If any of these side effects disturb you, inform your doctor.
The common symptoms of breast cancer involve the presence of a lump in the breast that feels different from the rest of the breast tissue. You may observe changes in the size, shape and appearance of the breast. The nipple becomes enlarged and painful, and discharge is also one of the symptoms of breast cancer. Pain occurs around the breast.
Yes, Zemasin Tablet 25 10's commonly affects the hair by making it thin, which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Zemasin Tablet 25 10's. These effects are not long-lasting and may return after some time. If it matters to you, inform your doctor of another alternative medicine to avoid harm to your hair.
Zemasin Tablet 25 10's causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
Although there is no known way to prevent breast cancer, there are ways to lower your risk. It is advisable to drink less alcohol, stay at a healthy weight, get regular exercise, breastfeed (completely breastfeeding during your baby's first 6 months and continuing for 12 months or longer), and inform your doctor about hormone replacement therapy (a form of hormone therapy used to treat symptoms related with female menopause) if you take it.
Take Zemasin Tablet 25 10's with or without food as advised by your doctor. The number of doses and the duration depend on your medical condition. Take it roughly at the same time every day to ensure consistent levels of Zemasin Tablet 25 10's in your body. You may need to take Zemasin Tablet 25 10's for several years, and the treatment may be long-term.
If you forget to take a dose of Zemasin Tablet 25 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose on time. Do not double the dose to make up for the missed one, as this may increase the risk of side effects.
Zemasin Tablet 25 10's is safe if used as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects persist or worsen.
Do not stop taking Zemasin Tablet 25 10's without talking to your doctor, even if you feel better as it may worsen your condition.
Store Zemasin Tablet 25 10's at room temperature, protected from moisture. Keep it out of reach of children.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Exemestane Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.4664 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Exemestane Exemestane. 1999. [Accessed on 03 Apr. 2019] Check here
  4. Exemestane [Prescribing Information]. 2018. [Accessed on 20 Feb. 2024] Check here
  5. Giorgia Zucchini, Elena Geuna, Andrea Milani, Caterina Aversa, Rossella Martinello, and Filippo Montemurro. Clinical utility of exemestane in the treatment of breast cancer. International Journal of women’s health. May 2015. [Accessed on 14th May] Check here
  6. Glenmark Pharmaceuticals limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 14th May] Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 04 Apr. 2019]Check here

Country of origin

INDIA
Other Info - ZEM0064

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