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compositionComposition:EXEMESTANE-25MG
prescription
Prescription Medicine
info
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Xmalon 25 mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Exemestane, which prevents the growth of cancer cells. Thus, it helps to prevent the spreading of tumours (cancer cells) to other body parts. It may cause common side effects such as insomnia (difficulty sleeping), nausea, headache, musculoskeletal (bone, muscle, or joint) pain, increased sweating, and overtiredness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EXEMESTANE-25MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Xmalon 25 mg Tablet

Xmalon 25 mg Tablet is an oral prescription medication used to treat hormone-receptor-positive early and advanced breast cancer in women who have completed menopause. It is prescribed to help lower the risk of the cancer returning or spreading to other parts of the body. By targeting the hormones that some breast cancers need to grow, this medication plays a vital role in long-term cancer management.

This medication is typically taken once daily, and it is highly recommended to take it consistently at the same time each day to maintain steady levels in your body. You should take Xmalon 25 mg Tablet with food, preferably after a meal, as this significantly improves how well your body absorbs the medicine. To support your overall health and bone strength during treatment, your doctor may suggest incorporating weight-bearing exercises and a calcium-rich diet into your daily routine.

Common side effects of this medication include hot flashes, joint pain, muscle stiffness, and feeling unusually tired. While these are often mild, you must consult your doctor immediately if you experience serious side effects, such as sudden chest pain, shortness of breath, or signs of liver damage like yellowing of your skin or eyes.

Before starting Xmalon 25 mg Tablet , talk to your doctor if you have a history of osteoporosis, liver disease, or kidney problems. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm an unborn baby. This treatment is strictly intended for women who have already gone through menopause.

Some medications, including oestrogens, herbal supplements like St. John's wort, and certain anti-seizure drugs, can interact with Xmalon 25 mg Tablet and reduce its effectiveness. It is also wise to discuss your alcohol consumption with your doctor, as regular drinking can worsen bone thinning. Always consult your healthcare provider if you belong to specific patient groups, such as elderly individuals with pre-existing bone conditions, to ensure safe monitoring.

Uses of Xmalon 25 mg Tablet

Xmalon 25 mg Tablet is used to treat hormone-receptor-positive early and advanced breast cancer in women who have completed menopause. The detailed uses of Xmalon 25 mg Tablet are as follows:

  • Early breast cancer: It is used to treat hormone-receptor-positive early breast cancer in postmenopausal women, often after they have completed 2 to 3 years of tamoxifen therapy, to help prevent the cancer from returning.
  • Advanced breast cancer: It is prescribed to treat advanced breast cancer in postmenopausal women whose disease has progressed or returned after undergoing other initial hormone therapies.

Key Benefits

Xmalon 25 mg Tablet helps treat hormone receptor-positive breast cancer by lowering the body's oestrogen levels. By reducing the hormone that fuels the growth of certain breast cancer cells, it supports long-term cancer treatment and helps reduce the risk of recurrence.

  • Helps Slow the Growth of Breast Cancer: By lowering oestrogen levels, Xmalon 25 mg Tablet helps slow or stop the growth of hormone-sensitive breast cancer cells, supporting effective cancer management.
  • Helps Reduce the Risk of Cancer Recurrence: When used as prescribed after initial treatment, Xmalon 25 mg Tablet helps lower the likelihood of breast cancer returning, supporting long-term recovery and disease control.
  • Offers Convenient Long-Term Treatment: As a once-daily oral tablet, Xmalon 25 mg Tablet provides a convenient treatment option that can be taken at home, making it easier to maintain consistent therapy over the recommended treatment period.
Side effects of Xmalon 25 mg Tablet
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • If you notice any changes in your blood test results, especially if you are taking medicines that can affect clotting time, consult your doctor so that they may adjust the dose or recommend alternative medicine with lower risk.
  • Be aware of possible signs like nosebleeds, easy bruising, or heavy menstrual bleeding.
  • Consult your doctor to determine potential causes of increased PTT (Partial thromboplastin time), such as clotting factor deficiencies or medication effects, and recommend appropriate treatment.
  • Your doctor may adjust medications if they are causing increased PTT.
  • Eat vitamin K-rich foods like leafy greens and essential nutrients to support normal blood clotting.
  • Take precautions like wearing protective gear to prevent injuries.
  • Inform your doctor if you experience severe bleeding, such as heavy periods or bleeding that doesn’t stop after 10–15 minutes of pressure.
  • Be alert for symptoms of bleeding, such as easy bruising, extended bleeding from cuts, gum or nosebleeds, heavy menstrual periods, or blood in your stool or urine.
  • Follow your doctor's advice regarding blood-thinning medications.
  • Limit foods that are high in vitamin K, such as kale, spinach, broccoli, and Brussels sprouts, if your doctor advises.
  • Avoid activities that may lead to injury or increase bleeding risks.
  • If you suspect severe bleeding, seek medical help right away.
  • Follow regular check-ups to assess your blood clotting status and any necessary modifications to your treatment.

Directions for Use

  • Xmalon 25 mg Tablet can be preferably taken after meals.
  • Take Xmalon 25 mg Tablet once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Xmalon 25 mg Tablet Works

Many breast cancer cells have hormone receptors and require oestrogen to grow and multiply. In women who have gone through menopause, oestrogen is no longer produced by the ovaries. Instead, an enzyme in the body called aromatase converts other hormones into oestrogen in tissues like fat and muscle. Xmalon 25 mg Tablet contains exemestane, which works by binding to and permanently blocking the aromatase enzyme, which stops it from making oestrogen. By lowering the amount of oestrogen in your body, the medication starves the cancer cells of the hormone they need to grow, helping to shrink tumours or prevent them from returning.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Xmalon 25 mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Xmalon 25 mg Tablet , may cause increased drowsiness.

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Pregnancy

Unsafe

Xmalon 25 mg Tablet should not be used during pregnancy because it causes harm to your fetus (newborn baby). Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Breast Feeding

Unsafe

Xmalon 25 mg Tablet should not be taken during breastfeeding as it may harm your baby. Please consult your doctor about any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it.

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Driving

Unsafe

Xmalon 25 mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

If you have or had a history or evidence of any liver diseases, please consult a doctor before taking Xmalon 25 mg Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have or had a history or evidence of any kidney diseases, please consult a doctor before taking Xmalon 25 mg Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Xmalon 25 mg Tablet should not be used by children, as efficacy and safety have not been established.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Xmalon 25 mg Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Xmalon 25 mg Tablet

If you suspect an overdose or have taken more than your prescribed dose, seek emergency medical attention immediately.

Diet & Lifestyle Advise

  • Protect your bone health: Because Xmalon 25 mg Tablet lowers oestrogen, it can weaken your bones. Ensure your diet includes plenty of calcium and vitamin D, found in dairy products, leafy greens, and fortified foods, or speak to your doctor about appropriate supplements.
  • Engage in weight-bearing exercise: Regular physical activities such as walking, light jogging, or strength training help maintain bone density and support joint flexibility during your therapy.
  • Eat a heart-healthy diet: Focus on a balanced diet rich in fiber, whole grains, and lean proteins while limiting saturated fats to help manage your cholesterol levels, which can sometimes fluctuate during hormone therapy.
  • Manage hot flashes: Wear layers of breathable clothing, keep your living space cool, and limit spicy foods, caffeine, and alcohol, as these can trigger or worsen hot flashes.
health query

Have a query?

How Soon It Starts Working

  • The time required for Xmalon 25 mg Tablet to start to work: The time required for Xmalon 25 mg Tablet to show its action is not clinically established.
  • The time for which the effects of Xmalon 25 mg Tablet last: The duration of action for Xmalon 25 mg Tablet is not clinically established.

What if you forget to take Xmalon 25 mg Tablet

If you miss a dose of Xmalon 25 mg Tablet , take it with food as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose entirely and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Xmalon 25 mg Tablet tablets at room temperature, strictly between 20°C and 25°C (68°F and 77°F). •Keep the medicine in its original blister pack or container to protect it from moisture and direct light.

Drug Warnings

  • Always take Xmalon 25 mg Tablet with food to ensure your body absorbs the medication properly.
  • Schedule regular bone density scans (DEXA scans) with your doctor to monitor your bone health and catch any thinning early.
  • Undergo routine blood tests as requested by your doctor to check your cholesterol levels, liver function, and kidney health.
  • Inform all healthcare providers you visit, including your dentist, that you are taking Xmalon 25 mg Tablet before undergoing any medical or dental procedures.
  • Do not start any new prescription medicines, over-the-counter drugs, or herbal products without checking with your pharmacist to prevent dangerous interactions.

Drug-Drug Interactions

verifiedApollotooltip
  • Oestrogen-containing therapies: Medicines such as hormone replacement therapy (HRT) or birth control pills can reverse the effects of Xmalon 25 mg Tablet , making it less effective. Do not take these treatments together.
  • Certain anti-seizure medicines (such as phenytoin or carbamazepine) and rifampicin: These medications can cause your body to break down Xmalon 25 mg Tablet more quickly, which can lower its strength and effectiveness in your system.
  • St. John's wort: This herbal supplement can speed up the clearance of Xmalon 25 mg Tablet from your body, reducing its ability to treat your condition.
ExemestaneDiethylstilbestrol
Severe
ExemestaneEstradiol
Severe

Drug-Drug Interactions

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ExemestaneDiethylstilbestrol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Diethylstilbestrol may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xmalon 25 mg Tablet with Diethylstilbestrol together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneEstradiol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Using Estradiol with Xmalon 25 mg Tablet may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xmalon 25 mg Tablet and Estradiol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneChlorotrianisene
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Chlorotrianisene may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xmalon 25 mg Tablet with Chlorotrianisene together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneThalidomide
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Taking thalidomide together with Xmalon 25 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Xmalon 25 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ExemestaneConjugated Estrogens
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Coadministration of Conjugated estrogens with Xmalon 25 mg Tablet may reduce the effect of Xmalon 25 mg Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Xmalon 25 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
ExemestaneEstramustine
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Estramustine may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Xmalon 25 mg Tablet and Estramustine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneDienestrol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Dienestrol may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xmalon 25 mg Tablet and Dienestrol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneEthinylestradiol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
When used with Ethinylestradiol, the effectiveness of Xmalon 25 mg Tablet might be reduced.

How to manage the interaction:
Although taking Xmalon 25 mg Tablet and Ethinylestradiol together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ExemestaneEstrone
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Estrone may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Co-administration of Xmalon 25 mg Tablet with Estrone can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Xmalon 25 mg Tablet when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Xmalon 25 mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of menses periods).
The most common side effects of using Xmalon 25 mg Tablet are hot flashes, joint pain, feeling tired, trouble sleeping, headache, depression, increased sweating, upset stomach, feeling anxious, and difficulty breathing. If any of these side effects disturb you, inform your doctor.
The common symptoms of breast cancer involve the presence of a lump in the breast that feels different from the rest of the breast tissue. You may observe changes in the size, shape and appearance of the breast. The nipple becomes enlarged and painful, and discharge is also one of the symptoms of breast cancer. Pain occurs around the breast.
Yes, Xmalon 25 mg Tablet commonly affects the hair by making it thin, which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xmalon 25 mg Tablet . These effects are not long-lasting and may return after some time. If it matters to you, inform your doctor of another alternative medicine to avoid harm to your hair.
Xmalon 25 mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
Xmalon 25 mg Tablet is safe if used as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects persist or worsen.
Do not stop taking Xmalon 25 mg Tablet without talking to your doctor, even if you feel better as it may worsen your condition.
Store Xmalon 25 mg Tablet at room temperature, protected from moisture. Keep it out of reach of children.
No, Xmalon 25 mg Tablet is only designed for women who have fully gone through menopause. It is not effective in women whose ovaries are still actively producing oestrogen. Talk to your doctor to determine the right treatment for your menopausal status.
Taking this medication with food, especially after a meal, helps your digestive system absorb the active ingredients much better. This ensures that you get the full therapeutic benefit of each dose. Talk to your doctor or pharmacist if you struggle to take it with meals.
The duration of your treatment depends entirely on your specific cancer stage, history, and how well you tolerate the medication. Many patients take it for several years as part of a long-term care plan. Talk to your doctor about your personalised treatment timeline.
Yes, joint and muscle pain or stiffness are common side effects of this medication because of the reduction of oestrogen levels in your body. Regular gentle exercise, staying hydrated, or mild pain relievers can help manage this discomfort. Talk to your doctor if your joint pain becomes severe or interferes with your daily activities.
Yes, because this medicine lowers oestrogen levels, it can lead to a decrease in bone density, which may increase your risk of bone thinning or fractures over time. Your healthcare provider may monitor your bone health using specialised scans. Talk to your doctor about calcium and vitamin D supplements to help protect your bones.
There is no direct chemical interaction between alcohol and Xmalon 25 mg Tablet , but moderate to heavy alcohol intake can accelerate bone loss and worsen hot flashes. It is generally best to limit your alcohol consumption during treatment. Talk to your doctor about safe alcohol limits for you.
If you miss a dose, take it with food as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue with your normal routine. Talk to your doctor or pharmacist if you frequently miss doses or need help managing your schedule.
No, you must avoid taking oestrogen supplements, hormone replacement therapies, or using vaginal oestrogen creams while on this medication. Oestrogen will directly oppose how this medicine works, making your breast cancer treatment much less effective. Talk to your doctor before starting any new medications or supplements.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Exemestane Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.4664 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Exemestane Exemestane. 1999. [Accessed on 03 Apr. 2019]Check here
  4. Exemestane [Prescribing Information]. 2018. [Accessed on 20 Feb. 2024]Check here
  5. Giorgia Zucchini, Elena Geuna, Andrea Milani, Caterina Aversa, Rossella Martinello, and Filippo Montemurro. Clinical utility of exemestane in the treatment of breast cancer. International Journal of women’s health. May 2015. [Accessed on 14th May]Check here
  6. Glenmark Pharmaceuticals limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 14th May]Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 04 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - XMA0005
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